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Volumn 14, Issue 1, 2014, Pages 29-38

Pharmacotherapy of generalized anxiety disorder: Focus and update on pregabalin

Author keywords

Anxiolytic; Drug therapy; Generalized anxiety disorder; Pregabalin; Randomized controlled trials

Indexed keywords

AGOMELATINE; ALPRAZOLAM; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; BENZODIAZEPINE DERIVATIVE; BUSPIRONE; CLOMIPRAMINE; DIAZEPAM; DULOXETINE; ESCITALOPRAM; HYDROXYZINE; IMIPRAMINE; LORAZEPAM; PAROXETINE; PREGABALIN; QUETIAPINE; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRAZODONE; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE;

EID: 84893062478     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/14737175.2014.853617     Document Type: Review
Times cited : (12)

References (77)
  • 1
    • 80052376956 scopus 로고    scopus 로고
    • The size and burden of mental disorders and other disorders of the brain in europe 2010
    • Wittchen HU, Jacobi F, Rehm J et al. The size and burden of mental disorders and other disorders of the brain in Europe 2010. Eur. Neuropsychopharmacol. 21(9), 655-679 (2011
    • (2011) Eur. Neuropsychopharmacol , vol.21 , Issue.9 , pp. 655-679
    • Wittchen, H.U.1    Jacobi, F.2    Rehm, J.3
  • 2
    • 20344385026 scopus 로고    scopus 로고
    • Lifetime prevalence and age-of-onset distributions of dsm-iv disorders in the national comorbidity survey replication
    • Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch. Gen. Psychiatry 62(6), 593-602 (2005
    • (2005) Arch. Gen. Psychiatry , vol.62 , Issue.6 , pp. 593-602
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Merikangas, K.R.5    Walters, E.E.6
  • 3
    • 84870566561 scopus 로고    scopus 로고
    • Generalized anxiety disorder: Diagnosis and treatment
    • GAD
    • Hoge EA, Ivkovic A, Fricchione GL. Generalized anxiety disorder: Diagnosis and treatment. BMJ 345, e7500 (2012). (GAD
    • (2012) BMJ , vol.345
    • Hoge, E.A.1    Ivkovic, A.2    Fricchione, G.L.3
  • 4
    • 44849113507 scopus 로고    scopus 로고
    • Duration of untreated illness as a predictor of treatment response and clinical course in generalized anxiety disorder
    • Altamura AC, Dell'osso B, D'Urso N, Russo M, Fumagalli S, Mundo E. Duration of untreated illness as a predictor of treatment response and clinical course in generalized anxiety disorder. CNS Spectr. 13(5), 415-422 (2008
    • (2008) CNS Spectr , vol.13 , Issue.5 , pp. 415-422
    • Altamura, A.C.1    Dell'Osso, B.2    D'Urso, N.3    Russo, M.4    Fumagalli, S.5    Mundo, E.6
  • 5
    • 78650571322 scopus 로고    scopus 로고
    • Management of generalized anxiety disorder in primary care: Identifying the challenges and unmet needs
    • Davidson JR, Feltner DE, Dugar A. Management of generalized anxiety disorder in primary care: Identifying the challenges and unmet needs. Prim. Care Companion. J. Clin. Psychiatry 12(2) (2010
    • (2010) Prim. Care Companion. J. Clin. Psychiatry , vol.12 , Issue.2
    • Davidson, J.R.1    Feltner, D.E.2    Dugar, A.3
  • 6
    • 13244291284 scopus 로고    scopus 로고
    • Early traumatic life events, parental rearing styles, family history of mental disorders, and birth risk factors in patients with social anxiety disorder
    • Bandelow B, Charimo TA, Wedekind D, Broocks A, Hajak G, Ruther E. Early traumatic life events, parental rearing styles, family history of mental disorders, and birth risk factors in patients with social anxiety disorder. Eur. Arch. Psychiatry Clin. Neurosci 254(6), 397-405 (2004
    • (2004) Eur. Arch. Psychiatry Clin. Neurosci , vol.254 , Issue.6 , pp. 397-405
    • Bandelow, B.1    Charimo, T.A.2    Wedekind, D.3    Broocks, A.4    Hajak, G.5    Ruther, E.6
  • 7
    • 79959293688 scopus 로고    scopus 로고
    • The structural and functional connectivity of the amygdala: Farom normal emotion to pathological anxiety
    • Kim MJ, Loucks RA, Palmer AL et al. The structural and functional connectivity of the amygdala: Farom normal emotion to pathological anxiety. Behav. Brain Res. 223(2), 403-410 (2011
