Tat-DJ-1 protects neurons from ischemic damage in the ventral horn of rabbit spinal cord via increasing antioxidant levels

Neurochemical Research

Volumn 39, Issue 1, 2014, Pages 187-193

  Kim, Woosuk ^a   Kim, Dae Won ^e   Jeong, Hoon Jae ^b   Yoo, Dae Young ^a   Jung, Hyo Young ^a   Nam, Sung Min ^a   Kim, Jong Hwi ^a   Choi, Jung Hoon ^c   Won, Moo Ho ^d   Yoon, Yeo Sung ^a   Moon, Seung Myung ^b   Choi, Soo Young ^b   Hwang, In Koo ^a  

^a Seoul National University   (South Korea)

^b Hallym University   (South Korea)

^c Kangwon National University   (South Korea)

^d Kangwon National University   (South Korea)

^e Gangneung Wonju National University   (South Korea)

Author keywords

Catalase; DJ 1; Lipid peroxidation; Neuroprotection; Superoxide dismutase; Transient spinal ischemia

Indexed keywords

ANTIOXIDANT; CATALASE; DJ 1 PROTEIN; HYBRID PROTEIN; MALONALDEHYDE; SUPEROXIDE DISMUTASE; TAT DJ 1 PROTEIN; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA OCCLUSION; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; LIPID PEROXIDATION; MALE; MOTONEURON; MOTOR PERFORMANCE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RABBIT; REPERFUSION INJURY; SPINAL CORD ISCHEMIA; SPINAL CORD VENTRAL HORN;

ORYCTOLAGUS CUNICULUS;

ANIMALS; ANTIOXIDANTS; CATALASE; HINDLIMB; LIPID PEROXIDATION; MALE; ONCOGENE PROTEINS; RABBITS; RECOMBINANT FUSION PROTEINS; REPERFUSION INJURY; SPINAL CORD; SPINAL CORD ISCHEMIA; SUPEROXIDE DISMUTASE;

EID: 84892678186     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-013-1205-y     Document Type: Article

References (40)

