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Volumn 303, Issue 2, 2012, Pages

Type 2 cGMP-dependent protein Kinase regulates proliferation and differentiation in the colonic mucosa

Author keywords

cGMP; Muc2; Prkg2; Sox9

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE 2; MUCIN 2; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR SOX9;

EID: 84863908095     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00500.2011     Document Type: Article
Times cited : (39)

References (49)
  • 2
    • 3142669010 scopus 로고    scopus 로고
    • SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes
    • Blache P, van de Wetering M, Duluc I, Domon C, Berta P, Freund JN, Clevers H, Jay P. SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes. J Cell Biol 166: 37-47, 2004.
    • (2004) J Cell Biol , vol.166 , pp. 37-47
    • Blache, P.1    van de Wetering, M.2    Duluc, I.3    Domon, C.4    Berta, P.5    Freund, J.N.6    Clevers, H.7    Jay, P.8
  • 3
    • 77953462071 scopus 로고    scopus 로고
    • The cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment
    • Browning D, Kwon IK, Wang R. The cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment. Future Med Chem 2: 15-20, 2010.
    • (2010) Future Med Chem , vol.2 , pp. 15-20
    • Browning, D.1    Kwon, I.K.2    Wang, R.3
  • 4
    • 41049095471 scopus 로고    scopus 로고
    • Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer
    • Browning DD. Protein kinase G as a therapeutic target for the treatment of metastatic colorectal cancer. Expert Opin Ther Targets 12: 367-376, 2008.
    • (2008) Expert Opin Ther Targets , vol.12 , pp. 367-376
    • Browning, D.D.1
  • 6
    • 78650538188 scopus 로고    scopus 로고
    • The role of CDX2 in intestinal homeostasis and inflammation
    • Coskun M, Troelsen JT, Nielsen OH. The role of CDX2 in intestinal homeostasis and inflammation. Biochim Biophys Acta 1812: 283-289, 2011.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 283-289
    • Coskun, M.1    Troelsen, J.T.2    Nielsen, O.H.3
  • 8
    • 7044269199 scopus 로고    scopus 로고
    • Uroguanylin and guanylin peptides: Pharmacology and experimental therapeutics
    • Forte LR Jr. Uroguanylin and guanylin peptides: pharmacology and experimental therapeutics. Pharmacol Ther 104: 137-162, 2004.
    • (2004) Pharmacol Ther , vol.104 , pp. 137-162
    • Forte Jr., L.R.1
  • 12
    • 33644834949 scopus 로고    scopus 로고
    • Function of cGMPdependent protein kinases as revealed by gene deletion
    • Hofmann F, Feil R, Kleppisch T, Schlossmann J. Function of cGMPdependent protein kinases as revealed by gene deletion. Physiol Rev 86: 1-23, 2006.
    • (2006) Physiol Rev , vol.86 , pp. 1-23
    • Hofmann, F.1    Feil, R.2    Kleppisch, T.3    Schlossmann, J.4
  • 14
    • 84857120620 scopus 로고    scopus 로고
    • Cdx function is required for maintenance of intestinal identity in the adult
    • Hryniuk A, Grainger S, Savory JG, Lohnes D. Cdx function is required for maintenance of intestinal identity in the adult. Dev Biol 363: 426-437, 2012.
    • (2012) Dev Biol , vol.363 , pp. 426-437
    • Hryniuk, A.1    Grainger, S.2    Savory, J.G.3    Lohnes, D.4
  • 17
    • 41149096647 scopus 로고    scopus 로고
    • Expression of cyclic guanosine monophosphate-dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesis
    • Kwon IK, Schoenlein PV, Delk J, Liu K, Thangaraju M, Dulin NO, Ganapathy V, Berger FG, Browning DD. Expression of cyclic guanosine monophosphate-dependent protein kinase in metastatic colon carcinoma cells blocks tumor angiogenesis. Cancer 112: 1462-1470, 2008.
    • (2008) Cancer , vol.112 , pp. 1462-1470
    • Kwon, I.K.1    Schoenlein, P.V.2    Delk, J.3    Liu, K.4    Thangaraju, M.5    Dulin, N.O.6    Ganapathy, V.7    Berger, F.G.8    Browning, D.D.9
  • 18
  • 20
    • 38349041719 scopus 로고    scopus 로고
    • Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine
    • Li P, Lin JE, Chervoneva I, Schulz S, Waldman SA, Pitari GM. Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine. Am J Pathol 171: 1847-1858, 2007.
    • (2007) Am J Pathol , vol.171 , pp. 1847-1858
    • Li, P.1    Lin, J.E.2    Chervoneva, I.3    Schulz, S.4    Waldman, S.A.5    Pitari, G.M.6
  • 21
    • 77955869895 scopus 로고    scopus 로고
    • Can colorectal cancer be prevented or treated by oral hormone replacement therapy?
    • Li P, Lin JE, Schulz S, Pitari GM, Waldman SA. Can colorectal cancer be prevented or treated by oral hormone replacement therapy? Curr Mol Pharmacol 2: 285-292, 2009.
    • (2009) Curr Mol Pharmacol , vol.2 , pp. 285-292
    • Li, P.1    Lin, J.E.2    Schulz, S.3    Pitari, G.M.4    Waldman, S.A.5
  • 25
    • 0034862256 scopus 로고    scopus 로고
    • Invited review: CGMP-dependent protein kinase signaling mechanisms in smooth muscle: From the regulation of tone to gene expression
    • Lincoln TM, Dey N, Sellak H. Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression. J Appl Physiol 91: 1421-1430, 2001.
    • (2001) J Appl Physiol , vol.91 , pp. 1421-1430
    • Lincoln, T.M.1    Dey, N.2    Sellak, H.3
  • 28
    • 0029114468 scopus 로고
    • Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator
    • Markert T, Vaandrager AB, Gambaryan S, Pohler D, Hausler C, Walter U, De Jonge HR, Jarchau T, Lohmann SM. Endogenous expression of type II cGMP-dependent protein kinase mRNA and protein in rat intestine. Implications for cystic fibrosis transmembrane conductance regulator. J Clin Invest 96: 822-830, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 822-830
    • Markert, T.1    Vaandrager, A.B.2    Gambaryan, S.3    Pohler, D.4    Hausler, C.5    Walter, U.6    de Jonge, H.R.7    Jarchau, T.8    Lohmann, S.M.9
  • 29
    • 79959238013 scopus 로고    scopus 로고
    • Microenvironmental regulation of stem cells in intestinal homeostasis and cancer
    • Medema JP, Vermeulen L. Microenvironmental regulation of stem cells in intestinal homeostasis and cancer. Nature 474: 318-326, 2011.
    • (2011) Nature , vol.474 , pp. 318-326
    • Medema, J.P.1    Vermeulen, L.2
  • 31
    • 33846282337 scopus 로고    scopus 로고
    • Loss of MUC2 expression correlates with progression along the adenoma-carcinoma sequence pathway as well as de novo carcinogenesis in the colon
    • Mizoshita T, Tsukamoto T, Inada KI, Hirano N, Tajika M, Nakamura T, Ban H, Tatematsu M. Loss of MUC2 expression correlates with progression along the adenoma-carcinoma sequence pathway as well as de novo carcinogenesis in the colon. Histol Histopathol 22: 251-260, 2007.
    • (2007) Histol Histopathol , vol.22 , pp. 251-260
    • Mizoshita, T.1    Tsukamoto, T.2    Inada, K.I.3    Hirano, N.4    Tajika, M.5    Nakamura, T.6    Ban, H.7    Tatematsu, M.8
  • 32
    • 0030452310 scopus 로고    scopus 로고
    • Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II
    • Pfeifer A, Aszodi A, Seidler U, Ruth P, Hofmann F, Fassler R. Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II. Science 274: 2082-2086, 1996.
    • (1996) Science , vol.274 , pp. 2082-2086
    • Pfeifer, A.1    Aszodi, A.2    Seidler, U.3    Ruth, P.4    Hofmann, F.5    Fassler, R.6
  • 33
    • 28244432560 scopus 로고    scopus 로고
    • Interruption of homologous desensitization in cyclic guanosine 3',5'- monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins
    • Pitari GM, Baksh RI, Harris DM, Li P, Kazerounian S, Waldman SA. Interruption of homologous desensitization in cyclic guanosine 3',5'- monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins. Cancer Res 65: 11129-11135, 2005.
    • (2005) Cancer Res , vol.65 , pp. 11129-11135
    • Pitari, G.M.1    Baksh, R.I.2    Harris, D.M.3    Li, P.4    Kazerounian, S.5    Waldman, S.A.6
  • 34
    • 0034933794 scopus 로고    scopus 로고
    • Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells
    • Pitari GM, Di Guglielmo MD, Park J, Schulz S, Waldman SA. Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells. Proc Natl Acad Sci USA 98: 7846-7851, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7846-7851
    • Pitari, G.M.1    di Guglielmo, M.D.2    Park, J.3    Schulz, S.4    Waldman, S.A.5
  • 36
    • 75349108490 scopus 로고    scopus 로고
    • Probiotic-induced changes in the intestinal epithelium: Implications in gastrointestinal disease
    • Ramakrishna BS. Probiotic-induced changes in the intestinal epithelium: implications in gastrointestinal disease. Trop Gastroenterol 30: 76-85, 2009.
    • (2009) Trop Gastroenterol , vol.30 , pp. 76-85
    • Ramakrishna, B.S.1
  • 37
    • 44149087353 scopus 로고    scopus 로고
    • Downregulation of human colon carcinoma cell (COLO-205) proliferation through PKGMAP kinase mediated signaling cascade by E. coli heat stable enterotoxin (STa), a potent anti-angiogenic and anti-metastatic molecule
    • Saha S, Chowdhury P, Pal A, Chakrabarti MK. Downregulation of human colon carcinoma cell (COLO-205) proliferation through PKGMAP kinase mediated signaling cascade by E. coli heat stable enterotoxin (STa), a potent anti-angiogenic and anti-metastatic molecule. J Appl Toxicol 28: 475-483, 2008.
    • (2008) J Appl Toxicol , vol.28 , pp. 475-483
    • Saha, S.1    Chowdhury, P.2    Pal, A.3    Chakrabarti, M.K.4
  • 38
    • 39749092525 scopus 로고    scopus 로고
    • Current view: Intestinal stem cells and signaling
    • Scoville DH, Sato T, He XC, Li L. Current view: intestinal stem cells and signaling. Gastroenterology 134: 849-864, 2008.
    • (2008) Gastroenterology , vol.134 , pp. 849-864
    • Scoville, D.H.1    Sato, T.2    He, X.C.3    Li, L.4
  • 40
    • 80455174708 scopus 로고    scopus 로고
    • Stem cell self-renewal in intestinal crypt
    • Simons BD, Clevers H. Stem cell self-renewal in intestinal crypt. Exp Cell Res 317: 2719-2724, 2011.
    • (2011) Exp Cell Res , vol.317 , pp. 2719-2724
    • Simons, B.D.1    Clevers, H.2
  • 41
    • 79951681078 scopus 로고    scopus 로고
    • Transmembrane guanylate cyclase in intestinal pathophysiology
    • Steinbrecher KA, Cohen MB. Transmembrane guanylate cyclase in intestinal pathophysiology. Curr Opin Gastroenterol 27: 139-145, 2011.
    • (2011) Curr Opin Gastroenterol , vol.27 , pp. 139-145
    • Steinbrecher, K.A.1    Cohen, M.B.2
  • 43
    • 0036898023 scopus 로고    scopus 로고
    • Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation
    • Steinbrecher KA, Wowk SA, Rudolph JA, Witte DP, Cohen MB. Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation. Am J Pathol 161: 2169-2178, 2002.
    • (2002) Am J Pathol , vol.161 , pp. 2169-2178
    • Steinbrecher, K.A.1    Wowk, S.A.2    Rudolph, J.A.3    Witte, D.P.4    Cohen, M.B.5
  • 44
    • 69849089410 scopus 로고    scopus 로고
    • Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines
    • Swartling FJ, Ferletta M, Kastemar M, Weiss WA, Westermark B. Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. Oncogene 28: 3121-3131, 2009.
    • (2009) Oncogene , vol.28 , pp. 3121-3131
    • Swartling, F.J.1    Ferletta, M.2    Kastemar, M.3    Weiss, W.A.4    Westermark, B.5
  • 47
    • 80053573152 scopus 로고    scopus 로고
    • Enterocyte death and intestinal barrier maintenance in homeostasis and disease
    • Vereecke L, Beyaert R, van Loo G. Enterocyte death and intestinal barrier maintenance in homeostasis and disease. Trends Mol Med 17: 584-593, 2011.
    • (2011) Trends Mol Med , vol.17 , pp. 584-593
    • Vereecke, L.1    Beyaert, R.2    van Loo, G.3
  • 49
    • 0037462878 scopus 로고    scopus 로고
    • Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression
    • Yamamoto H, Bai YQ, Yuasa Y. Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression. Biochem Biophys Res Commun 300: 813-818, 2003.
    • (2003) Biochem Biophys Res Commun , vol.300 , pp. 813-818
    • Yamamoto, H.1    Bai, Y.Q.2    Yuasa, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.