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Volumn 139, Issue 11, 2013, Pages 1795-1805

Uncovering a key to the process of metastasis in human cancers: A review of critical regulators of anoikis

Author keywords

Anoikis; Apoptosis; Cancer; Mechanism; Metastasis; Regulation

Indexed keywords

BH3 PROTEIN; CASPASE; CASPASE 8; CAVEOLIN 1; CYTOCHROME C; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FAS ANTIGEN; FLICE INHIBITORY PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROCASPASE 8; PROTEIN 14 3 3; PROTEIN 14 3 3 LAMBDA; PROTEIN BCL XL; PROTEIN BIT1; PROTEIN CDCP 1; PROTEIN KINASE B; PROTEIN MCL 1; PROTEIN P53; REGULATOR PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84892679861     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-013-1482-5     Document Type: Review
Times cited : (53)

References (94)
  • 1
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • doi:10. 1038/sj.onc.1210220
    • Adams JM, Cory S (2007) The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26(9):1324-1337. doi:10. 1038/sj.onc.1210220
    • (2007) Oncogene , vol.26 , Issue.9 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 2
    • 73149112184 scopus 로고    scopus 로고
    • Bim-targeted cancer therapy: A link between drug action and underlying molecular changes
    • doi:10.1158/1535-7163.MCT-09-0685
    • Akiyama T, Dass CR, Choong PFM (2009) Bim-targeted cancer therapy: a link between drug action and underlying molecular changes. Mol Cancer Ther 8(12):3173-3180. doi:10.1158/1535-7163.MCT-09-0685
    • (2009) Mol Cancer Ther , vol.8 , Issue.12 , pp. 3173-3180
    • Akiyama, T.1    Dass, C.R.2    Choong, P.F.M.3
  • 3
    • 33745841867 scopus 로고    scopus 로고
    • Urokinase signaling through its receptor protects against anoikis by increasing BCLxL expression levels
    • Alfano D, Iaccarino I, Stoppelli MP (2006) Urokinase signaling through its receptor protects against anoikis by increasing BCLxL expression levels. J Biol Chem 281(26):17758-17767
    • (2006) J Biol Chem , vol.281 , Issue.26 , pp. 17758-17767
    • Alfano, D.1    Iaccarino, I.2    Stoppelli, M.P.3
  • 4
    • 73749083635 scopus 로고    scopus 로고
    • Cellular FLICEinhibitory protein (c-FLIP) signalling: A key regulator of receptor-mediated apoptosis in physiologic context and in cancer
    • doi:10.1016/j. biocel.2009.11.015
    • Bagnoli M, Canevari S, Mezzanzanica D (2010) Cellular FLICEinhibitory protein (c-FLIP) signalling: a key regulator of receptor-mediated apoptosis in physiologic context and in cancer. Int J Biochem Cell Biol 42(2):210-213. doi:10.1016/j. biocel.2009.11.015
    • (2010) Int J Biochem Cell Biol , vol.42 , Issue.2 , pp. 210-213
    • Bagnoli, M.1    Canevari, S.2    Mezzanzanica, D.3
  • 5
    • 77958608445 scopus 로고    scopus 로고
    • AES/GRG5: More than just a dominant-negative TLE/GRG family member
    • doi:10.1002/dvdy.22439
    • Beagle B, Johnson GV (2010) AES/GRG5: more than just a dominant-negative TLE/GRG family member. Dev Dyn 239(11):2795-2805. doi:10.1002/dvdy.22439
    • (2010) Dev Dyn , vol.239 , Issue.11 , pp. 2795-2805
    • Beagle, B.1    Johnson, G.V.2
  • 6
    • 57649130592 scopus 로고    scopus 로고
    • Protein kinase D is a positive regulator of Bit1 apoptotic function
    • doi:10.1074/jbc.M803139200
    • Biliran H, Jan Y, Chen R, Pasquale EB, Ruoslahti E (2008) Protein kinase D is a positive regulator of Bit1 apoptotic function. J Biol Chem 283(42):28029-28037. doi:10.1074/jbc.M803139200
    • (2008) J Biol Chem , vol.283 , Issue.42 , pp. 28029-28037
    • Biliran, H.1    Jan, Y.2    Chen, R.3    Pasquale, E.B.4    Ruoslahti, E.5
  • 7
    • 65549096830 scopus 로고    scopus 로고
    • Mcl-1 is required for melanoma cell resistance to anoikis
    • doi:10.1158/1541-7786.MCR-08-0358
    • Boisvert-Adamo K, Longmate W, Abel EV, Aplin AE (2009) Mcl-1 is required for melanoma cell resistance to anoikis. Mol Cancer Res 7(4):549-556. doi:10.1158/1541-7786.MCR-08-0358
    • (2009) Mol Cancer Res , vol.7 , Issue.4 , pp. 549-556
    • Boisvert-Adamo, K.1    Longmate, W.2    Abel, E.V.3    Aplin, A.E.4
  • 9
    • 84869222355 scopus 로고    scopus 로고
    • TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells
    • doi:10.1158/1541-7786.MCR-12-0144
