Mining the Unknown: A Systems Approach to Metabolite Identification Combining Genetic and Metabolic Information

PLoS Genetics

Volumn 8, Issue 10, 2012, Pages

  Krumsiek, Jan ^a   Suhre, Karsten ^a,b   Evans, Anne M ^c   Mitchell, Matthew W ^c   Mohney, Robert P ^c   Milburn, Michael V ^c   Wägele, Brigitte ^a,d   Römisch Margl, Werner ^a   Illig, Thomas ^a,e   Adamski, Jerzy ^a,d   Gieger, Christian ^a   Theis, Fabian J ^a,d   Kastenmüller, Gabi ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b WEILL CORNELL MEDICAL COLLEGE   (Qatar)

^c METABOLON INC   (United States)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; CYTOCHROME P450 2C18; CYTOCHROME P450 3A5; ORGANIC CATION TRANSPORTER 2;

ARTICLE; BLOOD SAMPLING; COMT GENE; CONTROLLED STUDY; CYP2C18 GENE; CYP3A5 GENE; GBA3 GENE; GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; HUMAN; MATHEMATICAL MODEL; METABOLITE; METABOLOMICS; MOLECULAR DYNAMICS; PREDICTION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SLC22A2 GENE; UGT3A1 GENE; VALIDATION PROCESS;

COMPUTATIONAL BIOLOGY; DATA MINING; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HUMANS; METABOLOME; METABOLOMICS; MODELS, STATISTICAL; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION;

EID: 84868112190     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003005     Document Type: Article

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