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Volumn 95, Issue 1, 2014, Pages 64-77

The effects of di(2-ethylhexyl)phthalate on rat liver in relation to selenium status

Author keywords

Antioxidant enzymes; Di(ethylhexyl)phthalate; Liver; Oxidative stress; Selenium deficiency; Selenium supplementation

Indexed keywords

AMINOTRANSFERASE; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE TRANSFERASE; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; SELENIUM; SUPEROXIDE DISMUTASE; THIOREDOXIN REDUCTASE;

EID: 84893007105     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/iep.12059     Document Type: Article
Times cited : (54)

References (79)
  • 1
    • 0000024078 scopus 로고
    • Catalase
    • In:New York: Academic press 3:
    • Aebi H. (1974) Catalase. In: Methods of Enzymatic Analysis, 2nd edn (ed. HU Bergmeyer), New York: Academic press 3: 673.
    • (1974) Methods of Enzymatic Analysis , pp. 673
    • Aebi, H.1
  • 2
    • 0019740345 scopus 로고
    • Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples
    • Akerboom T.P. & Sies H. (1981) Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples. Meth. Enzymol. 77, 373-382.
    • (1981) Meth. Enzymol. , vol.77 , pp. 373-382
    • Akerboom, T.P.1    Sies, H.2
  • 3
    • 1642433172 scopus 로고    scopus 로고
    • Phthalate induced Leydig cell hyperplasia is associated with multiple endocrine disturbances
    • Akingbemi B.T., Ge R., Klinefelter G.R., Zikrin B.R., Hardy M.P. (2004) Phthalate induced Leydig cell hyperplasia is associated with multiple endocrine disturbances. Proc. Natl Acad. Sci. USA 101, 775-780.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 775-780
    • Akingbemi, B.T.1    Ge, R.2    Klinefelter, G.R.3    Zikrin, B.R.4    Hardy, M.P.5
  • 4
    • 0031773474 scopus 로고    scopus 로고
    • Preparation and assay of mammalian thioredoxin and thioredoxin reductase
    • Arnér E.S., Zhong L., Holmgren A. (1999) Preparation and assay of mammalian thioredoxin and thioredoxin reductase. Methods Enzymol. 300, 226-239.
    • (1999) Methods Enzymol. , vol.300 , pp. 226-239
    • Arnér, E.S.1    Zhong, L.2    Holmgren, A.3
  • 5
    • 67349120863 scopus 로고    scopus 로고
    • Focus on mammalian thioredoxin reductases-important selenoproteins with versatile functions
    • Arnér E.S. (2009) Focus on mammalian thioredoxin reductases-important selenoproteins with versatile functions. Biochim. Biophys. Acta 1790, 495-526.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 495-526
    • Arnér, E.S.1
  • 6
    • 33751178410 scopus 로고    scopus 로고
    • The thioredoxin system in cancer
    • Arnér E.S. & Holmgren A. (2006) The thioredoxin system in cancer. Semin. Cancer Biol. 16, 420-426.
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 420-426
    • Arnér, E.S.1    Holmgren, A.2
  • 7
    • 70350291251 scopus 로고    scopus 로고
    • Vitamin C and resveratrol supplementation to rat dams treated with di(2-ethylhexyl)phthalate: impact on reproductive and oxidative stress end points in male offspring
    • Botelho G.G., Bufalo A.C., Boareto A.C. et al. (2009) Vitamin C and resveratrol supplementation to rat dams treated with di(2-ethylhexyl)phthalate: impact on reproductive and oxidative stress end points in male offspring. Arch. Environ. Contam. Toxicol. 57, 785-793.
    • (2009) Arch. Environ. Contam. Toxicol. , vol.57 , pp. 785-793
    • Botelho, G.G.1    Bufalo, A.C.2    Boareto, A.C.3
  • 8
    • 0025963166 scopus 로고
    • Selenium in forage crops and cancer mortality in US counties
    • Clark L.C., Cantor K.P., Allaway W.H. (1991) Selenium in forage crops and cancer mortality in US counties. Arch. Environ. Health 46, 37-42.
    • (1991) Arch. Environ. Health , vol.46 , pp. 37-42
    • Clark, L.C.1    Cantor, K.P.2    Allaway, W.H.3
  • 9
    • 0024918679 scopus 로고
    • Possible mechanisms in hepatocarcinogenesis by the peroxisome proliferator di(2-ethylhexyl)phthalate
    • Conway J.G., Cattley R.C., Popp J.A., Butterworth B.E. (1989) Possible mechanisms in hepatocarcinogenesis by the peroxisome proliferator di(2-ethylhexyl)phthalate. Drug Metab. Rev. 21, 65-102.