    • (2011) Behav. Brain Res , vol.223 , Issue.2 , pp. 403-410
    • Kim, M.J.1    Loucks, R.A.2    Palmer, A.L.3
  • 8
    • 79952608431 scopus 로고    scopus 로고
    • Altered cerebral blood flow patterns associated with pathologic worry in the elderly
    • Andreescu C, Gross JJ, Lenze E et al. Altered cerebral blood flow patterns associated with pathologic worry in the elderly. Depress. Anxiety 28(3), 202-209 (2011
    • (2011) Depress. Anxiety , vol.28 , Issue.3 , pp. 202-209
    • Andreescu, C.1    Gross, J.J.2    Lenze, E.3
  • 9
    • 0141517336 scopus 로고    scopus 로고
    • Neuroanatomical circuits modulating fear and anxiety behaviors
    • Charney DS. Neuroanatomical circuits modulating fear and anxiety behaviors. Acta Psychiatr. Scand. Suppl. (417), 38-50 (2003
    • (2003) Acta Psychiatr. Scand. Suppl. , vol.417 , pp. 38-50
    • Charney, D.S.1
  • 10
    • 0026443999 scopus 로고
    • Anger and anxiety responses to m-chlorophenylpiperazine in generalized anxiety disorder
    • Germine M, Goddard AW, Woods SW, Charney DS, Heninger GR. Anger and anxiety responses to m-chlorophenylpiperazine in generalized anxiety disorder. Biol. Psychiatry 32(5), 457-461 (1992
    • (1992) Biol. Psychiatry , vol.32 , Issue.5 , pp. 457-461
    • Germine, M.1    Goddard, A.W.2    Woods, S.W.3    Charney, D.S.4    Heninger, G.R.5
  • 11
    • 84884588884 scopus 로고    scopus 로고
    • Interaction between polymorphisms in serotonin transporter (SLC6A4) and serotonin receptor 2A (HTR2A) genes predict treatment response to venlafaxine XR in generalized anxiety disorder
    • Lohoff FW, Narasimhan S, Rickels K. Interaction between polymorphisms in serotonin transporter (SLC6A4) and serotonin receptor 2A (HTR2A) genes predict treatment response to venlafaxine XR in generalized anxiety disorder. Pharmacogenomics. J. 13(5), 464-469 (2012
    • (2012) Pharmacogenomics. J. , vol.13 , Issue.5 , pp. 464-469
    • Lohoff, F.W.1    Narasimhan, S.2    Rickels, K.3
  • 12
    • 77952356320 scopus 로고    scopus 로고
    • Salivary cortisol levels in persons with and without different anxiety disorders
    • Vreeburg SA, Zitman FG, van PJ et al. Salivary cortisol levels in persons with and without different anxiety disorders. Psychosom. Med. 72(4), 340-347 (2010
    • (2010) Psychosom. Med , vol.72 , Issue.4 , pp. 340-347
    • Vreeburg, S.A.1    Zitman, F.G.2    Van, P.J.3
  • 13
    • 79960358382 scopus 로고    scopus 로고
    • Polymorphic variation at the serotonin 1-A receptor gene is associated with comorbid depression and generalized anxiety
    • Molina E, Cervilla J, Rivera M et al. Polymorphic variation at the serotonin 1-A receptor gene is associated with comorbid depression and generalized anxiety. Psychiatr. Genet. 21(4), 195-201 (2011
    • (2011) Psychiatr. Genet , vol.21 , Issue.4 , pp. 195-201
    • Molina, E.1    Cervilla, J.2    Rivera, M.3
  • 14
    • 84873020837 scopus 로고    scopus 로고
    • Evidence-based review of clinical outcomes of guideline-recommended pharmacotherapies for generalized anxiety disorder
    • Bereza BG, Machado M, Ravindran AV, Einarson TR. Evidence-based review of clinical outcomes of guideline-recommended pharmacotherapies for generalized anxiety disorder. Can. J. Psychiatry 57(8), 470-478 (2012
    • (2012) Can. J. Psychiatry , vol.57 , Issue.8 , pp. 470-478
    • Bereza, B.G.1    MacHado, M.2    Ravindran, A.V.3    Einarson, T.R.4
  • 15
    • 84860855073 scopus 로고    scopus 로고
    • Guidelines for the pharmacological treatment of anxiety disorders, obsessive-compulsive disorder and posttraumatic stress disorder in primary care
    • Bandelow B, Sher L, Bunevicius R et al. Guidelines for the pharmacological treatment of anxiety disorders, obsessive-compulsive disorder and posttraumatic stress disorder in primary care. Int. J. Psychiatry Clin. Pract. 16(2), 77-84 (2012
    • (2012) Int. J. Psychiatry Clin. Pract , vol.16 , Issue.2 , pp. 77-84
    • Bandelow, B.1    Sher, L.2    Bunevicius, R.3
  • 16
    • 79956057325 scopus 로고    scopus 로고
    • Evidence-based pharmacological treatment of generalized anxiety disorder
