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Volumn 8, Issue 12, 2013, Pages

Valproic acid causes proteasomal degradation of DICER and influences miRNA expression

Author keywords

[No Author keywords available]

Indexed keywords

DICER; MICRORNA; VALPROIC ACID;

EID: 84892906480     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082895     Document Type: Article
Times cited : (31)

References (48)
  • 1
    • 0037282719 scopus 로고    scopus 로고
    • Drug treatment of epilepsy in elderly people: Focus on valproic Acid
    • PubMed: 12534314
    • Stephen LJ (2003) Drug treatment of epilepsy in elderly people: focus on valproic Acid. Drugs Aging 20: 141-152. PubMed: 12534314.
    • (2003) Drugs Aging , vol.20 , pp. 141-152
    • Stephen, L.J.1
  • 2
    • 41149109098 scopus 로고    scopus 로고
    • Use of intravenous valproic acid for acute migraine
    • doi:10.1345/aph.1K531. PubMed: 18303140
    • Frazee LA, Foraker KC (2008) Use of intravenous valproic acid for acute migraine. Ann Pharmacother 42: 403-407. doi:10.1345/aph.1K531. PubMed: 18303140.
    • (2008) Ann Pharmacother , vol.42 , pp. 403-407
    • Frazee, L.A.1    Foraker, K.C.2
  • 3
    • 35248894933 scopus 로고    scopus 로고
    • The mechanisms of action of valproate in neuropsychiatric disorders: Can we see the forest for the trees?
    • doi:10.1007/s00018-007-7079-x. PubMed: 17514356
    • Rosenberg G (2007) The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees? Cell Mol Life Sci 64: 2090-2103. doi:10.1007/s00018-007-7079-x. PubMed: 17514356.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 2090-2103
    • Rosenberg, G.1
  • 4
    • 79959988589 scopus 로고    scopus 로고
    • SMA CARNIVAL TRIAL PART II: A prospective, single-armed trial of L-carnitine and valproic acid in ambulatory children with spinal muscular atrophy
    • doi:10.1371/journal.pone.0021296. PubMed: 21754985
    • Kissel JT, Scott CB, Reyna SP, Crawford TO, Simard LR et al. (2011) SMA CARNIVAL TRIAL PART II: a prospective, single-armed trial of L-carnitine and valproic acid in ambulatory children with spinal muscular atrophy. PLOS ONE 6: e21296. doi:10.1371/journal.pone.0021296. PubMed: 21754985.
    • (2011) PLOS ONE , vol.6
    • Kissel, J.T.1    Scott, C.B.2    Reyna, S.P.3    Crawford, T.O.4    Simard, L.R.5
  • 5
    • 77649171884 scopus 로고    scopus 로고
    • Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
    • PubMed: 20132536
    • Tan J, Cang S, Ma Y, Petrillo RL, Liu D (2010) Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents. J Hematol Oncol 3: 5. PubMed: 20132536.
    • (2010) J Hematol Oncol , vol.3 , pp. 5
    • Tan, J.1    Cang, S.2    Ma, Y.3    Petrillo, R.L.4    Liu, D.5
  • 6
    • 42649109021 scopus 로고    scopus 로고
    • Valproic acid as epigenetic cancer drug: Preclinical, clinical and transcriptional effects on solid tumors
    • doi:10.1016/j.ctrv.2007.11.003. PubMed: 18226465
    • Duenas-Gonzalez A, Candelaria M, Perez-Plascencia C, Perez-Cardenas E, de la Cruz-Hernandez E et al. (2008) Valproic acid as epigenetic cancer drug: preclinical, clinical and transcriptional effects on solid tumors. Cancer Treat Rev 34: 206-222. doi:10.1016/j.ctrv.2007.11.003. PubMed: 18226465.
