-
1
-
-
0033621165
-
Amyloid diseases: Abnormal protein aggregation in neurodegeneration
-
Koo EH, Lansbury PT, Kelly JW. Amyloid diseases: abnormal protein aggregation in neurodegeneration. Proc Natl Acad Sci USA 1999;96:9989-90.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9989-9990
-
-
Koo, E.H.1
Lansbury, P.T.2
Kelly, J.W.3
-
2
-
-
77957103117
-
The fine structure of neurofibrillary tangles in Alzheimer's disease
-
Terry RD. The fine structure of neurofibrillary tangles in Alzheimer's disease. J Neuropathol Exp Neurol 1963;22:629-42.
-
(1963)
J Neuropathol Exp Neurol
, vol.22
, pp. 629-642
-
-
Terry, R.D.1
-
3
-
-
0030805991
-
Frequency of stages of Alzheimer-related lesions in different age categories
-
Braak H, Braak E. Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol Aging 1997;18:351-7.
-
(1997)
Neurobiol Aging
, vol.18
, pp. 351-357
-
-
Braak, H.1
Braak, E.2
-
4
-
-
0019972810
-
The cholinergic hypothesis of geriatric memory dysfunction
-
Bartus RT, Dean 3rd RL, Beer B, Lippa A. The cholinergic hypothesis of geriatric memory dysfunction. Science 1982;217:408-17.
-
(1982)
Science
, vol.217
, pp. 408-417
-
-
Bartus, R.T.1
Dean, R.L.2
Beer, B.3
Lippa, A.4
-
6
-
-
55849111494
-
Cholinergic system during the progression of Alzheimer's disease: Therapeutic implications
-
Mufson EJ, Counts SE, Perez SE, Ginsberg SD. Cholinergic system during the progression of Alzheimer's disease: therapeutic implications. Expert Rev Neurother 2008;8:1703-18.
-
(2008)
Expert Rev Neurother
, vol.8
, pp. 1703-1718
-
-
Mufson, E.J.1
Counts, S.E.2
Perez, S.E.3
Ginsberg, S.D.4
-
7
-
-
0042433479
-
The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: Recent challenges and their implications for novel drug development
-
Terry Jr AV, Buccafusco JJ. The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: recent challenges and their implications for novel drug development. J Pharmacol Exp Ther 2003;306:821-7.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 821-827
-
-
Terry, A.V.1
Buccafusco, J.J.2
-
8
-
-
77951874698
-
Persistent treatment with cholinesterase inhibitors and/or memantine shows clinical progression of Alzheimer disease
-
Rountree SD, Chan W, Pavlik VN, Darby EJ, Siddiqui S, Doody RS. Persistent treatment with cholinesterase inhibitors and/or memantine shows clinical progression of Alzheimer disease. Alzheimers Res Ther 2009;1:7.
-
(2009)
Alzheimers Res Ther
, vol.1
, pp. 7
-
-
Rountree, S.D.1
Chan, W.2
Pavlik, V.N.3
Darby, E.J.4
Siddiqui, S.5
Doody, R.S.6
-
9
-
-
33646057761
-
Ginseng and ion channels: Are ginsensosides, active component of Panax ginseng, differential modulator of ion channels?
-
Jeong SM, Nah SY. Ginseng and ion channels: are ginsensosides, active component of Panax ginseng, differential modulator of ion channels? J Ginseng Res 2005;29:19-26.
-
(2005)
J Ginseng Res
, vol.29
, pp. 19-26
-
-
Jeong, S.M.1
Nah, S.Y.2
-
10
-
-
0011986176
-
Effectsofginseng saponin on modulation of multidrug resistance
-
Park JD, Kim DS, Kwon HY, Son SK, Lee YH, Baek NI, Kim SI, Rhee DK. Effectsofginseng saponin on modulation of multidrug resistance. Arch Pharm Res 1996;19:213-8.
-
(1996)
Arch Pharm Res
, vol.19
, pp. 213-218
-
-
Park, J.D.1
Kim, D.S.2
Kwon, H.Y.3
Son, S.K.4
Lee, Y.H.5
Baek, N.I.6
Kim, S.I.7
Rhee, D.K.8
-
11
-
-
0035869723
-
Ginsenoside Rb1 and Rg1 improve spatial learning and increase hippocampal synaptophysin level in mice
-
Mook JI, Hong HS, Boo JH, Lee KH, Yun SH, Cheong MY, Joo I, Huh K, Jung MW. Ginsenoside Rb1 and Rg1 improve spatial learning and increase hippocampal synaptophysin level in mice. J Neurosci Res 2001;63:509-15.