    • Baldwin DS, Waldman S, Allgulander C. Evidence-based pharmacological treatment of generalized anxiety disorder. Int. J. Neuropsychopharmacol. 14(5), 697-710 (2011
    • (2011) Int. J. Neuropsychopharmacol , vol.14 , Issue.5 , pp. 697-710
    • Baldwin, D.S.1    Waldman, S.2    Allgulander, C.3
  • 17
    • 84875658843 scopus 로고    scopus 로고
    • Efficacy of the novel antidepressant agomelatine for anxiety symptoms in major depression
    • Stein DJ, Picarel-Blanchot F, Kennedy SH. Efficacy of the novel antidepressant agomelatine for anxiety symptoms in major depression. Hum. Psychopharmacol. 28(2), 151-159 (2013
    • (2013) Hum. Psychopharmacol , vol.28 , Issue.2 , pp. 151-159
    • Stein, D.J.1    Picarel-Blanchot, F.2    Kennedy, S.H.3
  • 18
    • 84864403936 scopus 로고    scopus 로고
    • Agomelatine prevents relapse in generalized anxiety disorder: A 6-month randomized, double-blind, placebocontrolled discontinuation study
    • Stein DJ, Ahokas A, Albarran C, Olivier V, Allgulander C. Agomelatine prevents relapse in generalized anxiety disorder: A 6-month randomized, double-blind, placebocontrolled discontinuation study. J. Clin. Psychiatry 73(7), 1002-1008 (2012
    • (2012) J. Clin. Psychiatry , vol.73 , Issue.7 , pp. 1002-1008
    • Stein, D.J.1    Ahokas, A.2    Albarran, C.3    Olivier, V.4    Allgulander, C.5
  • 19
    • 84863717569 scopus 로고    scopus 로고
    • Agomelatine versus venlafaxine XR in the treatment of anhedonia in major depressive disorder: A pilot study
    • Martinotti G, Sepede G, Gambi F et al. Agomelatine versus venlafaxine XR in the treatment of anhedonia in major depressive disorder: A pilot study. J. Clin. Psychopharmacol. 32(4), 487-491 (2012
    • (2012) J. Clin. Psychopharmacol , vol.32 , Issue.4 , pp. 487-491
    • Martinotti, G.1    Sepede, G.2    Gambi, F.3
  • 21
    • 4644336231 scopus 로고    scopus 로고
    • The role of GABA in the pathophysiology and treatment of anxiety disorders
    • Nemeroff CB. The role of GABA in the pathophysiology and treatment of anxiety disorders. Psychopharmacol. Bull. 37(4), 133-146 (2003
    • (2003) Psychopharmacol. Bull , vol.37 , Issue.4 , pp. 133-146
    • Nemeroff, C.B.1
  • 22
    • 8144229157 scopus 로고    scopus 로고
    • Generalized anxiety disorder: Acute and chronic treatment
    • Rynn MA, Brawman-Mintzer O. Generalized anxiety disorder: Acute and chronic treatment. CNS Spectr. 9(10), 716-723 (2004
    • (2004) CNS Spectr , vol.9 , Issue.10 , pp. 716-723
    • Rynn, M.A.1    Brawman-Mintzer, O.2
  • 23
    • 84860855073 scopus 로고    scopus 로고
    • Guidelines for the pharmacological treatment of anxiety disorders, obsessive-compulsive disorder and posttraumatic stress disorder in primary care
    • Bandelow B, Sher L, Bunevicius R et al. Guidelines for the pharmacological treatment of anxiety disorders, obsessive-compulsive disorder and posttraumatic stress disorder in primary care. Int. J. Psychiatry Clin. Pract. 16(2), 77-84 (2012
    • (2012) Int. J. Psychiatry Clin. Pract , vol.16 , Issue.2 , pp. 77-84
    • Bandelow, B.1    Sher, L.2    Bunevicius, R.3
  • 24
    • 79957748356 scopus 로고    scopus 로고
    • Treatment of generalized anxiety disorder: A comprehensive review of the literature for psychopharmacologic alternatives to newer antidepressants and benzodiazepines
    • Huh J, Goebert D, Takeshita J, Lu BY, Kang M. Treatment of generalized anxiety disorder: A comprehensive review of the literature for psychopharmacologic alternatives to newer antidepressants and benzodiazepines. Prim. Care Companion. CNS Disord. 13(2), (2011
    • (2011) Prim. Care Companion. CNS Disord , vol.13 , Issue.2
    • Huh, J.1    Goebert, D.2    Takeshita, J.3    Lu, B.Y.4    Kang, M.5
  • 25
    • 84893067724 scopus 로고    scopus 로고
    • Non-antidepressant treatment of generalized anxiety disorder
    • Epub ahead of print
    • Zahreddine N, Richa S. Non-antidepressant treatment of generalized anxiety disorder. Curr. Clin. Pharmacol. (2013) (Epub ahead of print
    • (2013) Curr. Clin. Pharmacol.