1. Cambria RP, Clouse WD, Davison JK, Dunn PF, Corey M, Dorer D (2002) Thoracoabdominal aneurysm repair: results with 337 operations performed over a 15-year interval. Ann Surg 236:471-479
2. Coselli JS, LeMaire SA, Miller CC 3rd et al (2000) Mortality and paraplegia after thoracoabdominal aortic aneurysm repair: a risk factor analysis. Ann Thorac Surg 69:409-414 (Pubitemid 30125568)
3. Bicknell CD, Riga CV, Wolfe JH (2009) Prevention of paraplegia during thoracoabdominal aortic aneurysm repair. Eur J Vasc Endovasc Surg 37:654-660
4. Dröge W (2002) Free radicals in the physiological control of cell function. Physiol Rev 82:47-95 (Pubitemid 34654215)
5. Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J (2007) Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39:44-84 (Pubitemid 44566469)
6. Zecca L, Youdim MB, Riederer P, Connor JR, Crichton RR (2004) Iron, brain ageing and neurodegenerative disorders. Nat Rev Neurosci 5:863-873 (Pubitemid 39482155)
7. Nagakubo D, Taira T, Kitaura H et al (1997) DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem Biophys Res Commun 231:509-513 (Pubitemid 27214343)
8. Bonifati V, Rizzu P, van Baren MJ et al (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299:256-259 (Pubitemid 36131051)
9. Bai Q, Mullett SJ, Garver JA, Hinkle DA, Burton EA (2006) Zebrafish DJ-1 is evolutionarily conserved and expressed in dopaminergic neurons. Brain Res 1113:33-44 (Pubitemid 44396950)
10. Kinumi T, Kimata J, Taira T, Ariga H, Niki E (2004) Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells. Biochem Biophys Res Commun 317:722-728 (Pubitemid 38481432)
11. Yanagisawa D, Kitamura Y, Inden M et al (2008) DJ-1 protects against neurodegeneration caused by focal cerebral ischemia and reperfusion in rats. J Cereb Blood Flow Metab 28:563-578 (Pubitemid 351304267)
12. Yanagida T, Tsushima J, Kitamura Y et al (2009) Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury. Oxid Med Cell Longev 2:36-42
13. Jeong HJ, Kim DW, Kim MJ et al (2012) Protective effects of transduced Tat-DJ-1 protein against oxidative stress and ischemic brain injury. Exp Mol Med 44:586-593
14. Aleyasin H, Rousseaux MW, Phillips M et al (2007) The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage. Proc Natl Acad Sci USA 104:18748-18753 (Pubitemid 350210768)
15. Sakurai M, Kawamura T, Nishimura H, Suzuki H, Tezuka F, Abe K (2009) Induction of Parkinson disease-related proteins in motor neurons after transient spinal cord ischemia in rabbits. J Cereb Blood Flow Metab 29:752-758
16. Kwon HY, Eum WS, Jang HW et al (2000) Transduction of Cu, Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic domain into mammalian cells. FEBS Lett 485:163-167
17. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
18. Kiyoshima T, Fukuda S, Matsumoto M et al (2003) Lack of evidence for apoptosis as a cause of delayed onset paraplegia after spinal cord ischemia in rabbits. Anesth Analg 96:839-846 (Pubitemid 36245578)
19. Tarlov IM (1957) Spinal cord compression: Mechanisms of paralysis and treatment. Charles C Thomas, Springfield
20. Jacobs TP, Kempski O, McKinley D, Dutka AJ, Hallenbeck JM, Feuerstein G (1992) Blood flow and vascular permeability during motor dysfunction in a rabbit model of spinal cord ischemia. Stroke 23:367-373
21. Huang Y, Xie K, Li J et al (2011) Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits. Brain Res 1378:125-136
22. Moore WM Jr, Hollier LH (1991) The influence of severity of spinal cord ischemia in the etiology of delayed-onset paraplegia. Ann Surg 213:427-431
23. Wisselink W, Patetsios P, Panetta TF et al (1998) Medium molecular weight pentastarch reduces reperfusion injury by decreasing capillary leak in an animal model of spinal cord ischemia. J Vasc Surg 27:109-116 (Pubitemid 28081166)
24. Hwang IK, Eum WS, Yoo KY et al (2005) Copper chaperone for Cu, Zn-SOD supplement potentiates the Cu, Zn-SOD function of neuroprotective effects against ischemic neuronal damage in the gerbil hippocampus. Free Radic Biol Med 39:392-402 (Pubitemid 40910196)
25. Chan PH (1996) Role of oxidants in ischemic brain damage. Stroke 27:1124-1129 (Pubitemid 26177617)
26. Liu PK (2003) Ischemia-reperfusion-related repair deficit after oxidative stress: implications of faulty transcripts in neuronal sensitivity after brain injury. J Biomed Sci 10:4-13 (Pubitemid 36173320)
27. Inden M, Taira T, Kitamura Y et al (2006) PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model. Neurobiol Dis 24:144-158 (Pubitemid 44416214)
28. Kim RH, Smith PD, Aleyasin H et al (2005) Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proc Natl Acad Sci USA 102:5215-5220
29. Morimoto N, Nagai M, Miyazaki K et al (2010) Induction of parkinsonism-related proteins in the spinal motor neurons of transgenic mouse carrying a mutant SOD1 gene. J Neurosci Res 88:1804-1811
30. Kim W, Kim DW, Yoo DY et al (2012) Neuroprotective effects of PEP-1-Cu, Zn-SOD against ischemic neuronal damage in the rabbit spinal cord. Neurochem Res 37:307-313
31. Takahashi-Niki K, Niki T, Taira T, Iguchi-Ariga SM, Ariga H (2004) Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients. Biochem Biophys Res Commun 320:389-397 (Pubitemid 38798879)
32. Zhou W, Freed CR (2005) DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity. J Biol Chem 280:43150-43158 (Pubitemid 43049281)
33. Yokota T, Sugawara K, Ito K, Takahashi R, Ariga H, Mizusawa H (2003) Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition. Biochem Biophys Res Commun 312:1342-1348 (Pubitemid 37490964)
34. Canet-Avilés RM, Wilson MA, Miller DW et al (2004) The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc Natl Acad Sci USA 101:9103-9108 (Pubitemid 38781618)
35. Martinat C, Shendelman S, Jonason A et al (2004) Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism. PLoS Biol 2:e327 (Pubitemid 40280475)
36. Taira T, Saito Y, Niki T, Iguchi-Ariga SM, Takahashi K, Ariga H (2004) DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep 5:213-218 (Pubitemid 38401204)
37. Junn E, Taniguchi H, Jeong BS, Zhao X, Ichijo H, Mouradian MM (2005) Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death. Proc Natl Acad Sci USA 102:9691-9696 (Pubitemid 40981742)
38. Lev N, Ickowicz D, Melamed E, Offen D (2008) Oxidative insults induce DJ-1 upregulation and redistribution: implications for neuroprotection. Neurotoxicology 29:397-405
39. Lev N, Ickowicz D, Barhum Y, Lev S, Melamed E, Offen D (2009) DJ-1 protects against dopamine toxicity. J Neural Transm 116:151-160
40. Yu HH, Xu Q, Chen HP et al (2013) Stable overexpression of DJ-1 protects H9c2 cells against oxidative stress under a hypoxia condition. Cell Biochem Funct doi. doi: 10.1002/cbf.2949