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Volumn 34, Issue 3, 2014, Pages 415-427

Regulation of NO synthesis, local inflammation, and innate: Immunity to pathogens by BET family proteins

Author keywords

[No Author keywords available]

Indexed keywords

BET PROTEIN; BRD2 PROTEIN; BRD3 PROTEIN; BRD4 PROTEIN; DEXTRAN SULFATE; INDUCIBLE NITRIC OXIDE SYNTHASE; JQ1 PROTEIN; PROTEIN; PROTEIN INHIBITOR; RNA POLYMERASE; SERINE; UNCLASSIFIED DRUG;

EID: 84892469287     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01353-13     Document Type: Article
Times cited : (60)

References (79)
  • 2
    • 74549167783 scopus 로고    scopus 로고
    • Regulation of adaptive immunity by the innate immune system
    • Iwasaki A, Medzhitov R. 2010. Regulation of adaptive immunity by the innate immune system. Science 327:291-295. http://dx.doi.org/10.1126 /science.1183021.
    • (2010) Science , vol.327 , pp. 291-295
    • Iwasaki, A.1    Medzhitov, R.2
  • 3
    • 0036327382 scopus 로고    scopus 로고
    • The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity
    • Portnoy DA, Auerbuch V, Glomski IJ. 2002. The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity. J. Cell Biol. 158:409-414. http://dx.doi.org/10 .1083/jcb.200205009.
    • (2002) J. Cell Biol , vol.158 , pp. 409-414
    • Portnoy, D.A.1    Auerbuch, V.2    Glomski, I.J.3
  • 4
    • 33646844623 scopus 로고    scopus 로고
    • Listeria monocytogenes: a multifaceted model
    • Hamon M, Bierne H, Cossart P. 2006. Listeria monocytogenes: a multifaceted model. Nat. Rev. Microbiol. 4:423-434. http://dx.doi.org/10.1038/nrmicro1413.
    • (2006) Nat. Rev. Microbiol , vol.4 , pp. 423-434
    • Hamon, M.1    Bierne, H.2    Cossart, P.3
  • 7
    • 77954070545 scopus 로고    scopus 로고
    • c- di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response
    • Woodward JJ, Iavarone AT, Portnoy DA. 2010. c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 328:1703-1705. http://dx.doi.org/10.1126/science.1189801.
    • (2010) Science , vol.328 , pp. 1703-1705
    • Woodward, J.J.1    Iavarone, A.T.2    Portnoy, D.A.3
  • 8
    • 79251506939 scopus 로고    scopus 로고
    • The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides
    • Sauer J-D, Sotelo-Troha K, von Moltke, J, Monroe KM, Rae CS, Brubaker SW, Hyodo M, Hayakawa Y, Woodward JJ, Portnoy DA, Vance RE. 2011. The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infect. Immun. 79:688-694. http://dx.doi.org/10.1128/IAI.00999-10.
    • (2011) Infect. Immun , vol.79 , pp. 688-694
    • Sauer, J.-D.1    Sotelo-Troha, K.2    von Moltke, J.3    Monroe, K.M.4    Rae, C.S.5    Brubaker, S.W.6    Hyodo, M.7    Hayakawa, Y.8    Woodward, J.J.9    Portnoy, D.A.10    Vance, R.E.11
  • 9
    • 0037108761 scopus 로고    scopus 로고
    • Innate recognition of bacteria by a macrophage cytosolic surveillance pathway
    • O'Riordan M, Yi CH, Gonzales R, Lee KD, Portnoy DA. 2002. Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc. Natl. Acad. Sci. U. S. A. 99:13861-13866. http://dx.doi.org/10.1073 /pnas.202476699.
