Vaccine activation of the nutrient sensor GCN2 in dendritic cells enhances antigen presentation

Science

Volumn 343, Issue 6168, 2014, Pages 313-317

  Ravindran, Rajesh ^a   Khan, Nooruddin ^a,b   Nakaya, Helder I ^a,c   Li, Shuzhao ^a   Loebbermann, Jens ^a   Maddur, Mohan S ^a   Park, Youngja ^d   Jones, Dean P ^c   Chappert, Pascal ^e,f   Davoust, Jean ^e,f   Weiss, David S ^c   Virgin, Herbert W ^g   Ron, David ^h   Pulendran, Bali ^a,c  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY OF HYDERABAD   (India)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Korea University   (South Korea)

^e INSERM   (France)

^f UNIVERSITÉ PARIS DESCARTES   (France)

^g WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; GAMMA INTERFERON; GENERAL CONTROL NONDEREPRESSIBLE 2 KINASE; INITIATION FACTOR 2ALPHA; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; PEPTIDES AND PROTEINS; PHOSPHOTRANSFERASE; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; YELLOW FEVER VACCINE;

ANTIGEN; BLOOD; CYTOLOGY; IMMUNITY; SENSOR; VACCINE; VIRUS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ARTICLE; AUTOPHAGY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; VACCINATION;

EID: 84892598603     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1246829     Document Type: Article

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