Dendropanoxide induces autophagy through ERK1/2 activation in MG-63 human osteosarcoma cells and autophagy inhibition enhances dendropanoxide-induced apoptosis

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Lee, Ji Won ^a   Kim, Kyoung Sook ^a   An, Hyun Kyu ^a   Kim, Cheorl Ho ^b   Moon, Hyung In ^a   Lee, Young Choon ^a  

^a Dong A University   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; ANTINEOPLASTIC AGENT; ATG7 PROTEIN; BECLIN 1; BIOLOGICAL MARKER; CASPASE; CYTOCHROME C; DENDROPANOXIDE; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG; WORTMANNIN;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARALIACEAE; ARTICLE; AUTOPHAGY; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; DENDROPANAX MORBIFERA; DOSE TIME EFFECT RELATION; DRUG POTENTIATION; HUMAN; HUMAN CELL; OSTEOSARCOMA CELL; PLANT LEAF; PLANT STEM; PROTEIN PHOSPHORYLATION;

ADENINE; APOPTOSIS; AUTOPHAGY; BONE NEOPLASMS; CELL SURVIVAL; ENZYME ACTIVATION; HUMANS; MAP KINASE SIGNALING SYSTEM; NEOPLASMS; OSTEOSARCOMA; TRITERPENES; TUMOR CELLS, CULTURED;

EID: 84892906847     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083611     Document Type: Article

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