STAT1 negatively regulates spatial memory formation and mediates the memory-impairing effect of Aβ

Neuropsychopharmacology

Volumn 39, Issue 3, 2014, Pages 746-758

  Hsu, Wei Lun ^a   Ma, Yun Li ^a   Hsieh, Ding You ^a,b   Liu, Yen Chen ^a   Lee, Eminy Hy ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b NATIONAL CHENGCHI UNIVERSITY   (Taiwan)

Author keywords

amyloid beta; CREB; LB1; NMDA receptor subunit; spatial learning and memory; STAT1

Indexed keywords

ACTIN; AMYLOID BETA PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; LAMININ BETA1; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; SCLEROPROTEIN; STAT1 PROTEIN; STAT2 PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOWN REGULATION; HIPPOCAMPAL CA1 REGION; INFLAMMATION; INNATE IMMUNITY; MALE; MEMORY DISORDER; MORRIS WATER MAZE TEST; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SPATIAL LEARNING; SPATIAL MEMORY; TRANSCRIPTION REGULATION; UPREGULATION;

AMYLOID BETA-PEPTIDES; ANIMALS; CREB-BINDING PROTEIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; LAMININ; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, KNOCKOUT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, SMALL INTERFERING; SPACE PERCEPTION; STAT1 TRANSCRIPTION FACTOR;

EID: 84892669282     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.263     Document Type: Article

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