-
(2001)
J Neurosci Res
, vol.63
, pp. 509-515
-
-
Mook, J.I.1
Hong, H.S.2
Boo, J.H.3
Lee, K.H.4
Yun, S.H.5
Cheong, M.Y.6
Joo, I.7
Huh, K.8
Jung, M.W.9
-
12
-
-
0001780741
-
Effects of ginsenoside Rb1 and ginsenoside Rg1 on learning and memory
-
Shibata S, Ohtsuka Y, Saito H, editors, Tokyo: Hirokawa Publishing
-
Saito H. Effects of ginsenoside Rb1 and ginsenoside Rg1 on learning and memory. In: Shibata S, Ohtsuka Y, Saito H, editors. Recent advances in ginseng study. Tokyo: Hirokawa Publishing; 1990. p. 99.
-
(1990)
Recent Advances In Ginseng Study
, pp. 99
-
-
Saito, H.1
-
13
-
-
0028803581
-
Effects of ginsenosides on impaired performance induced in the rat by scopolamine in a radial-arm maze
-
Yamaguchi Y, Haruta K, Kobayashi H. Effects of ginsenosides on impaired performance induced in the rat by scopolamine in a radial-arm maze. Psychoneuroendocrinology 1995;20:645-53.
-
(1995)
Psychoneuroendocrinology
, vol.20
, pp. 645-653
-
-
Yamaguchi, Y.1
Haruta, K.2
Kobayashi, H.3
-
14
-
-
1942420868
-
Ab(25-35)- induced memory impairment, axonal atrophy, and synaptic loss are ameliorated by M1, a metabolite of protopanaxadiol-type saponins
-
Tohda C, Matsumoto N, Zou K, Meselhy MR, Komatsu K. Ab(25-35)- induced memory impairment, axonal atrophy, and synaptic loss are ameliorated by M1, a metabolite of protopanaxadiol-type saponins. Neuropsychopharmacology 2004;29:860-8.
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 860-868
-
-
Tohda, C.1
Matsumoto, N.2
Zou, K.3
Meselhy, M.R.4
Komatsu, K.5
-
15
-
-
0025518656
-
Preliminary study on antiamnesic mechanism of Rg1 and Rb1
-
Zhang JT, Qu ZW, Liu Y, Deng HL. Preliminary study on antiamnesic mechanism of Rg1 and Rb1. Chin Med J 1990;103:932-8.
-
(1990)
Chin Med J
, vol.103
, pp. 932-938
-
-
Zhang, J.T.1
Qu, Z.W.2
Liu, Y.3
Deng, H.L.4
-
16
-
-
0036180097
-
Neuroprotective effects of ginseng total saponin and ginsenosides Rb1 and Rg1 on spinal cord neurons in vitro
-
Liao B, Newmark H, Zhou R. Neuroprotective effects of ginseng total saponin and ginsenosides Rb1 and Rg1 on spinal cord neurons in vitro. Experiment Neurol 2002;173:224-34.
-
(2002)
Experiment Neurol
, vol.173
, pp. 224-234
-
-
Liao, B.1
Newmark, H.2
Zhou, R.3
-
17
-
-
0028183354
-
Malonyl-ginsenoside Rb1 potentiates nerve growth factor (NGF)-induced neurite outgrowth of cultured chick embryonic dorsal root ganglia
-
Nishiyama N, Cho SI, Kitagawa I, Saito H. Malonyl-ginsenoside Rb1 potentiates nerve growth factor (NGF)-induced neurite outgrowth of cultured chick embryonic dorsal root ganglia. Biol Pharmacol Bull 1994;17:509-13.
-
(1994)
Biol Pharmacol Bull
, vol.17
, pp. 509-513
-
-
Nishiyama, N.1
Cho, S.I.2
Kitagawa, I.3
Saito, H.4
-
18
-
-
23344454232
-
Memory enhancing and neuroprotective effects of selected ginsenosides
-
Bao HY, Zhang J, Yeo SJ, Myung CS, Kim HM, Kim JM, Park JH, Cho JS, Kang JS. Memory enhancing and neuroprotective effects of selected ginsenosides. Arch Pharm Res 2005;28:335-42.
-
(2005)
Arch Pharm Res
, vol.28
, pp. 335-342
-
-
Bao, H.Y.1
Zhang, J.2
Yeo, S.J.3
Myung, C.S.4
Kim, H.M.5
Kim, J.M.6
Park, J.H.7
Cho, J.S.8
Kang, J.S.9
-
19
-
-
83455245428
-
Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model
-
Fang F, Chen X, Huang T, Lue LF, Luddy JS, Yan SS. Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model. Biochim Biophys Acta 2012;1822:286-92.
