Guanylate Cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Harmel Laws, Eleana ^b   Mann, Elizabeth A ^b   Cohen, Mitchell B ^a,b   Steinbrecher, Kris A ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANYLATE CYCLASE; GUANYLATE CYCLASE C; GUANYLIN; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL STRAIN HT29; COLITIS; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME DEFICIENCY; ENZYME SYNTHESIS; GENE DELETION; GENE REPRESSION; GUANYLATE CYCLASE C DEFICIENCY; GUANYLIN GENE; IMMUNE RESPONSE; IMMUNOREGULATION; IN VIVO STUDY; INFLAMMATION; INTESTINE EPITHELIUM CELL; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; COLITIS; GASTROINTESTINAL HORMONES; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-10; INTESTINAL MUCOSA; MICE; MICE, KNOCKOUT; MUTATION; NATRIURETIC PEPTIDES; RECEPTORS, GUANYLATE CYCLASE-COUPLED; RECEPTORS, PEPTIDE; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84892906452     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079180     Document Type: Article

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