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Volumn 10, Issue 1, 2014, Pages 141-151

Metabolite profiling reveals new insights into the regulation of serum urate in humans

(21)  Albrecht, Eva a   Waldenberger, Melanie a   Krumsiek, Jan a   Evans, Anne M b   Jeratsch, Ulli a   Breier, Michaela a   Adamski, Jerzy a,c,k   Koenig, Wolfgang d   Zeilinger, Sonja a   Fuchs, Christiane a   Klopp, Norman a,e   Theis, Fabian J a   Wichmann, H Erich a,f,g   Suhre, Karsten a,h   Illig, Thomas a,e   Strauch, Konstantin a,f   Peters, Annette a,i   Gieger, Christian a   Kastenmüller, Gabi a   Doering, Angela a   more..


Author keywords

Allopurinol; Gaussian Graphical Modeling; Metabolite network; Pathway reconstruction; Purine metabolism; Uric acid

Indexed keywords

ARGININE; ASPARTAME; CAFFEINE; CITRIC ACID; DIPEPTIDE; EPIANDROSTERONE; HISTIDINE; HYDROXYBUTYRIC ACID; HYPOXANTHINE; INOSINE; METHIONINE; PHENYLALANINE; PRASTERONE SULFATE; STEROID; TRYPTOPHAN; TYROSINE; URATE; URIDINE; XANTHINE;

EID: 84892483679     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-013-0565-2     Document Type: Article
Times cited : (55)

