Induction of amphiregulin by p53 promotes apoptosis via control of microRNA biogenesis in response to DNA damage

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 2, 2014, Pages 717-722

  Taira, Naoe ^a   Yamaguchi, Tomoko ^a   Kimura, Junko ^b   Lu, Zheng Guang ^b   Fukuda, Shinji ^c   Higashiyama, Shigeki ^c   Ono, Masaya ^d   Yoshida, Kiyotsugu ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Drosha; Microarray; Mirna processing

Indexed keywords

AMPHIREGULIN; DEAD BOX PROTEIN; MICRORNA; PROTEIN BCL 2; PROTEIN DDX5; PROTEIN DROSHA; PROTEIN P53; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIOGENESIS; CONTROLLED STUDY; DNA DAMAGE; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA PROCESSING; TRANSCRIPTION REGULATION;

DROSHA; MICROARRAY; MIRNA PROCESSING;

APOPTOSIS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DEAD-BOX RNA HELICASES; DNA DAMAGE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN SITU NICK-END LABELING; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MASS SPECTROMETRY; MICROARRAY ANALYSIS; MICRORNAS; PHOSPHORYLATION; REAL-TIME POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84892599654     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1313675111     Document Type: Article

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