    • Zahreddine, N.1    Richa, S.2
  • 26
    • 0031712911 scopus 로고    scopus 로고
    • A multicentre double-blind comparison of hydroxyzine, buspirone and placebo in patients with generalized anxiety disorder
    • Lader M, Scotto JC. A multicentre double-blind comparison of hydroxyzine, buspirone and placebo in patients with generalized anxiety disorder. Psychopharmacology (Berl) 139(4), 402-406 (1998
    • (1998) Psychopharmacology (Berl , vol.139 , Issue.4 , pp. 402-406
    • Lader, M.1    Scotto, J.C.2
  • 28
    • 0035125294 scopus 로고    scopus 로고
    • Cognitive theories of generalized anxiety disorder
    • vi
    • Aikins DE, Craske MG. Cognitive theories of generalized anxiety disorder. Psychiatr. Clin. North Am. 24(1), 57-74, vi (2001
    • (2001) Psychiatr. Clin. North Am. , vol.24 , Issue.1 , pp. 57-74
    • Aikins, D.E.1    Craske, M.G.2
  • 29
    • 44849141238 scopus 로고    scopus 로고
    • Cognitivebehavioral therapy for adult anxiety disorders: A meta-analysis of randomized placebo-controlled trials
    • Hofmann SG, Smits JA. Cognitivebehavioral therapy for adult anxiety disorders: A meta-analysis of randomized placebo-controlled trials. J. Clin. Psychiatry 69(4), 621-632 (2008
    • (2008) J. Clin. Psychiatry , vol.69 , Issue.4 , pp. 621-632
    • Hofmann, S.G.1    Smits, J.A.2
  • 30
    • 33845450824 scopus 로고    scopus 로고
    • Generalised anxiety disorder
    • Tyrer P, Baldwin D. Generalised anxiety disorder. Lancet 368(9553), 2156-2166 (2006
    • (2006) Lancet , vol.368 , Issue.9553 , pp. 2156-2166
    • Tyrer, P.1    Baldwin, D.2
  • 31
    • 47749115704 scopus 로고    scopus 로고
    • A preliminary study of fMRI-guided rTMS in the treatment of generalized anxiety disorder
    • Bystritsky A, Kaplan JT, Feusner JD et al. A preliminary study of fMRI-guided rTMS in the treatment of generalized anxiety disorder. J. Clin. Psychiatry 69(7), 1092-1098 (2008
    • (2008) J. Clin. Psychiatry , vol.69 , Issue.7 , pp. 1092-1098
    • Bystritsky, A.1    Kaplan, J.T.2    Feusner, J.D.3
  • 32
    • 64149103097 scopus 로고    scopus 로고
    • A preliminary study of fMRI-guided rTMS in the treatment of generalized anxiety disorder: 6-month follow-up
    • Bystritsky A, Kerwin LE, Feusner JD. A preliminary study of fMRI-guided rTMS in the treatment of generalized anxiety disorder: 6-month follow-up. J. Clin. Psychiatry 70(3), 431-432 (2009
    • (2009) J. Clin. Psychiatry , vol.70 , Issue.3 , pp. 431-432
    • Bystritsky, A.1    Kerwin, L.E.2    Feusner, J.D.3
  • 33
    • 34447115669 scopus 로고    scopus 로고
    • Pregabalin for the treatment of generalized anxiety disorder: A novel pharmacologic intervention
    • Bandelow B, Wedekind D, Leon T. Pregabalin for the treatment of generalized anxiety disorder: A novel pharmacologic intervention. Expert Rev. Neurother. 7(7), 769-781 (2007
    • (2007) Expert Rev. Neurother , vol.7 , Issue.7 , pp. 769-781
    • Bandelow, B.1    Wedekind, D.2    Leon, T.3
  • 34
    • 77950911515 scopus 로고    scopus 로고
    • Pregabalin in outpatient detoxification of subjects with mild-to-moderate alcohol withdrawal syndrome
    • Di Nicola M, Martinotti G, Tedeschi D et al. Pregabalin in outpatient detoxification of subjects with mild-to-moderate alcohol withdrawal syndrome. Hum. Psychopharmacol. 25(3), 268-275 (2010
    • (2010) Hum. Psychopharmacol , vol.25 , Issue.3 , pp. 268-275
    • Di Nicola, M.1    Martinotti, G.2    Tedeschi, D.3
  • 35
    • 74249108901 scopus 로고    scopus 로고
    • Pregabalin, tiapride and lorazepam in alcohol withdrawal syndrome: A multicentre, randomized, single-blind comparison trial
    • Martinotti G, Di NM, Frustaci A et al. Pregabalin, tiapride and lorazepam in alcohol withdrawal syndrome: A multicentre, randomized, single-blind comparison trial. Addiction 105(2), 288-299 (2010
    • (2010) Addiction , vol.105 , Issue.2 , pp. 288-299
    • Martinotti, G.1    Di, N.M.2    Frustaci, A.3
  • 36
    • 84862291441 scopus 로고    scopus 로고
    • Efficacy and safety of pregabalin in the treatment of alcohol and benzodiazepine dependence
    • Oulis P, Konstantakopoulos G. Efficacy and safety of pregabalin in the treatment of alcohol and benzodiazepine dependence. Expert Opin. Investig. Drugs 21(7), 1019-1029 (2012
    • (2012) Expert Opin. Investig. Drugs , vol.21 , Issue.7 , pp. 1019-1029
    • Oulis, P.1    Konstantakopoulos, G.2
  • 37
    • 79951512040 scopus 로고    scopus 로고
    • Efficacy and safety of treatments for refractory generalized anxiety disorder: A systematic review
    • Samuel M, Zimovetz EA, Gabriel Z, Beard SM. Efficacy and safety of treatments for refractory generalized anxiety disorder: A systematic review. Int. Clin. Psychopharmacol. 26(2), 63-68 (2011
    • (2011) Int. Clin. Psychopharmacol , vol.26 , Issue.2 , pp. 63-68
    • Samuel, M.1    Zimovetz, E.A.2    Gabriel, Z.3    Beard, S.M.4
  • 38
    • 54949154218 scopus 로고    scopus 로고
    • World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders - First revision
    • Bandelow B, Zohar J, Hollander E et al. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders - first revision. World J. Biol. Psychiatry 9(4), 248-312 (2008
    • (2008) World J. Biol. Psychiatry , vol.9 , Issue.4 , pp. 248-312
