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Volumn 73, Issue 17, 2013, Pages 1935-1950

Prucalopride: A review of its use in the management of chronic constipation

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE PLUS MACROGOL 3350 PLUS POTASSIUM CHLORIDE PLUS SODIUM CHLORIDE; LAXATIVE; PLACEBO; PRUCALOPRIDE; RESOTRAN; UNCLASSIFIED DRUG;

EID: 84892622812     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.1007/s40265-013-0140-1     Document Type: Article
Times cited : (23)

References (71)
  • 1
    • 79960420661 scopus 로고    scopus 로고
    • Diagnosis and treatment of chronic constipation: A European perspective
    • Tack J, Müller-Lissner S, Stanghellini V, et al. Diagnosis and treatment of chronic constipation: a European perspective. Neu-rogastroenterol Motil. 2011;23(8):697-710.
    • (2011) Neu-rogastroenterol Motil. , vol.23 , Issue.8 , pp. 697-710
    • Tack, J.1    Müller-Lissner, S.2    Stanghellini, V.3
  • 3
    • 84855541533 scopus 로고    scopus 로고
    • Prucalopride: Safety, efficacy and potential applications
    • Quigley EMM. Prucalopride: safety, efficacy and potential applications. Ther Adv Gastroenterol. 2012;5(1):23-30.
    • (2012) Ther Adv Gastroenterol. , vol.5 , Issue.1 , pp. 23-30
    • Quigley, E.M.M.1
  • 5
    • 84859238171 scopus 로고    scopus 로고
    • Chronic constipation: Current treatment options
    • Liu LWC. Chronic constipation: current treatment options. Can J Gastroenterol. 2011;25 Suppl B:22B-8B.
    • (2011) Can J Gastroenterol. , vol.25 , Issue.SUPPL. B
    • Liu, L.W.C.1
  • 7
    • 0031950380 scopus 로고    scopus 로고
    • Effect of a novel prokinetic drug, R093877, on gastrointestinal transit in healthy volunteers
    • Emmanuel AV, Kamm MA, Roy AJ, et al. Effect of a novel prokinetic drug, R093877, on gastrointestinal transit in healthy volunteers. Gut. 1998;42(4):511-6.
    • (1998) Gut. , vol.42 , Issue.4 , pp. 511-516
    • Emmanuel, A.V.1    Kamm, M.A.2    Roy, A.J.3
  • 8
    • 0032589966 scopus 로고    scopus 로고
    • Effect of prucalopride, a new enterokinetic agent, on gastrointestinal transit and anorectal function in healthy volunteers
    • Poen AC, Felt-Bersma RJF, Van Dongen PAM, et al. Effect of prucalopride, a new enterokinetic agent, on gastrointestinal transit and anorectal function in healthy volunteers. Aliment Pharmacol Ther. 1999;13(11):1493-7.
    • (1999) Aliment Pharmacol Ther. , vol.13 , Issue.11 , pp. 1493-1497
    • Poen, A.C.1    Felt-Bersma, R.J.F.2    Van Dongen, P.A.M.3
  • 11
    • 84892574183 scopus 로고    scopus 로고
    • Prucalopride decreases esophageal acid exposure and accelerates gastric emptying in healthy subjects [abstract no. 745]
    • Kessing BF, Smout AJ, Bennink RJ, et al. Prucalopride decreases esophageal acid exposure and accelerates gastric emptying in healthy subjects [abstract no. 745]. Gastroenterology. 2013;144(5 Suppl 1):S134.
    • (2013) Gastroenterology. , vol.144 , Issue.5 SUPPL. 1
    • Kessing, B.F.1    Smout, A.J.2    Bennink, R.J.3
  • 12
    • 72449142246 scopus 로고    scopus 로고
    • Cardiovascular safety of prucalopride in healthy subjects: Results from two randomized double-blind placebo-controlled cross-over trials [abstract no. T1265]
    • Boyce MJ, Kerstens R, Beyens G, et al. Cardiovascular safety of prucalopride in healthy subjects: results from two randomized, double-blind, placebo-controlled, cross-over trials [abstract no. T1265]. Gastroenterology. 2009;136(5 Suppl 1):A535.
