DYRK2 controls the epithelial-mesenchymal transition in breast cancer by degrading Snail

Cancer Letters

Volumn 339, Issue 2, 2013, Pages 214-225

  Mimoto, Rei ^a   Taira, Naoe ^a,b   Takahashi, Hiroyuki ^a   Yamaguchi, Tomoko ^a   Okabe, Masataka ^a   Uchida, Ken ^a   Miki, Yoshio ^b   Yoshida, Kiyotsugu ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Breast cancer; DYRK2; E cadherin; EMT; Snail

Indexed keywords

DYRK2 PROTEIN; PHOSPHOTRANSFERASE; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER PROGNOSIS; CONTROLLED STUDY; DOWN REGULATION; DYRK2 GENE; EMBRYO; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN STABILITY; REGULATORY MECHANISM; TUMOR INVASION;

BREAST CANCER; DYRK2; E-CADHERIN; EMT; SNAIL;

BREAST NEOPLASMS; CADHERINS; CELL LINE, TUMOR; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION; GENE SILENCING; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PHOSPHORYLATION; PROGNOSIS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STABILITY; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTEOLYSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UBIQUITIN;

GASTROPODA;

EID: 84883795806     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.06.005     Document Type: Article

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