Five-year results of whole breast intensity modulated radiation therapy for the treatment of early stage breast cancer: The fox chase cancer center experience

International Journal of Radiation Oncology Biology Physics

Volumn 84, Issue 4, 2012, Pages 881-887

  Keller, Lanea M M ^a   Sopka, Dennis M ^a   Li, Tianyu ^a   Klayton, Tracy ^a   Li, Jinsheng ^a   Anderson, Penny R ^a   Bleicher, Richard J ^a   Sigurdson, Elin R ^a   Freedman, Gary M ^b  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Breast cancer; IMRT

Indexed keywords

CHEMOTHERAPY; COSMETICS; DERMATOLOGY; DISEASES; MULTIVARIANT ANALYSIS; TUMORS;

BREAST CANCER; EARLY-STAGE BREAST CANCER; ENDOCRINE THERAPY; IMRT; INTENSITY-MODULATED RADIATION THERAPY; LOCOREGIONAL RECURRENCE; METHODS AND MATERIALS; MULTI VARIATE ANALYSIS;

RADIOTHERAPY;

ANTINEOPLASTIC AGENT;

ADJUVANT THERAPY; ADULT; BREAST CANCER; BREAST FIBROSIS; CANCER ADJUVANT THERAPY; CANCER CENTER; CANCER HORMONE THERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CONFERENCE PAPER; EDEMA; ERYTHEMA; ESTHETICS; FEMALE; FOLLOW UP; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MAJOR CLINICAL STUDY; PHYSICIAN; PRIORITY JOURNAL; RADIATION DOSE; TELANGIECTASIA; TREATMENT OUTCOME; AGED; ARTICLE; BREAST; BREAST TUMOR; HISTOLOGY; METHODOLOGY; MIDDLE AGED; ORGAN SIZE; PATHOLOGY; PROSPECTIVE STUDY; SECOND CANCER; SEGMENTAL MASTECTOMY; TUMOR RECURRENCE; UNITED STATES;

ADULT; AGED; BREAST; BREAST NEOPLASMS; CANCER CARE FACILITIES; FEMALE; HUMANS; MASTECTOMY, SEGMENTAL; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; NEOPLASMS, SECOND PRIMARY; ORGAN SIZE; PHILADELPHIA; PROSPECTIVE STUDIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY, INTENSITY-MODULATED; TREATMENT OUTCOME;

EID: 84872019803     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2012.01.069     Document Type: Conference Paper

References (20)

1. National Comprehensive Cancer Network. NCCN practice guidelines for breast cancer. http://www.nccn.org/professionals/physician-gls/PDF/breast.pdf. Retrieved November 2011.
2. Fisher B AS, Bryant J, et al. Twenty year follow-up of a randomized study comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002; 347:1233-1241.
3. Fisher B DJ, Wolmark N, et al. Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from the National Surgical Adjuvant Breast and Bowel Project B-17. J Clin Oncol. 1998; 16:441-452.
4. Early Breast Cancer Trialists Collaborative Group. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10 801 women in 17 randomised trials. Lancet 2011; 378(9804): 1707-1716.
5. Bucholz TA GE, Bice WS, et al. Dosimteric analysis of intact breast irradiation in off-axis planes. Int J Radiat Oncol Biol Phys. 1997; 39: 261-267.
6. Das IJ CC, Fein DA, et al. Patterns of dose variability in radiation prescription of breast cancer. Radiother Oncol. 1997; 44:83-89.
7. Back M, Guerrieri M, Wratten C, et al. Impact of radiation therapy on acute toxicity in breast conservation therapy for early breast cancer. Clin Oncol 2004; 16:12-16.
8. Fisher J, Scott C, Stevens R, et al. Randomized phase III study comparing best supportive care to Biafine as a prophylactic agent for radiation-induced skin toxicity for women undergoing breast irradiation: Radiation Therapy Oncology Group (RTOG) 97-13. Int J Radiat Oncol Biol Phys 2000; 48:1307-1310.
9. Neal AJ, Torr M, Helyer S, et al. Correlation of breast dose heterogeneity with breast size using 3D CT planning and dose-volume histograms. Radiother Oncol 1995; 34:210-218.
10. Pignol JP OI, Rakovitch E, et al. A multicenter randomized trial of breast intensity-modulated radiation therapy to reduce acute radiation dermatitis. J Clin Oncol. 2008; 26:2085-2092.
11. Donovan E, Bleakley N, Denholm E, et al. Randomised trial of standard 2D radiotherapy (RT) versus intensity modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy. Radiother Oncol 2007; 82:254-264.
12. Vicini FA, Sharpe M, Kestin L, et al. Optimizing breast cancer treatment efficacy with intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 2002; 54:1336-1344.
13. Herrick JS, Neill CJ, Rosser PF. A comprehensive clinical 3-dimen-sional dosimetric analysis of forward planned IMRT and conventional wedge planned techniques for intact breast radiotherapy. Med Dosim 2008; 33:62-70.
14. Mihai A, Rakovitch E, Sixel K, et al. Inverse vs. forward breast IMRT planning. Med Dosim 2005; 30:149-154.
15. Harsolia A, Kestin L, Grills I, et al. In clinical toxicities compared with conventional wedge-based breast radiotherapy. Int J Radiat Oncol Biol Phys 2007; 68:1375-1380.
16. Freedman GM, Li T, Nicolaou N, et al. Breast intensity-modulated radiation therapy reduces time spent with acute dermatitis for women of all breast sizes during radiation. Int J Radiat Oncol Biol Phys 2009; 74:689-694.
17. Li JS, Freedman GM, Price R, et al. Clinical implementation of intensity-modulated tangential beam irradiation for breast cancer. Med Phys 2004; 31:1023-1031.
18. Barnett GC, Wilkinson JS, Moody AM, et al. Randomized controlled trial of forward-planned intensity-modulated radiotherapy for early breast cancer: interim results at 2 years. Int J Radiat Oncol Biol Phys 2012; 82:715-723.
19. Descovich M, Fowble B, Bevan A, et al. Comparison between hybrid direct aperature optimized intensity-modulated radiotherapy and forward planning intensity-modulated radiotherapy for whole breast irradiation. Int J Radiat Oncol Biol Phys 2010; 76:91-99.
20. Mayo CS, Urie MM, Fitzgerald TJ. Hybrid IMRT plans-concurrently treating conventional and IMRT beams for improved breast irradiation and reduced planning time. Int J Radiat Oncol Biol Phys 2005; 61:922-932.