    • (2009) Gastroenterology. , vol.136 , Issue.5 SUPPL. 1
    • Boyce, M.J.1    Kerstens, R.2    Beyens, G.3
  • 13
    • 84855513343 scopus 로고    scopus 로고
    • Assessment of the cardiac safety of prucalopride in healthy volunteers: A randomized, double-blind, placebo-and positive-controlled thorough QT study
    • Mendzelevski B, Ausma J, Chanter DO, et al. Assessment of the cardiac safety of prucalopride in healthy volunteers: a randomized, double-blind, placebo-and positive-controlled thorough QT study. Br J Clin Pharmacol. 2012;73(2):203-9.
    • (2012) Br J Clin Pharmacol. , vol.73 , Issue.2 , pp. 203-209
    • Mendzelevski, B.1    Ausma, J.2    Chanter, D.O.3
  • 14
    • 0037540068 scopus 로고    scopus 로고
    • Prucalopride is effective in patients with severe chronic constipation in whom laxatives fail to provide adequate relief: Results of a double-blind, placebo-controlled clinical trial
    • Coremans G, Kerstens R, De Pauw M, et al. Prucalopride is effective in patients with severe chronic constipation in whom laxatives fail to provide adequate relief: results of a double-blind, placebo-controlled clinical trial. Digestion. 2003;67(1-2):82-9.
    • (2003) Digestion. , vol.67 , Issue.1-2 , pp. 82-89
    • Coremans, G.1    Kerstens, R.2    De Pauw, M.3
  • 15
    • 0035121508 scopus 로고    scopus 로고
    • Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder
    • Bouras EP, Camilleri M, Burton DD, et al. Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder. Gastroenterology. 2001;120(2):354-60.
    • (2001) Gastroenterology. , vol.120 , Issue.2 , pp. 354-360
    • Bouras, E.P.1    Camilleri, M.2    Burton, D.D.3
  • 16
    • 0036109163 scopus 로고    scopus 로고
    • Effects of prucalopride on colonic transit, anorectal function and bowel habits in patients with chronic constipation
    • Sloots CEJ, Poen AC, Kerstens R, et al. Effects of prucalopride on colonic transit, anorectal function and bowel habits in patients with chronic constipation. Aliment Pharmacol Ther. 2002;16(4):759-67.
    • (2002) Aliment Pharmacol Ther. , vol.16 , Issue.4 , pp. 759-767
    • Sloots, C.E.J.1    Poen, A.C.2    Kerstens, R.3
  • 17
    • 0036024222 scopus 로고    scopus 로고
    • Prucalopride, a systemic enterokinetic, for the treatment of constipation
    • Emmanuel AV, Roy AJ, Nicholls TJ, et al. Prucalopride, a systemic enterokinetic, for the treatment of constipation. Aliment Pharmacol Ther. 2002;16(7):1347-56.
    • (2002) Aliment Pharmacol Ther. , vol.16 , Issue.7 , pp. 1347-1356
    • Emmanuel, A.V.1    Roy, A.J.2    Nicholls, T.J.3
  • 18
    • 84856995264 scopus 로고    scopus 로고
    • Prucalopride improves bowel function and colonic transit time in patients with constipation [abstract no. Mo1326]
    • Emmanuel AV, Kerstens R, Vandeplassche LM. Prucalopride improves bowel function and colonic transit time in patients with constipation [abstract no. Mo1326]. Gastroenterology. 2011;140 (5 Suppl 1):S612.
