Hypusine modification of the ribosome-binding protein eIF5A, a target for new anti-inflammatory drugs: Understanding the action of the inhibitor GC7 on a murine macrophage cell line

Current Pharmaceutical Design

Volumn 20, Issue 2, 2014, Pages 284-292

  de Almeida Jr , Oedem Paulo ^a   Toledo, Thais Regina ^a   Rossi, Danuza ^a   Rossetto, Daniella de Barros ^a   Watanabe, Tatiana Faria ^a   Galvão, Fábio Carrilho ^a   Medeiros, Alexandra Ivo ^a   Zanelli, Cleslei Fernando ^a   Valentini, Sandro Roberto ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Anti inflammatory drugs; CG7; EIF5A; Hypusine modification inhibitor; TNF

Indexed keywords

ANTIINFLAMMATORY AGENT; HYPUSINE; INITIATION FACTOR 5A; MESSENGER RNA; POLYAMINE; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; CELL CULTURE; CYTOTOXICITY; HUMAN; INFLAMMATION; MACROPHAGE; NONHUMAN; POLYSOME; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; REVIEW; RNA ISOLATION; RNA TRANSLATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CYTOKINES; GUANINE; HUMANS; INFLAMMATION; LYSINE; MACROPHAGES; MICE; MOLECULAR TARGETED THERAPY; NITRIC OXIDE; PEPTIDE INITIATION FACTORS; RNA-BINDING PROTEINS;

EID: 84892960491     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/13816128113199990036     Document Type: Review

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