-
1
-
-
58149471229
-
Down-regulation of Akt/mammalian target of rapamycin signaling pathway in response to myostatin overexpression in skeletal muscle
-
doi:10.1210/en.2008-0959
-
Amirouche A, Durieux AC, Banzet S, Koulmann N, Bonnefoy R, Mouret C, Bigard X, Peinnequin A, Freyssenet D (2009) Down-regulation of Akt/mammalian target of rapamycin signaling pathway in response to myostatin overexpression in skeletal muscle. Endocrinology 150(1):286-294. doi:10.1210/en.2008-0959
-
(2009)
Endocrinology
, vol.150
, Issue.1
, pp. 286-294
-
-
Amirouche, A.1
Durieux, A.C.2
Banzet, S.3
Koulmann, N.4
Bonnefoy, R.5
Mouret, C.6
Bigard, X.7
Peinnequin, A.8
Freyssenet, D.9
-
2
-
-
0037358776
-
Myostatin expression in age and denervation-induced skeletal muscle atrophy
-
Baumann AP, Ibebunjo C, Grasser WA, Paralkar VM (2003) Myostatin expression in age and denervation-induced skeletal muscle atrophy. J Musculoskelet Neuronal Interact 3(1):8-16
-
(2003)
J Musculoskelet Neuronal Interact
, vol.3
, Issue.1
, pp. 8-16
-
-
Baumann, A.P.1
Ibebunjo, C.2
Grasser, W.A.3
Paralkar, V.M.4
-
3
-
-
73949143033
-
Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia
-
doi:10.1016/j.bbrc.2009.12.123
-
Benny Klimek ME, Aydogdu T, Link MJ, Pons M, Koniaris LG, Zimmers TA (2010) Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia. Biochem Biophys Res Commun 391 (3):1548-1554. doi:10.1016/j.bbrc.2009.12.123
-
(2010)
Biochem Biophys Res Commun
, vol.391
, Issue.3
, pp. 1548-1554
-
-
Benny Klimek, M.E.1
Aydogdu, T.2
Link, M.J.3
Pons, M.4
Koniaris, L.G.5
Zimmers, T.A.6
-
4
-
-
79953231709
-
A Longer and Healthier Life with TOR down-regulation: Genetics and drugs
-
doi:10.1042/BST0390460
-
Bjedov I, Partridge L (2011) A longer and healthier life with TOR down-regulation: genetics and drugs. Biochem Soc Trans 39(2):460-465. doi:10.1042/BST0390460
-
(2011)
Biochem Soc Trans
, vol.39
, Issue.2
, pp. 460-465
-
-
Bjedov, I.1
Partridge, L.2
-
5
-
-
0037191752
-
Functional improvement of dystrophic muscle by myostatin blockade
-
doi:10.1038/nature01154
-
Bogdanovich S, Krag TO, Barton ER, Morris LD, Whittemore LA, Ahima RS, Khurana TS (2002) Functional improvement of dystrophic muscle by myostatin blockade. Nature 420(6914):418-421. doi:10.1038/nature01154
-
(2002)
Nature
, vol.420
, Issue.6914
, pp. 418-421
-
-
Bogdanovich, S.1
Krag, T.O.2
Barton, E.R.3
Morris, L.D.4
Whittemore, L.A.5
Ahima, R.S.6
Khurana, T.S.7
-
6
-
-
0032832616
-
Skeletal muscle myostatin mRNA expression is fiber-type specific and increases during hindlimb unloading
-
Carlson CJ, Booth FW, Gordon SE (1999) Skeletal muscle myostatin mRNA expression is fiber-type specific and increases during hindlimb unloading. Am J Physiol 277(2 Pt 2):R601-606
-
(1999)
Am J Physiol
, vol.277
, Issue.2 PART 2
-
-
Carlson, C.J.1
Booth, F.W.2
Gordon, S.E.3
-
7
-
-
34249997024
-
Replicating genotype-phenotype associations
-
doi:10.1038/447655a
-
Chanock SJ, Manolio T, Boehnke M, Boerwinkle E, Hunter DJ, Thomas G, Hirschhorn JN, Abecasis G, Altshuler D, Bailey-Wilson JE, Brooks LD, Cardon LR, Daly M, Donnelly P, Fraumeni JF Jr, Freimer NB, Gerhard DS, Gunter C, Guttmacher AE, Guyer MS, Harris EL, Hoh J, Hoover R, Kong CA, Merikangas KR, Morton CC, Palmer LJ, Phimister EG, Rice JP, Roberts J, Rotimi C, Tucker MA, Vogan KJ, Wacholder S, Wijsman EM, Winn DM, Collins FS (2007) Replicating genotype-phenotype associations. Nature 447(7145):655-660. doi:10.1038/447655a
-
(2007)
Nature
, vol.447
, Issue.7145
, pp. 655-660
-
-
Chanock, S.J.1
Manolio, T.2
Boehnke, M.3
Boerwinkle, E.4
Hunter, D.J.5
Thomas, G.6
Hirschhorn, J.N.7
Abecasis, G.8
Altshuler, D.9
Bailey-Wilson, J.E.10
Brooks, L.D.11
Cardon, L.R.12
Daly, M.13
Donnelly, P.14
Fraumeni Jr., J.F.15
Freimer, N.B.16
Gerhard, D.S.17
Gunter, C.18
Guttmacher, A.E.19
Guyer, M.S.20
Harris, E.L.21
Hoh, J.22
Hoover, R.23
Kong, C.A.24
Merikangas, K.R.25
Morton, C.C.26
Palmer, L.J.27
Phimister, E.G.28
Rice, J.P.29
Roberts, J.30
Rotimi, C.31
Tucker, M.A.32
Vogan, K.J.33
Wacholder, S.34
Wijsman, E.M.35
Winn, D.M.36
Collins, F.S.37
more..