    • (2002) Proc. Natl. Acad. Sci. U. S. A , vol.99 , pp. 13861-13866
    • O'Riordan, M.1    Yi, C.H.2    Gonzales, R.3    Lee, K.D.4    Portnoy, D.A.5
  • 11
    • 0036731485 scopus 로고    scopus 로고
    • Stats: transcriptional control and biological impact
    • Levy DE, Darnell JE, Jr. 2002. Stats: transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 3:651-662. http://dx.doi.org/10.1038 /nrm909.
    • (2002) Nat. Rev. Mol. Cell Biol , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell Jr., J.E.2
  • 14
    • 0001378811 scopus 로고    scopus 로고
    • Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharideinduced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene
    • Gao JJ, Filla MB, Fultz MJ, Vogel SN, Russell SW, Murphy WJ. 1998. Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharideinduced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene. J. Immunol. 161:4803-4810.
    • (1998) J. Immunol. , vol.161 , pp. 4803-4810
    • Gao, J.J.1    Filla, M.B.2    Fultz, M.J.3    Vogel, S.N.4    Russell, S.W.5    Murphy, W.J.6
  • 15
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan C. 2001. Nitric oxide and the immune response. Nat. Immunol. 2:907-916. http://dx.doi.org/10.1038/ni1001-907.
    • (2001) Nat. Immunol , vol.2 , pp. 907-916
    • Bogdan, C.1
  • 16
    • 77954917130 scopus 로고    scopus 로고
    • Nonconventional initiation complex assembly by STAT and NFkappaB transcription factors regulates nitric oxide synthase expression
    • Farlik M, Reutterer B, Schindler C, Greten F, Vogl C, Muller M, Decker T. 2010. Nonconventional initiation complex assembly by STAT and NFkappaB transcription factors regulates nitric oxide synthase expression. Immunity 33:25-34. http://dx.doi.org/10.1016/j.immuni.2010.07.001.
    • (2010) Immunity , vol.33 , pp. 25-34
    • Farlik, M.1    Reutterer, B.2    Schindler, C.3    Greten, F.4    Vogl, C.5    Muller, M.6    Decker, T.7
  • 18
    • 0030896666 scopus 로고    scopus 로고
    • Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis
    • Fehr T, Schoedon G, Odermatt B, Holtschke T, Schneemann M, Bachmann MF, Mak TW, Horak I, Zinkernagel RM. 1997. Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis. J. Exp. Med. 185:921-931. http://dx.doi.org/10.1084 /jem.185.5.921.
    • (1997) J. Exp. Med , vol.185 , pp. 921-931
    • Fehr, T.1    Schoedon, G.2    Odermatt, B.3    Holtschke, T.4    Schneemann, M.5    Bachmann, M.F.6    Mak, T.W.7    Horak, I.8    Zinkernagel, R.M.9
  • 19
    • 52749097161 scopus 로고    scopus 로고
    • Novel functions of type I interferons revealed by infection studies with Listeria monocytogenes
    • Stockinger S, Decker T. 2008. Novel functions of type I interferons revealed by infection studies with Listeria monocytogenes. Immunobiology 213:889-897. http://dx.doi.org/10.1016/j.imbio.2008.07.020.
    • (2008) Immunobiology , vol.213 , pp. 889-897
    • Stockinger, S.1    Decker, T.2
  • 20
    • 84861447117 scopus 로고    scopus 로고
    • Nitric oxide increases susceptibility of Toll-like receptor-activated macrophages to spreading Listeria monocytogenes
    • Cole C, Thomas S, Filak H, Henson PM, Lenz LL. 2012. Nitric oxide increases susceptibility of Toll-like receptor-activated macrophages to spreading Listeria monocytogenes. Immunity 36:807-820. http://dx.doi.org/10.1016/j.immuni.2012.03.011.
    • (2012) Immunity , vol.36 , pp. 807-820
    • Cole, C.1    Thomas, S.2    Filak, H.3    Henson, P.M.4    Lenz, L.L.5
  • 21
    • 84857052421 scopus 로고    scopus 로고
    • Transcriptional regulation in the innate immune system
    • Smale ST. 2012. Transcriptional regulation in the innate immune system. Curr. Opin. Immunol. 24:51-57. http://dx.doi.org/10.1016/j.coi.2011.12.008.