    • (1989) Drug Metab. Rev. , vol.21 , pp. 65-102
    • Conway, J.G.1    Cattley, R.C.2    Popp, J.A.3    Butterworth, B.E.4
  • 11
    • 77951663321 scopus 로고    scopus 로고
    • Selenium in the prevention and treatment of hepatocellular carcinoma
    • Darvesh A.S. & Bishayee A. (2010) Selenium in the prevention and treatment of hepatocellular carcinoma. Anticancer Agents Med. Chem. 10, 338-345.
    • (2010) Anticancer Agents Med. Chem. , vol.10 , pp. 338-345
    • Darvesh, A.S.1    Bishayee, A.2
  • 13
    • 84925853579 scopus 로고    scopus 로고
    • The therapeutic applications of celery oil seed extract on the plasticizer di(2-ethylhexyl) phthalate toxicity
    • doi: 10.1177/0748233713475515
    • El-Shinnawy N.A. (2013) The therapeutic applications of celery oil seed extract on the plasticizer di(2-ethylhexyl) phthalate toxicity. Toxicol. Ind. Health. doi: 10.1177/0748233713475515 (Ahead of print).
    • (2013) Toxicol. Ind. Health
    • El-Shinnawy, N.A.1
  • 14
    • 77954511322 scopus 로고    scopus 로고
    • Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells
    • Erkekoglu P., Rachidi W., De Rosa V., Giray B., Favier A., Hincal F. (2010a) Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells. Free Radic. Biol. Med. 49, 559-566.
    • (2010) Free Radic. Biol. Med. , vol.49 , pp. 559-566
    • Erkekoglu, P.1    Rachidi, W.2    De Rosa, V.3    Giray, B.4    Favier, A.5    Hincal, F.6
  • 15
    • 77956402478 scopus 로고    scopus 로고
    • Evaluation of cytotoxicity and oxidative DNA damaging effects of di(2-ethylhexyl)-phthalate (DEHP) and mono(2-ethylhexyl)-phthalate (MEHP) on MA-10 Leydig cells and protection by selenium
    • Erkekoglu P., Rachidi W., Yuzugullu O.G. et al. (2010b) Evaluation of cytotoxicity and oxidative DNA damaging effects of di(2-ethylhexyl)-phthalate (DEHP) and mono(2-ethylhexyl)-phthalate (MEHP) on MA-10 Leydig cells and protection by selenium. Toxicol. Appl. Pharmacol. 248, 52-62.
    • (2010) Toxicol. Appl. Pharmacol. , vol.248 , pp. 52-62
    • Erkekoglu, P.1    Rachidi, W.2    Yuzugullu, O.G.3
  • 16
    • 79957636982 scopus 로고    scopus 로고
    • Reproductive toxicity of di(2-ethylhexyl) phthalate in selenium-supplemented and selenium-deficient rats
    • Erkekoglu P., Zeybek N.D., Giray B., Asan E., Arnaud J., Hincal F. (2011a) Reproductive toxicity of di(2-ethylhexyl) phthalate in selenium-supplemented and selenium-deficient rats. Drug Chem. Toxicol. 34, 379-389.
    • (2011) Drug Chem. Toxicol. , vol.34 , pp. 379-389
    • Erkekoglu, P.1    Zeybek, N.D.2    Giray, B.3    Asan, E.4    Arnaud, J.5    Hincal, F.6
  • 17
    • 84890493662 scopus 로고    scopus 로고
    • Effects of di(2-ethylhexyl)phthalate on testicular oxidant/antioxidant status in selenium-deficient and selenium-supplemented rats
    • doi: 10.1002/tox.20776
    • Erkekoglu P., Giray B., Rachidi W. et al. (2011b) Effects of di(2-ethylhexyl)phthalate on testicular oxidant/antioxidant status in selenium-deficient and selenium-supplemented rats. Environ. Toxicol. doi: 10.1002/tox.20776.
    • (2011) Environ. Toxicol.
    • Erkekoglu, P.1    Giray, B.2    Rachidi, W.3
  • 18
    • 84862259374 scopus 로고    scopus 로고
    • Di(2-ethylhexyl)phthalate-induced renal oxidative stress in rats and protective effect of selenium
    • Erkekoglu P., Giray B.K., Kizilgün M. et al. (2012a) Di(2-ethylhexyl)phthalate-induced renal oxidative stress in rats and protective effect of selenium. Toxicol. Mech. Methods 22, 415-423.
    • (2012) Toxicol. Mech. Methods , vol.22 , pp. 415-423
    • Erkekoglu, P.1    Giray, B.K.2    Kizilgün, M.3
  • 19
    • 84871277397 scopus 로고    scopus 로고
    • Thyroidal effects of di-(2-Ethylhexyl) phthalate in rats at different selenium status
    • Erkekoglu P., Giray B.K., Kizilgün M. et al. (2012b) Thyroidal effects of di-(2-Ethylhexyl) phthalate in rats at different selenium status. J. Environ. Pathol. Toxicol. Oncol. 31, 143-153.