-
8
-
-
51649086109
-
Exceptional longevity does not result in excessive levels of disability
-
doi:10.1073/pnas.0804931105
-
Christensen K, McGue M, Petersen I, Jeune B, Vaupel JW (2008) Exceptional longevity does not result in excessive levels of disability. Proc Natl Acad Sci U S A 105 (36):13274-13279. doi:10.1073/pnas.0804931105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.36
, pp. 13274-13279
-
-
Christensen, K.1
McGue, M.2
Petersen, I.3
Jeune, B.4
Vaupel, J.W.5
-
9
-
-
0023950998
-
The Barthel ADL Index: A reliability study
-
Collin C, Wade DT, Davies S, Horne V (1988) The Barthel ADL Index: a reliability study. Int Disabil Stud 10(2):61-63
-
(1988)
Int Disabil Stud
, vol.10
, Issue.2
, pp. 61-63
-
-
Collin, C.1
Wade, D.T.2
Davies, S.3
Horne, V.4
-
10
-
-
79960831814
-
Novel events in the molecular regulation of muscle mass in critically ill patients
-
doi:10.1113/jphysiol.2011.206193
-
Constantin D, McCullough J, Mahajan RP, Greenhaff PL (2011) Novel events in the molecular regulation of muscle mass in critically ill patients. J Physiol 589(Pt 15):3883-3895. doi:10.1113/jphysiol.2011.206193
-
(2011)
J Physiol
, vol.589
, Issue.PART 15
, pp. 3883-3895
-
-
Constantin, D.1
McCullough, J.2
Mahajan, R.P.3
Greenhaff, P.L.4
-
11
-
-
0036677193
-
Myostatin polymorphisms and age-related sarcopenia in the Italian population
-
Corsi AM, Ferrucci L, Gozzini A, Tanini A, Brandi ML (2002) Myostatin polymorphisms and age-related sarcopenia in the Italian population. J Am Geriatr Soc 50(8):1463
-
(2002)
J Am Geriatr Soc
, vol.50
, Issue.8
, pp. 1463
-
-
Corsi, A.M.1
Ferrucci, L.2
Gozzini, A.3
Tanini, A.4
Brandi, M.L.5
-
12
-
-
70449900928
-
TOR complex 2: A signaling pathway of its own
-
doi:10.1016/j.tibs.2009.09.004
-
Cybulski N, Hall MN (2009) TOR complex 2: a signaling pathway of its own. Trends Biochem Sci 34(12):620-627.doi:10.1016/j.tibs.2009.09.004
-
(2009)
Trends Biochem Sci
, vol.34
, Issue.12
, pp. 620-627
-
-
Cybulski, N.1
Hall, M.N.2
-
13
-
-
9244254305
-
Skeletal muscle atrophy is associated with an increased expression of myostatin and impaired satellite cell function in the portacaval anastamosis rat
-
doi:10.1152/ajpgi.00202.2004
-
Dasarathy S, Dodig M, Muc SM, Kalhan SC, McCullough AJ (2004) Skeletal muscle atrophy is associated with an increased expression of myostatin and impaired satellite cell function in the portacaval anastamosis rat. Am J Physiol Gastrointest Liver Physiol 287(6):G1124-1130.doi:10.1152/ajpgi.00202.2004
-
(2004)
Am J Physiol Gastrointest Liver Physiol
, vol.287
, Issue.6
-
-
Dasarathy, S.1
Dodig, M.2
Muc, S.M.3
Kalhan, S.C.4
McCullough, A.J.5
-
14
-
-
77949505932
-
Preliminary evidence of a genetic association between chromosome 9p21.3 and human longevity
-
doi:10.1089/rej.2009.0970
-
Emanuele E, Fontana JM, Minoretti P, Geroldi D (2010) Preliminary evidence of a genetic association between chromosome 9p21.3 and human longevity. Rejuvenation research 13(1):23-26. doi:10.1089/rej.2009.0970
-
(2010)
Rejuvenation Research
, vol.13
, Issue.1
, pp. 23-26
-
-
Emanuele, E.1
Fontana, J.M.2
Minoretti, P.3
Geroldi, D.4
-
15
-
-
78650239404
-
Functions and regulation of the 70 kDa ribosomal S6 kinases
-
doi:10.1016/j.biocel.2010.09.018
-
Fenton TR, Gout IT (2011) Functions and regulation of the 70 kDa ribosomal S6 kinases. Int J Biochem Cell Biol 43 (1):47-59. doi:10.1016/j. biocel.2010.09.018
-
(2011)
Int J Biochem Cell Biol
, vol.43
, Issue.1
, pp. 47-59
-
-
Fenton, T.R.1
Gout, I.T.2
-
16
-
-
0033387710
-
Frequent sequence variation in the human myostatin (GDF8) gene as a marker for analysis of muscle-related phenotypes
-
doi:10.1006/geno.1999.5984
-
Ferrell RE, Conte V, Lawrence EC, Roth SM, Hagberg JM,Hurley BF (1999) Frequent sequence variation in the human myostatin (GDF8) gene as a marker for analysis of muscle-related phenotypes. Genomics 62(2):203-207.doi:10.1006/geno. 1999.5984
-
(1999)
Genomics
, vol.62
, Issue.2
, pp. 203-207
-
-
Ferrell, R.E.1
Conte, V.2
Lawrence, E.C.3
Roth, S.M.4
Hagberg, J.M.5
Hurley, B.F.6
-
17
-
-
0016823810
-
