Beneficial effect of betulinic acid on hyperglycemia via suppression of hepatic glucose production

Journal of Agricultural and Food Chemistry

Volumn 62, Issue 2, 2014, Pages 434-442

  Kim, Soo Jung ^a   Quan, Hai Yan ^a   Jeong, Kyong Ju ^a   Kim, Do Yeon ^a   Kim, Go Woon ^a   Jo, Hee Kyung ^a   Chung, Sung Hyun ^a  

^a Kyung Hee University   (South Korea)

Author keywords

AMPK; betulinic acid; CREB; hepatic glucose production; type 2 diabetes

Indexed keywords

AMPK; BETULINIC ACID; CREB; GLUCOSE PRODUCTION; TYPE-2 DIABETES;

GENE EXPRESSION; MAMMALS; PHOSPHORYLATION;

GLUCOSE;

ANTIDIABETIC AGENT; BETULIC ACID; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; CREB1 PROTEIN, HUMAN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ENZYME INHIBITOR; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; TRITERPENE;

ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DIABETES MELLITUS, TYPE 2; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION; GENETICS; GLUCONEOGENESIS; HEPG2 CELL LINE; HUMAN; HYPERGLYCEMIA; INSTITUTE FOR CANCER RESEARCH MOUSE; LIPID DIET; LIVER; METABOLISM; MOUSE; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION; GLUCONEOGENESIS; GLUCOSE; HEP G2 CELLS; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; LIVER; MICE; MICE, INBRED ICR; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRITERPENES;

ANIMALIA; MUS;

EID: 84892736281     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf4030739     Document Type: Article

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