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 286-292
-
-
Fang, F.1
Chen, X.2
Huang, T.3
Lue, L.F.4
Luddy, J.S.5
Yan, S.S.6
-
20
-
-
70349958198
-
Ginsenoside Rh2 ameliorates scopolamine-induced learning deficit in mice
-
Yang JH, Han SJ, Ryu JH, Kang IS, Kim DH. Ginsenoside Rh2 ameliorates scopolamine-induced learning deficit in mice. Biol Pharm Bull 2009;32: 1710-5.
-
(2009)
Biol Pharm Bull
, vol.32
, pp. 1710-1715
-
-
Yang, J.H.1
Han, S.J.2
Ryu, J.H.3
Kang, I.S.4
Kim, D.H.5
-
21
-
-
77954086949
-
The validity of scopolamine as a pharmacological model for cognitive impairment: A review of animal behavioral studies
-
Klinkenberg I, Blokland A. The validity of scopolamine as a pharmacological model for cognitive impairment: a review of animal behavioral studies. Neurosci Biobehav Rev 2010;34:1307-50.
-
(2010)
Neurosci Biobehav Rev
, vol.34
, pp. 1307-1350
-
-
Klinkenberg, I.1
Blokland, A.2
-
22
-
-
16544366501
-
Ginsenosides inhibit NMDA receptor-mediated epileptic discharges in cultured hippocampal neurons
-
Kim S, Rhim H. Ginsenosides inhibit NMDA receptor-mediated epileptic discharges in cultured hippocampal neurons. Arch Pharm Res 2004;27:524-30.
-
(2004)
Arch Pharm Res
, vol.27
, pp. 524-530
-
-
Kim, S.1
Rhim, H.2
-
23
-
-
20144389219
-
Protective effects of ginseng saponins on 3-nitropropionic acid-induced striatal degeneration in rats
-
Kim JH, Kim S, Yoon IS, Lee JH, Jang BJ, Jeong SM, Lee JH, Lee BH, Han JS, Oh S, et al. Protective effects of ginseng saponins on 3-nitropropionic acid-induced striatal degeneration in rats. Neuropharmacology 2005;48:743-56.
-
(2005)
Neuropharmacology
, vol.48
, pp. 743-756
-
-
Kim, J.H.1
Kim, S.2
Yoon, I.S.3
Lee, J.H.4
Jang, B.J.5
Jeong, S.M.6
Lee, J.H.7
Lee, B.H.8
Han, J.S.9
Oh, S.10
-
24
-
-
79951804440
-
Neuroprotective effects of ginsenoside Rg3 against 24-OH-cholesterol-induced cytotoxicity in cortical neurons
-
Roh YS, Kim HB, Kang CW, Kim BS, Nah SY, Kim JH. Neuroprotective effects of ginsenoside Rg3 against 24-OH-cholesterol-induced cytotoxicity in cortical neurons. J Ginseng Res 2010;34:246-53.
-
(2010)
J Ginseng Res
, vol.34
, pp. 246-253
-
-
Roh, Y.S.1
Kim, H.B.2
Kang, C.W.3
Kim, B.S.4
Nah, S.Y.5
Kim, J.H.6
-
25
-
-
11844298464
-
Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats
-
Tian J, Fu F, Geng M, Jiang Y, Yang J, Jiang W, Wang C, Liu K. Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats. Neurosci Lett 2005;374:92-7.
-
(2005)
Neurosci Lett
, vol.374
, pp. 92-97
-
-
Tian, J.1
Fu, F.2
Geng, M.3
Jiang, Y.4
Yang, J.5
Jiang, W.6
Wang, C.7
Liu, K.8
-
26
-
-
0036386954
-
Inhibitory effect of ginsenosides on NMDA receptor-mediated signals in rat hippocampal neurons
-
Kim S, Ahn K, Oh TH, Nah SY, Rhim H. Inhibitory effect of ginsenosides on NMDA receptor-mediated signals in rat hippocampal neurons. Biochem Biophys Res Commun 2002;296:247-54.
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 247-254
-
-
Kim, S.1
Ahn, K.2
Oh, T.H.3
Nah, S.Y.4
Rhim, H.5
-
27
-
-
33845672995
-
Reductions in levels of the Alzheimer's amyloid b peptide after oral administration of ginsenosides
-
Chen F, Eckman E, Eckman C. Reductions in levels of the Alzheimer's amyloid b peptide after oral administration of ginsenosides. FASEB J 2006;20:1269-71.
