Screening assay for the identification of deoxyhypusine synthase inhibitors

Journal of Biomolecular Screening

Volumn 9, Issue 5, 2004, Pages 434-438

  Sommer, Marc Nicola ^a   Bevec, Dorian ^a   Klebl, Bert ^a   Flicke, Birgit ^a   Hölscher, Kerstin ^a   Freudenreich, Tatjana ^a   Hauber, Ilona ^b   Hauber, Joachim ^b   Mett, Helmut ^a  

^a Axxima Pharmaceuticals AG   (Germany)

^b LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

Author keywords

96 well; DHS; eIF5A; HIV; Spermidine

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTINEOPLASTIC AGENT; AXD 455; DEOXYHYPUSINE SYNTHASE; DEOXYHYPUSINE SYNTHASE INHIBITOR; HYPUSINE; INITIATION FACTOR 5A; REV PROTEIN; SEMAPIMOD; SPERMIDINE; UNCLASSIFIED DRUG; EIF-5A; ENZYME INHIBITOR; HYDRAZONE DERIVATIVE; INITIATION FACTOR; OXIDOREDUCTASE; RECOMBINANT PROTEIN; RNA BINDING PROTEIN;

ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CATALYSIS; CELL GROWTH; DRUG IDENTIFICATION; DRUG POTENCY; ENZYME INHIBITION; EUKARYOTIC CELL; HIGH THROUGHPUT SCREENING; HUMAN IMMUNODEFICIENCY VIRUS; HYDROXYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; VIRUS REPLICATION; CHEMISTRY; DRUG ANTAGONISM; ISOLATION AND PURIFICATION; POLYACRYLAMIDE GEL ELECTROPHORESIS;

EUKARYOTA;

ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; HYDRAZONES; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PEPTIDE INITIATION FACTORS; RECOMBINANT PROTEINS; RNA-BINDING PROTEINS;

EID: 15244361021     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057104264031     Document Type: Article

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