    • Brunquell C, Biliran H, Jennings S, Ireland SK, Chen R, Ruoslahti E (2012) TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells. Mol Cancer Res 10(11):1482-1495. doi:10.1158/1541-7786.MCR-12-0144
    • (2012) Mol Cancer Res , vol.10 , Issue.11 , pp. 1482-1495
    • Brunquell, C.1    Biliran, H.2    Jennings, S.3    Ireland, S.K.4    Chen, R.5    Ruoslahti, E.6
  • 11
    • 22544464689 scopus 로고    scopus 로고
    • Expression of cellular FLICE/caspase-8 inhibitory protein is associated with malignant potential in endometrial carcinoma
    • Chen HX, Liu YJ, Zhou XD, Luo RY (2005) Expression of cellular FLICE/caspase-8 inhibitory protein is associated with malignant potential in endometrial carcinoma. Int J Gynecol Cancer 15(4):663-670
    • (2005) Int J Gynecol Cancer , vol.15 , Issue.4 , pp. 663-670
    • Chen, H.X.1    Liu, Y.J.2    Zhou, X.D.3    Luo, R.Y.4
  • 12
    • 77955711835 scopus 로고    scopus 로고
    • The antiapoptotic protein, FLIP, is regulated by heterogeneous nuclear ribonucleoprotein K and correlates with poor overall survival of nasopharyngeal carcinoma patients
    • Chen LC, Chung IC, Hsueh C, Tsang NM, Chi LM, Liang Y, Chen CC, Wang LJ, Chang YS (2010) The antiapoptotic protein, FLIP, is regulated by heterogeneous nuclear ribonucleoprotein K and correlates with poor overall survival of nasopharyngeal carcinoma patients. Cell Death Differ 17(9):1463-1473
    • (2010) Cell Death Differ , vol.17 , Issue.9 , pp. 1463-1473
    • Chen, L.C.1    Chung, I.C.2    Hsueh, C.3    Tsang, N.M.4    Chi, L.M.5    Liang, Y.6    Chen, C.C.7    Wang, L.J.8    Chang, Y.S.9
  • 13
    • 78649615697 scopus 로고    scopus 로고
    • Increased levels of hypoxia-inducible factor-1a are associated with Bcl-xL expression, tumor apoptosis, and clinical outcome in chondrosarcoma
    • Chen C, Zhou H, Wei F, Jiang L, Liu X, Liu Z, Ma Q (2011) Increased levels of hypoxia-inducible factor-1a are associated with Bcl-xL expression, tumor apoptosis, and clinical outcome in chondrosarcoma. J Orthop Res 29(1):143-151
    • (2011) J Orthop Res , vol.29 , Issue.1 , pp. 143-151
    • Chen, C.1    Zhou, H.2    Wei, F.3    Jiang, L.4    Liu, X.5    Liu, Z.6    Ma, Q.7
  • 14
    • 84874330789 scopus 로고    scopus 로고
    • Application of a proapoptotic peptide to intratumorally spreading cancer therapy
    • doi:10. 1158/0008-5472.CAN-12-1979
    • Chen R, Braun GB, Luo X, Sugahara KN, Teesalu T, Ruoslahti E (2013) Application of a proapoptotic peptide to intratumorally spreading cancer therapy. Cancer Res 73(4):1352-1361. doi:10. 1158/0008-5472.CAN-12-1979
    • (2013) Cancer Res , vol.73 , Issue.4 , pp. 1352-1361
    • Chen, R.1    Braun, G.B.2    Luo, X.3    Sugahara, K.N.4    Teesalu, T.5    Ruoslahti, E.6
  • 15
    • 55949128465 scopus 로고    scopus 로고
    • Anoikis: A necessary death program for anchorage-dependent cells
    • doi:10.1016/j.bcp.2008.07.023
    • Chiarugi P, Giannoni E (2008) Anoikis: a necessary death program for anchorage-dependent cells. Biochem Pharmacol 76(11):1352-1364. doi:10.1016/j.bcp.2008.07.023
    • (2008) Biochem Pharmacol , vol.76 , Issue.11 , pp. 1352-1364
    • Chiarugi, P.1    Giannoni, E.2
  • 16
    • 84860521179 scopus 로고    scopus 로고
    • Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells
    • doi:10.1152/ajpcell.00318.2011
    • Chunhacha P, Pongrakhananon V, Rojanasakul Y, Chanvorachote P (2012) Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells. Am J Physiol Cell Physiol 302(9):C1284-C1292. doi:10.1152/ajpcell.00318.2011
    • (2012) Am J Physiol Cell Physiol , vol.302 , Issue.9
    • Chunhacha, P.1    Pongrakhananon, V.2    Rojanasakul, Y.3    Chanvorachote, P.4
  • 17
    • 78449281238 scopus 로고    scopus 로고
    • Cancer therapy beyond apoptosis: Autophagy and anoikis as mechanisms of cell death
    • Coates JM, Galante JM, Bold RJ (2010) Cancer therapy beyond apoptosis: autophagy and anoikis as mechanisms of cell death. J Surg Res 164(2):301-308
    • (2010) J Surg Res , vol.164 , Issue.2 , pp. 301-308
    • Coates, J.M.1    Galante, J.M.2    Bold, R.J.3
  • 18
    • 0037171468 scopus 로고    scopus 로고
    • Increased Bcl-xL expression mediates v-Src-induced resistance to anoikis in intestinal epithelial cells