-
(2006)
FASEB J
, vol.20
, pp. 1269-1271
-
-
Chen, F.1
Eckman, E.2
Eckman, C.3
-
28
-
-
79951792885
-
Increase of functional saponin by acidic treatment and temperature of red ginseng extract
-
In JG, Lee BS, Kim EJ, Park MH, Yang DC. Increase of functional saponin by acidic treatment and temperature of red ginseng extract. Korea J Plant Res 2006;19:139-43.
-
(2006)
Korea J Plant Res
, vol.19
, pp. 139-143
-
-
In, J.G.1
Lee, B.S.2
Kim, E.J.3
Park, M.H.4
Yang, D.C.5
-
29
-
-
33947727024
-
The ameliorating effect of oroxylin A on scopolamine-induced memory impairment in mice
-
Kim DH, Jeon SJ, Son KH, Jung JW, Lee SJ, Yoon BH, Lee JJ, Cho YW, Cheong JH, Ko KH, et al. The ameliorating effect of oroxylin A on scopolamine-induced memory impairment in mice. Neurobiol Learn Mem 2007;87:536-46.
-
(2007)
Neurobiol Learn Mem
, vol.87
, pp. 536-546
-
-
Kim, D.H.1
Jeon, S.J.2
Son, K.H.3
Jung, J.W.4
Lee, S.J.5
Yoon, B.H.6
Lee, J.J.7
Cho, Y.W.8
Cheong, J.H.9
Ko, K.H.10
-
30
-
-
84862662586
-
A comparison between extract products of Magnolia officinalis on memory impairment and amyloidogenesis in a transgenic mouse model of Alzheimer's disease
-
Lee YJ, Choi DY, Han SB, Kim YH, Kim KH, Seong YH, Oh KW, Hong TJ. A comparison between extract products of Magnolia officinalis on memory impairment and amyloidogenesis in a transgenic mouse model of Alzheimer's disease. Biomol Ther 2012;20:332-9.
-
(2012)
Biomol Ther
, vol.20
, pp. 332-339
-
-
Lee, Y.J.1
Choi, D.Y.2
Han, S.B.3
Kim, Y.H.4
Kim, K.H.5
Seong, Y.H.6
Oh, K.W.7
Hong, T.J.8
-
31
-
-
0037897480
-
Anti-amnesic activity of E-p-methoxycinnamic acid from Scrophularia buergeriana
-
Kim SR, Kang SY, Lee KY, Kim SH, Markeloni GJ, Oh TH, Kim CK. Anti-amnesic activity of E-p-methoxycinnamic acid from Scrophularia buergeriana. Brain Res Cog Brain Res 2003;17:454-61.
-
(2003)
Brain Res Cog Brain Res
, vol.17
, pp. 454-461
-
-
Kim, S.R.1
Kang, S.Y.2
Lee, K.Y.3
Kim, S.H.4
Markeloni, G.J.5
Oh, T.H.6
Kim, C.K.7
-
33
-
-
84866005647
-
The memory ameliorating effects of INM-176, an ethanolic extract of Angelica gigas, against scopolamine- or Ab1-42-induced cognitive dysfunction in mice
-
Park SJ, Jung JM, Lee HE, Lee YW, Kim DH, Kim JM, Hong JG, Lee CH, Jung IH, Cho YB, et al. The memory ameliorating effects of INM-176, an ethanolic extract of Angelica gigas, against scopolamine- or Ab1-42-induced cognitive dysfunction in mice. J Ethnopharmacology 2012;143:611-20.
-
(2012)
J Ethnopharmacology
, vol.143
, pp. 611-620
-
-
Park, S.J.1
Jung, J.M.2
Lee, H.E.3
Lee, Y.W.4
Kim, D.H.5
Kim, J.M.6
Hong, J.G.7
Lee, C.H.8
Jung, I.H.9
Cho, Y.B.10
-
34
-
-
0018627150
-
Spatial memory and hippocampal function
-
Olton DS, Papas BC. Spatial memory and hippocampal function. Neuropsychologia 1979;17:669-82.
