Generation of precise point mutation mice by footprintless genome modification

Genesis

Volumn 52, Issue 1, 2014, Pages 68-77

  Morioka, Yuka ^a   Fujihara, Yoshitaka ^b   Okabe, Masaru ^b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

BAC recombineering; PiggyBac transposon; Wv mutation

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CONTROLLED STUDY; DNA MODIFICATION; GENE TARGETING; GENETIC RECOMBINATION; GENOME; MOUSE; NONHUMAN; PLASMID; POINT MUTATION; PRIORITY JOURNAL; TRANSGENE; TRANSPOSON;

MUS;

BAC RECOMBINEERING; PIGGYBAC TRANSPOSON; WV MUTATION;

ANIMALS; DISEASE MODELS, ANIMAL; DNA TRANSPOSABLE ELEMENTS; FEMALE; GENOME; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; POINT MUTATION; PROTO-ONCOGENE PROTEINS C-KIT;

EID: 84892839792     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.22727     Document Type: Article

References (29)

1. Branda CS, Dymecki SM. 2004. Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice. Dev Cell 6:7-28.
2. Cadinanos J, Bradley A. 2007. Generation of an inducible and optimized piggyBac transposon system. Nucleic Acids Res 35:e87.
3. Cary LC, Goebel M, Corsaro BG, Wang HG, Rosen E, Fraser MJ. 1989. Transposon mutagenesis of baculoviruses: Analysis of Trichoplusia ni transposon IFP2 insertions within the FP-locus of nuclear polyhedrosis viruses. Virology 172:156-169.
4. Chen YT, Bradley A. 2000. A new positive/negative selectable marker, puDeltatk, for use in embryonic stem cells. Genesis 28:31-35.
5. Chuma S, Nakatsuji N. 2001. Autonomous transition into meiosis of mouse fetal germ cells in vitro and its inhibition by gp130-mediated signaling. Dev Biol 229:468-479.
6. Copeland NG, Jenkins NA, Court DL. 2001. Recombineering: A powerful new tool for mouse functional genomics. Nat Rev Genet 2:769-779.
7. Ding S, Wu X, Li G, Han M, Zhuang Y, Xu T. 2005. Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell 122:473-483.
8. Fraser MJ, Ciszczon T, Elick T, Bauser C. 1996. Precise excision of TTAA-specific lepidopteran transposons piggyBac (IFP2) and tagalong (TFP3) from the baculovirus genome in cell lines from two species of Lepidoptera. Insect Mol Biol 5:141-151.
9. Fujihara Y, Kaseda K, Inoue N, Ikawa M, Okabe M. 2013. Production of mouse pups from germline transmission-failed knockout chimeras. Transgenic Res 22:195-200.
10. Gondo Y, Fukumura R, Murata T, Makino S. 2010. ENU-based gene-driven mutagenesis in the mouse: A next-generation gene-targeting system. Exp Anim 59:537-548.
11. Ho Y, Wigglesworth K, Eppig JJ, Schultz RM. 1995. Preimplantation development of mouse embryos in KSOM: Augmentation by amino acids and analysis of gene expression. Mol Reprod Dev 41:232-238.
12. Hrabe de Angelis MH, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, Marschall S, Heffner S, Pargent W, Wuensch K, Jung M, Reis A, Richter T, Alessandrini F, Jakob T, Fuchs E, Kolb H, Kremmer E, Schaeble K, Rollinski B, Roscher A, Peters C, Meitinger T, Strom T, Steckler T, Holsboer F, Klopstock T, Gekeler F, Schindewolf C, Jung T, Avraham K, Behrendt H, Ring J, Zimmer A, Schughart K, Pfeffer K, Wolf E, Balling R. 2000. Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet 25:444-447.
13. Ikawa M, Wada I, Kominami K, Watanabe D, Toshimori K, Nishimune Y, Okabe M. 1997. The putative chaperone calmegin is required for sperm fertility. Nature 387: 607-611.