    • (2008) Cancer Treat Rev , vol.34 , pp. 206-222
    • Duenas-Gonzalez, A.1    Candelaria, M.2    Perez-Plascencia, C.3    Perez-Cardenas, E.4    De La Cruz-Hernandez, E.5
  • 7
    • 36749072618 scopus 로고    scopus 로고
    • Valproic acid as anti-cancer drug
    • doi:10.2174/138161207782360528. PubMed: 18045192
    • Michaelis M, Doerr HW, Cinatl J Jr. (2007) Valproic acid as anti-cancer drug. Curr Pharm Des 13: 3378-3393. doi:10.2174/138161207782360528. PubMed: 18045192.
    • (2007) Curr Pharm des , vol.13 , pp. 3378-3393
    • Michaelis, M.1    Doerr, H.W.2    Cinatl Jr., J.3
  • 8
    • 0035965343 scopus 로고    scopus 로고
    • Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
    • doi:10.1074/jbc.M101287200. PubMed: 11473107
    • Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA et al. (2001) Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 276: 36734-36741. doi:10.1074/jbc. M101287200. PubMed: 11473107.
    • (2001) J Biol Chem , vol.276 , pp. 36734-36741
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Guenther, M.G.4    Lazar, M.A.5
  • 9
    • 0035943699 scopus 로고    scopus 로고
    • The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth
    • doi:10.1074/jbc.M104309200. PubMed: 11418608
    • Yuan PX, Huang LD, Jiang YM, Gutkind JS, Manji HK et al. (2001) The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. J Biol Chem 276: 31674-31683. doi:10.1074/jbc. M104309200. PubMed: 11418608.
    • (2001) J Biol Chem , vol.276 , pp. 31674-31683
    • Yuan, P.X.1    Huang, L.D.2    Jiang, Y.M.3    Gutkind, J.S.4    Manji, H.K.5
  • 10
    • 0037925520 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2
    • doi:10.1093/emboj/cdg315. PubMed: 12840003
    • Krämer OH, Zhu P, Ostendorff HP, Golebiewski M, Tiefenbach J et al. (2003) The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2. EMBO J 22: 3411-3420. doi:10.1093/emboj/ cdg315. PubMed: 12840003.
    • (2003) EMBO J , vol.22 , pp. 3411-3420
    • Krämer, O.H.1    Zhu, P.2    Ostendorff, H.P.3    Golebiewski, M.4    Tiefenbach, J.5
  • 11
    • 63849224411 scopus 로고    scopus 로고
    • Involvement of PML nuclear bodies in CBP degradation through the ubiquitin-proteasome pathway
    • doi:10.4161/epi.3.6.7203. PubMed: 19011377
    • St-Germain JR, Chen J, Li Q (2008) Involvement of PML nuclear bodies in CBP degradation through the ubiquitin-proteasome pathway. Epigenetics : Official Journal of the DNA Methylation Society 3: 342-349. doi:10.4161/epi.3.6.7203. PubMed: 19011377.
    • (2008) Epigenetics: Official Journal of the DNA Methylation Society , vol.3 , pp. 342-349
    • St-Germain, J.R.1    Chen, J.2    Li, Q.3
  • 12
    • 67650360880 scopus 로고    scopus 로고
    • Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons through its epigenetic actions
    • doi:10.1016/j.neures.2009.09.1698. PubMed: 19463867
    • Fukuchi M, Nii T, Ishimaru N, Minamino A, Hara D et al. (2009) Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons through its epigenetic actions. Neurosci Res 65: 35-43. doi:10.1016/j.neures.2009.09.1698. PubMed: 19463867.
    • (2009) Neurosci Res , vol.65 , pp. 35-43
    • Fukuchi, M.1    Nii, T.2    Ishimaru, N.3    Minamino, A.4    Hara, D.5
  • 13
    • 20344395892 scopus 로고    scopus 로고
    • Microarray analysis of rat brain gene expression after chronic administration of sodium valproate
    • Bosetti F, Bell JM, Manickam P (2005) Microarray analysis of rat brain gene expression after chronic administration of sodium valproate. Brain research bulletin 65: 331-338.