    • (2011) Gastroenterology. , vol.140 , Issue.5 SUPPL. 1
    • Emmanuel, A.V.1    Kerstens, R.2    Vandeplassche, L.M.3
  • 19
    • 0035967979 scopus 로고    scopus 로고
    • The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound
    • Briejer MR, Bosmans J-P, Van Daele P, et al. The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. Eur J Pharmacol. 2001;423(1):71-83.
    • (2001) Eur J Pharmacol. , vol.423 , Issue.1 , pp. 71-83
    • Briejer, M.R.1    Bosmans, J.-P.2    Van Daele, P.3
  • 21
    • 33747059826 scopus 로고    scopus 로고
    • Investigation of serotonin type 4 receptor expression in human and non-human primate gastrointestinal samples
    • Mader R, Kocher T, Haier J, et al. Investigation of serotonin type 4 receptor expression in human and non-human primate gastrointestinal samples. Eur J Gastroenterol Hepatol. 2006;18(9): 945-50.
    • (2006) Eur J Gastroenterol Hepatol. , vol.18 , Issue.9 , pp. 945-950
    • Mader, R.1    Kocher, T.2    Haier, J.3
  • 22
    • 0033709510 scopus 로고    scopus 로고
    • 4 receptors on cholinergic nerves involved in contractility of canine and human large intestine longitudinal muscle
    • 4 receptors on cholinergic nerves involved in contractility of canine and human large intestine longitudinal muscle. Br J Pharmacol. 2000;131(5):927-32.
    • (2000) Br J Pharmacol. , vol.131 , Issue.5 , pp. 927-932
    • Prins, N.H.1    Akkermans, L.M.2    Lefebvre, R.A.3
  • 23
    • 0033998810 scopus 로고    scopus 로고
    • 4 receptors in the human isolated large intestinal circular muscle
    • 4 receptors in the human isolated large intestinal circular muscle. Br J Pharmacol. 2000;129(8): 1601-8.
    • (2000) Br J Pharmacol. , vol.129 , Issue.8 , pp. 1601-1608
    • Prins, N.H.1    Shankley, N.P.2    Welsh, N.J.3
  • 24
    • 0032772797 scopus 로고    scopus 로고
    • 4 receptors mediating relaxation of canine isolated rectum circular smooth muscle
    • 4 receptors mediating relaxation of canine isolated rectum circular smooth muscle. Br J Pharmacol. 1999;127(6):1431-7.
    • (1999) Br J Pharmacol. , vol.127 , Issue.6 , pp. 1431-1437
    • Prins, N.H.1    Van Haselen, J.F.W.R.2    Lefebvre, R.A.3
  • 25
    • 0034768022 scopus 로고    scopus 로고
    • Effects of the enteroki-netic prucalopride (R093877) on colonic motility in fasted dogs
    • Briejer MR, Prins NH, Schuurkes JAJ. Effects of the enteroki-netic prucalopride (R093877) on colonic motility in fasted dogs. Neurogastroenterol Motil. 2001;13(5):465-72.
    • (2001) Neurogastroenterol Motil. , vol.13 , Issue.5 , pp. 465-472
    • Briejer, M.R.1    Prins, N.H.2    Schuurkes, J.A.J.3
  • 26
    • 33845324073 scopus 로고    scopus 로고
    • The action of the novel gastrointestinal prokinetic prucalopride on the HERG K channel and the common T897 polymorph
    • Chapman H, Pasternack M. The action of the novel gastrointestinal prokinetic prucalopride on the HERG K channel and the common T897 polymorph. Eur J Pharmacol. 2007;554(2-3): 98-105.
    • (2007) Eur J Pharmacol. , vol.554 , Issue.2-3 , pp. 98-105
    • Chapman, H.1    Pasternack, M.2
  • 27
    • 0035197735 scopus 로고    scopus 로고
    • Gastrointestinal prokinetic drugs have different affinity for the human cardiac human ether-À-gogo K channel
    • Potet F, Bouyssou T, Escande D, et al. Gastrointestinal prokinetic drugs have different affinity for the human cardiac human ether-à-gogo K channel. J Pharmacol Exp Ther. 2001;299(3): 1007-12.
