Recruitment to multicentre trials - Lessons from UKCTOCS: Descriptive study

BMJ

Volumn 337, Issue 7681, 2008, Pages 1283-1286

  Menon, Usha ^a   Gentry Maharaj, Aleksandra ^a   Ryan, Andy ^a   Sharma, Aarti ^a   Burnell, Matthew ^a   Hallett, Rachel ^a   Lewis, Sara ^a   Lopez, Alberto ^b   Godfrey, Keith ^b   Oram, David ^c   Herod, Jonathan ^d   Williamson, Karin ^e   Seif, Mourad ^f   Scott, Ian ^g   Mould, Tim ^h   Woolas, Robert ⁱ   Murdoch, John ^j   Dobbs, Stephen ^k   Amso, Nazar ^l   Leeson, Simon ^m   Cruickshank, Derek ⁿ   McGuire, Ali ^o   Campbell, Stuart ^p   Fallowfield, Lesley ^q   Skates, Steve ^r   Parmar, Mahesh ^s   Jacobs, Ian ^a   more..

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^c ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^d LIVERPOOL WOMEN S HOSPITAL   (United Kingdom)

^e NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^f ST MARY S HOSPITAL   (United Kingdom)

^g DERBY CITY GENERAL HOSPITAL   (United Kingdom)

^h ROYAL FREE HOSPITAL   (United Kingdom)

ⁱ ST MARY S HOSPITAL   (United Kingdom)

^j ST MICHAEL'S HOSPITAL   (United Kingdom)

^k BELFAST CITY HOSPITAL   (United Kingdom)

^l CARDIFF UNIVERSITY   (United Kingdom)

^m Llandudno LL30 1LB   (United Kingdom)

ⁿ JAMES COOK UNIVERSITY HOSPITAL   (United Kingdom)

^o LONDON SCHOOL OF ECONOMICS   (United Kingdom)

^p Create Health Clinic   (United Kingdom)

^q UNIVERSITY OF SUSSEX   (United Kingdom)

^r HARVARD MEDICAL SCHOOL   (United States)

^s MEDICAL RESEARCH COUNCIL   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER SCREENING; CLINICAL RESEARCH; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; OVARY CANCER; PATIENT ATTITUDE; PATIENT PARTICIPATION; PATIENT SELECTION; POSTMENOPAUSE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TRAVELLER DIARRHEA; TRUST; UNITED KINGDOM; MASS SCREENING; METHODOLOGY; MIDDLE AGED; MORTALITY; MULTICENTER STUDY (TOPIC); OVARY TUMOR; RANDOMIZED CONTROLLED TRIAL (TOPIC); STATISTICS;

AGED; FEMALE; GREAT BRITAIN; HUMANS; MASS SCREENING; MIDDLE AGED; MULTICENTER STUDIES AS TOPIC; OVARIAN NEOPLASMS; PATIENT ACCEPTANCE OF HEALTH CARE; PATIENT SELECTION; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESEARCH DESIGN;

EID: 57549090978     PISSN: 09598146     EISSN: 17561833     Source Type: Journal    
DOI: 10.1136/bmj.a2079     Document Type: Article

References (14)

1. McDonald AM, Knight RC, Campbell MK, Entwistle VA, Grant AM, Cook JA, et al. What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies. Trials 2006;7:9.
2. Jacobs I, Stabile I, Bridges J, Kemsley P, Reynolds C, Grudzinskas J, et al. Multimodal approach to screening for ovarian cancer. Lancet 1988;i:268-71.
3. Jacobs I, Davies AP, Bridges J, Stabile I, Fay T, Lower A, et al. Prevalence screening for ovarian cancer in postmenopausal women by CA 125 measurement and ultrasonography. BMJ 1993;306:1030-4.
4. Jacobs IJ, Skates S, Davies AP, Woolas RP, Jeyerajah A, Weidemann P, et al. Risk of diagnosis of ovarian cancer after raised serum CA 125 concentration: a prospective cohort study. BMJ 1996;313:1355-8.
5. Jacobs IJ, Skates SJ, MacDonald N, Menon U, Rosenthal AN, Davies AP, et al. Screening for ovarian cancer: a pilot randomised controlled trial. Lancet 1999;353:1207-10.
6. Menon U, Skates SJ, Lewis S, Rosenthal AN, Rufford B, Sibley K, et al. Prospective study using the risk of ovarian cancer algorithm to screen for ovarian cancer. J Clin Oncol 2005;23:7919-26.
7. Menon U, Burnell M, Sharma A, Gentry-Maharaj A, Fraser L, Ryan A, et al. Decline in use of hormone therapy among postmenopausal women in the United Kingdom. Menopause 2007;14:462-7.
8. Atkin WS, Hart A, Edwards R, McIntyre P, Aubrey R, Wardle J, et al. Uptake, yield of neoplasia, and adverse effects of flexible sigmoidoscopy screening. Gut 1998;42:560-5.
9. Office for National Statistics. Cancer statistics registrations: registrations of cancer diagnosed in 2004, England. Series MB1 35 2004;24.
10. UK Flexible Sigmoidoscopy Screening Trial Investigators. Single flexible sigmoidoscopy screening to prevent colorectal cancer: baseline findings of a UK multicentre randomised trial. Lancet 2002;359:1291-300.
11. Gray M, Pennington CR. Screening sigmoidoscopy: a randomised trial of invitation style. Health Bull (Edinb) 2000;58:137-40.
12. Paine BJ, Stocks NP, Maclennan AH. Seminars may increase recruitment to randomised controlled trials: lessons learned from WISDOM. Trials 2008;9:5.
13. Cosgrove N, Borhani NO, Bailey G, Borhani P, Levin J, Hoffmeier M, et al. Mass mailing and staff experienced a total recruitment program for a clinical trial: the SHEP experience. Control Clin Trials 1999;20:133-48.
14. Atkin WS, Edwards R, Wardle J, Northover JM, Sutton S, Hart AR, et al. Design of a multicentre randomised trial to evaluate flexible sigmoidoscopy in colorectal cancer screening. J Med Screen 2001;8:137-44.