Structural basis for the neutralization and specificity of Staphylococcal enterotoxin B against its MHC Class II binding site

mAbs

Volumn 6, Issue 1, 2014, Pages 119-129

  Xia, Tian ^a,e   Liang, Shuaiyi ^b   Wang, Huajing ^a,c   Hu, Shi ^a,c   Sun, Yuna ^d   Yu, Xiaojie ^a,c   Han, Jun ^e   Li, Jun ^e   Guo, Shangjing ^e   Dai, Jianxin ^a,c,e   Lou, Zhiyong ^b   Guo, Yajun ^a,c,e  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b TSINGHUA UNIVERSITY   (China)

^c State Key Lab Antibody Med and Targeting Therapy   (China)

^d INSTITUTE OF BIOPHYSICS   (China)

^e LIAOCHENG UNIVERSITY   (China)

Author keywords

Crystal structure; Enterotoxin B; Mechanism; Neutralizing antibody; Staphylococcus aureus

Indexed keywords

EPITOPE; GLUTAMINE; LYSINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; STAPHYLOCOCCUS ENTEROTOXIN B; TYROSINE;

ANIMAL EXPERIMENT; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTALLIZATION; CRYSTALLOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; MUTAGENESIS; NONHUMAN; STAPHYLOCOCCUS AUREUS; TOXIN STRUCTURE;

CRYSTAL STRUCTURE; ENTEROTOXIN B; MECHANISM; NEUTRALIZING ANTIBODY; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; ANTIBODIES, NEUTRALIZING; BACTERIAL PROTEINS; BINDING SITES; ENTEROTOXINS; HISTOCOMPATIBILITY ANTIGENS CLASS II; MICE; MICE, INBRED BALB C; MUTAGENESIS, SITE-DIRECTED; SHOCK, SEPTIC;

EID: 84892565858     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.27106     Document Type: Article

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