    • (2005) Brain Research Bulletin , vol.65 , pp. 331-338
    • Bosetti, F.1    Bell, J.M.2    Manickam, P.3
  • 15
    • 58849112575 scopus 로고    scopus 로고
    • Biogenesis of small RNAs in animals
    • doi:10.1038/nrm2632. PubMed: 19165215
    • Kim VN, Han J, Siomi MC (2009) Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol 10: 126-139. doi:10.1038/nrm2632. PubMed: 19165215.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 126-139
    • Kim, V.N.1    Han, J.2    Siomi, M.C.3
  • 16
    • 77952479722 scopus 로고    scopus 로고
    • Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs
    • doi:10.1016/j.cell.2010.03.039. PubMed: 20478254
    • Krol J, Busskamp V, Markiewicz I, Stadler MB, Ribi S et al. (2010) Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs. Cell 141: 618-631. doi:10.1016/j.cell. 2010.03.039. PubMed: 20478254.
    • (2010) Cell , vol.141 , pp. 618-631
    • Krol, J.1    Busskamp, V.2    Markiewicz, I.3    Stadler, M.B.4    Ribi, S.5
  • 17
    • 84870601009 scopus 로고    scopus 로고
    • Selective autophagy degrades DICER and AGO2 and regulates miRNA activity
    • doi:10.1038/ncb2611. PubMed: 23143396
    • Gibbings D, Mostowy S, Jay F, Schwab Y, Cossart P et al. (2012) Selective autophagy degrades DICER and AGO2 and regulates miRNA activity. Nat Cell Biol 14: 1314-1321. doi:10.1038/ncb2611. PubMed: 23143396.
    • (2012) Nat Cell Biol , vol.14 , pp. 1314-1321
    • Gibbings, D.1    Mostowy, S.2    Jay, F.3    Schwab, Y.4    Cossart, P.5
  • 18
    • 80052213072 scopus 로고    scopus 로고
    • Analysis of microRNA turnover in mammalian cells following Dicer1 ablation
    • doi:10.1093/nar/gkr148. PubMed: 21447562
    • Gantier MP, McCoy CE, Rusinova I, Saulep D, Wang D et al. (2011) Analysis of microRNA turnover in mammalian cells following Dicer1 ablation. Nucleic Acids Res 39: 5692-5703. doi:10.1093/nar/gkr148. PubMed: 21447562.
    • (2011) Nucleic Acids Res , vol.39 , pp. 5692-5703
    • Gantier, M.P.1    McCoy, C.E.2    Rusinova, I.3    Saulep, D.4    Wang, D.5
  • 19
    • 84863715734 scopus 로고    scopus 로고
    • Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects
    • doi:10.1038/nm.2834. PubMed: 22683779
    • Jimenez-Mateos EM, Engel T, Merino-Serrais P, McKiernan RC, Tanaka K et al. (2012) Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects. Nat Med 18: 1087-1094. doi:10.1038/nm.2834. PubMed: 22683779.
    • (2012) Nat Med , vol.18 , pp. 1087-1094
    • Jimenez-Mateos, E.M.1    Engel, T.2    Merino-Serrais, P.3    McKiernan, R.C.4    Tanaka, K.5
  • 20
    • 65849222556 scopus 로고    scopus 로고
    • Phase II open label study of valproic acid in spinal muscular atrophy
    • doi:10.1371/journal.pone.0005268. PubMed: 19440247
    • Swoboda KJ, Scott CB, Reyna SP, Prior TW, LaSalle B et al. (2009) Phase II open label study of valproic acid in spinal muscular atrophy. PLOS ONE 4: e5268. doi:10.1371/journal.pone.0005268. PubMed: 19440247.