Mini-mental state. A practical method for grading the cognitive state of patients for the clinician
-
Folstein MF, Folstein SE, McHugh PR (1975) Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12(3):189-198
-
(1975)
J Psychiatr Res
, vol.12
, Issue.3
, pp. 189-198
-
-
Folstein, M.F.1
Folstein, S.E.2
McHugh, P.R.3
-
18
-
-
77951176737
-
Extending healthy life span - From yeast to humans
-
doi:10.1126/science.1172539
-
Fontana L, Partridge L, Longo VD (2010) Extending healthy life span - from yeast to humans. Science 328(5976):321-326. doi:10.1126/science.1172539
-
(2010)
Science
, vol.328
, Issue.5976
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
19
-
-
84872618679
-
Genes and the ageing muscle: A review on genetic association studies
-
doi:10.1007/s11357-011-9327-0
-
Garatachea N, Lucía A (2013) Genes and the ageing muscle: a review on genetic association studies. Age (Dordr) 35 (1):207-233. doi:10.1007/s11357-011-9327-0
-
(2013)
Age (Dordr)
, vol.35
, Issue.1
, pp. 207-233
-
-
Garatachea, N.1
Lucía, A.2
-
20
-
-
13044265837
-
Organization of the human myostatin gene and expression in healthy men and HIVinfected men with muscle wasting
-
Gonzalez-Cadavid NF, Taylor WE, Yarasheski K, Sinha-Hikim I, Ma K, Ezzat S, Shen R, Lalani R, Asa S, Mamita M, Nair G, Arver S, Bhasin S (1998) Organization of the human myostatin gene and expression in healthy men and HIVinfected men with muscle wasting. Proc Natl Acad Sci U S A 95(25):14938-14943
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.25
, pp. 14938-14943
-
-
Gonzalez-Cadavid, N.F.1
Taylor, W.E.2
Yarasheski, K.3
Sinha-Hikim, I.4
Ma, K.5
Ezzat, S.6
Shen, R.7
Lalani, R.8
Asa, S.9
Mamita, M.10
Nair, G.11
Arver, S.12
Bhasin, S.13
-
21
-
-
77956186674
-
The K153R variant in the myostatin gene and sarcopenia at the end of the human lifespan
-
doi:10.1007/s11357-010-9139-7
-
Gonzalez-Freire M, Rodriguez-Romo G, Santiago C,Bustamante-Ara N, Yvert T, Gomez-Gallego F, Serra Rexach JA, Ruiz JR, Lucia A (2010) The K153R variant in the myostatin gene and sarcopenia at the end of the human lifespan. Age 32(3):405-409. doi:10.1007/s11357-010-9139-7
-
(2010)
Age
, vol.32
, Issue.3
, pp. 405-409
-
-
Gonzalez-Freire, M.1
Rodriguez-Romo, G.2
Santiago, C.3
Bustamante-Ara, N.4
Yvert, T.5
Gomez-Gallego, F.6
Serra Rexach, J.A.7
Ruiz, J.R.8
Lucia, A.9
-
22
-
-
16944364045
-
A deletion in the bovine myostatin gene causes the doublemuscled phenotype in cattle
-
doi:10.1038/ng0997-71
-
Grobet L, Martin LJ, Poncelet D, Pirottin D, Brouwers B, Riquet J, Schoeberlein A, Dunner S, Menissier F, Massabanda J, Fries R, Hanset R, Georges M (1997) A deletion in the bovine myostatin gene causes the doublemuscled phenotype in cattle. Nat Genet 17(1):71-74.doi:10.1038/ng0997-71
-
(1997)
Nat Genet
, vol.17
, Issue.1
, pp. 71-74
-
-
Grobet, L.1
Martin, L.J.2
Poncelet, D.3
Pirottin, D.4
Brouwers, B.5
Riquet, J.6
Schoeberlein, A.7
Dunner, S.8
Menissier, F.9
Massabanda, J.10
Fries, R.11
Hanset, R.12
Georges, M.13
-
23
-
-
3042728655
-
Linkage of myostatin pathway genes with knee strength in humans
-
doi:10.1152/physiolgenomics.00224.2003
-
Huygens W, Thomis MA, Peeters MW, Aerssens J, Janssen R, Vlietinck RF, Beunen G (2004) Linkage of myostatin pathway genes with knee strength in humans. Physiol Genom 17(3):264-270. doi:10.1152/physiolgenomics.00224.2003
-
(2004)
Physiol Genom
, vol.17
, Issue.3
, pp. 264-270
-
-
Huygens, W.1
Thomis, M.A.2
Peeters, M.W.3
Aerssens, J.4
Janssen, R.5
Vlietinck, R.F.6
Beunen, G.7
-
24
-
-
1242317812
-
Characterization and identification of the inhibitory domain of GDF-8 propeptide
-
doi:10.1016/j.bbrc.2004.01.085
-
Jiang MS, Liang LF,Wang S, Ratovitski T, Holmstrom J, Barker C, Stotish R (2004) Characterization and identification of the inhibitory domain of GDF-8 propeptide. Biochem Biophys Res Commun 315(3):525-531. doi:10.1016/j.bbrc.2004. 01.085
-
(2004)
Biochem Biophys Res Commun
, vol.315
, Issue.3
, pp. 525-531
-
-
Jiang, M.S.1
Liang, L.F.2
Wang, S.3
Ratovitski, T.4
Holmstrom, J.5
Barker, C.6
Stotish, R.7
-
25
-
-
0035746806
-
Content and localization of myostatin in mouse skeletal muscles during aging, mechanical unloading and reloading