    • (2001) J Pharmacol Exp Ther. , vol.299 , Issue.3 , pp. 1007-1012
    • Potet, F.1    Bouyssou, T.2    Escande, D.3
  • 28
    • 85081803624 scopus 로고    scopus 로고
    • European Medicines Agency. Resolor (prucalopride): EU public assessment report. Accessed 8 Oct 2013
    • European Medicines Agency. Resolor (prucalopride): EU public assessment report. 2009. http://www.ema.europa.eu/docs/en-GB/document-library/EPAR-Public- assessment-report/human/001 012/WC500053997.pdf (Accessed 8 Oct 2013).
    • (2009)
  • 29
    • 15744373380 scopus 로고    scopus 로고
    • Electrophysiological effects of prucalopride, a novel enterokinetic agent, on isolated atrial myocytes from patients treated with b-adrenoceptor antagonists
    • Pau D, Workman AJ, Kane KA, et al. Electrophysiological effects of prucalopride, a novel enterokinetic agent, on isolated atrial myocytes from patients treated with b-adrenoceptor antagonists. J Pharmacol Exp Ther. 2005;313(1):146-53.
    • (2005) J Pharmacol Exp Ther. , vol.313 , Issue.1 , pp. 146-153
    • Pau, D.1    Workman, A.J.2    Kane, K.A.3
  • 32
    • 31444447595 scopus 로고    scopus 로고
    • 4 receptor-induced responses: Fading of the response and influence of development
    • 4 receptor-induced responses: fading of the response and influence of development. Br J Pharmacol. 2006;147(2):140-57.
    • (2006) Br J Pharmacol. , vol.147 , Issue.2 , pp. 140-157
    • De Maeyer, J.H.1    Straetemans, R.2    Schuurkes, J.A.J.3
  • 33
    • 78650623060 scopus 로고    scopus 로고
    • Kinetics and absolute oral bioavailability of prucalopride [abstract no. S1331]
    • Van de Velde VJ, Ausma J, Vandeplassche L. I.V. kinetics and absolute oral bioavailability of prucalopride [abstract no. S1331]. Gastroenterology. 2010;138(5 Suppl 1):S230.
    • (2010) Gastroenterology. , vol.138 , Issue.5 SUPPL. 1
    • Van De Velde, V.J.1    Ausma, J.2    Vandeplassche, L.I.V.3
  • 34
    • 84866483978 scopus 로고    scopus 로고
    • Food does not affect the oral bioavailability of prucalopride [abstract no. T1270]
    • Van de Velde VJ, Ausma J, Vandeplassche L. Food does not affect the oral bioavailability of prucalopride [abstract no. T1270]. Gastroenterology. 2009;136(5 Suppl 1):A536.
    • (2009) Gastroenterology. , vol.136 , Issue.5 SUPPL. 1
    • Van De Velde, V.J.1    Ausma, J.2    Vandeplassche, L.3
  • 35
    • 78650623060 scopus 로고    scopus 로고
    • Comparative pharmacokinetics of prucalopride in healthy young and elderly subjects [abstract no. S1330]
    • Van de Velde VJ, Ausma J, Vandeplassche L. Comparative pharmacokinetics of prucalopride in healthy young and elderly subjects [abstract no. S1330]. Gastroenterology. 2010;138(5 Suppl 1):S230.
    • (2010) Gastroenterology. , vol.138 , Issue.5 SUPPL. 1
    • Van De Velde, V.J.1    Ausma, J.2    Vandeplassche, L.3
  • 36
    • 84867903411 scopus 로고    scopus 로고
    • Pharmacokinetics of single and repeated oral doses of prucalopride in healthy Chinese volunteers
    • Chen X, Jiang J, Liu T, et al. Pharmacokinetics of single and repeated oral doses of prucalopride in healthy Chinese volunteers. Int J Clin Pharmacol Ther. 2012;50(11):797-804.