    • (2012) J. Environ. Pathol. Toxicol. Oncol. , vol.31 , pp. 143-153
    • Erkekoglu, P.1    Giray, B.K.2    Kizilgün, M.3
  • 20
    • 84856082515 scopus 로고    scopus 로고
    • The effect of sodium selenite on liver growth and thioredoxin reductase expression in regenerative and neoplastic liver cell proliferation
    • Erkhembayar S., Mollbrink A., Eriksson L.C. (2012) The effect of sodium selenite on liver growth and thioredoxin reductase expression in regenerative and neoplastic liver cell proliferation. Biochem. Pharmacol. 83, 687-693.
    • (2012) Biochem. Pharmacol. , vol.83 , pp. 687-693
    • Erkhembayar, S.1    Mollbrink, A.2    Eriksson, L.C.3
  • 21
    • 0021288821 scopus 로고
    • Assays of glutathione peroxidase
    • Flohé L. & Günzler W.A. (1984) Assays of glutathione peroxidase. Meth. Enzymol. 105, 114-121.
    • (1984) Meth. Enzymol. , vol.105 , pp. 114-121
    • Flohé, L.1    Günzler, W.A.2
  • 22
    • 34848893570 scopus 로고    scopus 로고
    • Intake of phthalates and di(2-ethylhexyl)adipate: results of the Integrated Exposure Assessment Survey based on duplicate diet samples and biomonitoring data
    • Fromme H., Gruber L., Schlummer M. et al. (2007) Intake of phthalates and di(2-ethylhexyl)adipate: results of the Integrated Exposure Assessment Survey based on duplicate diet samples and biomonitoring data. Environ. Int. 33, 1012-1020.
    • (2007) Environ. Int. , vol.33 , pp. 1012-1020
    • Fromme, H.1    Gruber, L.2    Schlummer, M.3
  • 23
    • 0032848137 scopus 로고    scopus 로고
    • Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase
    • Ganther D.E. (1999) Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase. Carcinogenesis 20, 1657-1666.
    • (1999) Carcinogenesis , vol.20 , pp. 1657-1666
    • Ganther, D.E.1
  • 24
    • 2442528657 scopus 로고    scopus 로고
    • Changes in some hormones by low doses of di (2-ethyl hexyl) phthalate (DEHP), a commonly used plasticizer in PVC blood storage bags & medical tubing
    • Gayathri N.S., Dhanya C.R., Indu A.R., Kurup P.A. (2004) Changes in some hormones by low doses of di (2-ethyl hexyl) phthalate (DEHP), a commonly used plasticizer in PVC blood storage bags & medical tubing. Indian J. Med. Res. 119, 139-144.
    • (2004) Indian J. Med. Res. , vol.119 , pp. 139-144
    • Gayathri, N.S.1    Dhanya, C.R.2    Indu, A.R.3    Kurup, P.A.4
  • 25
    • 0036286837 scopus 로고    scopus 로고
    • Effect of peroxisome proliferators on Leydig cell peripheral-type benzodiazepine receptor gene expression, hormone-stimulated cholesterol transport, and steroidogenesis: role of the peroxisome proliferator-activator receptor alpha
    • Gazouli M., Yao Z.X., Boujrad N., Corton J.C., Culty M., Papadopoulos V. (2002) Effect of peroxisome proliferators on Leydig cell peripheral-type benzodiazepine receptor gene expression, hormone-stimulated cholesterol transport, and steroidogenesis: role of the peroxisome proliferator-activator receptor alpha. Endocrinology 143, 2571-2583.
    • (2002) Endocrinology , vol.143 , pp. 2571-2583
    • Gazouli, M.1    Yao, Z.X.2    Boujrad, N.3    Corton, J.C.4    Culty, M.5    Papadopoulos, V.6
  • 26
    • 2042465021 scopus 로고    scopus 로고
    • Oxidant/antioxidant status in relation to thyroid hormone metabolism in selenium- and/or iodine-deficient rats
    • Giray B., Riondel J., Richard M.J., Favier A., Hincal F. (2004) Oxidant/antioxidant status in relation to thyroid hormone metabolism in selenium- and/or iodine-deficient rats. J. Trace Elem. Exp. Med. 17, 109-121.
    • (2004) J. Trace Elem. Exp. Med. , vol.17 , pp. 109-121
    • Giray, B.1    Riondel, J.2    Richard, M.J.3    Favier, A.4    Hincal, F.5
  • 28
    • 0016275313 scopus 로고
    • Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
    • Habig W.H., Pabst M.J., Jakoby W.B. (1974) Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249, 7130-7139.