-
Kawada S, Tachi C, Ishii N (2001) Content and localization of myostatin in mouse skeletal muscles during aging, mechanical unloading and reloading. J Muscle Res Cell Motil 22(8):627-633
-
(2001)
J Muscle Res Cell Motil
, vol.22
, Issue.8
, pp. 627-633
-
-
Kawada, S.1
Tachi, C.2
Ishii, N.3
-
26
-
-
77950200010
-
The genetics of ageing
-
doi:10.1038/nature08980
-
Kenyon CJ (2010) The genetics of ageing. Nature 464 (7288):504-512. doi:10.1038/nature08980
-
(2010)
Nature
, vol.464
, Issue.7288
, pp. 504-512
-
-
Kenyon, C.J.1
-
27
-
-
67650093999
-
Myostatin and follistatin polymorphisms interact with muscle phenotypes and ethnicity
-
doi:10.1249/MSS.0b013e3181930337
-
Kostek MA, Angelopoulos TJ, Clarkson PM, Gordon PM, Moyna NM, Visich PS, Zoeller RF, Price TB, Seip RL, Thompson PD, Devaney JM, Gordish-Dressman H, Hoffman EP, Pescatello LS (2009) Myostatin and follistatin polymorphisms interact with muscle phenotypes and ethnicity. Med Sci Sports Exerc 41(5):1063-1071.doi:10.1249/MSS.0b013e3181930337
-
(2009)
Med Sci Sports Exerc
, vol.41
, Issue.5
, pp. 1063-1071
-
-
Kostek, M.A.1
Angelopoulos, T.J.2
Clarkson, P.M.3
Gordon, P.M.4
Moyna, N.M.5
Visich, P.S.6
Zoeller, R.F.7
Price, T.B.8
Seip, R.L.9
Thompson, P.D.10
Devaney, J.M.11
Gordish-Dressman, H.12
Hoffman, E.P.13
Pescatello, L.S.14
-
28
-
-
60549106515
-
Single muscle fiber contractile properties in adults with muscular dystrophy treated with MYO-029
-
doi:10.1002/mus.21200
-
Krivickas LS, Walsh R, Amato AA (2009) Single muscle fiber contractile properties in adults with muscular dystrophy treated with MYO-029. Muscle Nerve 39(1):3-9. doi:10.1002/mus.21200
-
(2009)
Muscle Nerve
, vol.39
, Issue.1
, pp. 3-9
-
-
Krivickas, L.S.1
Walsh, R.2
Amato, A.A.3
-
29
-
-
0037147210
-
Myostatin inhibits myoblast differentiation by down-regulating MyoD expression
-
doi:10.1074/jbc.M204291200
-
Langley B, Thomas M, Bishop A, Sharma M, Gilmour S, Kambadur R (2002) Myostatin inhibits myoblast differentiation by down-regulating MyoD expression. J Biol Chem277(51):49831-49840. doi:10.1074/jbc.M204291200
-
(2002)
J Biol Chem
, vol.277
, Issue.51
, pp. 49831-49840
-
-
Langley, B.1
Thomas, M.2
Bishop, A.3
Sharma, M.4
Gilmour, S.5
Kambadur, R.6
-
30
-
-
79951842509
-
Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice
-
doi:10.1016/j.ajpath.2010.10.035
-
Lawlor MW, Read BP, Edelstein R, Yang N, Pierson CR, Stein MJ, Wermer-Colan A, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH (2011) Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice. Am J Pathol 178(2):784-793. doi:10.1016/j.ajpath. 2010.10.035
-
(2011)
Am J Pathol
, vol.178
, Issue.2
, pp. 784-793
-
-
Lawlor, M.W.1
Read, B.P.2
Edelstein, R.3
Yang, N.4
Pierson, C.R.5
Stein, M.J.6
Wermer-Colan, A.7
Buj-Bello, A.8
Lachey, J.L.9
Seehra, J.S.10
Beggs, A.H.11
-
31
-
-
0035979253
-
Regulation of myostatin activity and muscle growth
-
doi:10.1073/pnas.151270098
-
Lee SJ, McPherron AC (2001) Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci U S A 98 (16):9306-9311. doi:10.1073/pnas.151270098
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.16
, pp. 9306-9311
-
-
Lee, S.J.1
McPherron, A.C.2
-
32
-
-
29144466479
-
Regulation of muscle growth by multiple ligands signaling through activin type 2 receptors
-
doi:10.1073/pnas.0505996102
-
Lee SJ, Reed LA, Davies MV, Girgenrath S, Goad ME, Tomkinson KN, Wright JF, Barker C, Ehrmantraut G, Holmstrom J, Trowell B, Gertz B, Jiang MS, Sebald SM, Matzuk M, Li E, Liang LF, Quattlebaum E, Stotish RL, Wolfman NM (2005) Regulation of muscle growth by multiple ligands signaling through activin type 2 receptors. Proc Natl Acad Sci U S A 102(50):18117-18122.doi:10.1073/pnas. 0505996102
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.50
, pp. 18117-18122
-
-
Lee, S.J.1
Reed, L.A.2
Davies, M.V.3
Girgenrath, S.4
Goad, M.E.5
Tomkinson, K.N.6
Wright, J.F.7
Barker, C.8
Ehrmantraut, G.9
Holmstrom, J.10
Trowell, B.11
Gertz, B.12
Jiang, M.S.13
Sebald, S.M.14
Matzuk, M.15
Li, E.16
Liang, L.F.17
Quattlebaum, E.18
Stotish, R.L.19
Wolfman, N.M.20
more..