-
(1979)
Neuropsychologia
, vol.17
, pp. 669-682
-
-
Olton, D.S.1
Papas, B.C.2
-
35
-
-
0030593636
-
Role of dorsal hippocampus in acquisition, consolidation and retrieval of rat's passive avoidance response: A tetrodotoxin functional inactivation study
-
Lorenzini CA, Baldi E, Bucherelli C, Sacchetti B, Tassoni G. Role of dorsal hippocampus in acquisition, consolidation and retrieval of rat's passive avoidance response: a tetrodotoxin functional inactivation study. Brain Res 1996;730: 32-9.
-
(1996)
Brain Res
, vol.730
, pp. 32-39
-
-
Lorenzini, C.A.1
Baldi, E.2
Bucherelli, C.3
Sacchetti, B.4
Tassoni, G.5
-
36
-
-
0029924670
-
Effects of the uncompetitive NMDA receptor antagonist memantine on hippocampal long-term potentiation, shortterm exploratory modulation and spatial memory in awake, freely moving rats
-
Barnes CA, Danysz W, Parsons CG. Effects of the uncompetitive NMDA receptor antagonist memantine on hippocampal long-term potentiation, shortterm exploratory modulation and spatial memory in awake, freely moving rats. Eur J Neurosci 1996;8:565-71.
-
(1996)
Eur J Neurosci
, vol.8
, pp. 565-571
-
-
Barnes, C.A.1
Danysz, W.2
Parsons, C.G.3
-
37
-
-
0021173996
-
Development of a water maze procedure for studying spatial learning in the rat
-
Morris RG. Development of a water maze procedure for studying spatial learning in the rat. J Neurosci Methods 1984;11:47-60.
-
(1984)
J Neurosci Methods
, vol.11
, pp. 47-60
-
-
Morris, R.G.1
-
38
-
-
84872358224
-
The revival of scopolamine reversal for the assessment of cognition-enhancing drugs
-
Buccafusco JJ, editor, 2nd ed. Florida: CRC Press
-
Buccafusco JJ. The revival of scopolamine reversal for the assessment of cognition-enhancing drugs. In: Buccafusco JJ, editor. Methods of behavior analysis in neuroscience. 2nd ed. Florida: CRC Press; 2009. Ch. 17:329-43.
-
(2009)
Methods of Behavior Analysis In Neuroscience
, vol.17
, pp. 329-343
-
-
Buccafusco, J.J.1
-
39
-
-
0022643823
-
Non-cholinergic neurotransmitter abnormalities in Alzheimer's disease
-
Rossor M, Iversen LL. Non-cholinergic neurotransmitter abnormalities in Alzheimer's disease. Brit Med Bull 1986;42:70-4.
-
(1986)
Brit Med Bull
, vol.42
, pp. 70-74
-
-
Rossor, M.1
Iversen, L.L.2
-
40
-
-
0037622682
-
Nicotinic acetylcholine receptor-mediated neuroprotection by donezepil against glutamate neurotoxicity in rat cortical neurons
-
Takada Y, Yonezawa A, Kume T, Katsuki H, Kaneko S, Sugimoto H, et al. Nicotinic acetylcholine receptor-mediated neuroprotection by donezepil against glutamate neurotoxicity in rat cortical neurons. J Pharmacol Exp Ther 2003;306:772-7.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 772-777
-
-
Takada, Y.1
Yonezawa, A.2
Kume, T.3
Katsuki, H.4
Kaneko, S.5
Sugimoto, H.6
-
41
-
-
12344319426
-
Effect of acidic oligosaccharide sugar chain on scopolamine-induced memory impairment in rats and its related mechanisms
-
Fan Y, Hu J, Li J, Yang Z, Xin X, Wang J, Ding J, Geng M. Effect of acidic oligosaccharide sugar chain on scopolamine-induced memory impairment in rats and its related mechanisms. Neurosci Lett 2005;374:222-6.
-
(2005)
Neurosci Lett
, vol.374
, pp. 222-226
-
-
Fan, Y.1
Hu, J.2
Li, J.3
Yang, Z.4
Xin, X.5
Wang, J.6
Ding, J.7
Geng, M.8
-
42
-
-
84874114021
-
Ginsenoside Rg5 and Rh3 protect scopolamine-induced memory deficits in mice
-
Kim EJ, Jung IH, Van Le TK, Jeong JJ, Kim NJ, Kim DH. Ginsenoside Rg5 and Rh3 protect scopolamine-induced memory deficits in mice. J Ethnopharmacol 2013;146:294-9.
-
(2013)
J Ethnopharmacol
, vol.146
, pp. 294-299
-
-
Kim, E.J.1
Jung, I.H.2
van Le, T.K.3
Jeong, J.J.4
Kim, N.J.5
Kim, D.H.6
|