Intensity-modulated and hypofractionated simultaneous integrated boost adjuvant breast radiation employing statics ports of tomotherapy (TomoDirect): A prospective phase II trial

Journal of Cancer Research and Clinical Oncology

Volumn 140, Issue 1, 2014, Pages 167-177

  Franco, Pierfrancesco ^a   Zeverino, Michele ^a   Migliaccio, Fernanda ^a   Cante, Domenico ^a   Sciacero, Piera ^a   Casanova Borca, Valeria ^a   Torielli, Paolo ^a   Arrichiello, Cecilia ^a   Girelli, Giuseppe ^a   La Porta, Maria Rosa ^a   Tofani, Santi ^a   Numico, Gianmauro ^a   Ricardi, Umberto ^b  

^a Medical Physics Department   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Adjuvant breast radiotherapy; Breast cancer; IGRT; IMRT; SIB; Simultaneous integrated boost; TomoDirect; Tomotherapy

Indexed keywords

ADULT; ARTICLE; BREAST CANCER; CANCER CONTROL; DOSIMETRY; FATIGUE; FOLLOW UP; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MAJOR CLINICAL STUDY; MIDDLE AGED; PARTIAL MASTECTOMY; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIOTHERAPY UNIT; SIMULTANEOUS INTEGRATED BOOST; SKIN TOXICITY; TOMOTHERAPY; TREATMENT OUTCOME;

EID: 84892678129     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-013-1560-8     Document Type: Article

References (46)

