Factors influencing recruitment to research: Qualitative study of the experiences and perceptions of research teams

BMC Medical Research Methodology

Volumn 14, Issue 1, 2014, Pages

  Newington, Lisa ^a   Metcalfe, Alison ^b  

^a GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Clinical research; Participant recruitment; Qualitative

Indexed keywords

ARTICLE; CLINICAL TRIAL (TOPIC); HEALTH PERSONNEL ATTITUDE; HUMAN; MEDICAL RESEARCH; PATIENT SELECTION;

ATTITUDE OF HEALTH PERSONNEL; BIOMEDICAL RESEARCH; CLINICAL TRIALS AS TOPIC; HUMANS; PATIENT SELECTION;

EID: 84892703106     PISSN: None     EISSN: 14712288     Source Type: Journal    
DOI: 10.1186/1471-2288-14-10     Document Type: Article

References (35)

1. What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies. McDonald AM, Knight RC, Campbell MK, Entwistle VA, Grant AM, Cook JA, Elbourne DR, Francis D, Garcia J, Roberts I, et al. Trials 2006 7 9 10.1186/1745-6215-7-9 16603070 (Pubitemid 43862982)
2. Equity and Excellence: Liberating the NHS. http://www.gov.uk/government/ publications/liberating-the-nhs-white-paper
3. Methods to improve recruitment to randomised controlled trials: Cochrane systematic review and meta-analysis. Treweek S, Lockhart P, Pitkethly M, Cook JA, Kjeldstrøm M, Johansen M, Taskila TK, Sullivan FM, Wilson S, Jackson C, et al. BMJ Open 2013 3 002360 23396504
4. Women's Health Australia: recruitment for a National Longitudinal Cohort Study. Brown WJ, Bryson L, Byles JE, Dobson AJ, Lee C, Mishra G, Schofield M, Women Health 1999 28 1 23 40 10.1300/J013v28n01-03
5. Recruitment and retention of African American elders into community-based research: lessons learned. Dennis BP, Neese JB, Arch Psychiatr Nurs 2000 14 1 3 11 10.1016/S0883-9417(00)80003-5 10692801
6. Identifying, recruiting, and retaining seriously-ill patients and their caregivers in longitudinal research. Steinhauser KE, Clipp EC, Hays JC, Olsen M, Arnold R, Christakis NA, Lindquist JH, Tulsky JA, Palliat Med 2006 20 8 745 754 10.1177/0269216306073112 17148529 (Pubitemid 46040126)
7. Improving recruitment and retention rates in preventive longitudinal research with adolescent mothers. Seed M, Juarez M, Alnatour R, J Child Adolesc Psychiatr Nurs 2009 22 3 150 153 10.1111/j.1744-6171.2009.00193.x 19702968
8. Effective recruitment and retention of minority research participants. Yancey AK, Ortega AN, Kumanyika SK, Annu Rev Public Health 2006 27 1 1 28 10.1146/annurev.publhealth.27.021405.102113 16533107
9. Researchers' and clinicians' perceptions of recruiting participants to clinical research: a thematic meta-synthesis. Newington L, Metcalfe A, J Clin Med Res 2013 In Press
10. Why patients don't take part in cancer clinical trials: an overview of the literature. Cox K, McGarry J, Eur J Cancer Care (Engl) 2003 12 2 114 122 10.1046/j.1365-2354.2003.00396.x 12787008 (Pubitemid 37260163)
11. Predictors of refusal during a multi-step recruitment process for a randomized controlled trial of arthritis education. Blanch DC, Rudd RE, Wright E, Gall V, Katz JN, Patient Educ Couns 2008 73 2 280 285 10.1016/j.pec.2008.06. 017 18715740
12. Ethical aspects of clinical trials: the attitudes of participants in two non-cancer trials. Madsen SM, Holm S, Davidsen B, Munkholm P, Schlichting P, Riis P, J Intern Med 2000 248 6 463 474 10.1046/j.1365-2796.2000.00755.x 11155139 (Pubitemid 32052002)
13. Determinants of patient participation in clinical studies requiring informed consent: Why patients enter a clinical trial. Verheggen FWSM, Nieman F, Jonkers R, Patient Educ Couns 1998 35 2 111 125 10.1016/S0738-3991(98)00060-3 10026554 (Pubitemid 28412668)
14. Focus groups as an intervention for low-income African-American smokers to promote participation in subsequent intervention studies. Webb MS, Res Nurs Health 2008 31 141 151 10.1002/nur.20239 18181136
15. Factors predicting recruitment to a UK wide primary care smoking cessation study (the ESCAPE trial). Gilbert H, Leurent B, Sutton S, Morris R, Alexis-Garsee C, Nazareth I, Fam Pract 2012 29 1 110 117 10.1093/fampra/cmr030 21624941