    • (2012) Int J Clin Pharmacol Ther. , vol.50 , Issue.11 , pp. 797-804
    • Chen, X.1    Jiang, J.2    Liu, T.3
  • 38
    • 85081810398 scopus 로고    scopus 로고
    • TM (prucalopride) tablets: Canadian prescribing information. Accessed 8 Oct 2013
    • TM (prucalopride) tablets: Canadian prescribing information. 2012. http://www.hc-sc.gc.ca (Accessed 8 Oct 2013).
    • (2012)
  • 40
    • 84872301145 scopus 로고    scopus 로고
    • Effect of renal impairment on the pharmacokinetics of prucalopride: A single-dose open-label phase i study
    • Smith WB, Mannaert E, Verhaeghe T, et al. Effect of renal impairment on the pharmacokinetics of prucalopride: a single-dose open-label phase I study. Drug Des Dev Ther. 2012;6:407-15.
    • (2012) Drug des Dev Ther. , vol.6 , pp. 407-415
    • Smith, W.B.1    Mannaert, E.2    Verhaeghe, T.3
  • 41
    • 84876271502 scopus 로고    scopus 로고
    • Effect of prucalopride on the pharmacokinetics of oral contraceptives in healthy women
    • Van de Velde V, Vandeplassche L, Hoppenbrouwers M, et al. Effect of prucalopride on the pharmacokinetics of oral contraceptives in healthy women. Drugs R D. 2013;13(1):43-51.
    • (2013) Drugs R D. , vol.13 , Issue.1 , pp. 43-51
    • Van De Velde, V.1    Vandeplassche, L.2    Hoppenbrouwers, M.3
  • 42
    • 44349130441 scopus 로고    scopus 로고
    • A placebo-controlled trial of prucalopride for severe chronic constipation
    • Camilleri M, Kerstens R, Rykx A, et al. A placebo-controlled trial of prucalopride for severe chronic constipation. N Engl J Med. 2008;358(22):2344- 54.
    • (2008) N Engl J Med. , vol.358 , Issue.22 , pp. 2344-2354
    • Camilleri, M.1    Kerstens, R.2    Rykx, A.3
  • 43
    • 58149084950 scopus 로고    scopus 로고
    • Clinical trial: The efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation-A 12-week, randomized, double-blind, placebo-controlled study
    • Quigley EMM, Vandeplassche L, Kerstens R, et al. Clinical trial: the efficacy, impact on quality of life, and safety and tolerability of prucalopride in severe chronic constipation-a 12-week, randomized, double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2009;29(3):315-28.
    • (2009) Aliment Pharmacol Ther. , vol.29 , Issue.3 , pp. 315-328
    • Quigley, E.M.M.1    Vandeplassche, L.2    Kerstens, R.3
  • 44
    • 61649119045 scopus 로고    scopus 로고
    • Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives
    • Tack J, van Outryve M, Beyens G, et al. Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives. Gut. 2009;58(3):357-65.
    • (2009) Gut. , vol.58 , Issue.3 , pp. 357-365
    • Tack, J.1    Van Outryve, M.2    Beyens, G.3
  • 45
    • 84867496918 scopus 로고    scopus 로고
    • Prucalopride in the treatment of chronic constipation in patients from the Asia-Pacific region: A randomized, double-blind, placebo-controlled study
    • Ke M, Zou D, Yuan Y, et al. Prucalopride in the treatment of chronic constipation in patients from the Asia-Pacific region: a randomized, double-blind, placebo-controlled study. Neurogas-troenterol Motil. 2012;24(11):999-e541.