14. Li MZ, Elledge SJ. 2005. MAGIC, an in vivo genetic method for the rapid construction of recombinant DNA molecules. Nat Genet 37:311-319.
15. Meier ID, Bernreuther C, Tilling T, Neidhardt J, Wong YW, Schulze C, Streichert T, Schachner M. 2010. Short DNA sequences inserted for gene targeting can accidentally interfere with off-target gene expression. FASEB J 24:1714-1724.
16. Nagy A, Gertsenstein M, Vintersten K, Behringer R. 2003. Manipulating the mouse embryo: A laboratory manual. NY, USA: Cold Spring Harbor Laboratory Press.
17. Nakanishi T, Ikawa M, Yamada S, Toshimori K, Okabe M. 2001. Alkalinization of acrosome measured by GFP as a pH indicator and its relation to sperm capacitation. Dev Biol 237:222-231.
18. Nicolson GL, Yanagimachi R, Yanagimachi H. 1975. Ultrastructural localization of lectin-binding sites on the zonae pellucidae and plasma membranes of mammalian eggs. J Cell Biol 66:263-274.
19. Nocka K, Tan JC, Chiu E, Chu TY, Ray P, Traktman P, Besmer P. 1990. Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W. EMBO J 9:1805-1813.
20. Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC, Vizor L, Brooker D, Whitehill E, Washbourne R, Hough T, Greenaway S, Hewitt M, Liu X, McCormack S, Pickford K, Selley R, Wells C, Tymowska-Lalanne Z, Roby P, Glenister P, Thornton C, Thaung C, Stevenson JA, Arkell R, Mburu P, Hardisty R, Kiernan A, Erven A, Steel KP, Voegeling S, Guenet JL, Nickols C, Sadri R, Nasse M, Isaacs A, Davies K, Browne M, Fisher EM, Martin J, Rastan S, Brown SD, Hunter J. 2000. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet 25:440-443.
21. Okabe M, Ikawa M, Kominami K, Nakanishi T, Nishimune Y. 1997. 'Green mice' as a source of ubiquitous green cells. FEBS Lett 407:313-319.
22. Testa G, Vintersten K, Zhang Y, Benes V, Muyrers JP, Stewart AF. 2004. BAC engineering for the generation of ES cell-targeting constructs and mouse transgenes. Methods Mol Biol 256:123-139.
23. Tsujimura T, Koshimizu U, Katoh H, Isozaki K, Kanakura Y, Tono T, Adachi S, Kasugai T, Tei H, Nishimune Y, et al. 1993. Mast cell number in the skin of heterozygotes reflects the molecular nature of c-kit mutation. Blood 81:2530-2538.
24. van der Weyden L, Adams DJ, Bradley A. 2002. Tools for targeted manipulation of the mouse genome. Physiol Genomics 11:133-164.
25. Wang HG, Fraser MJ. 1993. TTAA serves as the target site for TFP3 lepidopteran transposon insertions in both nuclear polyhedrosis virus and Trichoplusia ni genomes. Insect Mol Biol 1:109-116.
26. Wang W, Lin C, Lu D, Ning Z, Cox T, Melvin D, Wang X, Bradley A, Liu P. 2008. Chromosomal transposition of PiggyBac in mouse embryonic stem cells. Proc Natl Acad Sci U S A 105:9290-9295.
27. Yusa K, Rad R, Takeda J, Bradley A. 2009. Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon. Nat Methods 6:363-369.
28. Yusa K, Rashid ST, Strick-Marchand H, Varela I, Liu PQ, Paschon DE, Miranda E, Ordonez A, Hannan NR, Rouhani FJ, Darche S, Alexander G, Marciniak SJ, Fusaki N, Hasegawa M, Holmes MC, Di Santo JP, Lomas DA, Bradley A, Vallier L. 2011. Targeted gene correction of alpha1-antitrypsin deficiency in induced pluripotent stem cells. Nature 478:391-394.
29. Zhang P, Li MZ, Elledge SJ. 2002. Towards genetic genome projects: Genomic library screening and gene-targeting vector construction in a single step. Nat Genet 30:31-39.