    • (2012) Curr. Opin. Immunol , vol.24 , pp. 51-57
    • Smale, S.T.1
  • 22
    • 84871699564 scopus 로고    scopus 로고
    • Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
    • Adelman K, Lis JT. 2012. Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans. Nat. Rev. Genet. 13:720-731. http: //dx.doi.org/10.1038/nrg3293.
    • (2012) Nat. Rev. Genet , vol.13 , pp. 720-731
    • Adelman, K.1    Lis, J.T.2
  • 23
    • 78650566210 scopus 로고    scopus 로고
    • Pol II waiting in the starting gates: regulating the transition from transcription initiation into productive elonga-tion
    • Nechaev S, Adelman K. 2011. Pol II waiting in the starting gates: regulating the transition from transcription initiation into productive elonga-tion. Biochim. Biophys. Acta 1809:34-45. http://dx.doi.org/10.1016/j.bbagrm.2010.11.001.
    • (2011) Biochim. Biophys. Acta , vol.1809 , pp. 34-45
    • Nechaev, S.1    Adelman, K.2
  • 24
    • 70349443224 scopus 로고    scopus 로고
    • Transcriptional control of the inflammatory response
    • Medzhitov R, Horng T. 2009. Transcriptional control of the inflammatory response. Nat. Rev. Immunol. 9:692-703. http://dx.doi.org/10.1038 /nri2634.
    • (2009) Nat. Rev. Immunol , vol.9 , pp. 692-703
    • Medzhitov, R.1    Horng, T.2
  • 25
    • 44149124228 scopus 로고    scopus 로고
    • Cracking the RNA polymerase II CTD code
    • Egloff S, Murphy S. 2008. Cracking the RNA polymerase II CTD code. Trends Genet. 24:280-288. http://dx.doi.org/10.1016/j.tig.2008.03.008.
    • (2008) Trends Genet , vol.24 , pp. 280-288
    • Egloff, S.1    Murphy, S.2
  • 26
    • 0041806599 scopus 로고    scopus 로고
    • The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis
    • Dey A, Chitsaz F, Abbasi A, Misteli T, Ozato K. 2003. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proc. Natl. Acad. Sci. U. S. A. 100:8758-8763. http://dx.doi.org/10.1073/pnas.1433065100.
    • (2003) Proc. Natl. Acad. Sci. U. S. A , vol.100 , pp. 8758-8763
    • Dey, A.1    Chitsaz, F.2    Abbasi, A.3    Misteli, T.4    Ozato, K.5
  • 27
    • 23744467035 scopus 로고    scopus 로고
    • Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4
    • Yang Z, Yik JHN, Chen R, He N, Jang MK, Ozato K, Zhou Q. 2005. Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Mol. Cell 19:535-545. http://dx.doi.org /10.1016/j.molcel.2005.06.029.
    • (2005) Mol. Cell , vol.19 , pp. 535-545
    • Yang, Z.1    Yik, J.H.N.2    Chen, R.3    He, N.4    Jang, M.K.5    Ozato, K.6    Zhou, Q.7
  • 28
    • 23744514308 scopus 로고    scopus 로고
    • The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulatesRNApolymerase II-dependent transcription
    • Jang MK, Mochizuki K, Zhou M, Jeong H-S, Brady JN, Ozato K. 2005. The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulatesRNApolymerase II-dependent transcription. Mol. Cell 19:523-534. http://dx.doi.org/10.1016/j.molcel.2005.06.027.
    • (2005) Mol. Cell , vol.19 , pp. 523-534
    • Jang, M.K.1    Mochizuki, K.2    Zhou, M.3    Jeong, H.-S.4    Brady, J.N.5    Ozato, K.6
  • 29
    • 34250357662 scopus 로고    scopus 로고
    • The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation
    • Wu S-Y, Chiang C-M. 2007. The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation. J. Biol. Chem. 282: 13141-13145. http://dx.doi.org/10.1074/jbc.R700001200.