    • (2012) Neurogas-troenterol Motil. , vol.24 , Issue.11
    • Ke, M.1    Zou, D.2    Yuan, Y.3
  • 46
    • 77955493094 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of prucalopride in elderly patients with chronic constipation
    • e255
    • Müller-Lissner S, Rykx A, Kerstens R, et al. A double-blind, placebo-controlled study of prucalopride in elderly patients with chronic constipation. Neurogastroenterol Motil. 2010;22(9): 991-8, e255.
    • (2010) Neurogastroenterol Motil. , vol.22 , Issue.9 , pp. 991-998
    • Müller-Lissner, S.1    Rykx, A.2    Kerstens, R.3
  • 47
    • 84886295628 scopus 로고    scopus 로고
    • How effective is prucalo-pride for the treatment of chronic constipation? A systematic review and meta-analysis [abstract no. Su2069]
    • Gatta L, Kerstens R, Scarpignato C. How effective is prucalo-pride for the treatment of chronic constipation? A systematic review and meta-analysis [abstract no. Su2069]. Gastroenterol-ogy. 2013;144(5 Suppl 1):S547-8.
    • (2013) Gastroenterol-ogy. , vol.144 , Issue.5 SUPPL. 1
    • Gatta, L.1    Kerstens, R.2    Scarpignato, C.3
  • 48
    • 85081804974 scopus 로고    scopus 로고
    • Efficacy of prucalopride in the treatment of chronic constipation: A systematic review and meta-analysis of randomized controlled trials [abstract]
    • Cheng E. Efficacy of prucalopride in the treatment of chronic constipation: a systematic review and meta-analysis of randomized controlled trials [abstract]. Clin Gastroenterol Hepatol. 2012;10(3):329-30.
    • (2012) Clin Gastroenterol Hepatol. , vol.10 , Issue.3 , pp. 329-330
    • Cheng, E.1
  • 49
    • 84877968844 scopus 로고    scopus 로고
    • Efficacy and safety of oral prucalopride in women with chronic constipation in whom laxatives have failed: An integrated analysis
    • Tack J, Quigley E, Camilleri M, et al. Efficacy and safety of oral prucalopride in women with chronic constipation in whom laxatives have failed: an integrated analysis. United Eur Gastroen-terol J. 2013;1:48-59.
    • (2013) United Eur Gastroen-terol J. , vol.1 , pp. 48-59
    • Tack, J.1    Quigley, E.2    Camilleri, M.3
  • 50
    • 84890227444 scopus 로고    scopus 로고
    • Effect of prucalopride on symptoms of chronic constipation
    • doi:10.1111/nmo.12217
    • Tack J, Stanghellini V, Dubois D, et al. Effect of prucalopride on symptoms of chronic constipation. Neurogastroenterol Motil. 2013;. doi:10.1111/nmo.12217.
    • (2013) Neurogastroenterol Motil.
    • Tack, J.1    Stanghellini, V.2    Dubois, D.3
  • 51
    • 85081803949 scopus 로고    scopus 로고
    • Treatment with prucalopride for chronic constipation improves the symptoms and quality of life of patients in China [abstract no. PGI16]
    • plus poster presented at the International Society for Pharmacoeconomics and Outcomes Research 5th Asia-Pacific Conference; 2-4 Sep 2012; Taipei
    • Ke MY, Zou DW, Yuan YZ, et al. Treatment with prucalopride for chronic constipation improves the symptoms and quality of life of patients in China [abstract no. PGI16]. Value Health. 2012;15(7):A637-8 plus poster presented at the International Society for Pharmacoeconomics and Outcomes Research 5th Asia-Pacific Conference; 2-4 Sep 2012; Taipei.
    • (2012) Value Health. , vol.15 , Issue.7
    • Ke, M.Y.1    Zou, D.W.2    Yuan, Y.Z.3
  • 52
    • 84892617516 scopus 로고    scopus 로고
    • Best response distribution of 12-week treatment with prucalopride (Resolor) in patients with chronic constipation: Combined results of three randomised, double-blind, placebo-controlled phase III trials [abstract no. PWE-075]
    • Stanghellini V, Vandeplassche L, Kerstens R. Best response distribution of 12-week treatment with prucalopride (Resolor) in patients with chronic constipation: combined results of three randomised, double-blind, placebo-controlled phase III trials [abstract no. PWE-075]. Gut. 2011;60 Suppl 1:A159-60.