-
33
-
-
77952957076
-
Mechanisms involved in the enhancement of mammalian target of rapamycin signalling and hypertrophy in skeletal muscle of myostatin-deficient mice
-
doi:10.1016/j.febslet.2010.04.039
-
Lipina C, Kendall H, McPherron AC, Taylor PM, Hundal HS (2010) Mechanisms involved in the enhancement of mammalian target of rapamycin signalling and hypertrophy in skeletal muscle of myostatin-deficient mice. FEBS Lett 584(11):2403-2408. doi:10.1016/j.febslet.2010.04.039
-
(2010)
FEBS Lett
, vol.584
, Issue.11
, pp. 2403-2408
-
-
Lipina, C.1
Kendall, H.2
McPherron, A.C.3
Taylor, P.M.4
Hundal, H.S.5
-
34
-
-
38549170471
-
Myostatin antisense RNA-mediated muscle growth in normal and cancer cachexia mice
-
doi:10.1038/sj.gt.3303016
-
Liu CM, Yang Z, Liu CW, Wang R, Tien P, Dale R, Sun LQ (2008) Myostatin antisense RNA-mediated muscle growth in normal and cancer cachexia mice. Gene Ther 15(3):155-160. doi:10.1038/sj.gt.3303016
-
(2008)
Gene Ther
, vol.15
, Issue.3
, pp. 155-160
-
-
Liu, C.M.1
Yang, Z.2
Liu, C.W.3
Wang, R.4
Tien, P.5
Dale, R.6
Sun, L.Q.7
-
35
-
-
70450195021
-
Functional evaluation: The barthel index
-
Mahoney FI, Barthel DW (1965) Functional Evaluation: the Barthel Index. Md State Med J 14:61-65
-
(1965)
Md State Med J
, vol.14
, pp. 61-65
-
-
Mahoney, F.I.1
Barthel, D.W.2
-
36
-
-
34547617380
-
Genetic determinants of human health span and life span: Progress and new opportunities
-
doi:10.1371/journal.pgen.0030125
-
Martin GM, Bergman A, Barzilai N (2007) Genetic determinants of human health span and life span: progress and new opportunities. PLoS Genet 3(7):e125. doi:10.1371/journal.pgen.0030125
-
(2007)
PLoS Genet
, vol.3
, Issue.7
-
-
Martin, G.M.1
Bergman, A.2
Barzilai, N.3
-
37
-
-
33749254273
-
Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF-kappaB-independent, FoxO1-dependent mechanism
-
doi:10.1002/jcp.20757
-
McFarlane C, Plummer E, Thomas M, Hennebry A, Ashby M, Ling N, Smith H, Sharma M, Kambadur R (2006) Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF-kappaB-independent, FoxO1-dependent mechanism. J Cell Physiol 209(2):501-514. doi:10.1002/jcp.20757
-
(2006)
J Cell Physiol
, vol.209
, Issue.2
, pp. 501-514
-
-
McFarlane, C.1
Plummer, E.2
Thomas, M.3
Hennebry, A.4
Ashby, M.5
Ling, N.6
Smith, H.7
Sharma, M.8
Kambadur, R.9
-
38
-
-
0030840359
-
Double muscling in cattle due to mutations in the myostatin gene
-
McPherron AC, Lee SJ (1997) Double muscling in cattle due to mutations in the myostatin gene. Proc Natl Acad Sci U S A 94(23):12457-12461
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, Issue.23
, pp. 12457-12461
-
-
McPherron, A.C.1
Lee, S.J.2
-
39
-
-
0031010050
-
Regulation of skeletal muscle mass in mice by a new TGF-beta superfamilymember
-
doi:10.1038/387083a0
-
McPherron AC, Lawler AM, Lee SJ (1997) Regulation of skeletal muscle mass in mice by a new TGF-beta superfamilymember. Nature 387(6628):83-90. doi:10.1038/387083a0
-
(1997)
Nature
, vol.387
, Issue.6628
, pp. 83-90
-
-
McPherron, A.C.1
Lawler, A.M.2
Lee, S.J.3
-
40
-
-
0942298558
-
Armcranking muscle power and arm isometric muscle strength are independent predictors of all-cause mortality in men
-
doi:10.1152/japplphysiol. 00370.2003
-
Metter EJ, Talbot LA, Schrager M, Conwit RA (2004) Armcranking muscle power and arm isometric muscle strength are independent predictors of all-cause mortality in men. J Appl Physiol 96(2):814-821. doi:10.1152/japplphysiol. 00370.2003
-
(2004)
J Appl Physiol
, vol.96
, Issue.2
, pp. 814-821
-
-
Metter, E.J.1
Talbot, L.A.2
Schrager, M.3
Conwit, R.A.4
-
41
-
-
28444494743
-
Effect of the functional toll-like receptor 4 Asp299Gly polymorphism on susceptibility to late-onset Alzheimer's disease
-
doi:10.1016/j.neulet.2005.08.047
-
Minoretti P, Gazzaruso C, Vito CD, Emanuele E, Bianchi M, Coen E, Reino M, Geroldi D (2006) Effect of the functional toll-like receptor 4 Asp299Gly polymorphism on susceptibility to late-onset Alzheimer's disease. Neurosci Lett 391(3):147-149. doi:10.1016/j.neulet.2005.08.047
-
(2006)
Neurosci Lett
, vol.391
, Issue.3
, pp. 147-149
-
-
Minoretti, P.1