    • Coll ML, Rosen K, Ladeda V, Filmus J (2002) Increased Bcl-xL expression mediates v-Src-induced resistance to anoikis in intestinal epithelial cells. Oncogene 21(18):2908-2913
    • (2002) Oncogene , vol.21 , Issue.18 , pp. 2908-2913
    • Coll, M.L.1    Rosen, K.2    Ladeda, V.3    Filmus, J.4
  • 19
    • 84861766071 scopus 로고    scopus 로고
    • BCL-2 family proteins: The mitochondrial apoptotic key regulators
    • Daisy P, Saipriya K (2012) BCL-2 family proteins: the mitochondrial apoptotic key regulators. Curr Cancer Ther Rev 8(2):133-140
    • (2012) Curr Cancer Ther Rev , vol.8 , Issue.2 , pp. 133-140
    • Daisy, P.1    Saipriya, K.2
  • 20
    • 40949148735 scopus 로고    scopus 로고
    • 14-3-3 zeta down-regulates p53 in mammary epithelial cells and confers luminal filling
    • doi:10. 1158/0008-5472.CAN-07-3177
    • Danes CG, Wyszomierski SL, Lu J, Neal CL, Yang W, Yu D (2008) 14-3-3 zeta down-regulates p53 in mammary epithelial cells and confers luminal filling. Cancer Res 68(6):1760-1767. doi:10. 1158/0008-5472.CAN-07-3177
    • (2008) Cancer Res , vol.68 , Issue.6 , pp. 1760-1767
    • Danes, C.G.1    Wyszomierski, S.L.2    Lu, J.3    Neal, C.L.4    Yang, W.5    Yu, D.6
  • 21
    • 37549069901 scopus 로고    scopus 로고
    • BCL-2 family proteins: Critical checkpoints of apoptotic cell death
    • doi:10. 1158/1078-0432.CCR-07-1598
    • Danial NN (2007) BCL-2 family proteins: critical checkpoints of apoptotic cell death. Clin Cancer Res 13(24):7254-7263. doi:10. 1158/1078-0432.CCR-07- 1598
    • (2007) Clin Cancer Res , vol.13 , Issue.24 , pp. 7254-7263
    • Danial, N.N.1
  • 22
    • 27544471076 scopus 로고    scopus 로고
    • The mitochondrial death squad: Hardened killers or innocent bystanders?
    • doi:10.1016/j.ceb.2005.09.001
    • Ekert PG, Vaux DL (2005) The mitochondrial death squad: hardened killers or innocent bystanders? Curr Opin Cell Biol 17(6):626-630. doi:10.1016/j.ceb. 2005.09.001
    • (2005) Curr Opin Cell Biol , vol.17 , Issue.6 , pp. 626-630
    • Ekert, P.G.1    Vaux, D.L.2
  • 23
    • 84874896655 scopus 로고    scopus 로고
    • The cellular decision between apoptosis and autophagy
    • Fan YJ, Zong WX (2013) The cellular decision between apoptosis and autophagy. Chin J Cancer 32(3):121-129
    • (2013) Chin J Cancer , vol.32 , Issue.3 , pp. 121-129
    • Fan, Y.J.1    Zong, W.X.2
  • 25
    • 40049093105 scopus 로고    scopus 로고
    • Inhibition of signal transducer and activator of transcription 3 expression by RNA interference suppresses invasion through inducing anoikis in human colon cancer cells
    • Fan Y, Zhang YL, Wu Y, Zhang W, Wang YH, Cheng ZM, Li H (2008) Inhibition of signal transducer and activator of transcription 3 expression by RNA interference suppresses invasion through inducing anoikis in human colon cancer cells. World J Gastroenterol 14(3):428-434
    • (2008) World J Gastroenterol , vol.14 , Issue.3 , pp. 428-434
    • Fan, Y.1    Zhang, Y.L.2    Wu, Y.3    Zhang, W.4    Wang, Y.H.5    Cheng, Z.M.6    Li, H.7
  • 27
    • 0035874992 scopus 로고    scopus 로고
    • Induction of anoikis and suppression of human ovarian tumor growth in vivo by down-regulation of Bcl-X(L)
    • Frankel A, Rosen K, Filmus J, Kerbel RS (2001) Induction of anoikis and suppression of human ovarian tumor growth in vivo by down-regulation of Bcl-X(L). Cancer Res 61(12):4837-4841
    • (2001) Cancer Res , vol.61 , Issue.12 , pp. 4837-4841
    • Frankel, A.1    Rosen, K.2    Filmus, J.3    Kerbel, R.S.4
  • 28
    • 1542353401 scopus 로고    scopus 로고
    • Control of apoptosis by p53
    • Fridman JS, Lowe SW (2003) Control of apoptosis by p53. Oncogene 22(56 REV. ISS. 8):9030-9040
    • (2003) Oncogene , vol.22 , Issue.56 REV. ISSUE. 8 , pp. 9030-9040
    • Fridman, J.S.1    Lowe, S.W.2
  • 29
    • 0035480032 scopus 로고    scopus 로고
    • Anoikis mechanisms
    • doi:10.1016/S0955-0674(00)00251-9
    • Frisch SM, Screaton RA (2001) Anoikis mechanisms. Curr Opin Cell Biol 13(5):555-562. doi:10.1016/S0955-0674(00)00251-9
    • (2001) Curr Opin Cell Biol , vol.13 , Issue.5 , pp. 555-562
    • Frisch, S.M.1    Screaton, R.A.2
  • 31
    • 24744435397 scopus 로고    scopus 로고
    • Mammalian Groucho homologs: Redundancy or specificity?
