The interferon-induced double-stranded RNA-activated protein kinase PKR will phosphorylate serine, threonine, or tyrosine at residue 51 in eukaryotic initiation factor 2α

Journal of Biological Chemistry

Volumn 274, Issue 45, 1999, Pages 32198-32203

  Lu, Jingfang ^a   O'Hara, Eileen B ^a   Trieselmann, Bruce A ^a   Romano, Patrick R ^a   Dever, Thomas E ^a,b  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; INITIATION FACTOR 2; INTERFERON; PROTEIN KINASE; SERINE; THREONINE; TYROSINE;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; ENZYME SPECIFICITY; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RNA TRANSLATION; TRANSLATION REGULATION;

ALLELES; CELL LINE; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2; HUMANS; ISOELECTRIC FOCUSING; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; SERINE; SUBSTRATE SPECIFICITY; THREONINE; TYROSINE;

EID: 0033527640     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.45.32198     Document Type: Article

References (37)

1. Clemens, M. J. (1996) in Translational Control (Hershey, J. W. B., Mathews, M. B., and Sonenberg, N., eds) pp. 139-172, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
2. Hinnebusch, A. G. (1994) Semin. Cell Biol. 5, 417-426
3. Santoyo, J., Alcalde, J., Mendez, R., Pulido, D., and de Haro, C. (1997) J. Biol. Chem. 272, 12544-12550
4. Olsen, D. S., Jordan, B., Chen, D., Wek, R. C., and Cavener, D. R. (1998) Genetics 149, 1495-1509
5. Harding, H. P., Zhang, Y., and Ron, D. (1999) Nature 397, 271-274
6. Shi, Y., Vattem, K. M., Sood, R., An, J., Liang, J., Stramm, L., and Wek, R. C. (1998) Mol. Cell. Biol. 18, 7499-7509
7. Dever, T. E., Chen, J. J., Barber, G. N., Cigan, A. M., Feng, L., Donahue, T. F., London, I. M., Katze, M. G., and Hinnebusch, A. G. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 4616-4620
8. Chong, K. L., Feng, L., Schappert, K., Meurs, E., Donahue, T. F., Friesen, J. D., Hovanessian, A. G., and Williams, B. R. G. (1992) EMBO J. 11, 1553-1562
9. Ramirez, M., Wek, R. C., Vazquez de Aldana, C. R., Jackson, B. M., Freeman, B., and Hinnebusch, A. G. (1992) Mol. Cell. Biol. 12, 5801-5815
10. Romano, P. R., Green, S. R., Barber, G. N., Mathews, M. B., and Hinnebusch, A. G. (1995) Mol. Cell. Biol. 15, 365-378
11. Yang, Y.-L., Reis, L. F. L., Pavlovic, J., Aguzzi, A., Schafer, R., Kumar, A., Williams, B. R. G., Aguet, M., and Weissmann, C. (1995) EMBO J. 14, 6095-6106
12. Koromilas, A. E., Roy, S., Barber, G. N., Katze, M. G., and Sonenberg, N. (1992) Science 287, 1685-1689
13. Kumar, A., Haque, J., Lacoste, J., Hiscott, J., and Williams, B. R. G. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 6288-6292
14. McMillan, N. A. J., Chun, R. F., Siderovski, D. P., Galabru, J., Toone, W. M., Samuel, C. E., Mak, T. W., Hovanessian, A. G., Jeang, K., and Williams, B. R. G. (1995) Virology 213, 413-424
15. Brand, S., Kobayashi, R., and Mathews, M. (1997) J. Biol. Chem. 272, 8388-8395
16. Langland, J., Kao, P., and Jacobs, B. (1999) Biochemistry 38, 6361-6368
17. Mellor, H., and Proud, C. G. (1991) Biochem. Biophys. Res. Commun. 178, 430-437
18. Weinmaster, G., and Pawson, T. (1986) J. Biol. Chem. 261, 328-333
19. Hubbard, S. R., Wei, L., Ellis, L., and Hendrickson, W. A. (1994) Nature 372, 746-754
20. Taylor, S. S., Radzio-Andzelm, E., and Hunter, T. (1995) FASEB J. 9, 1255-1266
21. Christianson, T. W., Sikorski, R. S., Dante, M., Shero, J. H., and Hieter, P. (1992) Gene (Amst.) 110, 119-122
22. Dever, T. E., Feng, L., Wek, R. C., Cigan, A. M., Donahue, T. D., and Hinnebusch, A. G. (1992) Cell 68, 585-596
23. Rose, M. D., Winston, F., and Hieter, P. (1989) Methods in Yeast Genetics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
24. Barber, G. N., Tomita, J., Hovanessian, A. G., Meurs, E., and Katze, M. G. (1991) Biochemistry 30, 10356-10361
25. Icely, P. L., Gros, P., Bergeron, J. J. M., Devault, A., Afar, D. E. H., and Bell, J. C. (1991) J. Biol. Chem. 286, 16073-16077
26. Abraham, N., Jaramillo, M., Duncan, P., Methot, N., Icely, P., Stojdl, D., Barber, G., and Bell, J. (1998) Exp. Cell Res. 244, 394-404
27. Lindberg, R. A., Quinn, A. M., and Hunter, T. (1992) Trends Biochem. Sci. 17, 114-119
28. Lindberg, R. A., Fischer, W. H., and Hunter, T. (1993) Oncogene 8, 351-359
29. Kawagishi-Kobayashi, M., Silverman, J. B., Ung, T. L., and Dever, T. E. (1997) Mol. Cell. Biol. 17, 4146-4158
30. Mellor, H., and Proud, C. G. (1991) Biochem. Biophys. Res. Commun. 178, 430-437
31. Douville, E., Duncan, P., Abraham, N., and Bell, J. C. (1994) Cancer Metatasis Rev. 13, 1-7
32. Crews, C. M., Alessandrini, A., and Erikson, R. L. (1992) Science 258, 478-480
33. Mueller, P. R., Coleman, T. R., Kumagai, A., and Dunphy, W. G. (1995) Science 270, 86-90
34. Liu, F., Stanton, J. J., Wu, Z., and Piwnica-Worms, H. (1997) Mol. Cell. Biol. 17, 571-583
35. Der, S. D., and Lau, A. S. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8841-8845
36. Koromilas, A. E., Cantin, C., Craig, A. W. B., Jagus, R., Hiscott, J., and Sonenberg, N. (1995) J. Biol. Chem. 270, 25426-25434
37. Abraham, N., Stojdl, D. F., Duncan, P. I., Methot, N., Ishii, T., Dube, M., Vanderhyden, B. C., Atkins, H. L., Gray, D. A., McBurney, M. W., Koromilas, A. E., Brown, E. G., Sonenberg, N., and Bell, J. C. (1999) J. Biol. Chem. 274, 5953-5962