1. Bantema-Joppe EJ, Schilstra C, de Bock GH, Dolsma WV, Busz DM, Langendijk JA, Maduro JH (2012) Simultaneous integrated boost irradiation after breast conserving surgery: physician-rated toxicity and cosmetic outcome at 30 months' follow up. Int J Radiat Oncol Biol Phys 83(4):e471-e477
2. Barnett GC, Wilkinson JS, Moody A, Wilson CB, Twyman N, Wishart GC, Burnet NG, Coles CE (2012) Randomized controlled trial of forward-planned intensity modulated-radiotherapy for early breast cancer: interim results at 2 years. Int J Radiat Oncol Biol Phys 82(2):715-723
3. Bartelink H, Horiot JC, Poortmans PM, Struikmans H, Van den Bogaert W, Fourquet A, Jager JJ, Hoogenraad WJ, Oei SB, Warlam-Rodenhuis CC, Pierart M, Colette L (2007) Impact of a higher radiation dose on local control and survival in breast-conserving therapy of early breast cancer: 10 years results of the randomized boost versus no boost EORTC 22881-10882 trial. J Clin Oncol 25(22):3259-3265 (Pubitemid 47325610)
4. Borca VC, Franco P, Catuzzo P, Migliaccio F, Zenone F, Aimonetto S, Peruzzo A, Pasquino M, Russo G, La Porta MR, Cante D, Sciacero P, Girelli G, Ricardi U, Tofani S (2012) Does TomoDirect 3DCRT represent a suitable option for post-operative whole breast irradiation? A hypothesis-generating pilot study. Radiat Oncol 7:211
5. Cante D, Rosa La Porta M, Casanova-Borca V, Sciacero P, Girelli G, Pasquino M, Franco P, Ozzello F (2011) Accelerated hypofractionated adjuvant whole breast radiotherapy with concomitant photon boost after conserving surgery for early breast cancer: a prospective evaluation on 463 patients. Breast J 17(6):586-593
6. Cante D, Franco P, Sciacero P, Girelli G, Marra AM, Pasquino M, Russo G, Borca VC, Mondini G, Paino O, Barmasse R, Tofani S, Numico G, La Porta MR, Ricardi U (2013) Five-year results of a prospective case series of accelerated hypofractionated whole breast radiation with concomitant boost to the tumor bed after conserving surgery for early breast cancer. Med Oncol 30(2):518
7. Catuzzo P, Zenone F, Aimonetto S, Peruzzo A, Casanova Borca V, Pasquino M, Franco P, La Porta MR, Ricardi U (2012) Technical note: patient-specific quality assurance methods for TomoDirect(TM) whole breast treatment delivery. Med Phys 39(7):4073-4078
8. Chadha M, Woode R, Sillanpaa J, Lucido D, Boolbol SK, Kirstein L, Osborne MP, Feldman S, Harrison LB (2013) Early-stage breast cancer treated with 3-week accelerated whole-breast radiation therapy and concomitant boost. Int J Radiat Oncol Biol Phys 86(1):40-44
9. Coles C, Yarnold J, IMPORT Trials Management Group (2006) The IMPORT trials are launched (September 2006). Clin Oncol 18(8):587-590 (Pubitemid 44309271)
10. Cox JD, Stetz J, Pajak TF (1995) Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys 31(5):1341-1346
11. Donovan E, Bleakley N, Denholm E, Evans P, Gothard L, Hanson J, Peckitt C, Reise S, Ross G, Sharp G, Symonds-Tayler R, Tait D, Yarnold J, Breast Technology Group (2007) Randomised trial of standard 2D radiotherapy (RT) versus intensity modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy. Radiother Oncol 82(3):254-264 (Pubitemid 46341474)
12. Early Breast Cancer Trialists' Collaborative Group (2005) Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15 years survival: an overview of the randomized trials. Lancet 366(9503):2087-2106
13. Fayers PM, Aarson NK, Bjordal K, Curran D, Groenvold M, On behalf of the EORTC quality of life study group (1999) EORTC QLQ-C30 scoring manual, 2nd edn. EORTC, Brussels
14. Fiandra C, Filippi AR, Catuzzo P, Botticella A, Ciammella P, Franco P, Borca VC, Ragona R, Tofani S, Ricardi U (2012) Different IMRT solutions vs 3D-conformal radiotherapy in early stage Hodgkin's Lymphoma: dosimetric comparison and clinical considerations. Radiat Oncol 7:186
15. Fowler JF (2010) 21 years of biologically effective dose. Br J Radiol 83(991):554-568
16. Franco P, Ricardi U (2012) TomoDirect to deliver static angle tomotherapy treatments. J Nucl Med Radiat Ther 3:5
17. Franco P, Catuzzo P, Cante D, La Porta MR, Sciacero P, Girelli G, Casanova Borca V, Pasquino M, Numico G, Tofani S, Meloni T, Ricardi U, Ozzello F (2011) TomoDirect: an efficient means to deliver radiation at static angles with tomotherapy. Tumori 97(4):498-502
18. Franco P, Zeverino M, Migliaccio F, Sciacero P, Cante D, Casanova Borca V, Torielli P, Arrichiello C, Girelli G, Numico G, La Porta MR, Tofani S, Ricardi U (2013) Intensity-modulated adjuvant whole breast radiation delivered with static angle tomotherapy (TomoDirect): a prospective case series. J Cancer Res Clin Oncol 139(11):1927-1936
19. Freedman GM, Li T, Nicolaou N, Chen Y, Ma CC, Anderson PR (2009) Breast intensity-modulated radiation therapy reduces time spent with acute dermatitis for women of all breast sizes during radiation. Int J Radiat Oncol Biol Phys 74(3):689-694
20. Freedman GM, Anderson PR, Bleicher RJ, Litwin S, Li T, Swaby RF, Ma CM, Li J, Sigurdson ER, Watkins-Bruner D, Morrow M, Goldstein LJ (2012) Five-year local control in a phase II study of hypofractionated intensity modulated radiation therapy with an incorporated boost for early stage breast cancer. Int J Radiat Oncol Biol Phys 84(4):888-893
21. Freedman GM, White JR, Arthur DW, Li XA, Vicini F (2013) Accelerated fractionation with a concurrent boost for early stage breast cancer. Radiother Oncol 106(1):15-20
22. Harnett A (2010) Fewer fractions of adjuvant external beam radiotherapy for early breast cancer are safe and effective and can now be the standard of care. Why the UK's NICE accepts fewer fractions as the standard of care for adjuvant radiotherapy in early breast cancer. Breast 19(3):159-162