    • doi:10.1002/jcb.20476
    • Gasperowicz M, Otto F (2005) Mammalian Groucho homologs: redundancy or specificity? J Cell Biochem 95(4):670-687. doi:10.1002/jcb.20476
    • (2005) J Cell Biochem , vol.95 , Issue.4 , pp. 670-687
    • Gasperowicz, M.1    Otto, F.2
  • 33
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC (1998) Mitochondria and apoptosis. Science 281(5381):1309-1312
    • (1998) Science , vol.281 , Issue.5381 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 34
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144(5):646-674
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 35
    • 33744544172 scopus 로고    scopus 로고
    • 14-3-3 proteins in cell cycle regulation
    • doi:10.1016/j. semcancer.2006.03.002
    • Hermeking H, Benzinger A (2006) 14-3-3 proteins in cell cycle regulation. Semin Cancer Biol 16(3):183-192. doi:10.1016/j. semcancer.2006.03.002
    • (2006) Semin Cancer Biol , vol.16 , Issue.3 , pp. 183-192
    • Hermeking, H.1    Benzinger, A.2
  • 36
    • 1542328956 scopus 로고    scopus 로고
    • A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors
    • doi:10.1016/S0092-8674(04)00204-1
    • Jan Y, Matter M, Pai JT, Chen YL, Pilch J, Komatsu M, Ong E, Fukuda M, Ruoslahti E (2004) A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors. Cell 116(5):751-762. doi:10.1016/S0092-8674(04)00204-1
    • (2004) Cell , vol.116 , Issue.5 , pp. 751-762
    • Jan, Y.1    Matter, M.2    Pai, J.T.3    Chen, Y.L.4    Pilch, J.5    Komatsu, M.6    Ong, E.7    Fukuda, M.8    Ruoslahti, E.9
  • 38
    • 80054915955 scopus 로고    scopus 로고
    • Inhibition of gap junction transfer sensitizes thyroid cancer cells to anoikis
    • Jensen K, Patel A, Klubo-Gwiezdzinska J, Bauer A, Vasko V (2011) Inhibition of gap junction transfer sensitizes thyroid cancer cells to anoikis. Endocr Relat Cancer 18(5):613-626
    • (2011) Endocr Relat Cancer , vol.18 , Issue.5 , pp. 613-626
    • Jensen, K.1    Patel, A.2    Klubo-Gwiezdzinska, J.3    Bauer, A.4    Vasko, V.5
  • 39
    • 25144489068 scopus 로고    scopus 로고
    • Overview of cell death signaling pathways
    • Jin Z, El-Deiry WS (2005) Overview of cell death signaling pathways. Cancer Biol Ther 4(2):139-163
    • (2005) Cancer Biol Ther , vol.4 , Issue.2 , pp. 139-163
    • Jin, Z.1    El-Deiry, W.S.2
  • 42
    • 38749105026 scopus 로고    scopus 로고
    • Hepatocyte growth factor induces anoikis resistance by up-regulation of cyclooxygenase-2 expression in uterine endometrial cancer cells
    • Kanayama S, Yamada Y, Kawaguchi R, Tsuji Y, Haruta S, Kobayashi H (2008) Hepatocyte growth factor induces anoikis resistance by up-regulation of cyclooxygenase-2 expression in uterine endometrial cancer cells. Oncol Rep 19(1):117-122
    • (2008) Oncol Rep , vol.19 , Issue.1 , pp. 117-122
    • Kanayama, S.1    Yamada, Y.2    Kawaguchi, R.3    Tsuji, Y.4    Haruta, S.5    Kobayashi, H.6
  • 43
    • 80051997985 scopus 로고    scopus 로고
    • Metastasis of tumor cells is enhanced by downregulation of Bit1
    • doi:10.1371/journal.pone. 0023840
    • Karmali PP, Brunquell C, Tram H, Ireland SK, Ruoslahti E, Biliran H (2011) Metastasis of tumor cells is enhanced by downregulation of Bit1. PLoS One 6(8):e23840. doi:10.1371/journal.pone. 0023840
    • (2011) PLoS One , vol.6 , Issue.8