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 29
    • 0016170551 scopus 로고
    • Effect of dietary selenium on erythrocyte and liver glutathione peroxidase in the rat
    • Hafeman D.G., Sunde R.A., Hoekstra W.G. (1974) Effect of dietary selenium on erythrocyte and liver glutathione peroxidase in the rat. J. Nutr. 104, 580-587.
    • (1974) J. Nutr. , vol.104 , pp. 580-587
    • Hafeman, D.G.1    Sunde, R.A.2    Hoekstra, W.G.3
  • 30
    • 0034065023 scopus 로고    scopus 로고
    • Species differences in response to diethylhexylphthalate: suppression of apoptosis, induction of DNA synthesis and peroxisome proliferator activated receptor alpha-mediated gene expression
    • Hasmall S.C., James N.H., Macdonald N., Soames A.R., Roberts R.A. (2000) Species differences in response to diethylhexylphthalate: suppression of apoptosis, induction of DNA synthesis and peroxisome proliferator activated receptor alpha-mediated gene expression. Arch. Toxicol. 74, 85-91.
    • (2000) Arch. Toxicol. , vol.74 , pp. 85-91
    • Hasmall, S.C.1    James, N.H.2    Macdonald, N.3    Soames, A.R.4    Roberts, R.A.5
  • 32
    • 0142250899 scopus 로고    scopus 로고
    • Acquired tolerance of hepatocellular carcinoma cells to selenium deficiency: a selective survival mechanism?
    • Irmak M.B., Ince G., Ozturk M., Cetin-Atalay R. (2003) Acquired tolerance of hepatocellular carcinoma cells to selenium deficiency: a selective survival mechanism? Cancer Res. 63, 6707-6715.
    • (2003) Cancer Res. , vol.63 , pp. 6707-6715
    • Irmak, M.B.1    Ince, G.2    Ozturk, M.3    Cetin-Atalay, R.4
  • 34
    • 69949178378 scopus 로고    scopus 로고
    • Association between GPx1 Pro198Leu polymorphism, GPx1 activity and plasma selenium concentration in humans
    • Jablonska E., Gromadzinska J., Reszka E. et al. (2009) Association between GPx1 Pro198Leu polymorphism, GPx1 activity and plasma selenium concentration in humans. Eur. J. Nutr. 48, 383-386.
    • (2009) Eur. J. Nutr. , vol.48 , pp. 383-386
    • Jablonska, E.1    Gromadzinska, J.2    Reszka, E.3
  • 35
    • 0032435561 scopus 로고    scopus 로고
    • Suppression of hepatocyte apoptosis and induction of DNA synthesis by the rat and mouse hepatocarcinogen diethylhexylphlathate (DEHP) and the mouse hepatocarcinogen 1,4-dichlorobenzene (DCB)
    • James N.H., Soames A.R., Roberts R.A. (1998) Suppression of hepatocyte apoptosis and induction of DNA synthesis by the rat and mouse hepatocarcinogen diethylhexylphlathate (DEHP) and the mouse hepatocarcinogen 1, 4-dichlorobenzene (DCB). Arch. Toxicol. 72, 784-790.
    • (1998) Arch. Toxicol. , vol.72 , pp. 784-790
    • James, N.H.1    Soames, A.R.2    Roberts, R.A.3
  • 36
    • 0346156024 scopus 로고    scopus 로고
    • PPARalpha agonist-induced rodent tumors: modes of action and human relevance
    • Klaunig J.E., Babich M.A., Baetcke K.P. et al. (2003) PPARalpha agonist-induced rodent tumors: modes of action and human relevance. Crit. Rev. Toxicol. 33, 655-780.
    • (2003) Crit. Rev. Toxicol. , vol.33 , pp. 655-780
    • Klaunig, J.E.1    Babich, M.A.2    Baetcke, K.P.3
  • 37
    • 0022249191 scopus 로고
    • Comparative chronic toxicities and carcinogenic potentials of 2-ethylhexyl-containing compounds in rats and mice
    • Kluwe W.M., Huff J.E., Matthews H.B., Irwin R., Haseman J.K. (1985) Comparative chronic toxicities and carcinogenic potentials of 2-ethylhexyl-containing compounds in rats and mice. Carcinogenesis 6, 1577-1583.
    • (1985) Carcinogenesis , vol.6 , pp. 1577-1583
    • Kluwe, W.M.1    Huff, J.E.2    Matthews, H.B.3    Irwin, R.4    Haseman, J.K.5
  • 38
    • 25644445313 scopus 로고    scopus 로고
    • Monitoring phthalate exposure in humans
    • Latini G. (2005) Monitoring phthalate exposure in humans. Clin. Chim. Acta 361, 20-29.