    • Bandelow, B.1    Zohar, J.2    Hollander, E.3
  • 39
    • 33846520548 scopus 로고    scopus 로고
    • Ca2+ channel alpha2delta ligands: Novel modulators of neurotransmission
    • Dooley DJ, Taylor CP, Donevan S, Feltner D. Ca2+ channel alpha2delta ligands: Novel modulators of neurotransmission. Trends Pharmacol. Sci. 28(2), 75-82 (2007
    • (2007) Trends Pharmacol. Sci , vol.28 , Issue.2 , pp. 75-82
    • Dooley, D.J.1    Taylor, C.P.2    Donevan, S.3    Feltner, D.4
  • 40
    • 33947254401 scopus 로고    scopus 로고
    • Pregabalin: A novel gamma-aminobutyric acid analogue in the treatment of neuropathic pain, partial-onset seizures, and anxiety disorders
    • Tassone DM, Boyce E, Guyer J, Nuzum D. Pregabalin: A novel gamma-aminobutyric acid analogue in the treatment of neuropathic pain, partial-onset seizures, and anxiety disorders. Clin. Ther. 29(1), 26-48 (2007
    • (2007) Clin. Ther , vol.29 , Issue.1 , pp. 26-48
    • Tassone, D.M.1    Boyce, E.2    Guyer, J.3    Nuzum, D.4
  • 41
    • 4544252052 scopus 로고    scopus 로고
    • Mechanism of action of alpha2delta ligands: Voltage sensitive calcium channel (VSCC) modulators
    • Stahl SM. Mechanism of action of alpha2delta ligands: Voltage sensitive calcium channel (VSCC) modulators. J. Clin. Psychiatry 65(8), 1033-1034 (2004
    • (2004) J. Clin. Psychiatry , vol.65 , Issue.8 , pp. 1033-1034
    • Stahl, S.M.1
  • 42
    • 84860112471 scopus 로고    scopus 로고
    • Switching from long-term benzodiazepine therapy to pregabalin in patients with generalized anxiety disorder: A double-blind, placebo-controlled trial
    • Hadley SJ, Mandel FS, Schweizer E. Switching from long-term benzodiazepine therapy to pregabalin in patients with generalized anxiety disorder: A double-blind, placebo-controlled trial. J. Psychopharmacol. 26(4), 461-470 (2012
    • (2012) J. Psychopharmacol , vol.26 , Issue.4 , pp. 461-470
    • Hadley, S.J.1    Mandel, F.S.2    Schweizer, E.3
  • 44
    • 27244438199 scopus 로고    scopus 로고
    • Pharmacokinetics of gabapentin during delivery in the neonatal period, and lactation: Does a fetal accumulation occur during pregnancy?
    • Ohman I, Vitols S, Tomson T. Pharmacokinetics of gabapentin during delivery, in the neonatal period, and lactation: Does a fetal accumulation occur during pregnancy? Epilepsia 46(10), 1621-1624 (2005
    • (2005) Epilepsia , vol.46 , Issue.10 , pp. 1621-1624
    • Ohman, I.1    Vitols, S.2    Tomson, T.3
  • 45
    • 33947223462 scopus 로고    scopus 로고
    • Pharmacokinetics and therapeutic drug monitoring of newer antiepileptic drugs during pregnancy and the puerperium
    • Tomson T, Battino D. Pharmacokinetics and therapeutic drug monitoring of newer antiepileptic drugs during pregnancy and the puerperium. Clin. Pharmacokinet. 46(3), 209-219 (2007
    • (2007) Clin. Pharmacokinet , vol.46 , Issue.3 , pp. 209-219
    • Tomson, T.1    Battino, D.2
  • 46
    • 0037461323 scopus 로고    scopus 로고
    • Pregabalin for the treatment of postherpetic neuralgia: A randomized, placebo-controlled trial
    • Dworkin RH, Corbin AE, Young JP Jr et al. Pregabalin for the treatment of postherpetic neuralgia: A randomized, placebo-controlled trial. Neurology 60(8), 1274-1283 (2003
    • (2003) Neurology , vol.60 , Issue.8 , pp. 1274-1283
    • Dworkin, R.H.1    Corbin, A.E.2    Young Jr., J.P.3
  • 48
    • 34548781289 scopus 로고    scopus 로고
    • Dose-response relationship of pregabalin in patients with generalized anxiety disorder
    • Bech P. Dose-response relationship of pregabalin in patients with generalized anxiety disorder. A pooled analysis of four placebo-controlled trials. Pharmacopsychiatry 40(4), 163-168 (2007
    • (2007) A Pooled Analysis of Four Placebo-controlled Trials. Pharmacopsychiatry , vol.40 , Issue.4 , pp. 163-168
    • Bech, P.1
  • 49
    • 0038722338 scopus 로고    scopus 로고
    • A randomized, double-blind, placebocontrolled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder
    • Feltner DE, Crockatt JG, Dubovsky SJ et al. A randomized, double-blind, placebocontrolled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder. J. Clin. Psychopharmacol. 23(3), 240-249 (2003
    • (2003) J. Clin. Psychopharmacol , vol.23 , Issue.3 , pp. 240-249
    • Feltner, D.E.1    Crockatt, J.G.2    Dubovsky, S.J.3
  • 50
    • 33745373542 scopus 로고    scopus 로고
    • Efficacy and safety of pregabalin in the treatment of generalized anxiety disorder: A 6-week, multicenter, randomized, double-blind, placebocontrolled comparison of pregabalin and venlafaxine
    • Montgomery SA, Tobias K, Zornberg GL, Kasper S, Pande AC. Efficacy and safety of pregabalin in the treatment of generalized anxiety disorder: A 6-week, multicenter, randomized, double-blind, placebocontrolled comparison of pregabalin and venlafaxine. J. Clin. Psychiatry 67(5), 771-782 (2006
    • (2006) J. Clin. Psychiatry , vol.67 , Issue.5 , pp. 771-782
    • Montgomery, S.A.1    Tobias, K.2    Zornberg, G.L.3    Kasper, S.4    Pande, A.C.5
  • 51
    • 63849233377 scopus 로고    scopus 로고
    • Efficacy of pregabalin and venlafaxine-XR in generalized anxiety disorder: Results of a double-blind, placebo-controlled 8-week trial