    • (2011) Gut. , vol.60 , Issue.SUPPL. 1
    • Stanghellini, V.1    Vandeplassche, L.2    Kerstens, R.3
  • 53
    • 78649484435 scopus 로고    scopus 로고
    • Clinical trial: The efficacy of open-label prucalopride treatment in patients with chronic constipation-follow-up of patients from the pivotal studies
    • Camilleri M, Van Outryve MJ, Beyens G, et al. Clinical trial: the efficacy of open-label prucalopride treatment in patients with chronic constipation-follow-up of patients from the pivotal studies. Aliment Pharmacol Ther. 2010;32(9):1113-23.
    • (2010) Aliment Pharmacol Ther. , vol.32 , Issue.9 , pp. 1113-1123
    • Camilleri, M.1    Van Outryve, M.J.2    Beyens, G.3
  • 54
    • 84875861865 scopus 로고    scopus 로고
    • Randomised clinical trial: Macrogol/PEG 3350 ? Electrolytes versus prucalopride in the treatment of chronic constipation: A comparison in a controlled environment
    • Cinca R, Chera D, Gruss H-J, et al. Randomised clinical trial: macrogol/PEG 3350 ? electrolytes versus prucalopride in the treatment of chronic constipation: a comparison in a controlled environment. Aliment Pharmacol Ther. 2013;37(9):876-86.
    • (2013) Aliment Pharmacol Ther. , vol.37 , Issue.9 , pp. 876-886
    • Cinca, R.1    Chera, D.2    Gruss, H.-J.3
  • 55
    • 72049090263 scopus 로고    scopus 로고
    • Safety assessment of prucalopride in elderly patients with constipation: A double-blind, placebo-controlled study
    • e117
    • Camilleri M, Beyens G, Kerstens R, et al. Safety assessment of prucalopride in elderly patients with constipation: a double-blind, placebo-controlled study. Neurogastroenterol Motil. 2009;21(12): 1256-63, e117.
    • (2009) Neurogastroenterol Motil. , vol.21 , Issue.12 , pp. 1256-1263
    • Camilleri, M.1    Beyens, G.2    Kerstens, R.3
  • 56
    • 85081809543 scopus 로고    scopus 로고
    • Movetis. Movetis receives authorisation to market Resolor in Switzerland [media release]; Accessed 8 Oct 2013
    • Movetis. Movetis receives authorisation to market Resolor in Switzerland [media release]; 2010. http://www.movetis.com (Accessed 8 Oct 2013).
    • (2010)
  • 57
    • 84863443935 scopus 로고    scopus 로고
    • Chronic constipation: New diagnostic and treatment approaches
    • Lacy BE, Levenick JM, Crowell M. Chronic constipation: new diagnostic and treatment approaches. Ther Adv Gastroenterol. 2012;5(4):233-47.
    • (2012) Ther Adv Gastroenterol. , vol.5 , Issue.4 , pp. 233-247
    • Lacy, B.E.1    Levenick, J.M.2    Crowell, M.3
  • 58
    • 79958808231 scopus 로고    scopus 로고
    • World Gastroenterology Organisation global guideline: Constipation-A global perspective
    • Lindberg G, Hamid SS, Malfertheiner P, et al. World Gastroenterology Organisation global guideline: constipation-a global perspective. J Clin Gastroenterol. 2011;45(6):483-7.
