메뉴 건너뛰기




Volumn 211, Issue 1, 2014, Pages 5-13

Initiation of MLL-rearranged AML is dependent on C/EBPα

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; MIXED LINEAGE LEUKEMIA PROTEIN; TRANSCRIPTION FACTOR HOXA9;

EID: 84892504696     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20130932     Document Type: Article
Times cited : (62)

References (27)
  • 1
    • 8644278033 scopus 로고    scopus 로고
    • Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein
    • Ayton, P.M., E.H. Chen, and M.L. Cleary. 2004. Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein. Mol. Cell. Biol. 24:10470-10478. http://dx.doi.org/10.1128/MCB.24.23.10470-10478.2004.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 10470-10478
    • Ayton, P.M.1    Chen, E.H.2    Cleary, M.L.3
  • 2
    • 33751267902 scopus 로고    scopus 로고
    • Acute myeloid leukaemia
    • Estey, E., and H. Döhner. 2006. Acute myeloid leukaemia. Lancet. 368:1894-1907. http://dx.doi.org/10.1016/S0140-6736(06)69780-8.
    • (2006) Lancet. , vol.368 , pp. 1894-1907
    • Estey, E.1    Döhner, H.2
  • 3
    • 78650444882 scopus 로고    scopus 로고
    • Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia
    • Gentles, A.J., S.K. Plevritis, R. Majeti, and A.A. Alizadeh. 2010. Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia. JAMA. 304:2706-2715. http://dx.doi.org/10 .1001/jama.2010.1862.
    • (2010) JAMA. , vol.304 , pp. 2706-2715
    • Gentles, A.J.1    Plevritis, S.K.2    Majeti, R.3    Alizadeh, A.A.4
  • 4
    • 77955134007 scopus 로고    scopus 로고
    • Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group
    • Haferlach, T., A. Kohlmann, L. Wieczorek, G. Basso, G.T. Kronnie, M.C. Béné, J. De Vos, J.M. Hernández, W.K. Hofmann, K.I. Mills, et al. 2010. Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group. J. Clin. Oncol. 28:2529-2537. http://dx.doi.org/10.1200/JCO.2009.23.4732.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 2529-2537
    • Haferlach, T.1    Kohlmann, A.2    Wieczorek, L.3    Basso, G.4    Kronnie, G.T.5    Béné, M.C.6    De Vos, J.7    Hernández, J.M.8    Hofmann, W.K.9    Mills, K.I.10
  • 5
    • 84862015400 scopus 로고    scopus 로고
    • Phosphorylation of serine 248 of C/EBPα is dispensable for myelopoiesis but its disruption leads to a low penetrant myeloid disorder with long latency
    • Hasemann, M.S., M.B. Schuster, A.K. Frank, K. Theilgaard-Mönch, T.A. Pedersen, C. Nerlov, and B.T. Porse. 2012. Phosphorylation of serine 248 of C/EBPα is dispensable for myelopoiesis but its disruption leads to a low penetrant myeloid disorder with long latency. PLoS ONE. 7:e38841. http://dx.doi.org/10.1371/journal.pone.0038841.
    • (2012) PLoS ONE. , vol.7
    • Hasemann, M.S.1    Schuster, M.B.2    Frank, A.K.3    Theilgaard-Mönch, K.4    Pedersen, T.A.5    Nerlov, C.6    Porse, B.T.7
  • 6
    • 73449134439 scopus 로고    scopus 로고
    • Gene set enrichment analysis made simple
    • Irizarry, R.A., C. Wang, Y. Zhou, and T.P. Speed. 2009. Gene set enrichment analysis made simple. Stat. Methods Med. Res. 18:565-575. http://dx.doi.org/10.1177/0962280209351908.
    • (2009) Stat. Methods Med. Res. , vol.18 , pp. 565-575
    • Irizarry, R.A.1    Wang, C.2    Zhou, Y.3    Speed, T.P.4
  • 7
    • 35548934558 scopus 로고    scopus 로고
    • MLL translocations, histone modifications and leukaemia stem-cell development
    • Krivtsov, A.V., and S.A. Armstrong. 2007. MLL translocations, histone modifications and leukaemia stem-cell development. Nat. Rev. Cancer. 7:823-833. http://dx.doi.org/10.1038/nrc2253.
    • (2007) Nat. Rev. Cancer. , vol.7 , pp. 823-833
    • Krivtsov, A.V.1    Armstrong, S.A.2
  • 8
    • 0032126633 scopus 로고    scopus 로고
    • Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
    • Kroon, E., J. Krosl, U. Thorsteinsdottir, S. Baban, A.M. Buchberg, and G. Sauvageau. 1998. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J. 17:3714-3725. http://dx.doi.org/10.1093/emboj/17.13.3714.
    • (1998) EMBO J. , vol.17 , pp. 3714-3725
