Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice

American Journal of Pathology

Volumn 178, Issue 2, 2011, Pages 784-793

  Lawlor, Michael W ^a   Read, Benjamin P ^a   Edelstein, Rachel ^a   Yang, Nicole ^a   Pierson, Christopher R ^b   Stein, Matthew J ^a   Wermer Colan, Ariana ^a   Buj Bello, Anna ^c   Lachey, Jennifer L ^d   Seehra, Jasbir S ^d   Beggs, Alan H ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c GÉNÉTHON   (France)

^d Acceleron Pharma Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR; ACTIVIN RECEPTOR TYPE IIB MFC; HYBRID PROTEIN; MYOTUBULARIN; PHOSPHATASE; RAP 031; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CELL SIZE; CONTROLLED STUDY; DEATH; DRUG MECHANISM; ENZYME INHIBITION; GRIP STRENGTH; HISTOPATHOLOGY; LIFESPAN; MALE; MOUSE; MUSCLE BIOPSY; MUSCLE CELL; MUSCLE GROWTH; MUSCLE HYPERTROPHY; MUSCLE STRENGTH; MYOPATHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RESPIRATORY FAILURE; SKELETAL MUSCLE; SURVIVAL; WEAKNESS; WEIGHT REDUCTION; WESTERN BLOTTING; X CHROMOSOME LINKED DISORDER; X LINKED MYOTUBULAR MYOPATHY;

EID: 79951842509     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2010.10.035     Document Type: Article

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