References (48)
  • 1
    • 80052406750 scopus 로고    scopus 로고
    • Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis
    • Ahn, S. Y., et al. (2011). Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis. Journal of Biological Chemistry, 286, 31522-31531.
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 31522-31531
    • Ahn, S.Y.1
  • 2
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y., & Hochberg, Y. (1995). Controlling the false discovery rate: A practical and powerful approach to multiple testing. Journal of the Royal Statistical Society, 57, 289-300.
    • (1995) Journal of the Royal Statistical Society , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 3
    • 0035733108 scopus 로고    scopus 로고
    • The control of the false discovery rate in multiple testing under dependency
    • Benjamini, Y., & Yekutieli, D. (2001). The control of the false discovery rate in multiple testing under dependency. The Annals of Statistics, 29, 1165-1188.
    • (2001) The Annals of Statistics , vol.29 , pp. 1165-1188
    • Benjamini, Y.1    Yekutieli, D.2
  • 4
    • 1642484244 scopus 로고    scopus 로고
    • Xanthine oxidoreductase and cardiovascular disease: Molecular mechanisms and pathophysiological implications
    • Berry, C. E., & Hare, J. M. (2004). Xanthine oxidoreductase and cardiovascular disease: Molecular mechanisms and pathophysiological implications. Journal of Physiology, 555, 589-606.
    • (2004) Journal of Physiology , vol.555 , pp. 589-606
    • Berry, C.E.1    Hare, J.M.2
  • 6
    • 34250645316 scopus 로고    scopus 로고
    • Coffee, tea, and caffeine consumption and serum uric acid level: the third national health and nutrition examination survey
    • Choi, H. K., & Curhan, G. (2007). Coffee, tea, and caffeine consumption and serum uric acid level: the third national health and nutrition examination survey. Arthritis and Rheumatism, 57, 816-821.
    • (2007) Arthritis and Rheumatism , vol.57 , pp. 816-821
    • Choi, H.K.1    Curhan, G.2
  • 7
    • 0023655407 scopus 로고
    • Protein damage and degradation by oxygen radicals. II. Modification of amino acids
    • Davies, K. J., Delsignore, M. E., & Lin, S. W. (1987). Protein damage and degradation by oxygen radicals. II. Modification of amino acids. Journal of Biological Chemistry, 262, 9902-9907.
    • (1987) Journal of Biological Chemistry , vol.262 , pp. 9902-9907
    • Davies, K.J.1    Delsignore, M.E.2    Lin, S.W.3
  • 8
    • 41449093735 scopus 로고    scopus 로고
    • SLC2A9 influences uric acid concentrations with pronounced sex-specific effects
    • Doring, A., et al. (2008). SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. Nature Genetics, 40, 430-436.
    • (2008) Nature Genetics , vol.40 , pp. 430-436
    • Doring, A.1
  • 9
    • 68849083050 scopus 로고    scopus 로고
    • Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems
    • Evans, A. M., DeHaven, C. D., Barrett, T., Mitchell, M., & Milgram, E. (2009). Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems. Analytical Chemistry, 81, 6656-6667.
    • (2009) Analytical Chemistry , vol.81 , pp. 6656-6667
    • Evans, A.M.1    DeHaven, C.D.2    Barrett, T.3    Mitchell, M.4    Milgram, E.5
  • 10
    • 3042844018 scopus 로고    scopus 로고
    • Association between serum homocysteine and markers of impaired kidney function in adults in the United States
    • Francis, M. E., Eggers, P. W., Hostetter, T. H., & Briggs, J. P. (2004). Association between serum homocysteine and markers of impaired kidney function in adults in the United States. Kidney International, 66, 303-312.
    • (2004) Kidney International , vol.66 , pp. 303-312
    • Francis, M.E.1    Eggers, P.W.2    Hostetter, T.H.3    Briggs, J.P.4
  • 11
    • 0032890885 scopus 로고    scopus 로고
    • Xanthine oxidase inhibition by allopurinol affects the reliability of urinary caffeine metabolic ratios as markers for N-acetyltransferase 2 and CYP1A2 activities
    • Fuchs, P., Haefeli, W. E., Ledermann, H. R., & Wenk, M. (1999). Xanthine oxidase inhibition by allopurinol affects the reliability of urinary caffeine metabolic ratios as markers for N-acetyltransferase 2 and CYP1A2 activities. European Journal of Clinical Pharmacology, 54, 869-876.