    • (2011) J Clin Gastroenterol. , vol.45 , Issue.6 , pp. 483-487
    • Lindberg, G.1    Hamid, S.S.2    Malfertheiner, P.3
  • 59
    • 84867785625 scopus 로고    scopus 로고
    • Consensus statement AIGO/SICCR diagnosis and treatment of chronic constipation and obstructed defecation (part II: Treatment)
    • Bove A, Bellini M, Battaglia E, et al. Consensus statement AIGO/SICCR diagnosis and treatment of chronic constipation and obstructed defecation (part II: treatment). World J Gastroenterol. 2012;18(36):4994-5013.
    • (2012) World J Gastroenterol. , vol.18 , Issue.36 , pp. 4994-5013
    • Bove, A.1    Bellini, M.2    Battaglia, E.3
  • 61
    • 84857249153 scopus 로고    scopus 로고
    • Prucalopride
    • Herring C. Prucalopride. Clin Pharmacist. 2011;3(2):55-7.
    • (2011) Clin Pharmacist. , vol.3 , Issue.2 , pp. 55-57
    • Herring, C.1
  • 64
    • 85081808396 scopus 로고    scopus 로고
    • The relation between adverse events on day 1 and pharmacodynamic effects on day 1 of treatment with prucalopride [abstract no. Mo1336]
    • Stanghellini V, Vandeplassche LM, Kerstens R, et al. The relation between adverse events on day 1 and pharmacodynamic effects on day 1 of treatment with prucalopride [abstract no. Mo1336]. Gastroenterology. 2011;140(5 Suppl 1):S615.
    • (2011) Gastroenterology. , vol.140 , Issue.5 SUPPL. 1
    • Stanghellini, V.1    Vandeplassche, L.M.2    Kerstens, R.3
  • 67
    • 84866505136 scopus 로고    scopus 로고
    • Prucalopride: Evaluation of the pharmacokinetics, pharmacodynamics, efficacy and safety in the treatment of chronic constipation
    • Tack J, Corsetti M. Prucalopride: evaluation of the pharmacokinetics, pharmacodynamics, efficacy and safety in the treatment of chronic constipation. Expert Opin Drug Metab Toxicol. 2012;8 (10):1327-35.
    • (2012) Expert Opin Drug Metab Toxicol. , vol.8 , Issue.10 , pp. 1327-1335
    • Tack, J.1    Corsetti, M.2
  • 68
    • 0344492207 scopus 로고    scopus 로고
    • Relationships between preclinical cardiac electrophysiology clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
    • Redfern WS, Carlsson L, Davis AS, et al. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. Cardiovasc Res. 2003;58(1):32-45.
    • (2003) Cardiovasc Res. , vol.58 , Issue.1 , pp. 32-45
    • Redfern, W.S.1    Carlsson, L.2    Davis, A.S.3
  • 69
    • 77957924970 scopus 로고    scopus 로고
    • Efficacy and safety of prucalopride in patients with chronic noncancer pain suffering from opioid-induced constipation
    • Sloots CEJ, Rykx A, Cools M, et al. Efficacy and safety of prucalopride in patients with chronic noncancer pain suffering from opioid-induced constipation. Dig Dis Sci. 2010;55(10): 2912-21.
    • (2010) Dig Dis Sci. , vol.55 , Issue.10 , pp. 2912-2921
    • Sloots, C.E.J.1    Rykx, A.2    Cools, M.3
  • 71
    • 83555168315 scopus 로고    scopus 로고
    • Randomised clinical trial: The efficacy of prucalopride in patients with chronic intestinal pseudo-obstruction-A double-blind, placebo-controlled, cross-over, multiple n = 1 study
    • Emmanuel AV, Kamm MA, Roy AJ, et al. Randomised clinical trial: the efficacy of prucalopride in patients with chronic intestinal pseudo-obstruction-a double-blind, placebo-controlled, cross-over, multiple n = 1 study. Aliment Pharmacol Ther. 2012;35(1):48-55.
    • (2012) Aliment Pharmacol Ther. , vol.35 , Issue.1 , pp. 48-55
    • Emmanuel, A.V.1    Kamm, M.A.2    Roy, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.