    • (2009) PLOS ONE , vol.4
    • Swoboda, K.J.1    Scott, C.B.2    Reyna, S.P.3    Prior, T.W.4    LaSalle, B.5
  • 21
    • 84858983547 scopus 로고    scopus 로고
    • KEGG for integration and interpretation of large-scale molecular data sets
    • doi:10.1093/nar/gkr988. PubMed: 22080510
    • Kanehisa M, Goto S, Sato Y, Furumichi M, Tanabe M (2012) KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res 40: D109-D114. doi:10.1093/nar/gkr988. PubMed: 22080510.
    • (2012) Nucleic Acids Res , vol.40
    • Kanehisa, M.1    Goto, S.2    Sato, Y.3    Furumichi, M.4    Tanabe, M.5
  • 22
    • 33750221973 scopus 로고    scopus 로고
    • Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells
    • doi:10.1093/nar/gkl646. PubMed: 16971455
    • Schmitter D, Filkowski J, Sewer A, Pillai RS, Oakeley EJ et al. (2006) Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells. Nucleic Acids Res 34: 4801-4815. doi:10.1093/nar/gkl646. PubMed: 16971455.
    • (2006) Nucleic Acids Res , vol.34 , pp. 4801-4815
    • Schmitter, D.1    Filkowski, J.2    Sewer, A.3    Pillai, R.S.4    Oakeley, E.J.5
  • 23
    • 32544453192 scopus 로고    scopus 로고
    • Every-12-hour administration of extended-release divalproex in patients with epilepsy: Impact on plasma valproic acid concentrations
    • Reed RC, Dutta S, Cavanaugh JH, Locke C, Granneman GR (2006) Every-12-hour administration of extended-release divalproex in patients with epilepsy: impact on plasma valproic acid concentrations. Epilepsy & behavior. E&B 8: 391-396.
    • (2006) Epilepsy & Behavior. E&B , vol.8 , pp. 391-396
    • Reed, R.C.1    Dutta, S.2    Cavanaugh, J.H.3    Locke, C.4    Granneman, G.R.5
  • 24
    • 0033621047 scopus 로고    scopus 로고
    • Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity
    • doi:10.1073/pnas.96.18.10403. PubMed: 10468620
    • Meng L, Mohan R, Kwok BH, Elofsson M, Sin N et al. (1999) Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. Proc Natl Acad Sci U S A 96: 10403-10408. doi:10.1073/pnas.96.18. 10403. PubMed: 10468620.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 10403-10408
    • Meng, L.1    Mohan, R.2    Kwok, B.H.3    Elofsson, M.4    Sin, N.5
  • 25
    • 0025925091 scopus 로고
    • Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells
    • PubMed: 1832676
    • Yoshimori T, Yamamoto A, Moriyama Y, Futai M, Tashiro Y (1991) Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. J Biol Chem 266: 17707-17712. PubMed: 1832676.
    • (1991) J Biol Chem , vol.266 , pp. 17707-17712
    • Yoshimori, T.1    Yamamoto, A.2    Moriyama, Y.3    Futai, M.4    Tashiro, Y.5
  • 26
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • PubMed: 17611390
    • Mizushima N, Yoshimori T (2007) How to interpret LC3 immunoblotting. Autophagy 3: 542-545. PubMed: 17611390.
    • (2007) Autophagy , vol.3 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 27
    • 13844294261 scopus 로고    scopus 로고
    • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
    • doi:10.1101/gad.1248505. PubMed: 15713842
    • Kanellopoulou C, Muljo SA, Kung AL, Ganesan S, Drapkin R et al. (2005) Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev 19: 489-501. doi:10.1101/gad.1248505. PubMed: 15713842.
    • (2005) Genes Dev , vol.19 , pp. 489-501
    • Kanellopoulou, C.1    Muljo, S.A.2    Kung, A.L.3    Ganesan, S.4    Drapkin, R.5
  • 28
    • 77953897182 scopus 로고    scopus 로고
    • A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity
    • doi:10.1126/science.1190809. PubMed: 20448148
    • Cifuentes D, Xue H, Taylor DW, Patnode H, Mishima Y et al. (2010) A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science 328: 1694-1698. doi:10.1126/science.1190809. PubMed: 20448148.