16. Recruitment to multicentre trials-lessons from UKCTOCS: descriptive study. Menon U, Gentry-Maharaj A, Ryan A, Sharma A, Burnell M, Hallett R, Lewis S, Lopez A, Godfrey K, Oram D, et al. BMJ 2008 337 2079 10.1136/bmj.a2079 19008269
17. Qualitative data analysis for applied policy research. Ritchie J, Spencer L, Analyzing Qualitative Data London: Routledge, Bryman A, Burgess RG, 1994 172 194
18. Successful recruitment to clinical trials: a phased approach to opening gates and building bridges. Patterson S, Mairs H, Borschmann R, BMC Med Res Methodol 2011 11 73 doi: 10.1186/1471-2288-11-73
19. Does it matter if clinicians recruiting for a trial don't understand what the trial is really about? Qualitative study of surgeons' experiences of participation in a pragmatic multi-centre RCT. Ziebland S, Featherstone K, Snowdon C, Barker K, Frost H, Fairbank J, Trials 2007 8 4 10.1186/1745-6215-8-4 17257440
20. The handbook to the NHS Constitution. http://www.gov.uk/government/ publications/the-nhs-constitution-for-england
21. Who can best recruit to randomized trials? Randomized trial comparing surgeons and nurses recruiting patients to a trial of treatments for localized prostate cancer (the ProtecT study). Donovan JL, Peters TJ, Noble S, Powell P, Gillatt D, Oliver SE, Lane JA, Neal DE, Hamdy FC, J Clin Epidemiol 2003 56 7 605 609 10.1016/S0895-4356(03)00083-0 12921927 (Pubitemid 36960175)
22. Reasons for accepting or declining to participate in randomized clinical trials for cancer therapy. Jenkins V, Fallowfied L, Br J Cancer 2000 82 11 1783 1788 10.1054/bjoc.2000.1142 10839291 (Pubitemid 30307389)
23. Attributes of researchers and their strategies to recruit minority poulations: results of a national survey. Quinn SC, Butler J III, Fryer CS, Garza MA, Kim KH, Ryan C, Thomas SB, Contemp Clin Trials 2012 33 1231 1237 10.1016/j.cct.2012.06.011 22771575
24. Recruitment of hispanic women to the women's health initiative: the case of Embajadoras in Arizona. Larkey LK, Staten LK, Ritenbaugh C, Hall RA, Buller DB, Bassford T, Altimari BR, Control Clin Trials 2002 23 3 289 298 10.1016/S0197-2456(02)00190-3 12057880 (Pubitemid 34621209)
25. Betwixt & between: peer recruiter proximity in community-based research. Bean S, Silva DS, Am J Bioeth 2010 10 3 18 19 10.1080/ 15265160903581783
26. Representative sampling, III: the current statistical literature. Kruskal W, Mosteller F, Int Stat Rev 1979 47 3 245 265 10.2307/1402647
27. Ethical aspects in placental perfusion studies: views of the researchers. Halkoaho A, Pietila AM, Vahakangas K, Placenta 2011 32 7 511 515 10.1016/j.placenta.2011.04.006 21524791
28. BioBanking-the holy grail of novel drug and diagnostic developments? Marko-Varga G, J Clin Bioinformatics 2011 1 1 14 10.1186/2043-9113-1-14
29. Blinding in clinical trials and other studies. Day SJ, Altman DG, BMJ 2000 321 7259 504 10.1136/bmj.321.7259.504 10948038 (Pubitemid 30623610)
30. Double-blind studies are not always optimum for evaluation of a novel therapy: The case of new anticoagulants. Büller HR, Halperin JL, Bounameaux H, Prins M, J Thromb Haemost 2008 6 2 227 229 18034770
31. - 2011 Census: QS204EW Main language (detailed), unitary authorities in Wales. (Release date 30 January 2013) [ http://www.ons.gov.uk/ons/datasets-and- tables/index.html ]
32. Are racial and ethnic minorities less willing to participate in health research? Wendler D, Kington R, Madans J, Van Wye G, Christ-Schmidt H, Pratt LA, Brawley OW, Gross CP, Emanuel E, PLoS Med 2005 3 2 19 16318411
33. The Tuskegee legacy project: willingness of minorities to participate in biomedical research. Katz RV, Kegeles S, Kressin NR, Green B, Wang M, James SA, Russell SL, Claudio C, J Health Care Poor Underserved 2006 17 4 698 715 10.1353/hpu.2006.0126 17242525 (Pubitemid 44952204)
34. Evaluating minority recruitment into clinical studies: how good are the data? Ness RB, Nelson DB, Kumanyika SK, Grisso JA, Ann Epidemiol 1997 7 7 472 478 10.1016/S1047-2797(97)00080-X 9349914 (Pubitemid 27459072)
35. Personal travel factsheet: commuting and business travel. [ http://www.gov.uk/government/uploads/system/uploads/attachment-data/file/49703/ Commuting-and-business-travel-factsheet-April-2011.pdf ]