    • Karmali, P.P.1    Brunquell, C.2    Tram, H.3    Ireland, S.K.4    Ruoslahti, E.5    Biliran, H.6
  • 44
    • 84863357474 scopus 로고    scopus 로고
    • Anoikis resistance: An essential prerequisite for tumor metastasis
    • Article ID 306879. doi:10.1155/2012/306879
    • Kim YN, Koo KH, Sung JY, Yun UJ, Kim H (2012) Anoikis resistance: an essential prerequisite for tumor metastasis. Int J Cell Biol 2012. Article ID 306879. doi:10.1155/2012/306879
    • (2012) Int J Cell Biol 2012
    • Kim, Y.N.1    Koo, K.H.2    Sung, J.Y.3    Yun, U.J.4    Kim, H.5
  • 45
  • 46
    • 84861716941 scopus 로고    scopus 로고
    • Pokemon silencing leads to bim-mediated anoikis of human hepatoma cell QGY7703
    • doi:10.3390/ ijms13055818
    • Liu K, Liu F, Zhang N, Liu S, Jiang Y (2012) Pokemon silencing leads to bim-mediated anoikis of human hepatoma cell QGY7703. Int J Mol Sci 13(5):5818-5831. doi:10.3390/ ijms13055818
    • (2012) Int J Mol Sci , vol.13 , Issue.5 , pp. 5818-5831
    • Liu, K.1    Liu, F.2    Zhang, N.3    Liu, S.4    Jiang, Y.5
  • 47
    • 57149135309 scopus 로고    scopus 로고
    • Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by bax
    • doi:10.1016/j.cell.2008. 11.010
    • Lovell JF, Billen LP, Bindner S, Shamas-Din A, Fradin C, Leber B, Andrews DW (2008) Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by bax. Cell 135(6):1074-1084. doi:10.1016/j.cell.2008. 11.010
    • (2008) Cell , vol.135 , Issue.6 , pp. 1074-1084
    • Lovell, J.F.1    Billen, L.P.2    Bindner, S.3    Shamas-Din, A.4    Fradin, C.5    Leber, B.6    Andrews, D.W.7
  • 48
    • 84860232887 scopus 로고    scopus 로고
    • 14-3-3 zeta as novel molecular target for cancer therapy
    • Matta A, Michael Siu KW, Ralhan R (2012) 14-3-3 zeta as novel molecular target for cancer therapy. Expert Opin Ther Targets 16(5):515-523
    • (2012) Expert Opin Ther Targets , vol.16 , Issue.5 , pp. 515-523
    • Matta, A.1    Michael Siu, K.W.2    Ralhan, R.3
  • 51
    • 78249285952 scopus 로고    scopus 로고
    • 14-3-3f as a prognostic marker and therapeutic target for cancer
    • doi:10.1517/14728222.2010.531011
    • Neal CL, Yu D (2010) 14-3-3f as a prognostic marker and therapeutic target for cancer. Expert Opin Ther Targets 14(12):1343-1354. doi:10.1517/14728222.2010.531011
    • (2010) Expert Opin Ther Targets , vol.14 , Issue.12 , pp. 1343-1354
    • Neal, C.L.1    Yu, D.2
  • 53
    • 33748967069 scopus 로고    scopus 로고
    • Of extracellular matrix, scaffolds, and signaling: Tissue architecture regulates development, homeostasis, and cancer
    • Nelson CM, Bissell MJ (2006) Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer. Annu Rev Cell Dev Biol 22:287-309
    • (2006) Annu Rev Cell Dev Biol , vol.22 , pp. 287-309
    • Nelson, C.M.1    Bissell, M.J.2
  • 55
    • 80455154960 scopus 로고    scopus 로고
    • Structural basis of 14-3-3 protein functions
    • doi:10.1016/j. semcdb.2011.09.001
    • Obsil T, Obsilova V (2011) Structural basis of 14-3-3 protein functions. Semin Cell Dev Biol 22(7):663-672. doi:10.1016/j. semcdb.2011.09.001
    • (2011) Semin Cell Dev Biol , vol.22 , Issue.7 , pp. 663-672
    • Obsil, T.1    Obsilova, V.2
  • 56
    • 67650741483 scopus 로고    scopus 로고
    • Mitochondrial targeting of tBid/Bax: A role for the TOM complex?