23. Higher-dose radiation therapy or standard radiation therapy in treating patients with early-stage breast cancer that was removed by surgery. RTOG 1005. Located at www.cancer.gov/clinicaltrials/seach/view?cdrid=700069, Accessed 3 Sept 2013
24. Hijal T, Fourniez-Bodoz N, Castro-Pena P, Kirova YM, Zefkili S, Bollet MA, Dendale R, Campana F, Fourquet A (2010) Simultaneous integrated boost in breast conserving treatment of the breast: a dosimetric comparison of helical and three-dimensional conformal radiotherapy. Radiother Oncol 94(3):300-306
25. Holloway CL, Panet-Raymond V, Olivotto I (2010) Hypofractionation should be the new 'standard' for radiation therapy after breast conserving surgery. Breast 19(3):163-167
26. Hong L, Hunt M, Chui C, Spirou S, Forster K, Lee H, Yahalom J, Kutcher GJ, McCormick B (1999) Intensity-modulated tangential beam irradiation of the intact breast. Int J Radiat Oncol Biol Phys 44(5):1155-1164 (Pubitemid 29342918)
27. James ML, Lehman M, Hider PN, Jeffery M, Hickey BE, Francis DP (2008) Fraction size in radiation treatment for breast conservation in early breast cancer. Cochrane Database Syst Rev 3:CD003860
28. Keller LM, Sopka DM, Li T, Klayton T, Li J, Anderson PR, Bleicher RJ, Sigurdson ER, Freedman GM (2012) Five-year results of whole breast intensity modulated radiation therapy for the treatment of early stage breast cancer: the Fox Chase Cancer Center Experience. Int J Radiat Oncol Biol Phys 84(4):881-887
29. Lievens Y (2010) Hypofractionated breast radiotherapy: financial and economic consequences. Breast 19(3):192-197
30. Mannino M, Yarnold JR (2009) Shorter fractionation schedules in breast cancer radiotherapy: clinical and economic implications. Eur J Cancer 45(5):730-731
31. Murai T, Shibamoto Y, Manabe Y, Murata R, Sugie C, Hayashi A, Ito H, Miyoshi Y (2013) Intensity-modulated radiation therapy using static ports of tomotherapy (TomoDirect): comparison with the TomoHelical mode. Radiat Oncol 8:68
32. National Cancer Institute Cancer Therapy Evaluation Program (2013) Common toxicity criteria for adverse events. 2013 Version 4.02. Available at http://ctep.cancer.gov. Accessed September 2013
33. Osoba D, Rodrigues G, Myles J, Zee B, Pater J (1998) Interpreting the significance of changes in health-related quality-of-life scores. J Clin Oncol 16(1):139-144 (Pubitemid 28041591)
34. Pignol JP, Olivotto I, Rakovitch E, Gardner S, Sixel K, Beckhman W, Vu TT, Truong P, Ackerman I, Paszat L (2008) A multicenter randomized trial of breast intensity modulated radiation therapy to reduce acute radiation dermatitis. J Clin Oncol 26(13):2085-2092
35. Poortmans P (2007) Evidence-based radiation oncology. Breast cancer. Radiother Oncol 84(1):84-101 (Pubitemid 47039179)
36. Romestaing P, Lehingue Y, Carrie C, Coquard R, Montbarbon X, Ardiet JM, Mamelle N, Gerard JP (1997) Role of a 10-Gy boost in the conservative treatment of early breast cancer: results of a randomized clinical trial in Lyon, France. J Clin Oncol 15(3):963-968 (Pubitemid 27106278)
37. Rose MA, Olivotto IA, Cady B, Koufman C, Osteen R, Silver B, Recht A, Harris JR (1989) Conservative surgery and radiation therapy for early stage breast cancer: long-term cosmetic results. Arch Surg 124(2):153-157 (Pubitemid 19059735)
38. Schubert LK, Gondi V, Sengbush E, Westerly DC, Soisson ET, Paliwal BR, Mackie TR, Metha MP, Patel RR, Tomé WA, Cannon GM (2011) Dosimetric comparison of left-sided whole breast irradiation with 3DCRT, forward-planned IMRT, inverse-planned IMRT, helical tomotherapy and topotherapy. Radiother Oncol 100(2):241-246
39. Simon R (1989) Optimal two-stage designs for phase II clinical trials. Control Clin Trials 10(1):1-10 (Pubitemid 19099520)
40. Singla R, King S, Albuquerque K, Creech S, Dogan N (2006) Simultaneous-integrated boost intensity-modulated radiation therapy (SIBIMRT) in the treatment of early-stage left-sided breast carcinoma. Med Dosim 31(3):190-196 (Pubitemid 44189232)
41. The START Trialists' Group, Bentzen SM, Agrawal RK, Aird EG, Barrett JM, Barrett-Lee PJ, Bliss JM, Brown J, Dewar JA, Dobbs HJ, Haviland JS, Hoskin P, Hopwood P, Lawton PA, Magee BJ, Mills J, Morgan DA, Owen JR, Simmons S, Sumo G, Sydenham MA, Venables K, Yarnold JR (2008a) The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomized trial. Lancet Oncol 9(4):331-341
42. The START Trialists' Group, Bentzen SM, Agrawal RK, Aird EG, Barrett JM, Barrett-Lee PJ, Bliss JM, Brown J, Dewar JA, Dobbs HJ, Haviland JS, Hoskin P, Hopwood P, Lawton PA, Magee BJ, Mills J, Morgan DA, Owen JR, Simmons S, Sumo G, Sydenham MA, Venables K, Yarnold JR (2008b) The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomized trial. Lancet 371(9618):1098-1107
43. van der Laan HP, Dolsma WV, Maduro JH, Korevaar EW, Hollander M, Langendijk JA (2007) Three-dimensional conformal simultaneously integrated boost technique for breast-conserving radiotherapy. Int J Radiat Oncol Biol Phys 68(4):1018-1023 (Pubitemid 47048573)
44. Van Parijs H, Miedema G, Vinh-Hung V, Verbanck S, Adriaenssens N, Kerkhove D, Reynders T, Schuermans D, Leysen K, Hanon S, Van Camp G, Vincken W, Storme G, Verellen D, De Ridder M (2012) Short course radiotherapy with simultaneous integrated boost for stage I-II breast cancer, early toxicities of a randomized trial. Radiat Oncol 7:80
45. Whelan TJ, Pignol JP, Levine MN, Julian JA, MacKenzie R, Parpia S, Shelley W, Grimard L, Bowen J, Lukka H, Perera F, Fyles A, Schneider K, Gulavita S, Freeman C (2010) Long-term results of hypofractionated radiation therapy for breast cancer. N Engl J Med 362(6):513-520
46. Yarnold J, Ashton A, Bliss J, Homewood J, Harper C, Hanson J, Haviland J, Bentzen S, Owen R (2005) Fractionation sensitivity and dose response of late adverse effects in the breast after radiotherapy for early breast cancer: long-term results of a randomized trial. Radiother Oncol 75(1):9-17 (Pubitemid 40616788)