Hepatoprotective effect of cryptotanshinone from Salvia miltiorrhiza in d-galactosamine/lipopolysaccharide-induced fulminant hepatic failure

Phytomedicine

Volumn 21, Issue 2, 2014, Pages 141-147

  Jin, Quan ^a   Jiang, Shuang ^a   Wu, Yan Ling ^a   Bai, Ting ^a   Yang, Yong ^a   Jin, Xuejun ^a   Lian, Li Hua ^a   Nan, Ji Xing ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

Apoptosis; Cryptotanshinone; Fulminant hepatic failure; NF B; Salvia miltiorrhiza

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 8; CASPASE 9; CRYPTOTANSHINONE; CYTOCHROME C; DEOXYADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; GALACTOSAMINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SILYMARIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CYTOKINE PRODUCTION; DNA FRAGMENTATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FULMINANT HEPATIC FAILURE; IMMUNOBLOTTING; LIVER CELL; LIVER HISTOLOGY; LIVER PROTECTION; MALE; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALVIA MILTIORRHIZA;

SALVIA MILTIORRHIZA;

ALANINE AMINOTRANSFERASE; ALT; APOPTOSIS; ASPARTATE AMINOTRANSFERASE; AST; C-JUN N-TERMINAL KINASE; CRYPTOTANSHINONE; D-GALACTOSAMINE; ERK; EXTRACELLULAR SIGNAL REGULATED KINASE; FHF; FULMINANT HEPATIC FAILURE; GALN; GAPDH; GLYCERALDEHYDES-3-PHOSPHATE DEHYDROGENASE; IL-1; INTERLEUKIN-1; JNK; LIPOPOLYSACCHARIDE; LPS; MAPK; MITOGEN-ACTIVATED PROTEIN KINASES; NF-ΚB; NUCLEAR FACTOR-ΚB; SALVIA MILTIORRHIZA; TAK1; TGF-Β-ACTIVATED KINASE 1; TNF-Α; TUMOR NECROSIS FACTOR-Α;

ANIMALS; ANTI-INFLAMMATORY AGENTS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; CASPASES; CYTOCHROMES C; DRUG-INDUCED LIVER INJURY; GALACTOSAMINE; LIPOPOLYSACCHARIDES; LIVER; LIVER FAILURE, ACUTE; MALE; MAP KINASE KINASE KINASES; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHENANTHRENES; PHYTOTHERAPY; PLANT EXTRACTS; SALVIA MILTIORRHIZA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84892936795     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.07.016     Document Type: Article

References (28)