    • Ott M, Norberg E, Zhivotovsky B, Orrenius S (2009) Mitochondrial targeting of tBid/Bax: a role for the TOM complex? Cell Death Differ 16(8):1075-1082
    • (2009) Cell Death Differ , vol.16 , Issue.8 , pp. 1075-1082
    • Ott, M.1    Norberg, E.2    Zhivotovsky, B.3    Orrenius, S.4
  • 58
    • 84873723103 scopus 로고    scopus 로고
    • Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts
    • Rao-Bindal K, Rao CK, Yu L, Kleinerman ES (2013) Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts. Pediatr Blood Cancer 60(4):575-579
    • (2013) Pediatr Blood Cancer , vol.60 , Issue.4 , pp. 575-579
    • Rao-Bindal, K.1    Rao, C.K.2    Yu, L.3    Kleinerman, E.S.4
  • 59
    • 33748072402 scopus 로고    scopus 로고
    • Caveolin-1 inhibits anoikis and promotes survival signaling in cancer cells
    • Ravid D, Maor S, Werner H, Liscovitch M (2006) Caveolin-1 inhibits anoikis and promotes survival signaling in cancer cells. Adv Enzyme Regul 46:163-175
    • (2006) Adv Enzyme Regul , vol.46 , pp. 163-175
    • Ravid, D.1    Maor, S.2    Werner, H.3    Liscovitch, M.4
  • 60
    • 0037115740 scopus 로고    scopus 로고
    • Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein
    • doi:10.1042/BJ20020972
    • Roucou X, Montessuit S, Antonsson B, Martinou JC (2002) Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein. Biochem J 368(3):915-921. doi:10.1042/BJ20020972
    • (2002) Biochem J , vol.368 , Issue.3 , pp. 915-921
    • Roucou, X.1    Montessuit, S.2    Antonsson, B.3    Martinou, J.C.4
  • 61
    • 79959736864 scopus 로고    scopus 로고
    • Targeting the anti-apoptotic protein c-FLIP for cancer therapy
    • doi:10. 3390/cancers3021639
    • Safa AR, Pollok KE (2011) Targeting the anti-apoptotic protein c-FLIP for cancer therapy. Cancers 3(2):1639-1671. doi:10. 3390/cancers3021639
    • (2011) Cancers , vol.3 , Issue.2 , pp. 1639-1671
    • Safa, A.R.1    Pollok, K.E.2
  • 63
    • 77951480423 scopus 로고    scopus 로고
    • Targeting anoikis resistance in prostate cancer metastasis
    • Sakamoto S, Kyprianou N (2010) Targeting anoikis resistance in prostate cancer metastasis. Mol Aspects Med 31(2):205-214
    • (2010) Mol Aspects Med , vol.31 , Issue.2 , pp. 205-214
    • Sakamoto, S.1    Kyprianou, N.2
  • 64
    • 79551599947 scopus 로고    scopus 로고
    • ABT-263, a Bcl-2 inhibitor, enhances the susceptibility of lung adenocarcinoma cells treated with Src inhibitors to anoikis
    • doi:10. 3892/or.2010.1123
    • Sakuma Y, Tsunezumi J, Nakamura Y, Yoshihara M, Matsukuma S, Koizume S, Miyagi Y (2011) ABT-263, a Bcl-2 inhibitor, enhances the susceptibility of lung adenocarcinoma cells treated with Src inhibitors to anoikis. Oncol Rep 25(3):661-667. doi:10. 3892/or.2010.1123
    • (2011) Oncol Rep , vol.25 , Issue.3 , pp. 661-667
    • Sakuma, Y.1    Tsunezumi, J.2    Nakamura, Y.3    Yoshihara, M.4    Matsukuma, S.5    Koizume, S.6    Miyagi, Y.7
  • 65
    • 79960913158 scopus 로고    scopus 로고
    • Targeting the extrinsic apoptosis signaling pathway for cancer therapy
    • Sayers TJ (2011) Targeting the extrinsic apoptosis signaling pathway for cancer therapy. Cancer Immunol Immunother 60(8):1173-1180
    • (2011) Cancer Immunol Immunother , vol.60 , Issue.8 , pp. 1173-1180
    • Sayers, T.J.1
  • 66
    • 79955917652 scopus 로고    scopus 로고
    • The role of TLE1 in synovial sarcoma
    • doi:10.1002/jor.21318
    • Seo SW, Lee H, Lee HI, Kim HS (2011) The role of TLE1 in synovial sarcoma. J Orthop Res 29(7):1131-1136. doi:10.1002/jor.21318
    • (2011) J Orthop Res , vol.29 , Issue.7 , pp. 1131-1136
    • Seo, S.W.1    Lee, H.2    Lee, H.I.3    Kim, H.S.4
  • 68
    • 0037227946 scopus 로고    scopus 로고
    • Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis
    • doi:10.1038/ncb894
    • Shirane M, Nakayama KI (2003) Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis. Nat Cell Biol 5(1):28-37. doi:10.1038/ncb894
    • (2003) Nat Cell Biol , vol.5 , Issue.1 , pp. 28-37
    • Shirane, M.1    Nakayama, K.I.2
  • 69
    • 55949136859 scopus 로고    scopus 로고
    • Anoikis resistance and tumor metastasis
    • doi:10.1016/ j.canlet.2008.05.029