Gazzaruso, C.2
Vito, C.D.3
Emanuele, E.4
Bianchi, M.5
Coen, E.6
Reino, M.7
Geroldi, D.8
-
42
-
-
73949131481
-
Effects of myostatin deletion in aging mice
-
doi:10.1111/j.1474-9726.2009.00508.x
-
Morissette MR, Stricker JC, Rosenberg MA, Buranasombati C, Levitan EB, Mittleman MA, Rosenzweig A (2009) Effects of myostatin deletion in aging mice. Aging cell 8(5):573-583. doi:10.1111/j.1474-9726.2009.00508.x
-
(2009)
Aging Cell
, vol.8
, Issue.5
, pp. 573-583
-
-
Morissette, M.R.1
Stricker, J.C.2
Rosenberg, M.A.3
Buranasombati, C.4
Levitan, E.B.5
Mittleman, M.A.6
Rosenzweig, A.7
-
43
-
-
67349251521
-
A soluble activin type 2B receptor improves function in a mouse model of amyotrophic lateral sclerosis
-
doi:10.1016/j.expneurol.2009.02.017
-
Morrison BM, Lachey JL, Warsing LC, Ting BL, Pullen AE, Underwood KW, Kumar R, Sako D, Grinberg A, Wong V, Colantuoni E, Seehra JS, Wagner KR (2009) A soluble activin type 2B receptor improves function in a mouse model of amyotrophic lateral sclerosis. Exp Neurol 217(2):258-268. doi:10.1016/j. expneurol.2009.02.017
-
(2009)
Exp Neurol
, vol.217
, Issue.2
, pp. 258-268
-
-
Morrison, B.M.1
Lachey, J.L.2
Warsing, L.C.3
Ting, B.L.4
Pullen, A.E.5
Underwood, K.W.6
Kumar, R.7
Sako, D.8
Grinberg, A.9
Wong, V.10
Colantuoni, E.11
Seehra, J.S.12
Wagner, K.R.13
-
44
-
-
34249733201
-
A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs
-
doi:10.1371/journal.pgen.0030079
-
Mosher DS, Quignon P, Bustamante CD, Sutter NB, Mellersh CS, Parker HG, Ostrander EA (2007) A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS genetics 3(5):e79. doi:10.1371/journal.pgen.0030079
-
(2007)
PLoS Genetics
, vol.3
, Issue.5
-
-
Mosher, D.S.1
Quignon, P.2
Bustamante, C.D.3
Sutter, N.B.4
Mellersh, C.S.5
Parker, H.G.6
Ostrander, E.A.7
-
45
-
-
77952070627
-
Antibody-directed myostatin inhibition improves diaphragm pathology in young but not adult dystrophic mdx mice
-
doi:10.2353/ajpath.2010.090932
-
Murphy KT, Ryall JG, Snell SM, Nair L, Koopman R, Krasney PA, Ibebunjo C, Holden KS, Loria PM, Salatto CT, Lynch GS (2010) Antibody-directed myostatin inhibition improves diaphragm pathology in young but not adult dystrophic mdx mice. Am J Pathol 176(5):2425-2434. doi:10.2353/ajpath.2010.090932
-
(2010)
Am J Pathol
, vol.176
, Issue.5
, pp. 2425-2434
-
-
Murphy, K.T.1
Ryall, J.G.2
Snell, S.M.3
Nair, L.4
Koopman, R.5
Krasney, P.A.6
Ibebunjo, C.7
Holden, K.S.8
Loria, P.M.9
Salatto, C.T.10
Lynch, G.S.11
-
46
-
-
77951227871
-
TOR-dependent control of autophagy: Biting the hand that feeds
-
doi:10.1016/j.ceb.2009.11.005
-
Neufeld TP (2010) TOR-dependent control of autophagy: biting the hand that feeds. Curr Opin Cell Biol 22(2):157-168.doi:10.1016/j.ceb.2009.11.005
-
(2010)
Curr Opin Cell Biol
, vol.22
, Issue.2
, pp. 157-168
-
-
Neufeld, T.P.1
-
47
-
-
58849124144
-
Hydrodynamic limb vein injection of adeno-associated virus serotype 8 vector carrying canine myostatin propeptide gene into normal dogs enhances muscle growth
-
doi:10.1089/hum.2008.135
-
Qiao C, Li J, Zheng H, Bogan J, Yuan Z, Zhang C, Bogan D, Kornegay J, Xiao X (2009) Hydrodynamic limb vein injection of adeno-associated virus serotype 8 vector carrying canine myostatin propeptide gene into normal dogs enhances muscle growth. Hum Gene Ther 20(1):1-10.doi:10.1089/hum.2008.135
-
(2009)
Hum Gene Ther
, vol.20
, Issue.1
, pp. 1-10
-
-
Qiao, C.1
Li, J.2
Zheng, H.3
Bogan, J.4
Yuan, Z.5
Zhang, C.6
Bogan, D.7
Kornegay, J.8
Xiao, X.9
-
48
-
-
78149475088
-
Regulation of mammalian autophagy in physiology and pathophysiology
-
doi:10.1152/physrev.00030.2009
-
Ravikumar B, Sarkar S, Davies JE, Futter M, Garcia-Arencibia M, Green-Thompson ZW, Jimenez-Sanchez M, Korolchuk VI, Lichtenberg M, Luo S, Massey DC, Menzies FM, Moreau K, Narayanan U, Renna M, Siddiqi FH, Underwood BR, Winslow AR, Rubinsztein DC (2010) Regulation of mammalian autophagy in physiology and pathophysiology. Physiol Rev 90(4):1383-1435.doi:10.1152/physrev. 00030.2009
-
(2010)
Physiol Rev
, vol.90
, Issue.4
, pp. 1383-1435
-
-
Ravikumar, B.1
Sarkar, S.2
Davies, J.E.3
Futter, M.4
Garcia-Arencibia, M.5