    • (2010) Science , vol.328 , pp. 1694-1698
    • Cifuentes, D.1    Xue, H.2    Taylor, D.W.3    Patnode, H.4    Mishima, Y.5
  • 29
    • 77953566255 scopus 로고    scopus 로고
    • miR-129 regulates cell proliferation by downregulating Cdk6 expression
    • doi:10.4161/cc.9.9.11535. PubMed: 20404570
    • Wu J, Qian J, Li C, Kwok L, Cheng F et al. (2010) miR-129 regulates cell proliferation by downregulating Cdk6 expression. Cell Cycle 9: 1809-1818. doi:10.4161/cc.9.9.11535. PubMed: 20404570.
    • (2010) Cell Cycle , vol.9 , pp. 1809-1818
    • Wu, J.1    Qian, J.2    Li, C.3    Kwok, L.4    Cheng, F.5
  • 30
    • 67649634849 scopus 로고    scopus 로고
    • Defining the human deubiquitinating enzyme interaction landscape
    • doi:10.1016/j.cell.2009.04.042. PubMed: 19615732
    • Sowa ME, Bennett EJ, Gygi SP, Harper JW (2009) Defining the human deubiquitinating enzyme interaction landscape. Cell 138: 389-403. doi:10.1016/j.cell.2009.04.042. PubMed: 19615732.
    • (2009) Cell , vol.138 , pp. 389-403
    • Sowa, M.E.1    Bennett, E.J.2    Gygi, S.P.3    Harper, J.W.4
  • 31
    • 79960147502 scopus 로고    scopus 로고
    • Exosome isolation for proteomic analyses and RNA profiling
    • doi:10.1007/978-1-61779-068-3-15. PubMed: 21468952
    • Taylor DD, Zacharias W, Gercel-Taylor C (2011) Exosome isolation for proteomic analyses and RNA profiling. Methods Mol Biol 728: 235-246. doi:10.1007/978-1-61779-068-3-15. PubMed: 21468952.
    • (2011) Methods Mol Biol , vol.728 , pp. 235-246
    • Taylor, D.D.1    Zacharias, W.2    Gercel-Taylor, C.3
  • 32
    • 52949113864 scopus 로고    scopus 로고
    • Deletion of Dicer in somatic cells of the female reproductive tract causes sterility
    • doi:10.1210/me.2008-0142. PubMed: 18687735
    • Nagaraja AK, Andreu-Vieyra C, Franco HL, Ma L, Chen R et al. (2008) Deletion of Dicer in somatic cells of the female reproductive tract causes sterility. Mol Endocrinol 22: 2336-2352. doi:10.1210/me.2008-0142. PubMed: 18687735.
    • (2008) Mol Endocrinol , vol.22 , pp. 2336-2352
    • Nagaraja, A.K.1    Andreu-Vieyra, C.2    Franco, H.L.3    Ma, L.4    Chen, R.5
  • 33
    • 41149147013 scopus 로고    scopus 로고
    • Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
    • doi:10.1073/pnas.0710228105. PubMed: 18256189
    • Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M et al. (2008) Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A 105: 2111-2116. doi:10.1073/pnas. 0710228105. PubMed: 18256189.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2111-2116
    • Chen, J.F.1    Murchison, E.P.2    Tang, R.3    Callis, T.E.4    Tatsuguchi, M.5
  • 34
    • 84864464973 scopus 로고    scopus 로고
    • DIANA miRPath v.2.0: Investigating the combinatorial effect of microRNAs in pathways
    • doi:10.1093/nar/gks494. PubMed: 22649059
    • Vlachos IS, Kostoulas N, Vergoulis T, Georgakilas G, Reczko M et al. (2012) DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways. Nucleic Acids Res 40: W498-W504. doi:10.1093/nar/gks494. PubMed: 22649059.