    • Simpson CD, Anyiwe K, Schimmer AD (2008) Anoikis resistance and tumor metastasis. Cancer Lett 272(2):177-185. doi:10.1016/ j.canlet.2008.05.029
    • (2008) Cancer Lett , vol.272 , Issue.2 , pp. 177-185
    • Simpson, C.D.1    Anyiwe, K.2    Schimmer, A.D.3
  • 71
    • 2342552085 scopus 로고    scopus 로고
    • A Bit-role for integrins in apoptosis
    • doi:10.1038/ncb0504-388
    • Stupack DG, Cheresh DA (2004) A Bit-role for integrins in apoptosis. Nat Cell Biol 6(5):388-389. doi:10.1038/ncb0504-388
    • (2004) Nat Cell Biol , vol.6 , Issue.5 , pp. 388-389
    • Stupack, D.G.1    Cheresh, D.A.2
  • 72
    • 82755190844 scopus 로고    scopus 로고
    • Anoikis: An emerging hallmark in health and diseases
    • doi:10.1002/path.3000
    • Taddei ML, Giannoni E, Fiaschi T, Chiarugi P (2012) Anoikis: an emerging hallmark in health and diseases. J Pathol 226(2):380-393. doi:10.1002/path.3000
    • (2012) J Pathol , vol.226 , Issue.2 , pp. 380-393
    • Taddei, M.L.1    Giannoni, E.2    Fiaschi, T.3    Chiarugi, P.4
  • 73
    • 84862528688 scopus 로고    scopus 로고
    • Emerging roles of angiopoietin-like 4 in human cancer
    • doi:10.1158/1541-7786.MCR-11-0519
    • Tan MJ, Teo Z, Sng MK, Zhu P, Tan NS (2012) Emerging roles of angiopoietin-like 4 in human cancer. Mol Cancer Res 10(6):677-688. doi:10.1158/1541-7786.MCR-11-0519
    • (2012) Mol Cancer Res , vol.10 , Issue.6 , pp. 677-688
    • Tan, M.J.1    Teo, Z.2    Sng, M.K.3    Zhu, P.4    Tan, N.S.5
  • 74
    • 76749107447 scopus 로고    scopus 로고
    • C-Met overexpression contributes to the acquired apoptotic resistance of nonadherent ovarian cancer cells through a cross talk mediated by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase 1/2
    • Tang MKS, Zhou HY, Yam JWP, Wong AST (2010) c-Met overexpression contributes to the acquired apoptotic resistance of nonadherent ovarian cancer cells through a cross talk mediated by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase 1/2. Neoplasia 12(2):128-138
    • (2010) Neoplasia , vol.12 , Issue.2 , pp. 128-138
    • Tang, M.K.S.1    Zhou, H.Y.2    Yam, J.W.P.3    Wong, A.S.T.4
  • 76
    • 80054982459 scopus 로고    scopus 로고
    • Roles of CUB domain-containing protein 1 signaling in cancer invasion and metastasis
    • doi:10.1111/j.1349-7006.2011.02052.x
    • Uekita T, Sakai R (2011) Roles of CUB domain-containing protein 1 signaling in cancer invasion and metastasis. Cancer Sci 102(11):1943-1948. doi:10.1111/j.1349-7006.2011.02052.x
    • (2011) Cancer Sci , vol.102 , Issue.11 , pp. 1943-1948
    • Uekita, T.1    Sakai, R.2
  • 77
    • 35649025769 scopus 로고    scopus 로고
    • CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma
    • Uekita T, Jia L, Narisawa-Saito M, Yokota J, Kiyono T, Sakai R (2007) CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma. Mol Cell Biol 27(21):7649-7660
    • (2007) Mol Cell Biol , vol.27 , Issue.21 , pp. 7649-7660
    • Uekita, T.1    Jia, L.2    Narisawa-Saito, M.3    Yokota, J.4    Kiyono, T.5    Sakai, R.6
  • 79
    • 80051668693 scopus 로고    scopus 로고
    • Apoptosis: Why and how does it occur in biology?
    • Ulukaya E, Acilan C, Yilmaz Y (2011) Apoptosis: why and how does it occur in biology? Cell Biochem Funct 29(6):468-480
    • (2011) Cell Biochem Funct , vol.29 , Issue.6 , pp. 468-480
    • Ulukaya, E.1    Acilan, C.2    Yilmaz, Y.3
  • 81
    • 32144462302 scopus 로고    scopus 로고
    • Interactions of Bax and tBid with lipid monolayers
    • doi:10.1007/s00232-005-0799-7
    • Van Mau N, Kajava AV, Bonfils C, Martinou JC, Harricane MC (2005) Interactions of Bax and tBid with lipid monolayers. J Membr Biol 207(1):1-9. doi:10.1007/s00232-005-0799-7
    • (2005) J Membr Biol , vol.207 , Issue.1 , pp. 1-9
    • Van Mau, N.1    Kajava, A.V.2    Bonfils, C.3    Martinou, J.C.4    Harricane, M.C.5
  • 82
    • 70349246434 scopus 로고    scopus 로고
    • Prognostic role of myeloid cell leukemia-1 protein (Mcl-1) expression in human gastric cancer
    • Wang L, Liu Q, Zhou W, Shao H, Li F, Li X (2009) Prognostic role of myeloid cell leukemia-1 protein (Mcl-1) expression in human gastric cancer. J Surg Oncol 100(5):396-400
    • (2009) J Surg Oncol , vol.100 , Issue.5 , pp. 396-400
