Strain differences influence timing and magnitude of both acute and late inflammatory reactions after intratracheal instillation of an alkylating agent in rats

Journal of Applied Toxicology

Volumn 34, Issue 3, 2014, Pages 272-280

  Gustafsson, Åsa ^a,b   Svensson Elfsmark, Linda ^a   Lorentzen, Johnny C ^c   Bucht, Anders ^a,b  

^a SWEDISH DEFENCE RESEARCH AGENCY   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Genetic; Inflammation; Melphalan; Mustard gas; Pulmonary fibrosis

Indexed keywords

CHLORMETHINE; GAMMA INTERFERON; MELPHALAN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DARK AGOUTI RAT; DENDRITIC CELL; DOSE RESPONSE; FEMALE; FISCHER 344 RAT; HELPER CELL; INBRED RAT STRAIN; LEUKOCYTE; LEWIS RAT; LUNG EDEMA; LUNG INFILTRATE; LYMPHOCYTE COUNT; MACROPHAGE; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PIEBALD VIROL GLAXO RAT; PNEUMONIA; PRIORITY JOURNAL; RAT; STRAIN DIFFERENCE; SYSTEMATIC REVIEW; T LYMPHOCYTE SUBPOPULATION;

BRASSICACEAE; RATTUS;

GENETIC; INFLAMMATION; MELPHALAN; MUSTARD GAS; PULMONARY FIBROSIS;

ACUTE DISEASE; ANIMALS; CHEMICAL WARFARE AGENTS; DISEASE MODELS, ANIMAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; INSTILLATION, DRUG; INTUBATION, INTRATRACHEAL; KILLER CELLS, NATURAL; LYMPHOCYTE COUNT; MELPHALAN; NEUTROPHIL INFILTRATION; PNEUMONIA; PULMONARY FIBROSIS; RATS; RATS, INBRED STRAINS; SEVERITY OF ILLNESS INDEX; SPECIES SPECIFICITY; T-LYMPHOCYTES, HELPER-INDUCER; TIME FACTORS;

EID: 84893009359     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2878     Document Type: Article

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