Cytochrome P450 2A13 mediates the neoplastic transformation of human bronchial epithelial cells at a low concentration of aflatoxin B1

International Journal of Cancer

Volumn 134, Issue 7, 2014, Pages 1539-1548

  Zhang, Zhan ^a,b   Lu, Huiyuan ^a,c   Huan, Fei ^a   Meghan, Cromie ^d   Yang, Xuejiao ^a,b   Wang, Yun ^a,b   Wang, Xichen ^a,b   Wang, Xinru ^a,b   Wang, Shou Lin ^a,b  

^a Nanjing Medical University   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c Fiangsu Entry Exit Inspection and Quarantine Bureau   (China)

^d TEXAS TECH UNIVERSITY   (United States)

Author keywords

aflatoxin B1; ataxia telangiectasia and Rad3 related pathway; BEAS 2B cells; cytochrome P450 2A13; neoplastic transformation

Indexed keywords

AFLATOXIN B1; ATR PROTEIN; BRCA1 PROTEIN; CASPASE 3; CYTOCHROME P450 1A2; CYTOCHROME P450 2A; CYTOCHROME P450 2A13; CYTOCHROME P450 2A6; DNA; MRE11 PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; RAD50 PROTEIN; RAD51 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRONCHUS MUCOSA; CELL SURVIVAL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; LUNG CARCINOGENESIS; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS; UPREGULATION;

AFLATOXIN B1; ATAXIA TELANGIECTASIA AND RAD3-RELATED PATHWAY; BEAS-2B CELLS; CYTOCHROME P450 2A13; NEOPLASTIC TRANSFORMATION;

AFLATOXIN B1; ANIMALS; APOPTOSIS; ARYL HYDROCARBON HYDROXYLASES; ATAXIA TELANGIECTASIA MUTATED PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BRONCHI; CASPASE 3; CELL LINE; CELL MOVEMENT; CELL TRANSFORMATION, NEOPLASTIC; CYTOCHROME P-450 ENZYME SYSTEM; DNA ADDUCTS; DNA REPAIR; EPITHELIAL CELLS; HUMANS; MICE; MICE, NUDE; POLY(ADP-RIBOSE) POLYMERASES; UP-REGULATION;

EID: 84892592798     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28489     Document Type: Article

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