    • Wang, L.1    Liu, Q.2    Zhou, W.3    Shao, H.4    Li, F.5    Li, X.6
  • 83
    • 77955983894 scopus 로고    scopus 로고
    • Functional and biological analysis of Bcl-xL expression in human osteosarcoma
    • Wang ZX, Yang JS, Pan X, Wang JR, Li J, Yin YM, De W (2010) Functional and biological analysis of Bcl-xL expression in human osteosarcoma. Bone 47(2):445-454
    • (2010) Bone , vol.47 , Issue.2 , pp. 445-454
    • Wang, Z.X.1    Yang, J.S.2    Pan, X.3    Wang, J.R.4    Li, J.5    Yin, Y.M.6    De, W.7
  • 85
    • 48849090371 scopus 로고    scopus 로고
    • Bcl-2 family proteins: The sentinels of the mitochondrial apoptosis pathway
    • doi:10.1002/iub.51
    • Wong WWL, Puthalakath H (2008) Bcl-2 family proteins: the sentinels of the mitochondrial apoptosis pathway. IUBMB Life 60(6):390-397. doi:10.1002/iub.51
    • (2008) IUBMB Life , vol.60 , Issue.6 , pp. 390-397
    • Wong, W.W.L.1    Puthalakath, H.2
  • 86
    • 36349017908 scopus 로고    scopus 로고
    • Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis
    • Woods NT, Yamaguchi H, Lee FY, Bhalla KN, Wang HG (2007) Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis. Cancer Res 67(22):10744-10752
    • (2007) Cancer Res , vol.67 , Issue.22 , pp. 10744-10752
    • Woods, N.T.1    Yamaguchi, H.2    Lee, F.Y.3    Bhalla, K.N.4    Wang, H.G.5
  • 87
    • 59149100185 scopus 로고    scopus 로고
    • IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression
    • doi:10.1158/0008-5472.can-08-2520
    • Yang D, Wang S, Brooks C, Dong Z, Schoenlein PV, Kumar V, Ouyang X, Xiong H, Lahat G, Hayes-Jordan A, Lazar A, Pollock R, Lev D, Liu K (2009) IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression. Cancer Res 69(3):1080-1088. doi:10.1158/0008-5472.can-08-2520
    • (2009) Cancer Res , vol.69 , Issue.3 , pp. 1080-1088
    • Yang, D.1    Wang, S.2    Brooks, C.3    Dong, Z.4    Schoenlein, P.V.5    Kumar, V.6    Ouyang, X.7    Xiong, H.8    Lahat, G.9    Hayes-Jordan, A.10    Lazar, A.11    Pollock, R.12    Lev, D.13    Liu, K.14
  • 88
    • 79952897746 scopus 로고    scopus 로고
    • 14-3-3Zeta positive expression is associated with a poor prognosis in patients with glioblastoma
    • Yang X, Cao W, Zhou J, Zhang W, Zhang X, Lin W, Fei Z, Lin H, Wang B (2011) 14-3-3Zeta positive expression is associated with a poor prognosis in patients with glioblastoma. Neurosurgery 68(4):932-938
    • (2011) Neurosurgery , vol.68 , Issue.4 , pp. 932-938
    • Yang, X.1    Cao, W.2    Zhou, J.3    Zhang, W.4    Zhang, X.5    Lin, W.6    Fei, Z.7    Lin, H.8    Wang, B.9
  • 89
    • 38949109297 scopus 로고    scopus 로고
    • Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer
    • Yu X, Liu L, Cai B, He Y, Wan X (2008) Suppression of anoikis by the neurotrophic receptor TrkB in human ovarian cancer. Cancer Sci 29(3):543-552
    • (2008) Cancer Sci , vol.29 , Issue.3 , pp. 543-552
    • Yu, X.1    Liu, L.2    Cai, B.3    He, Y.4    Wan, X.5
  • 90
    • 0037067672 scopus 로고    scopus 로고
    • Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFjB
    • doi:10.1074/jbc.M201598200
    • Zeng Q, Chen S, You Z, Yang F, Carey TE, Saims D, Wang CY (2002) Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFjB. J Biol Chem 277(28):25203-25208. doi:10.1074/jbc.M201598200
    • (2002) J Biol Chem , vol.277 , Issue.28 , pp. 25203-25208
    • Zeng, Q.1    Chen, S.2    You, Z.3    Yang, F.4    Carey, T.E.5    Saims, D.6    Wang, C.Y.7
  • 91
    • 3042823411 scopus 로고    scopus 로고
    • Signalling mechanisms of anoikis
    • Zhan M, Zhao H, Han ZC (2004) Signalling mechanisms of anoikis. Histol Histopathol 19(3):973-983
    • (2004) Histol Histopathol , vol.19 , Issue.3 , pp. 973-983
    • Zhan, M.1    Zhao, H.2    Han, Z.C.3
  • 93
    • 84872822854 scopus 로고    scopus 로고
    • The expression of Mcl-1 in human cervical cancer and its clinical significance
    • Zhang T, Zhao C, Luo L, Zhao H, Cheng J, Xu F (2012) The expression of Mcl-1 in human cervical cancer and its clinical significance. Med Oncol 29(3):1985-1991
    • (2012) Med Oncol , vol.29 , Issue.3 , pp. 1985-1991
    • Zhang, T.1    Zhao, C.2    Luo, L.3    Zhao, H.4    Cheng, J.5    Xu, F.6


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