    • (1999) European Journal of Clinical Pharmacology , vol.54 , pp. 869-876
    • Fuchs, P.1    Haefeli, W.E.2    Ledermann, H.R.3    Wenk, M.4
  • 12
    • 67449085150 scopus 로고    scopus 로고
    • Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress
    • George, J., & Struthers, A. D. (2009). Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress. Vasc Health Risk Manag, 5, 265-272.
    • (2009) Vasc Health Risk Manag , vol.5 , pp. 265-272
    • George, J.1    Struthers, A.D.2
  • 15
    • 13144253218 scopus 로고    scopus 로고
    • Uric acid: A new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes mellitus: The urate redox shuttle
    • Hayden, M. R., & Tyagi, S. C. (2004). Uric acid: A new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes mellitus: The urate redox shuttle. Nutrition & Metabolism (London), 1, 10.
    • (2004) Nutrition & Metabolism (London) , vol.1 , pp. 10
    • Hayden, M.R.1    Tyagi, S.C.2
  • 16
    • 0019877327 scopus 로고
    • Studies on the oxidative half-reaction of xanthine oxidase
    • Hille, R., & Massey, V. (1981). Studies on the oxidative half-reaction of xanthine oxidase. Journal of Biological Chemistry, 256, 9090-9095.
    • (1981) Journal of Biological Chemistry , vol.256 , pp. 9090-9095
    • Hille, R.1    Massey, V.2
  • 17
    • 23844467739 scopus 로고    scopus 로고
    • KORA-a research platform for population based health research
    • Holle, R., Happich, M., Lowel, H., & Wichmann, H. E. (2005). KORA-a research platform for population based health research. Gesundheitswesen, 67(Suppl 1), 19-25.
    • (2005) Gesundheitswesen , vol.67 , Issue.SUPPL. 1 , pp. 19-25
    • Holle, R.1    Happich, M.2    Lowel, H.3    Wichmann, H.E.4
  • 18
    • 55549115068 scopus 로고    scopus 로고
    • Homocysteine level and coronary heart disease incidence: A systematic review and meta-analysis
    • Humphrey, L. L., Fu, R., Rogers, K., Freeman, M., & Helfand, M. (2008). Homocysteine level and coronary heart disease incidence: A systematic review and meta-analysis. Mayo Clinic Proceedings, 83, 1203-1212.
    • (2008) Mayo Clinic Proceedings , vol.83 , pp. 1203-1212
    • Humphrey, L.L.1    Fu, R.2    Rogers, K.3    Freeman, M.4    Helfand, M.5
  • 19
    • 0037213731 scopus 로고    scopus 로고
    • Urate transport via human PAH transporter hOAT1 and its gene structure
    • Ichida, K., et al. (2003). Urate transport via human PAH transporter hOAT1 and its gene structure. Kidney International, 63, 143-155.
    • (2003) Kidney International , vol.63 , pp. 143-155
    • Ichida, K.1
  • 20
    • 79958132608 scopus 로고    scopus 로고
    • Uric acid as a cardiometabolic risk factor: To be or not to be
    • Kanbay, M., Afsar, B., & Covic, A. (2011). Uric acid as a cardiometabolic risk factor: To be or not to be. Contributions to Nephrology, 171, 62-67.
    • (2011) Contributions to Nephrology , vol.171 , pp. 62-67
    • Kanbay, M.1    Afsar, B.2    Covic, A.3
  • 21
    • 39749167785 scopus 로고    scopus 로고
    • Uric acid, type 2 diabetes, and cardiovascular diseases: Fueling the common soil hypothesis?
    • Koenig, W., & Meisinger, C. (2008). Uric acid, type 2 diabetes, and cardiovascular diseases: Fueling the common soil hypothesis? Clinical Chemistry, 54, 231-233.
    • (2008) Clinical Chemistry , vol.54 , pp. 231-233
    • Koenig, W.1    Meisinger, C.2
  • 22
    • 67651056502 scopus 로고    scopus 로고
    • Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations
    • Kolz, M., et al. (2009). Meta-analysis of 28, 141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genetics, 5, e1000504.
    • (2009) PLoS Genetics , vol.5
    • Kolz, M.1
  • 23
    • 84947899575 scopus 로고    scopus 로고
    • Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
    • Kottgen, A., et al. (2013). Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nature Genetics, 45, 145-154.
    • (2013) Nature Genetics , vol.45 , pp. 145-154
    • Kottgen, A.1
  • 24
    • 79251567361 scopus 로고    scopus 로고
    • Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data
    • Krumsiek, J., Suhre, K., Illig, T., Adamski, J., & Theis, F. J. (2011). Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data. BMC Systems Biology, 5, 21.