    • (2007) J. Biol. Chem. , vol.282 , pp. 13141-13145
    • Wu, S.-Y.1    Chiang, C.-M.2
  • 30
    • 35348816030 scopus 로고    scopus 로고
    • Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
    • Bisgrove DA, Mahmoudi T, Henklein P, Verdin E. 2007. Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription. Proc. Natl. Acad. Sci. U. S. A. 104:13690-13695. http://dx.doi.org/10.1073/pnas.0705053104.
    • (2007) Proc. Natl. Acad. Sci. U. S. A , vol.104 , pp. 13690-13695
    • Bisgrove, D.A.1    Mahmoudi, T.2    Henklein, P.3    Verdin, E.4
  • 31
    • 67649648237 scopus 로고    scopus 로고
    • Control of inducible gene expression by signal-dependent transcriptional elongation
    • Hargreaves DC, Horng T, Medzhitov R. 2009. Control of inducible gene expression by signal-dependent transcriptional elongation. Cell 138:129- 145. http://dx.doi.org/10.1016/j.cell.2009.05.047.
    • (2009) Cell , vol.138 , pp. 129-145
    • Hargreaves, D.C.1    Horng, T.2    Medzhitov, R.3
  • 32
    • 1642564551 scopus 로고    scopus 로고
    • Selective recognition of acetylated histones by bromodomain proteins visualized in living cells
    • Kanno T, Kanno Y, Siegel RM, Jang MK, Lenardo MJ, Ozato K. 2004. Selective recognition of acetylated histones by bromodomain proteins visualized in living cells. Mol. Cell 13:33-43. http://dx.doi.org/10.1016 /S1097-2765(03)00482-9.
    • (2004) Mol. Cell , vol.13 , pp. 33-43
    • Kanno, T.1    Kanno, Y.2    Siegel, R.M.3    Jang, M.K.4    Lenardo, M.J.5    Ozato, K.6
  • 33
    • 41549115095 scopus 로고    scopus 로고
    • The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
    • LeRoy G, Rickards B, Flint SJ. 2008. The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription. Mol. Cell 30: 51-60. http://dx.doi.org/10.1016/j.molcel.2008.01.018.
    • (2008) Mol. Cell , vol.30 , pp. 51-60
    • LeRoy, G.1    Rickards, B.2    Flint, S.J.3
  • 34
    • 0033876160 scopus 로고    scopus 로고
    • RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F
    • Denis GV, Vaziri C, Guo N, Faller DV. 2000. RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F. Cell Growth Differ. 11:417-424.
    • (2000) Cell Growth Differ , vol.11 , pp. 417-424
    • Denis, G.V.1    Vaziri, C.2    Guo, N.3    Faller, D.V.4
  • 35
    • 34547621585 scopus 로고    scopus 로고
    • Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis
    • Wu F, Dassopoulos T, Cope L, Maitra A, Brant SR, Harris ML, Bayless TM, Parmigiani G, Chakravarti S. 2007. Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis. Inflamm. Bowel Dis. 13:807-821. http://dx.doi.org/10.1002/ibd.20110.
    • (2007) Inflamm. Bowel Dis , vol.13 , pp. 807-821
    • Wu, F.1    Dassopoulos, T.2    Cope, L.3    Maitra, A.4    Brant, S.R.5    Harris, M.L.6    Bayless, T.M.7    Parmigiani, G.8    Chakravarti, S.9
  • 36
    • 61749088806 scopus 로고    scopus 로고
    • Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA
    • Huang B, Yang X-D, Zhou M-M, Ozato K, Chen L-F. 2009. Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA. Mol. Cell. Biol. 29:1375-1387. http://dx.doi.org/10.1128 /MCB.01365-08.