    • (2012) Nucleic Acids Res , vol.40
    • Vlachos, I.S.1    Kostoulas, N.2    Vergoulis, T.3    Georgakilas, G.4    Reczko, M.5
  • 35
    • 84873263700 scopus 로고    scopus 로고
    • Evaluation of melanogenesis in A-375 melanoma cells treated with 5,7-dimethoxycoumarin and valproic acid
    • PubMed: 23001511
    • Chodurek E, Orchel A, Orchel J, Kurkiewicz S, Gawlik N et al. (2012) Evaluation of melanogenesis in A-375 melanoma cells treated with 5,7-dimethoxycoumarin and valproic acid. Cell Mol Biol Lett 17: 616-632. PubMed: 23001511.
    • (2012) Cell Mol Biol Lett , vol.17 , pp. 616-632
    • Chodurek, E.1    Orchel, A.2    Orchel, J.3    Kurkiewicz, S.4    Gawlik, N.5
  • 36
    • 44949139634 scopus 로고    scopus 로고
    • Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina
    • doi:10.1523/JNEUROSCI.0828-08.2008. PubMed: 18463241
    • Damiani D, Alexander JJ, O'Rourke JR, McManus M, Jadhav AP et al. (2008) Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci 28: 4878-4887. doi:10.1523/JNEUROSCI.0828-08. 2008. PubMed: 18463241.
    • (2008) J Neurosci , vol.28 , pp. 4878-4887
    • Damiani, D.1    Alexander, J.J.2    O'Rourke, J.R.3    McManus, M.4    Jadhav, A.P.5
  • 37
    • 33748166945 scopus 로고    scopus 로고
    • Does it really matter when a blood sample for valproic acid concentration is taken following once-daily administration of divalproex-ER?
    • doi:10.1097/01.ftd.0000211814.12311.3f. PubMed: 16778728
    • Reed RC, Dutta S (2006) Does it really matter when a blood sample for valproic acid concentration is taken following once-daily administration of divalproex-ER? Ther Drug Monit 28: 413-418. doi:10.1097/01.ftd.0000211814.12311. 3f. PubMed: 16778728.
    • (2006) Ther Drug Monit , vol.28 , pp. 413-418
    • Reed, R.C.1    Dutta, S.2
  • 38
    • 57349111762 scopus 로고    scopus 로고
    • Downregulation of Dicer expression by serum withdrawal sensitizes human endothelial cells to apoptosis
    • doi:10.1152/ajpheart.00233.2008. PubMed: 18978195
    • Asada S, Takahashi T, Isodono K, Adachi A, Imoto H et al. (2008) Downregulation of Dicer expression by serum withdrawal sensitizes human endothelial cells to apoptosis. Am J Physiol Heart Circ Physiol 295: H2512-H2521. doi:10.1152/ajpheart.00233.2008. PubMed: 18978195.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Asada, S.1    Takahashi, T.2    Isodono, K.3    Adachi, A.4    Imoto, H.5
  • 39
    • 60949102130 scopus 로고    scopus 로고
    • Dicer is regulated by cellular stresses and interferons
    • doi:10.1016/j.molimm.2008.11.012. PubMed: 19118902
    • Wiesen JL, Tomasi TB (2009) Dicer is regulated by cellular stresses and interferons. Mol Immunol 46: 1222-1228. doi:10.1016/j.molimm.2008.11.012. PubMed: 19118902.
    • (2009) Mol Immunol , vol.46 , pp. 1222-1228
    • Wiesen, J.L.1    Tomasi, T.B.2
  • 40
    • 79952786337 scopus 로고    scopus 로고
    • DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
    • doi:10.1038/nature09830. PubMed: 21297615
    • Kaneko H, Dridi S, Tarallo V, Gelfand BD, Fowler BJ et al. (2011) DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature 471: 325-330. doi:10.1038/nature09830. PubMed: 21297615.