    • (2011) BMC Systems Biology , vol.5 , pp. 21
    • Krumsiek, J.1    Suhre, K.2    Illig, T.3    Adamski, J.4    Theis, F.J.5
  • 25
    • 84868112190 scopus 로고    scopus 로고
    • Mining the unknown: A systems approach to metabolite identification Combining genetic and metabolic information
    • Krumsiek, J., et al. (2012). Mining the unknown: A systems approach to metabolite identification Combining genetic and metabolic information. PLoS Genetics, 8, e1003005.
    • (2012) PLoS Genetics , vol.8
    • Krumsiek, J.1
  • 26
    • 0035876367 scopus 로고    scopus 로고
    • A comparison of chronic aspartame exposure to aspirin on inflammation, hyperalgesia and open field activity following carrageenan-induced monoarthritis
    • LaBuda, C. J., & Fuchs, P. N. (2001). A comparison of chronic aspartame exposure to aspirin on inflammation, hyperalgesia and open field activity following carrageenan-induced monoarthritis. Life Sciences, 69, 443-454.
    • (2001) Life Sciences , vol.69 , pp. 443-454
    • LaBuda, C.J.1    Fuchs, P.N.2
  • 27
    • 61849180106 scopus 로고
    • Testing hypotheses concerning partial correlations: Some methods and discussion
    • Levy, K. J., & Narula, S. C. (1978). Testing hypotheses concerning partial correlations: Some methods and discussion. International statistical review 46.
    • (1978) International Statistical Review , pp. 46
    • Levy, K.J.1    Narula, S.C.2
  • 28
    • 37349008492 scopus 로고    scopus 로고
    • The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts
    • Li, S., et al. (2007). The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts. PLoS Genetics, 3, e194.
    • (2007) PLoS Genetics , vol.3
    • Li, S.1
  • 29
    • 35349014082 scopus 로고    scopus 로고
    • Homocystein and carotid atherosclerosis in chronic renal failure
    • Lubomirova, M., Tzoncheva, A., Petrova, J., & Kiperova, B. (2007). Homocystein and carotid atherosclerosis in chronic renal failure. Hippokratia, 11, 205-209.
    • (2007) Hippokratia , vol.11 , pp. 205-209
    • Lubomirova, M.1    Tzoncheva, A.2    Petrova, J.3    Kiperova, B.4
  • 31
    • 84864290717 scopus 로고    scopus 로고
    • Metabolomics in the fields of oncology: a review of recent research
    • Ma, Y., Zhang, P., Yang, Y., Wang, F., & Qin, H. (2012). Metabolomics in the fields of oncology: a review of recent research. Mol Biol Rep, 39(7), 7505-7511.
    • (2012) Mol Biol Rep , vol.39 , Issue.7 , pp. 7505-7511
    • Ma, Y.1    Zhang, P.2    Yang, Y.3    Wang, F.4    Qin, H.5
  • 32
    • 0028936881 scopus 로고
    • Role of blood pressure, uric acid, and hemorheological parameters on plasma homocyst(e)ine concentration
    • Malinow, M. R., et al. (1995). Role of blood pressure, uric acid, and hemorheological parameters on plasma homocyst(e)ine concentration. Atherosclerosis, 114, 175-183.
    • (1995) Atherosclerosis , vol.114 , pp. 175-183
    • Malinow, M.R.1
  • 33
    • 79959420445 scopus 로고    scopus 로고
    • Dietary aspartyl-phenylalanine-1-methyl ester delays osteoarthritis and prevents associated bone loss in STR/ORT mice
    • Manion, C. V., Hochgeschwender, U., Edmundson, A. B., Hugli, T. E., & Gabaglia, C. R. (2011). Dietary aspartyl-phenylalanine-1-methyl ester delays osteoarthritis and prevents associated bone loss in STR/ORT mice. Rheumatology (Oxford), 50, 1244-1249.
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 1244-1249
    • Manion, C.V.1    Hochgeschwender, U.2    Edmundson, A.B.3    Hugli, T.E.4    Gabaglia, C.R.5
  • 34
    • 80052314547 scopus 로고    scopus 로고
    • Discovery of sexual dimorphisms in metabolic and genetic biomarkers
    • Mittelstrass, K., et al. (2011). Discovery of sexual dimorphisms in metabolic and genetic biomarkers. PLoS Genetics, 7, e1002215.
    • (2011) PLoS Genetics , vol.7
    • Mittelstrass, K.1
  • 36
    • 84865324339 scopus 로고    scopus 로고
    • Tryptophan-containing milk protein-derived dipeptides inhibit xanthine oxidase
    • doi:10.1016/j.peptides.2012.07.030
    • Nongonierma, A. B., & Fitzgerald, R. J. (2012). Tryptophan-containing milk protein-derived dipeptides inhibit xanthine oxidase. Peptides, 37, 263-272. doi: 10. 1016/j. peptides. 2012. 07. 030.