Green-Thompson, Z.W.6
Jimenez-Sanchez, M.7
Korolchuk, V.I.8
Lichtenberg, M.9
Luo, S.10
Massey, D.C.11
Menzies, F.M.12
Moreau, K.13
Narayanan, U.14
Renna, M.15
Siddiqi, F.H.16
Underwood, B.R.17
Winslow, A.R.18
Rubinsztein, D.C.19
-
49
-
-
2542422838
-
Differential response to exogenous and endogenous myostatin in myoblasts suggests that myostatin acts as an autocrine factor in vivo
-
doi:10.1210/en.2003-1166
-
Rios R, Fernandez-Nocelos S, Carneiro I, Arce VM, Devesa J (2004) Differential response to exogenous and endogenous myostatin in myoblasts suggests that myostatin acts as an autocrine factor in vivo. Endocrinology 145(6):2795-2803.doi:10.1210/en.2003-1166
-
(2004)
Endocrinology
, vol.145
, Issue.6
, pp. 2795-2803
-
-
Rios, R.1
Fernandez-Nocelos, S.2
Carneiro, I.3
Arce, V.M.4
Devesa, J.5
-
50
-
-
61849182695
-
Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy
-
doi:10.1093/hmg/ddn426
-
Rose FF Jr, Mattis VB, Rindt H, Lorson CL (2009) Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy. Hum Mol Genet 18 (6):997-1005. doi:10.1093/hmg/ddn426
-
(2009)
Hum Mol Genet
, vol.18
, Issue.6
, pp. 997-1005
-
-
Rose Jr., F.F.1
Mattis, V.B.2
Rindt, H.3
Lorson, C.L.4
-
51
-
-
47649097993
-
Association between muscular strength and mortality in men: Prospective cohort study
-
doi:10.1136/bmj.a439
-
Ruiz JR, Sui X, Lobelo F, Morrow JR Jr, Jackson AW, Sjostrom M, Blair SN (2008) Association between muscular strength and mortality in men: prospective cohort study. BMJ 337: a439. doi:10.1136/bmj.a439
-
(2008)
BMJ
, vol.337
-
-
Ruiz, J.R.1
Sui, X.2
Lobelo, F.3
Morrow Jr., J.R.4
Jackson, A.W.5
Sjostrom, M.6
Blair, S.N.7
-
52
-
-
84862279391
-
Sarcopenia and age-related endocrine function
-
doi:10.1155/2012/127362
-
Sakuma K, Yamaguchi A (2012) Sarcopenia and age-related endocrine function. Int J Endocrinol 2012:127362. doi:10.1155/2012/127362
-
(2012)
Int J Endocrinol
, vol.2012
, pp. 127362
-
-
Sakuma, K.1
Yamaguchi, A.2
-
53
-
-
66749167618
-
Smad2 and 3 transcription factors control muscle mass in adulthood
-
doi:10.1152/ajpcell.00104.2009
-
Sartori R, Milan G, Patron M, Mammucari C, Blaauw B, Abraham R, Sandri M (2009) Smad2 and 3 transcription factors control muscle mass in adulthood. Am J PhysiolCell Physiol 296(6):C1248-1257. doi:10.1152/ajpcell.00104.2009
-
(2009)
Am J PhysiolCell Physiol
, vol.296
, Issue.6
-
-
Sartori, R.1
Milan, G.2
Patron, M.3
Mammucari, C.4
Blaauw, B.5
Abraham, R.6
Sandri, M.7
-
54
-
-
33845198353
-
Human adaptive evolution at myostatin (GDF8), a regulator of muscle growth
-
doi:10.1086/509707
-
Saunders MA, Good JM, Lawrence EC, Ferrell RE, Li WH, Nachman MW (2006) Human adaptive evolution at myostatin (GDF8), a regulator of muscle growth. Am J Hum Genet 79(6):1089-1097. doi:10.1086/509707
-
(2006)
Am J Hum Genet
, vol.79
, Issue.6
, pp. 1089-1097
-
-
Saunders, M.A.1
Good, J.M.2
Lawrence, E.C.3
Ferrell, R.E.4
Li, W.H.5
Nachman, M.W.6
-
55
-
-
78649348967
-
Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
-
doi:10.1016/j.molcel.2010.09.026
-
Sengupta S, Peterson TR, Sabatini DM (2010) Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol Cell 40(2):310-322. doi:10.1016/j.molcel.2010.09.026
-
(2010)
Mol Cell
, vol.40
, Issue.2
, pp. 310-322
-
-
Sengupta, S.1
Peterson, T.R.2
Sabatini, D.M.3
-
56
-
-
33750527757
-
Prolonged absence of myostatin reduces sarcopenia
-
doi:10.1002/jcp.20778
-
Siriett V, Platt L, Salerno MS, Ling N, Kambadur R, Sharma M (2006) Prolonged absence of myostatin reduces sarcopenia. J Cell Physiol 209(3):866-873. doi:10.1002/jcp.20778
-
(2006)
J Cell Physiol
, vol.209
, Issue.3
, pp. 866-873
-
-
Siriett, V.1
Platt, L.2
Salerno, M.S.3
Ling, N.4
Kambadur, R.5
Sharma, M.6
-
57
-
-
77954235821
-
Targeting mTOR: Prospects for mTOR complex 2 inhibitors in cancer therapy
-
doi:10.1038/onc.2010.139
-
Sparks CA, Guertin DA (2010) Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy. Oncogene 29(26):3733-3744. doi:10.1038/onc.2010. 139
-
(2010)
Oncogene
, vol.29
, Issue.26
, pp. 3733-3744
-
-
Sparks, C.A.1
Guertin, D.A.2
-
58
-
-
80051986710
-
Meeting report: American aging association 40th annual meeting, raleigh, north carolina, june 3-6,2011