    • Kasper S, Herman B, Nivoli G et al. Efficacy of pregabalin and venlafaxine-XR in generalized anxiety disorder: Results of a double-blind, placebo-controlled 8-week trial. Int. Clin. Psychopharmacol. 24(2), 87-96 (2009
    • (2009) Int. Clin. Psychopharmacol , vol.24 , Issue.2 , pp. 87-96
    • Kasper, S.1    Herman, B.2    Nivoli, G.3
  • 53
    • 80051785794 scopus 로고    scopus 로고
    • Efficacy of pregabalin in preventing relapse in patients with generalized social anxiety disorder: Results of a double-blind, placebo-controlled 26-week study
    • Greist JH, Liu-Dumaw M, Schweizer E, Feltner D. Efficacy of pregabalin in preventing relapse in patients with generalized social anxiety disorder: Results of a double-blind, placebo-controlled 26-week study. Int. Clin. Psychopharmacol. 26(5), 243-251 (2011
    • (2011) Int. Clin. Psychopharmacol , vol.26 , Issue.5 , pp. 243-251
    • Greist, J.H.1    Liu-Dumaw, M.2    Schweizer, E.3    Feltner, D.4
  • 54
    • 24344448269 scopus 로고    scopus 로고
    • Pregabalin for treatment of generalized anxiety disorder: A 4-week, multicenter, double-blind, placebo-controlled trial of pregabalin and alprazolam
    • Rickels K, Pollack MH, Feltner DE et al. Pregabalin for treatment of generalized anxiety disorder: A 4-week, multicenter, double-blind, placebo-controlled trial of pregabalin and alprazolam. Arch. Gen. Psychiatry 62(9), 1022-1030 (2005
    • (2005) Arch. Gen. Psychiatry , vol.62 , Issue.9 , pp. 1022-1030
    • Rickels, K.1    Pollack, M.H.2    Feltner, D.E.3
  • 55
    • 0037364633 scopus 로고    scopus 로고
    • Pregabalin in generalized anxiety disorder: A placebo-controlled trial
    • Pande AC, Crockatt JG, Feltner DE et al. Pregabalin in generalized anxiety disorder: A placebo-controlled trial. Am. J. Psychiatry 160(3), 533-540 (2003
    • (2003) Am. J. Psychiatry , vol.160 , Issue.3 , pp. 533-540
    • Pande, A.C.1    Crockatt, J.G.2    Feltner, D.E.3
  • 56
    • 79952795159 scopus 로고    scopus 로고
    • Efficacy of drug treatments for generalised anxiety disorder: Systematic review and meta-analysis
    • Baldwin D, Woods R, Lawson R, Taylor D. Efficacy of drug treatments for generalised anxiety disorder: Systematic review and meta-analysis. BMJ 342, d1199 (2011
    • (2011) BMJ , vol.342 , pp. 1199
    • Baldwin, D.1    Woods, R.2    Lawson, R.3    Taylor, D.4
  • 57
    • 42749093852 scopus 로고    scopus 로고
    • Efficacy of pregabalin in depressive symptoms associated with generalized anxiety disorder: A pooled analysis of 6 studies
    • Stein DJ, Baldwin DS, Baldinetti F, Mandel F. Efficacy of pregabalin in depressive symptoms associated with generalized anxiety disorder: A pooled analysis of 6 studies. Eur. Neuropsychopharmacol. 18(6), 422-430 (2008
    • (2008) Eur. Neuropsychopharmacol , vol.18 , Issue.6 , pp. 422-430
    • Stein, D.J.1    Baldwin, D.S.2    Baldinetti, F.3    Mandel, F.4
  • 58
    • 77949654119 scopus 로고    scopus 로고
    • Comparative efficacy of pregabalin and benzodiazepines in treating the psychic and somatic symptoms of generalized anxiety disorder
    • Lydiard RB, Rickels K, Herman B, Feltner DE. Comparative efficacy of pregabalin and benzodiazepines in treating the psychic and somatic symptoms of generalized anxiety disorder. Int. J. Neuropsychopharmacol. 13(2), 229-241 (2010
    • (2010) Int. J. Neuropsychopharmacol , vol.13 , Issue.2 , pp. 229-241
    • Lydiard, R.B.1    Rickels, K.2    Herman, B.3    Feltner, D.E.4
  • 59
    • 84859268366 scopus 로고    scopus 로고
    • Adjunctive therapy with pregabalin in generalized anxiety disorder patients with partial response to SSRI or SNRI treatment
    • Rickels K, Shiovitz TM, Ramey TS, Weaver JJ, Knapp LE, Miceli JJ. Adjunctive therapy with pregabalin in generalized anxiety disorder patients with partial response to SSRI or SNRI treatment. Int. Clin. Psychopharmacol. 27(3), 142-150 (2012
    • (2012) Int. Clin. Psychopharmacol , vol.27 , Issue.3 , pp. 142-150
    • Rickels, K.1    Shiovitz, T.M.2    Ramey, T.S.3    Weaver, J.J.4    Knapp, L.E.5    Miceli, J.J.6
  • 60
    • 84862575407 scopus 로고    scopus 로고
    • Characterizing and understanding body weight patterns in patients treated with pregabalin
    • Cabrera J, Emir B, Dills D, Murphy TK, Whalen E, Clair A. Characterizing and understanding body weight patterns in patients treated with pregabalin. Curr. Med. Res. Opin. 28(6), 1027-1037 (2012
    • (2012) Curr. Med. Res. Opin , vol.28 , Issue.6 , pp. 1027-1037
    • Cabrera, J.1    Emir, B.2    Dills, D.3    Murphy, T.K.4    Whalen, E.5    Clair, A.6
  • 61
    • 84866105435 scopus 로고    scopus 로고
    • Pregabalin treatment for peripheral neuropathic pain: A review of safety data from randomized controlled trials conducted in Japan and in the west
    • Ogawa S, Satoh J, Arakawa A, Yoshiyama T, Suzuki M. Pregabalin treatment for peripheral neuropathic pain: A review of safety data from randomized controlled trials conducted in Japan and in the west. Drug Saf. 35(10), 793-806 (2012
    • (2012) Drug Saf , vol.35 , Issue.10 , pp. 793-806
    • Ogawa, S.1    Satoh, J.2    Arakawa, A.3    Yoshiyama, T.4    Suzuki, M.5
  • 62
    • 42949169541 scopus 로고    scopus 로고
    • Bodyweight gain under pregabalin therapy in epilepsy: Mitigation by counseling patients?