    • (2005) Clin. Chim. Acta , vol.361 , pp. 20-29
    • Latini, G.1
  • 40
    • 0025142673 scopus 로고
    • Phospholipid hydroperoxide glutathione peroxidase
    • Maiorino M., Gregolin C., Ursini F. (1990) Phospholipid hydroperoxide glutathione peroxidase. Meth. Enzymol. 186, 448-457.
    • (1990) Meth. Enzymol. , vol.186 , pp. 448-457
    • Maiorino, M.1    Gregolin, C.2    Ursini, F.3
  • 41
    • 0016272750 scopus 로고
    • Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund S., Marklund G. (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 47, 469-474.
    • (1974) Eur. J. Biochem. , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 42
    • 28144449739 scopus 로고    scopus 로고
    • Pathophysiological basis for antioxidant therapy in chronic liver disease
    • Medina J. & Moreno-Otero R. (2005) Pathophysiological basis for antioxidant therapy in chronic liver disease. Drugs 65, 2445-2461.
    • (2005) Drugs , vol.65 , pp. 2445-2461
    • Medina, J.1    Moreno-Otero, R.2
  • 43
    • 0035325333 scopus 로고    scopus 로고
    • Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)?
    • Melnick R.L. (2001) Is peroxisome proliferation an obligatory precursor step in the carcinogenicity of di(2-ethylhexyl)phthalate (DEHP)? Environ. Health Perspect. 109, 437-442.
    • (2001) Environ. Health Perspect. , vol.109 , pp. 437-442
    • Melnick, R.L.1
  • 44
    • 0017861747 scopus 로고
    • The hepatic effects of hypolipidemic drugs (clofibrate, nafenopin, tibric acid, and Wy-14,643) on hepatic peroxisomes and peroxisome-associated enzymes
    • Moody D.E. & Reddy J.K. (1978) The hepatic effects of hypolipidemic drugs (clofibrate, nafenopin, tibric acid, and Wy-14, 643) on hepatic peroxisomes and peroxisome-associated enzymes. Am. J. Pathol. 90, 435-446.
    • (1978) Am. J. Pathol. , vol.90 , pp. 435-446
    • Moody, D.E.1    Reddy, J.K.2
  • 45
    • 0026100678 scopus 로고
    • Peroxisome proliferation and nongenotoxic carcinogenesis: commentary on a symposium
    • Moody D.E., Reddy J.K., Lake B.G., Popp J.A., Reese D.H. (1991) Peroxisome proliferation and nongenotoxic carcinogenesis: commentary on a symposium. Fundam. Appl. Toxicol. 16, 233-248.
    • (1991) Fundam. Appl. Toxicol. , vol.16 , pp. 233-248
    • Moody, D.E.1    Reddy, J.K.2    Lake, B.G.3    Popp, J.A.4    Reese, D.H.5
  • 46
    • 0018956788 scopus 로고
    • Effect of di-2-ethylhexyl phthalate (DEHP)on glycogen metabolism in rat liver
    • Mushtaq M., Srivastava S.P., Seth P.K. (1980) Effect of di-2-ethylhexyl phthalate (DEHP)on glycogen metabolism in rat liver. Toxicology 16, 153-161.
    • (1980) Toxicology , vol.16 , pp. 153-161
    • Mushtaq, M.1    Srivastava, S.P.2    Seth, P.K.3
  • 47
    • 0034652113 scopus 로고    scopus 로고
    • Thioredoxin reductase
    • Mustacich D. & Powis G. (2000) Thioredoxin reductase. Biochem. J. 346, 1-8.
    • (2000) Biochem. J. , vol.346 , pp. 1-8
    • Mustacich, D.1    Powis, G.2
  • 48
    • 0003721552 scopus 로고
    • National Research Council (NRC)Washington, DC: National Academy Press.
    • National Research Council (NRC) (1995) Nutrient Requirements of Laboratory Animals. 4th revised edn. Washington, DC: National Academy Press.
    • (1995) Nutrient Requirements of Laboratory Animals
  • 49
    • 0033834255 scopus 로고    scopus 로고
    • Role of reactive oxygen species in the regulation of physiological functions
    • Nose K. (2000) Role of reactive oxygen species in the regulation of physiological functions. Biol. Pharm. Bull. 23, 897-903.
    • (2000) Biol. Pharm. Bull. , vol.23 , pp. 897-903
    • Nose, K.1
  • 50
    • 0034235775 scopus 로고    scopus 로고
    • Localization of antioxidant enzymes and oxidative damage products in normal and malignant prostate epithelium
    • Oberley T.D., Zhong W., Szweda L.I., Oberley L.W. (2000) Localization of antioxidant enzymes and oxidative damage products in normal and malignant prostate epithelium. Prostate 44, 144-155.
