Hydrophobic plug functions as a gate in voltage-gated proton channels

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 2, 2014, Pages

  Chamberlin, Adam ^a   Qiu, Feng ^b   Rebolledo, Santiago ^b   Wang, Yibo ^a   Noskov, Sergei Y ^a   Larsson, H Peter ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Blocker; Molecular dynamics; Mutagenesis cycle; Voltage gating; VSOP

Indexed keywords

ION CHANNEL; UNCLASSIFIED DRUG; VOLTAGE GATED PROTON CHANNEL; WATER;

ARTICLE; CHANNEL GATING; CONFORMATIONAL TRANSITION; FLUORESCENCE; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR INTERACTION; MOLECULAR MODEL; MUTAGENESIS; MUTANT; PERMEABILITY; PRIORITY JOURNAL; PROTON TRANSPORT; SENSOR; THERMODYNAMICS;

BLOCKER; MOLECULAR DYNAMICS; MUTAGENESIS CYCLE; VOLTAGE GATING; VSOP;

BASE SEQUENCE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ION CHANNEL GATING; ION CHANNELS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ANALYSIS, DNA; THERMODYNAMICS;

EID: 84892574563     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1318018111     Document Type: Article

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