-
doi:10.1089/rej.2011.1216
-
Swan M (2011) Meeting report: American Aging Association 40th Annual Meeting, Raleigh, North Carolina, June 3-6,2011. Rejuvenation research 14(4):449-455. doi:10.1089/rej.2011.1216
-
(2011)
Rejuvenation Research
, vol.14
, Issue.4
, pp. 449-455
-
-
Swan, M.1
-
59
-
-
39549099293
-
Disentangling the roles of disability and morbidity in survival to exceptional old age
-
doi:10.1001/archinternmed.2007.75
-
Terry DF, Sebastiani P, Andersen SL, Perls TT (2008) Disentangling the roles of disability and morbidity in survival to exceptional old age. Arch Intern Med 168(3):277-283. doi:10.1001/archinternmed.2007.75
-
(2008)
Arch Intern Med
, vol.168
, Issue.3
, pp. 277-283
-
-
Terry, D.F.1
Sebastiani, P.2
Andersen, S.L.3
Perls, T.T.4
-
60
-
-
66749188280
-
Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size
-
doi:10.1152/ajpcell.00105.2009
-
Trendelenburg AU, Meyer A, Rohner D, Boyle J, Hatakeyama S, Glass DJ (2009) Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size. Am J Physiol Cell Physiol 296(6):C1258-1270. doi:10.1152/ajpcell.00105.2009
-
(2009)
Am J Physiol Cell Physiol
, vol.296
, Issue.6
-
-
Trendelenburg, A.U.1
Meyer, A.2
Rohner, D.3
Boyle, J.4
Hatakeyama, S.5
Glass, D.J.6
-
61
-
-
51649112491
-
Myostatin inhibition by a follistatin-derived peptide ameliorates the pathophysiology of muscular dystrophy model mice
-
Tsuchida K (2008) Myostatin inhibition by a follistatin-derived peptide ameliorates the pathophysiology of muscular dystrophy model mice. Acta Myol 27:14-18
-
(2008)
Acta Myol
, vol.27
, pp. 14-18
-
-
Tsuchida, K.1
-
62
-
-
44849140764
-
A phase 1/2trial of MYO-029 in adult subjects with muscular dystrophy
-
doi:10.1002/ana.21338
-
Wagner KR, Fleckenstein JL, Amato AA, Barohn RJ, Bushby K, Escolar DM, Flanigan KM, Pestronk A, Tawil R, Wolfe GI, Eagle M, Florence JM, King WM, Pandya S, Straub V, Juneau P, Meyers K, Csimma C, Araujo T, Allen R, Parsons SA, Wozney JM, Lavallie ER, Mendell JR (2008) A phase 1/2trial of MYO-029 in adult subjects with muscular dystrophy. Ann Neurol 63(5):561-571. doi:10.1002/ana. 21338
-
(2008)
Ann Neurol
, vol.63
, Issue.5
, pp. 561-571
-
-
Wagner, K.R.1
Fleckenstein, J.L.2
Amato, A.A.3
Barohn, R.J.4
Bushby, K.5
Escolar, D.M.6
Flanigan, K.M.7
Pestronk, A.8
Tawil, R.9
Wolfe, G.I.10
Eagle, M.11
Florence, J.M.12
King, W.M.13
Pandya, S.14
Straub, V.15
Juneau, P.16
Meyers, K.17
Csimma, C.18
Araujo, T.19
Allen, R.20
Parsons, S.A.21
Wozney, J.M.22
Lavallie, E.R.23
Mendell, J.R.24
more..
-
63
-
-
0036604230
-
Insulin-like growth factor-1 and myostatin mRNA expression in muscle: Comparison between 62-77 and 21-31 yr old men
-
Welle S, Bhatt K, Shah B, Thornton C (2002) Insulin-like growth factor-1 and myostatin mRNA expression in muscle: comparison between 62-77 and 21-31 yr old men. ExpGerontol 37(6):833-839
-
(2002)
ExpGerontol
, vol.37
, Issue.6
, pp. 833-839
-
-
Welle, S.1
Bhatt, K.2
Shah, B.3
Thornton, C.4
-
64
-
-
0036959537
-
Serum myostatinimmunoreactive protein is increased in 60-92 year old women and men with muscle wasting
-
Yarasheski KE, Bhasin S, Sinha-Hikim I, Pak-Loduca J, Gonzalez-Cadavid NF (2002) Serum myostatinimmunoreactive protein is increased in 60-92 year old women and men with muscle wasting. J Nutr Health Aging 6(5):343-348
-
(2002)
J Nutr Health Aging
, vol.6
, Issue.5
, pp. 343-348
-
-
Yarasheski, K.E.1
Bhasin, S.2
Sinha-Hikim, I.3
Pak-Loduca, J.4
Gonzalez-Cadavid, N.F.5
-
65
-
-
34548492947
-
Relationships between transforming growth factor-beta1, myostatin, and decorin: Implications for skeletal muscle fibrosis
-
doi:10.1074/jbc.M704146200
-
Zhu J, Li Y, Shen W, Qiao C, Ambrosio F, Lavasani M, Nozaki M, Branca MF, Huard J (2007) Relationships between transforming growth factor-beta1, myostatin, and decorin: implications for skeletal muscle fibrosis. J Biol Chem 282 (35):25852-25863. doi:10.1074/jbc.M704146200
-
(2007)
J Biol Chem
, vol.282
, Issue.35
, pp. 25852-25863
-
-
Zhu, J.1
Li, Y.2
Shen, W.3
Qiao, C.4
Ambrosio, F.5
Lavasani, M.6
Nozaki, M.7
Branca, M.F.8
Huard, J.9
|