    • (2011) Nature , vol.471 , pp. 325-330
    • Kaneko, H.1    Dridi, S.2    Tarallo, V.3    Gelfand, B.D.4    Fowler, B.J.5
  • 41
    • 84866157204 scopus 로고    scopus 로고
    • Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis
    • doi:10.1371/journal.pone.0035921. PubMed: 22615744
    • McKiernan RC, Jimenez-Mateos EM, Bray I, Engel T, Brennan GP et al. (2012) Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis. PLOS ONE 7: e35921. doi:10.1371/journal.pone.0035921. PubMed: 22615744.
    • (2012) PLOS ONE , vol.7
    • McKiernan, R.C.1    Jimenez-Mateos, E.M.2    Bray, I.3    Engel, T.4    Brennan, G.P.5
  • 42
    • 57249116888 scopus 로고    scopus 로고
    • Cross-hybridization modeling on Affymetrix exon arrays
    • doi:10.1093/bioinformatics/btn571. PubMed: 18984598
    • Kapur K, Jiang H, Xing Y, Wong WH (2008) Cross-hybridization modeling on Affymetrix exon arrays. Bioinformatics 24: 2887-2893. doi:10.1093/ bioinformatics/btn571. PubMed: 18984598.
    • (2008) Bioinformatics , vol.24 , pp. 2887-2893
    • Kapur, K.1    Jiang, H.2    Xing, Y.3    Wong, W.H.4
  • 43
    • 77950490438 scopus 로고    scopus 로고
    • MADS+: Discovery of differential splicing events from Affymetrix exon junction array data
    • doi:10.1093/bioinformatics/btp643. PubMed: 19933160
    • Shen S, Warzecha CC, Carstens RP, Xing Y (2010) MADS+: discovery of differential splicing events from Affymetrix exon junction array data. Bioinformatics 26: 268-269. doi:10.1093/bioinformatics/btp643. PubMed: 19933160.
    • (2010) Bioinformatics , vol.26 , pp. 268-269
    • Shen, S.1    Warzecha, C.C.2    Carstens, R.P.3    Xing, Y.4
  • 44
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • PubMed: 19131956
    • Huang da W, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57. PubMed: 19131956.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 45
    • 0033760404 scopus 로고    scopus 로고
    • Pediatric rhabdomyosarcoma cell lines are resistant to Fas-induced apoptosis and highly sensitive to TRAIL-induced apoptosis
    • PubMed: 11051265
    • Petak I, Douglas L, Tillman DM, Vernes R, Houghton JA (2000) Pediatric rhabdomyosarcoma cell lines are resistant to Fas-induced apoptosis and highly sensitive to TRAIL-induced apoptosis. Clin Cancer Res 6: 4119-4127. PubMed: 11051265.
    • (2000) Clin Cancer Res , vol.6 , pp. 4119-4127
    • Petak, I.1    Douglas, L.2    Tillman, D.M.3    Vernes, R.4    Houghton, J.A.5
  • 46
    • 37549002103 scopus 로고    scopus 로고
    • Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processing
    • PubMed: 17913700
    • Novoyatleva T, Heinrich B, Tang Y, Benderska N, Butchbach ME et al. (2008) Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processing. Hum Mol Genet, 17: 52-70. PubMed: 17913700.
    • (2008) Hum Mol Genet , vol.17 , pp. 52-70
    • Novoyatleva, T.1    Heinrich, B.2    Tang, Y.3    Benderska, N.4    Butchbach, M.E.5
  • 47
    • 77952473473 scopus 로고    scopus 로고
    • The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing
    • doi:10.1093/hmg/ddp585. PubMed: 20053671
    • Kishore S, Khanna A, Zhang Z, Hui J, Balwierz PJ et al. (2010) The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing. Hum Mol Genet 19: 1153-1164. doi:10.1093/hmg/ddp585. PubMed: 20053671.
    • (2010) Hum Mol Genet , vol.19 , pp. 1153-1164
    • Kishore, S.1    Khanna, A.2    Zhang, Z.3    Hui, J.4    Balwierz, P.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.