    • (2000) Prostate , vol.44 , pp. 144-155
    • Oberley, T.D.1    Zhong, W.2    Szweda, L.I.3    Oberley, L.W.4
  • 51
    • 13144266680 scopus 로고    scopus 로고
    • Role of oxidative stress in peroxisome proliferator-mediated carcinogenesis
    • O'Brien M.L., Spear B.T., Glauert H.P. (2005) Role of oxidative stress in peroxisome proliferator-mediated carcinogenesis. Crit. Rev. Toxicol. 35, 61-88.
    • (2005) Crit. Rev. Toxicol. , vol.35 , pp. 61-88
    • O'Brien, M.L.1    Spear, B.T.2    Glauert, H.P.3
  • 52
    • 0035068679 scopus 로고    scopus 로고
    • Effects of peroxisome proliferators on antioxidant enzymes and antioxidant vitamins in rats and hamsters
    • O'Brien M.L., Twaroski T.P., Cunningham M.L., Glauert H.P. & Spear B.T. (2001) Effects of peroxisome proliferators on antioxidant enzymes and antioxidant vitamins in rats and hamsters. Toxicol Sci. 60, 271-278.
    • (2001) Toxicol Sci. , vol.60 , pp. 271-278
    • O'Brien, M.L.1    Twaroski, T.P.2    Cunningham, M.L.3    Glauert, H.P.4    Spear, B.T.5
  • 53
    • 0026463532 scopus 로고
    • The involvement of selenium in peroxisome proliferation caused by dietary administration of clofibrate to rats
    • Olsson U., Garberg P., Lundgren B. et al. (1992) The involvement of selenium in peroxisome proliferation caused by dietary administration of clofibrate to rats. Chem. Biol. Interact. 5, 49-67.
    • (1992) Chem. Biol. Interact. , vol.5 , pp. 49-67
    • Olsson, U.1    Garberg, P.2    Lundgren, B.3
  • 54
    • 0024430314 scopus 로고
    • Oxidative DNA damage caused by persistent peroxisome proliferation: its role in hepatocarcinogenesis
    • Reddy J.K. & Rao M.S. (1989) Oxidative DNA damage caused by persistent peroxisome proliferation: its role in hepatocarcinogenesis. Mutat. Res. 214, 63-68.
    • (1989) Mutat. Res. , vol.214 , pp. 63-68
    • Reddy, J.K.1    Rao, M.S.2
  • 55
    • 0026467676 scopus 로고
    • Peroxisome proliferation and hepatocarcinogenesis
    • Reddy J.K. & Rao M.S. (1992) Peroxisome proliferation and hepatocarcinogenesis. IARC Sci. Publ. 116, 225-235.
    • (1992) IARC Sci. Publ. , vol.116 , pp. 225-235
    • Reddy, J.K.1    Rao, M.S.2
  • 56
    • 0026664078 scopus 로고
    • Malondialdehyde kit evaluated for determining plasma and lipoprotein fractions that react with thiobarbituric acid
    • Richard M.J., Portal B., Meo J., Coudray C., Hadjian A., Favier A. (1992) Malondialdehyde kit evaluated for determining plasma and lipoprotein fractions that react with thiobarbituric acid. Clin. Chem. 38, 704-709.
    • (1992) Clin. Chem. , vol.38 , pp. 704-709
    • Richard, M.J.1    Portal, B.2    Meo, J.3    Coudray, C.4    Hadjian, A.5    Favier, A.6
  • 57
    • 17344379118 scopus 로고    scopus 로고
    • Apoptosis and proliferation in nongenotoxic carcinogenesis: species differences and role of PPARalpha
    • Roberts R.A., James N.H., Hasmall S.C. et al. (2000) Apoptosis and proliferation in nongenotoxic carcinogenesis: species differences and role of PPARalpha. Toxicol. Lett. 112-113, 49-57.
    • (2000) Toxicol. Lett. , vol.112-113 , pp. 49-57
    • Roberts, R.A.1    James, N.H.2    Hasmall, S.C.3
  • 58
    • 84859137441 scopus 로고    scopus 로고
    • Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma
    • Rohr-Udilova N., Sieghart W., Eferl R. et al. (2012) Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma. Hepatology 55, 1112-1121.
    • (2012) Hepatology , vol.55 , pp. 1112-1121
    • Rohr-Udilova, N.1    Sieghart, W.2    Eferl, R.3
  • 59
    • 0034677712 scopus 로고    scopus 로고
    • Role of Kupffer cells and oxidants in signaling peroxisome proliferator induced hepatocyte proliferation
    • Rose M.L., Rusyn I., Bojes H.K., Belyea J., Cattley R.C., Thurman R.G. (2000) Role of Kupffer cells and oxidants in signaling peroxisome proliferator induced hepatocyte proliferation. Mutat. Res. 448, 179-192.
