Neuropharmacological modulation of the P3-like event-related potential in a rat two-tone auditory discrimination task with modafinil and NS9283, a positive allosteric modulator of α4β2 nAChRs

Neuropharmacology

Volumn 79, Issue , 2014, Pages 444-455

  Grupe, Morten ^a,b   Grunnet, Morten ^a,b   Laursen, Bettina ^b,c   Bastlund, Jesper Frank ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b H LUNDBECK A S   (Denmark)

^c AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Alpha4beta2; Event related potential; Modafinil; Nicotinic acetylcholine receptor; NS9283; Positive allosteric modulator

Indexed keywords

3 [ (3 PYRIDYL) 1,2,4 OXADIAZOL 5 YL]BENZONITRILE; MODAFINIL; NICOTINIC AGENT; NS 9283; UNCLASSIFIED DRUG; 3-(3-(PYRIDINE-3-YL)-1,2,4-OXADIAZOL-5-YL)BENZONITRILE; BENZHYDRYL DERIVATIVE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4BETA2; OXADIAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; WAKEFULNESS PROMOTING AGENT;

ADULT; AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ARTICLE; AUDITORY CORTEX; AUDITORY DISCRIMINATION; CONTROLLED STUDY; DRUG EFFECT; ELECTROENCEPHALOGRAPHY; EVENT RELATED POTENTIAL; EVOKED AUDITORY RESPONSE; HIPPOCAMPUS; LATENT PERIOD; MALE; MEDIAL PREFRONTAL CORTEX; NEUROMODULATION; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; THALAMUS DORSOMEDIAL NUCLEUS; ANIMAL; AUDITORY STIMULATION; BRAIN; DRUG EFFECTS; ELECTRODE IMPLANT; HEARING; METABOLISM; NEUROPSYCHOLOGICAL TEST; PERCEPTIVE DISCRIMINATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

ACOUSTIC STIMULATION; ANIMALS; AUDITORY PERCEPTION; BENZHYDRYL COMPOUNDS; BRAIN; DISCRIMINATION (PSYCHOLOGY); ELECTRODES, IMPLANTED; ELECTROENCEPHALOGRAPHY; EVOKED POTENTIALS, AUDITORY; NEUROPSYCHOLOGICAL TESTS; NICOTINIC AGONISTS; OXADIAZOLES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; TASK PERFORMANCE AND ANALYSIS; TIME FACTORS; WAKEFULNESS-PROMOTING AGENTS;

EID: 84892668317     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.12.008     Document Type: Article

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