1. E. Abraham Nuclear factor-kappaB and its role in sepsis-associated organ failure Journal of Infectious Diseases 187 Suppl. 2 2003 S364 S369
2. B.B. Aggarwal Nuclear factor-kappaB: the enemy within Cancer Cell 6 2004 203 208
3. G. Bonizzi, and M. Karin The two NF-kappaB activation pathways and their role in innate and adaptive immunity Trends in Immunology 25 2004 280 288
4. J.G. Chosay, N.A. Essani, C.J. Dunn, and H. Jaeschke Neutrophil margination and extravasation in sinusoids and venules of liver during endotoxin-induced injury American Journal of Physiology 272 1997 G1195 G1200
5. M.W. Covert, T.H. Leung, J.E. Gaston, and D. Baltimore Achieving stability of lipopolysaccharide-induced NF-kappaB activation Science 309 2005 1854 1857
6. H. Frobose, S.G. Ronn, P.E. Heding, H. Mendoza, P. Cohen, T. Mandrup-Poulsen, and N. Billestrup Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex Molecular Endocrinology 20 2006 1587 1596
7. I. Hishinuma, J. Nagakawa, K. Hirota, K. Miyamoto, K. Tsukidate, T. Yamanaka, K. Katayama, and I. Yamatsu Involvement of tumor necrosis factor-alpha in development of hepatic injury in galactosamine-sensitized mice Hepatology 12 1990 1187 1191
8. H. Holtmann, J. Enninga, S. Kalble, A. Thiefes, A. Dorrie, M. Broemer, R. Winzen, A. Wilhelm, J. Ninomiya-Tsuji, K. Matsumoto, K. Resch, and M. Kracht The MAPK kinase kinase TAK1 plays a central role in coupling the interleukin-1 receptor to both transcriptional and RNA-targeted mechanisms of gene regulation Journal of Biological Chemistry 276 2001 3508 3516
9. T. Huxford, and G. Ghosh A structural guide to proteins of the NF-kappaB signaling module Cold Spring Harbor Perspectives in Biology 1 2009 a000075
10. H. Jaeschke, M.A. Fisher, J.A. Lawson, C.A. Simmons, A. Farhood, and D.A. Jones Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model Journal of Immunology 160 1998 3480 3486
11. M. Karin, and Y. Ben-Neriah Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity Annual Review of Immunology 18 2000 621 663
12. E.K. Kim, and E.J. Choi Pathological roles of MAPK signaling pathways in human diseases Biochimica et Biophysica Acta 1802 2010 396 405
13. W.Y. Lee, K.W. Liu, and J.H. Yeung Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells Cancer Letters 285 2009 46 57
14. X. Li, L.H. Lian, T. Bai, Y.L. Wu, Y. Wan, W.X. Xie, X. Jin, and J.X. Nan Cryptotanshinone inhibits LPS-induced proinflammatory mediators via TLR4 and TAK1 signaling pathway International Immunopharmacology 11 2011 1871 1876
15. L.H. Lian, X. Jin, Y.L. Wu, X.F. Cai, J.J. Lee, and J.X. Nan Hepatoprotective effects of Sedum sarmentosum on d-galactosamine/ lipopolysaccharide-induced murine fulminant hepatic failure Journal of Pharmacological Sciences 114 2010 147 157
16. L.H. Lian, Y.L. Wu, Y. Wan, X. Li, W.X. Xie, and J.X. Nan Anti-apoptotic activity of gentiopicroside in d-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure Chemico-Biological Interactions 188 2010 127 133
17. E. Liaskou, D.V. Wilson, and Y.H. Oo Innate immune cells in liver inflammation Mediators of Inflammation 2012 2012 949157
18. A. Mignon, N. Rouquet, M. Fabre, S. Martin, J.C. Pages, J.F. Dhainaut, A. Kahn, P. Briand, and V. Joulin LPS challenge in d-galactosamine-sensitized mice accounts for caspase-dependent fulminant hepatitis, not for septic shock American Journal of Respiratory and Critical Care Medicine 159 1999 1308 1315
19. H. Nakagawa, and S. Maeda Molecular mechanisms of liver injury and hepatocarcinogenesis: focusing on the role of stress-activated MAPK Pathology Research International 2012 2012 172894
20. J.X. Nan, E.J. Park, J.B. Nam, Y.Z. Zhao, X.F. Cai, Y.H. Kim, D.H. Sohn, and J.J. Lee Effect of Acanthopanax koreanum Nakai (Araliaceae) on d-galactosamine and lipopolysaccharide-induced fulminant hepatitis Journal of Ethnopharmacology 92 2004 71 77
21. E.J. Park, Y.Z. Zhao, Y.C. Kim, and D.H. Sohn Preventive effects of a purified extract isolated from Salvia miltiorrhiza enriched with tanshinone I, tanshinone IIA and cryptotanshinone on hepatocyte injury in vitro and in vivo Food and Chemical Toxicology 47 2009 2742 2748
22. S.K. Ramaiah, and H. Jaeschke Role of neutrophils in the pathogenesis of acute inflammatory liver injury Toxicologic Pathology 35 2007 757 766
23. S. Tang, X.Y. Shen, H.Q. Huang, S.W. Xu, Y. Yu, C.H. Zhou, S.R. Chen, K. Le, Y.H. Wang, and P.Q. Liu Cryptotanshinone suppressed inflammatory cytokines secretion in RAW264.7 macrophages through inhibition of the NF-kappaB and MAPK signaling pathways Inflammation 34 2011 111 118
24. A. Thiefes, S. Wolter, J.F. Mushinski, E. Hoffmann, O. Dittrich-Breiholz, N. Graue, A. Dorrie, H. Schneider, D. Wirth, B. Luckow, K. Resch, and M. Kracht Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes Journal of Biological Chemistry 280 2005 27728 27741
25. D.H. Van Thiel, J. Brems, A. Nadir, R. Idilman, A. Colantoni, D. Holt, and S. Edelstein Liver transplantation for fulminant hepatic failure Journal of Gastroenterology 37 Suppl. 13 2002 78 81
26. Y. Wan, Y.L. Wu, X.C. Feng, L.H. Lian, Y.Z. Jiang, and J.X. Nan The protective effects of total saponins from Ornithogalum saundersiae (Liliaceae) on acute hepatic failure induced by lipopolysaccharide and d-galactosamine in mice Journal of Ethnopharmacology 132 2010 450 455
27. H. Wagner, and G. Ulrich-Merzenich Evidence and Rational Based Research on Chinese Drugs 2013 Springer Wien-New York 237 282 (Chapter 6)
28. G.X. Zhong, P. Li, L.J. Zeng, J. Guan, D.Q. Li, and S.P. Li Chemical characteristics of Salvia miltiorrhiza (Danshen) collected from different locations in China Journal of Agricultural and Food Chemistry 57 2009 6879 6887