    • Hoppe C, Rademacher M, Hoffmann JM, Schmidt D, Elger CE. Bodyweight gain under pregabalin therapy in epilepsy: Mitigation by counseling patients? Seizure 17(4), 327-332 (2008
    • (2008) Seizure , vol.17 , Issue.4 , pp. 327-332
    • Hoppe, C.1    Rademacher, M.2    Hoffmann, J.M.3    Schmidt, D.4    Elger, C.E.5
  • 63
    • 84864118559 scopus 로고    scopus 로고
    • Mode of action associated with development of hemangiosarcoma in mice given pregabalin and assessment of human relevance
    • Criswell KA, Cook JC, Wojcinski Z et al. Mode of action associated with development of hemangiosarcoma in mice given pregabalin and assessment of human relevance. Toxicol. Sci. 128(1), 57-71 (2012
    • (2012) Toxicol. Sci , vol.128 , Issue.1 , pp. 57-71
    • Criswell, K.A.1    Cook, J.C.2    Wojcinski, Z.3
  • 64
    • 15444363963 scopus 로고    scopus 로고
    • Efficacy of pregabalin in the treatment of generalized anxiety disorder: Double-blind, placebo-controlled comparison of BID versus TID dosing
    • Pohl RB, Feltner DE, Fieve RR, Pande AC. Efficacy of pregabalin in the treatment of generalized anxiety disorder: Double-blind, placebo-controlled comparison of BID versus TID dosing. J. Clin. Psychopharmacol. 25(2), 151-158 (2005
    • (2005) J. Clin. Psychopharmacol , vol.25 , Issue.2 , pp. 151-158
    • Pohl, R.B.1    Feltner, D.E.2    Fieve, R.R.3    Pande, A.C.4
  • 65
    • 79952279452 scopus 로고    scopus 로고
    • Potential for pregabalin abuse or diversion after past drug-seeking behavior
    • Filipetto FA, Zipp CP, Coren JS. Potential for pregabalin abuse or diversion after past drug-seeking behavior. J. Am. Osteopath. Assoc. 110(10), 605-607 (2010
    • (2010) J. Am. Osteopath. Assoc , vol.110 , Issue.10 , pp. 605-607
    • Filipetto, F.A.1    Zipp, C.P.2    Coren, J.S.3
  • 66
    • 77954230483 scopus 로고    scopus 로고
    • Pregabalin abuse, dependence, and withdrawal: A case report
    • Grosshans M, Mutschler J, Hermann D et al. Pregabalin abuse, dependence, and withdrawal: A case report. Am. J. Psychiatry 167(7), 869 (2010
    • (2010) Am. J. Psychiatry , vol.167 , Issue.7 , pp. 869
    • Grosshans, M.1    Mutschler, J.2    Hermann, D.3
  • 67
    • 77956189824 scopus 로고    scopus 로고
    • A signal for an abuse liability for pregabalin-results from the Swedish spontaneous adverse drug reaction reporting system
    • Schwan S, Sundstrom A, Stjernberg E, Hallberg E, Hallberg P. A signal for an abuse liability for pregabalin-results from the Swedish spontaneous adverse drug reaction reporting system. Eur. J. Clin. Pharmacol. 66(9), 947-953 (2010
    • (2010) Eur. J. Clin. Pharmacol , vol.66 , Issue.9 , pp. 947-953
    • Schwan, S.1    Sundstrom, A.2    Stjernberg, E.3    Hallberg, E.4    Hallberg, P.5
  • 68
    • 78650866015 scopus 로고    scopus 로고
    • Is there a recreational misuse potential for pregabalin? Analysis of anecdotal online reports in comparison with related gabapentin and clonazepam data
    • Schifano F, D'Offizi S, Piccione M et al. Is there a recreational misuse potential for pregabalin? Analysis of anecdotal online reports in comparison with related gabapentin and clonazepam data. Psychother. Psychosom. 80(2), 118-122 (2011
    • (2011) Psychother. Psychosom , vol.80 , Issue.2 , pp. 118-122
    • Schifano, F.1    D'Offizi, S.2    Piccione, M.3
  • 70
    • 84876268516 scopus 로고    scopus 로고
    • Anxiety disorders and drug dependence: Evidence on sequence and specificity among adults
    • Goodwin RD, Stein DJ. Anxiety disorders and drug dependence: Evidence on sequence and specificity among adults. Psychiatry Clin. Neurosci. 67(3), 167-173 (2013
    • (2013) Psychiatry Clin. Neurosci , vol.67 , Issue.3 , pp. 167-173
    • Goodwin, R.D.1    Stein, D.J.2