    • Kroon, E.1    Krosl, J.2    Thorsteinsdottir, U.3    Baban, S.4    Buchberg, A.M.5    Sauvageau, G.6
  • 9
    • 0029155706 scopus 로고
    • Inducible gene targeting in mice
    • Kühn, R., F. Schwenk, M. Aguet, and K. Rajewsky. 1995. Inducible gene targeting in mice. Science. 269:1427-1429. http://dx.doi.org/10.1126/science.7660125.
    • (1995) Science. , vol.269 , pp. 1427-1429
    • Kühn, R.1    Schwenk, F.2    Aguet, M.3    Rajewsky, K.4
  • 10
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead, B., C. Trapnell, M. Pop, and S.L. Salzberg. 2009. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 10:R25. http://dx.doi.org/10.1186/gb-2009-10-3-r25.
    • (2009) Genome Biol. , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 11
    • 0030765649 scopus 로고    scopus 로고
    • Disruption of the c/ebp alpha gene in adult mouse liver
    • Lee, Y.H., B. Sauer, P.F. Johnson, and F.J. Gonzalez. 1997. Disruption of the c/ebp alpha gene in adult mouse liver. Mol. Cell. Biol. 17:6014-6022.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6014-6022
    • Lee, Y.H.1    Sauer, B.2    Johnson, P.F.3    Gonzalez, F.J.4
  • 12
    • 84856916060 scopus 로고    scopus 로고
    • The pathogenesis of mixed-lineage leukemia
    • Muntean, A.G., and J.L. Hess. 2012. The pathogenesis of mixed-lineage leukemia. Annu. Rev. Pathol. 7:283-301. http://dx.doi.org/10.1146/annurev-pathol-011811-132434.
    • (2012) Annu. Rev. Pathol. , vol.7 , pp. 283-301
    • Muntean, A.G.1    Hess, J.L.2
  • 13
    • 2342544921 scopus 로고    scopus 로고
    • C/EBPalpha mutations in acute myeloid leukaemias
    • Nerlov, C. 2004. C/EBPalpha mutations in acute myeloid leukaemias. Nat. Rev. Cancer. 4:394-400. http://dx.doi.org/10.1038/nrc1363.
    • (2004) Nat. Rev. Cancer. , vol.4 , pp. 394-400
    • Nerlov, C.1
  • 14
    • 79959960773 scopus 로고    scopus 로고
    • The diverse functions of Dot1 and H3K79 methylation
    • Nguyen, A.T., and Y. Zhang. 2011. The diverse functions of Dot1 and H3K79 methylation. Genes Dev. 25:1345-1358. http://dx.doi.org/10.1101/gad .2057811.
    • (2011) Genes Dev. , vol.25 , pp. 1345-1358
    • Nguyen, A.T.1    Zhang, Y.2
  • 15
    • 85027927682 scopus 로고    scopus 로고
    • Molecular mechanisms underlying deregulation of C/EBPalpha in acute myeloid leukemia
    • Reckzeh, K., and J. Cammenga. 2010. Molecular mechanisms underlying deregulation of C/EBPalpha in acute myeloid leukemia. Int. J. Hematol. 91:557-568. http://dx.doi.org/10.1007/s12185-010-0573-1.
    • (2010) Int. J. Hematol. , vol.91 , pp. 557-568
    • Reckzeh, K.1    Cammenga, J.2
  • 16
    • 67650770689 scopus 로고    scopus 로고
    • The molecular biology of mixed lineage leukemia
    • Slany, R.K. 2009. The molecular biology of mixed lineage leukemia. Haematologica. 94:984-993. http://dx.doi.org/10.3324/haematol.2008.002436.
    • (2009) Haematologica. , vol.94 , pp. 984-993
    • Slany, R.K.1
  • 17
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Smyth, G.K. 2004. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol. 3:3.
    • (2004) Stat. Appl. Genet. Mol. Biol. , vol.3 , pp. 3
    • Smyth, G.K.1
  • 18
    • 33749440584 scopus 로고    scopus 로고
    • Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia
    • Somervaille, T.C., and M.L. Cleary. 2006. Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia. Cancer Cell. 10:257-268. http://dx.doi.org/10.1016/j.ccr.2006 .08.020.
    • (2006) Cancer Cell. , vol.10 , pp. 257-268
    • Somervaille, T.C.1    Cleary, M.L.2
  • 25
    • 63849241865 scopus 로고    scopus 로고
    • Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome
    • Wouters, B.J., B. Löwenberg, C.A. Erpelinck-Verschueren, W.L. van Putten, P.J. Valk, and R. Delwel. 2009. Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome. Blood. 113:3088-3091. http://dx.doi.org/10.1182/blood-2008-09-179895.
    • (2009) Blood. , vol.113 , pp. 3088-3091
    • Wouters, B.J.1    Löwenberg, B.2    Erpelinck-Verschueren, C.A.3    van Putten, W.L.4    Valk, P.J.5    Delwel, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.