    • (2000) Mutat. Res. , vol.448 , pp. 179-192
    • Rose, M.L.1    Rusyn, I.2    Bojes, H.K.3    Belyea, J.4    Cattley, R.C.5    Thurman, R.G.6
  • 60
    • 0033753210 scopus 로고    scopus 로고
    • Novel role of oxidants in the molecular mechanism of action of peroxisome proliferators
    • Rusyn I., Rose M.L., Bojes H.K., Thurman R.G. (2000) Novel role of oxidants in the molecular mechanism of action of peroxisome proliferators. Antioxid. Redox Signal. 2, 607-621.
    • (2000) Antioxid. Redox Signal. , vol.2 , pp. 607-621
    • Rusyn, I.1    Rose, M.L.2    Bojes, H.K.3    Thurman, R.G.4
  • 61
    • 0035061472 scopus 로고    scopus 로고
    • Phthalates rapidly increase production of reactive oxygen species in vivo: role of Kupffer cells
    • Rusyn I., Kadiiska M.B., Dikalova A. et al. (2001) Phthalates rapidly increase production of reactive oxygen species in vivo: role of Kupffer cells. Mol. Pharmacol. 59, 744-750.
    • (2001) Mol. Pharmacol. , vol.59 , pp. 744-750
    • Rusyn, I.1    Kadiiska, M.B.2    Dikalova, A.3
  • 62
    • 33745204653 scopus 로고    scopus 로고
    • Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver
    • Rusyn I., Peters J.M., Cunningham M.L. (2006) Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver. Crit. Rev. Toxicol. 36, 459-479.
    • (2006) Crit. Rev. Toxicol. , vol.36 , pp. 459-479
    • Rusyn, I.1    Peters, J.M.2    Cunningham, M.L.3
  • 64
    • 33947575032 scopus 로고    scopus 로고
    • Does oxidative stress participate in the development of hepatocellular carcinoma?
    • Sasaki Y. (2006) Does oxidative stress participate in the development of hepatocellular carcinoma? J. Gastroenterol. 41, 1135-1148.
    • (2006) J. Gastroenterol. , vol.41 , pp. 1135-1148
    • Sasaki, Y.1
  • 65
    • 0242494348 scopus 로고    scopus 로고
    • Comparison of oxidative stress and changes of xenobiotic metabolizing enzymes induced by phthalates in rats
    • Seo K.W., Kim K.B., Kim Y.J., Choi J.Y., Lee K.T., Choi K.S. (2004) Comparison of oxidative stress and changes of xenobiotic metabolizing enzymes induced by phthalates in rats. Food Chem. Toxicol. 42, 107-114.
    • (2004) Food Chem. Toxicol. , vol.42 , pp. 107-114
    • Seo, K.W.1    Kim, K.B.2    Kim, Y.J.3    Choi, J.Y.4    Lee, K.T.5    Choi, K.S.6
  • 66
    • 72649102374 scopus 로고    scopus 로고
    • Protection against reactive oxygen species by selenoproteins
    • Steinbrenner H. & Sies H. (2009) Protection against reactive oxygen species by selenoproteins. Biochim. Biophys. Acta 1790, 1478-1485.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 1478-1485
    • Steinbrenner, H.1    Sies, H.2
  • 67
    • 0001848690 scopus 로고    scopus 로고
    • Chapter 8. Regulation of selenoprotein expression
    • In Hatfield D. Massachusetts: Kluwer Academic Publishers
    • Sundae R.A. (2003) Chapter 8. Regulation of selenoprotein expression. In: Selenium: Its Molecular Biology and Role in Human Health, (ed. Hatfield D), pp. 81-98. Massachusetts: Kluwer Academic Publishers.
    • (2003) Selenium: Its Molecular Biology and Role in Human Health , pp. 81-98
    • Sundae, R.A.1
  • 68
    • 0034884001 scopus 로고    scopus 로고
    • A comparative study on effect of dietary selenium and vitamin E on some antioxidant enzyme activities of liver and brain tissues
    • Turan B., Acan N.L., Ulusu N.N., Tezcan E.F. (2001) A comparative study on effect of dietary selenium and vitamin E on some antioxidant enzyme activities of liver and brain tissues. Biol. Trace Elem. Res. 81, 141-152.
    • (2001) Biol. Trace Elem. Res. , vol.81 , pp. 141-152
    • Turan, B.1    Acan, N.L.2    Ulusu, N.N.3    Tezcan, E.F.4
  • 69
    • 33751181030 scopus 로고    scopus 로고
    • On the potential of thioredoxin reductase inhibitors for cancer therapy
    • Urig S. & Becker K. (2006) On the potential of thioredoxin reductase inhibitors for cancer therapy. Semin. Cancer Biol. 16, 452-465.