    • (2012) Peptides , vol.37 , pp. 263-272
    • Nongonierma, A.B.1    Fitzgerald, R.J.2
  • 37
    • 0027964207 scopus 로고
    • Xanthine dehydrogenase and xanthine oxidase activity and gene expression in renal epithelial cells. Cytokine and steroid regulation
    • Pfeffer, K. D., Huecksteadt, T. P., & Hoidal, J. R. (1994). Xanthine dehydrogenase and xanthine oxidase activity and gene expression in renal epithelial cells. Cytokine and steroid regulation. Journal of Immunology, 153, 1789-1797.
    • (1994) Journal of Immunology , vol.153 , pp. 1789-1797
    • Pfeffer, K.D.1    Huecksteadt, T.P.2    Hoidal, J.R.3
  • 38
    • 78951474876 scopus 로고    scopus 로고
    • Experimental evaluation of antipyretic and analgesic activity of aspartame
    • Pradhan, S., Shah, U. H., Mathur, A., & Sharma, S. (2011). Experimental evaluation of antipyretic and analgesic activity of aspartame. Indian Journal of Pharmacology, 43, 89-90.
    • (2011) Indian Journal of Pharmacology , vol.43 , pp. 89-90
    • Pradhan, S.1    Shah, U.H.2    Mathur, A.3    Sharma, S.4
  • 40
    • 0015322565 scopus 로고
    • Dehydroepiandrosterone (3-hydroxy-5-androsten-17-one) metabolism in gout
    • Sparagana, M., & Phillips, G. (1972). Dehydroepiandrosterone (3-hydroxy-5-androsten-17-one) metabolism in gout. Steroids, 19, 477-491.
    • (1972) Steroids , vol.19 , pp. 477-491
    • Sparagana, M.1    Phillips, G.2
  • 41
    • 80052398214 scopus 로고    scopus 로고
    • Human metabolic individuality in biomedical and pharmaceutical research
    • Suhre, K., et al. (2011). Human metabolic individuality in biomedical and pharmaceutical research. Nature, 477, 54-60.
    • (2011) Nature , vol.477 , pp. 54-60
    • Suhre, K.1
  • 43
    • 41349103917 scopus 로고    scopus 로고
    • SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout
    • Vitart, V., et al. (2008). SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. Nature Genetics, 40, 437-442.
    • (2008) Nature Genetics , vol.40 , pp. 437-442
    • Vitart, V.1
  • 44
    • 38749149611 scopus 로고    scopus 로고
    • Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia
    • Wallace, C., et al. (2008). Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. American Journal of Human Genetics, 82, 139-149.
    • (2008) American Journal of Human Genetics , vol.82 , pp. 139-149
    • Wallace, C.1
  • 45
    • 23844472247 scopus 로고    scopus 로고
    • KORA-gen-resource for population genetics, controls and a broad spectrum of disease phenotypes
    • Wichmann, H. E., Gieger, C., & Illig, T. (2005). KORA-gen-resource for population genetics, controls and a broad spectrum of disease phenotypes. Gesundheitswesen, 67(Suppl 1), S26-S30.
    • (2005) Gesundheitswesen , vol.67 , Issue.SUPPL. 1
    • Wichmann, H.E.1    Gieger, C.2    Illig, T.3
  • 46
    • 79954998791 scopus 로고    scopus 로고
    • Remote communication through solute carriers and ATP binding cassette drug transporter pathways: an update on the remote sensing and signaling hypothesis
    • Wu, W., Dnyanmote, A. V., & Nigam, S. K. (2011). Remote communication through solute carriers and ATP binding cassette drug transporter pathways: an update on the remote sensing and signaling hypothesis. Molecular Pharmacology, 79, 795-805.
    • (2011) Molecular Pharmacology , vol.79 , pp. 795-805
    • Wu, W.1    Dnyanmote, A.V.2    Nigam, S.K.3
  • 47
    • 16544385451 scopus 로고    scopus 로고
    • Interrelationship between methionine and cystine of early Peking ducklings
    • Xie, M., et al. (2004). Interrelationship between methionine and cystine of early Peking ducklings. Poultry Science, 83, 1703-1708.
    • (2004) Poultry Science , vol.83 , pp. 1703-1708
    • Xie, M.1
  • 48
    • 79952797990 scopus 로고    scopus 로고
    • Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors
    • Yang, Q., et al. (2010). Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circulation Cardiovascular Genetics, 3, 523-530.
    • (2010) Circulation Cardiovascular Genetics , vol.3 , pp. 523-530
    • Yang, Q.1


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