Deciphering the neuroprotective mechanisms of Bu-yang Huan-wu decoction by an integrative neurofunctional and genomic approach in ischemic stroke mice

Journal of Ethnopharmacology

Volumn 138, Issue 1, 2011, Pages 22-33

  Wang, Hsei Wei ^b   Liou, Kuo Tong ^c   Wang, Yea Hwey ^e   Lu, Chung Kuang ^a   Lin, Yun Lian ^a   Lee, I Jung ^a   Huang, Sheng Teng ^f   Tsai, Yuan Hau ^b   Cheng, Yi Chieh ^b   Lin, Hung Jui ^b   Shen, Yuh Chiang ^a,d  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c CHINESE CULTURE UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^e HUNGKUANG UNIVERSITY   (Taiwan)

^f CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Apoptosis; Bu yang Huan wu decoction; Cerebral ischemia reperfusion (CI R); Functional modules and genetic networks; Genome wide transcriptome analysis; Infarction; Inflammation; Mice; Microarray; Neurogenesis; Neurological deficits; Oxidative stress; Positron emission tomography (PET)

Indexed keywords

ALTEPLASE; BU YANG HUAN WU DECOCTION; CHINESE DRUG; DIZOCILPINE; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD CLOTTING; BRAIN FUNCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; DEATH; DRUG EFFECT; DRUG MECHANISM; GENETIC ANALYSIS; GENOMICS; INFLAMMATION; LIFESPAN; MALE; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SURVIVAL RATE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; APOPTOSIS; ASTRAGALUS PLANT; BLOOD COAGULATION; BRAIN; BRAIN ISCHEMIA; CEREBRAL INFARCTION; DRUGS, CHINESE HERBAL; GENE EXPRESSION; INFLAMMATION; MALE; MICE; MICE, INBRED ICR; NEOVASCULARIZATION, PHYSIOLOGIC; NEUROGENESIS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PHYTOTHERAPY; STROKE; TISSUE PLASMINOGEN ACTIVATOR;

MUS;

EID: 80255137424     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.06.033     Document Type: Article

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