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 452-465
    • Urig, S.1    Becker, K.2
  • 70
    • 0025183865 scopus 로고
    • Phospholipid hydroperoxide glutathione peroxidase in various mouse organs during selenium deficiency and repletion
    • Weitzel F., Ursini F., Wendel A. (1990) Phospholipid hydroperoxide glutathione peroxidase in various mouse organs during selenium deficiency and repletion. Biochim. Biophys. Acta 1036, 88-94.
    • (1990) Biochim. Biophys. Acta , vol.1036 , pp. 88-94
    • Weitzel, F.1    Ursini, F.2    Wendel, A.3
  • 71
    • 0346707259 scopus 로고    scopus 로고
    • Selenium and its relationship to cancer: an update
    • Whanger P.D. (2004) Selenium and its relationship to cancer: an update. Br. J. Nutr. 91, 11-28.
    • (2004) Br. J. Nutr. , vol.91 , pp. 11-28
    • Whanger, P.D.1
  • 72
    • 0035819853 scopus 로고    scopus 로고
    • Weight-of-evidence versus strength-of-evidence in toxicologic hazard identification: di(2-ethylhexyl)phthalate (DEHP)
    • Willhite C.C. (2001) Weight-of-evidence versus strength-of-evidence in toxicologic hazard identification: di(2-ethylhexyl)phthalate (DEHP). Toxicology 160, 219-226.
    • (2001) Toxicology , vol.160 , pp. 219-226
    • Willhite, C.C.1
  • 73
    • 33745453647 scopus 로고    scopus 로고
    • What are the sources of exposure to eight frequently used phthalic acid esters in Europeans?
    • Wormuth M., Scheringer M., Vollenweider M., Hungerbühler K. (2006) What are the sources of exposure to eight frequently used phthalic acid esters in Europeans? Risk Anal. 26, 803-824.
    • (2006) Risk Anal. , vol.26 , pp. 803-824
    • Wormuth, M.1    Scheringer, M.2    Vollenweider, M.3    Hungerbühler, K.4
  • 74
    • 0034678013 scopus 로고    scopus 로고
    • Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis
    • Yeldandi A.V., Rao M.S., Reddy J.K. (2000) Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis. Mutat. Res. 448, 159-177.
    • (2000) Mutat. Res. , vol.448 , pp. 159-177
    • Yeldandi, A.V.1    Rao, M.S.2    Reddy, J.K.3
  • 76
    • 0037340002 scopus 로고    scopus 로고
    • Age-dependent effects of nongenotoxic hepatocarcinogens on liver apoptosis in vivo
    • Youssef J.A., Bouziane M., Badr M.Z. (2003) Age-dependent effects of nongenotoxic hepatocarcinogens on liver apoptosis in vivo. Mech. Ageing Dev. 124, 333-340.
    • (2003) Mech. Ageing Dev. , vol.124 , pp. 333-340
    • Youssef, J.A.1    Bouziane, M.2    Badr, M.Z.3
  • 77
    • 0033567306 scopus 로고    scopus 로고
    • Plasma selenium levels and risk of hepatocellular carcinoma among men wit chronic hepatitis virus infection
    • Yu M.W., Horng I.S., Hsu K.H., Chiang Y.C., Liaw Y.F., Chen C.J. (1999) Plasma selenium levels and risk of hepatocellular carcinoma among men wit chronic hepatitis virus infection. Am. J. Epidemiol. 150, 367-374.
    • (1999) Am. J. Epidemiol. , vol.150 , pp. 367-374
    • Yu, M.W.1    Horng, I.S.2    Hsu, K.H.3    Chiang, Y.C.4    Liaw, Y.F.5    Chen, C.J.6
  • 78
    • 84863143861 scopus 로고    scopus 로고
    • Oxidative stress and redox signaling mechanisms of alcoholic liver disease: updated experimental and clinical evidence
    • Zhu H., Jia Z., Misra H., Li Y.R. (2012) Oxidative stress and redox signaling mechanisms of alcoholic liver disease: updated experimental and clinical evidence. J. Dig. Dis. 13, 133-142.
    • (2012) J. Dig. Dis. , vol.13 , pp. 133-142
    • Zhu, H.1    Jia, Z.2    Misra, H.3    Li, Y.R.4
  • 79
    • 84858703580 scopus 로고    scopus 로고
    • Selenium interactions and toxicity: a review. Selenium interactions and toxicity
    • Zwolak I. & Zaporowska H. (2012) Selenium interactions and toxicity: a review. Selenium interactions and toxicity. Cell Biol. Toxicol. 28, 31-46.
    • (2012) Cell Biol. Toxicol. , vol.28 , pp. 31-46
    • Zwolak, I.1    Zaporowska, H.2


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