  • 71
    • 38949154090 scopus 로고    scopus 로고
    • Human and economic burden of generalized anxiety disorder
    • Hoffman DL, Dukes EM, Wittchen HU. Human and economic burden of generalized anxiety disorder. Depress. Anxiety 25(1), 72-90 (2008
    • (2008) Depress. Anxiety , vol.25 , Issue.1 , pp. 72-90
    • Hoffman, D.L.1    Dukes, E.M.2    Wittchen, H.U.3
  • 72
    • 84877032548 scopus 로고    scopus 로고
    • A cost-utility analysis of pregabalin versus venlafaxine XR in the treatment of generalized anxiety disorder in Portugal
    • Silva ML, Silva MN, Ines M. A cost-utility analysis of pregabalin versus venlafaxine XR in the treatment of generalized anxiety disorder in Portugal. Cost Eff. Resour. Alloc. 11(1), 8 (2013
    • (2013) Cost Eff. Resour. Alloc , vol.11 , Issue.1-8
    • Silva, M.L.1    Silva, M.N.2    Ines, M.3
  • 73
    • 76649091257 scopus 로고    scopus 로고
    • Costeffectiveness of pregabalin versus venlafaxine in the treatment of generalized anxiety disorder: Faindings from a Spanish perspective
    • Vera-Llonch M, Dukes E, Rejas J, Sofrygin O, Mychaskiw M, Oster G. Costeffectiveness of pregabalin versus venlafaxine in the treatment of generalized anxiety disorder: Faindings from a Spanish perspective. Eur. J. Health Econ. 11(1), 35-44 (2010
    • (2010) Eur. J. Health Econ , vol.11 , Issue.1 , pp. 35-44
    • Vera-Llonch, M.1    Dukes, E.2    Rejas, J.3    Sofrygin, O.4    Mychaskiw, M.5    Oster, G.6
  • 74
    • 84930484524 scopus 로고    scopus 로고
    • Pregabalin versus SSRIs and SNRIs in benzodiazepine-refractory outpatients with generalized anxiety disorder: A post hoc cost-effectiveness analysis in usual medical practice in Spain
    • De Salas-Cansado M, Olivares JM, Alvarez E, Carrasco JL, Barrueta A, Rejas J. Pregabalin versus SSRIs and SNRIs in benzodiazepine-refractory outpatients with generalized anxiety disorder: A post hoc cost-effectiveness analysis in usual medical practice in Spain. Clinicoecon. Outcomes Res. 4, 157-168 (2012
    • (2012) Clinicoecon. Outcomes Res , vol.4 , pp. 157-168
    • De Salas-Cansado, M.1    Olivares, J.M.2    Alvarez, E.3    Carrasco, J.L.4    Barrueta, A.5    Rejas, J.6
  • 75
    • 84878620150 scopus 로고    scopus 로고
    • Modelling the cost-effectiveness of pregabalin versus usual care in daily practice in the treatment of refractory generalised anxiety disorder in Spain
    • De Salas-Cansado M, Alvarez E, Olivares JM, Carrasco JL, Ferro MB, Rejas J. Modelling the cost-effectiveness of pregabalin versus usual care in daily practice in the treatment of refractory generalised anxiety disorder in Spain. Soc. Psychiatry Psychiatr. Epidemiol. 48(6), 985-996 (2013
    • (2013) Soc. Psychiatry Psychiatr. Epidemiol , vol.48 , Issue.6 , pp. 985-996
    • De Salas-Cansado, M.1    Alvarez, E.2    Olivares, J.M.3    Carrasco, J.L.4    Ferro, M.B.5    Rejas, J.6
  • 76
    • 33645099460 scopus 로고    scopus 로고
    • Medication augmentation after the failure of SSRIs for depression
    • Trivedi MH, Fava M, Wisniewski SR et al. Medication augmentation after the failure of SSRIs for depression. N. Engl. J. Med. 354(12), 1243-1252 (2006
    • (2006) N. Engl. J. Med , vol.354 , Issue.12 , pp. 1243-1252
    • Trivedi, M.H.1    Fava, M.2    Wisniewski, S.R.3
  • 77
    • 55949104118 scopus 로고    scopus 로고
    • Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder
    • Montgomery S, Chatamra K, Pauer L, Whalen E, Baldinetti F. Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder. Br. J. Psychiatry 193(5), 389-394 (2008
    • (2008) Br. J. Psychiatry , vol.193 , Issue.5 , pp. 389-394
    • Montgomery, S.1    Chatamra, K.2    Pauer, L.3    Whalen, E.4    Baldinetti, F.5


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