    • (2009) Mol. Cell. Biol , vol.29 , pp. 1375-1387
    • Huang, B.1    Yang, X.-D.2    Zhou, M.-M.3    Ozato, K.4    Chen, L.-F.5
  • 38
    • 0036170183 scopus 로고    scopus 로고
    • IFN- stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff
    • Paulson M, Press C, Smith E, Tanese N, Levy DE. 2002. IFN-stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff. Nat. Cell Biol. 4:140-147. http://dx.doi.org/10.1038/ncb747.
    • (2002) Nat. Cell Biol , vol.4 , pp. 140-147
    • Paulson, M.1    Press, C.2    Smith, E.3    Tanese, N.4    Levy, D.E.5
  • 39
    • 84930583600 scopus 로고    scopus 로고
    • How Stats interact with the molecular machinery of transcriptional activation
    • Decker T, M̈ ullerM(ed), Jak-Stat signaling: from basics to disease. Springer, Vienna, Austria
    • Jamieson AM, Farlik M, Decker T. 2012. How Stats interact with the molecular machinery of transcriptional activation, p 65-89. In Decker T, M̈ ullerM(ed), Jak-Stat signaling: from basics to disease. Springer, Vienna, Austria.
    • (2012) , pp. 65-89
    • Jamieson, A.M.1    Farlik, M.2    Decker, T.3
  • 41
    • 84873256270 scopus 로고    scopus 로고
    • BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses
    • Belkina AC, Nikolajczyk BS, Denis GV. 2013. BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses. J. Immunol. 190: 3670-3678. http://dx.doi.org/10.4049/jimmunol.1202838.
    • (2013) J. Immunol. , vol.190 , pp. 3670-3678
    • Belkina, A.C.1    Nikolajczyk, B.S.2    Denis, G.V.3
  • 42
    • 84878966650 scopus 로고    scopus 로고
    • BRD4 coordinates recruitment of pause-release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon stimulated genes
    • Patel MC, Debrosse M, Smith M, Dey A, Huynh W, Sarai N, Heightman TD, Tamura T, Ozato K. 2013. BRD4 coordinates recruitment of pause-release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon stimulated genes. Mol. Cell. Biol. 33:2497-2507. http://dx.doi.org/10.1128/MCB.01180-12.
    • (2013) Mol. Cell. Biol , vol.33 , pp. 2497-2507
    • Patel, M.C.1    Debrosse, M.2    Smith, M.3    Dey, A.4    Huynh, W.5    Sarai, N.6    Heightman, T.D.7    Tamura, T.8    Ozato, K.9
  • 43
    • 84878573103 scopus 로고    scopus 로고
    • CDK9- dependent transcriptional elongation in the innate ISG response to RSV infection in airway epithelial cells
    • Tian B, Zhao Y, Kalita M, Edeh CB, Paessler S, Casola A, Teng MN, Garofalo RP, Brasier AR. 2013. CDK9-dependent transcriptional elongation in the innate ISG response to RSV infection in airway epithelial cells. J. Virol. 87:7075-7092. http://dx.doi.org/10.1128/JVI.03399-12.
    • (2013) J. Virol , vol.87 , pp. 7075-7092
    • Tian, B.1    Zhao, Y.2    Kalita, M.3    Edeh, C.B.4    Paessler, S.5    Casola, A.6    Teng, M.N.7    Garofalo, R.P.8    Brasier, A.R.9
  • 45
    • 0021955570 scopus 로고
    • In vitro natural cell-mediated cytotoxicity against Candida albicans: macrophage precursors as effector cells
    • Baccarini M, Bistoni F, Lohmann Matthes ML. 1985. In vitro natural cell-mediated cytotoxicity against Candida albicans: macrophage precursors as effector cells. J. Immunol. 134:2658-2665.
    • (1985) J. Immunol. , vol.134 , pp. 2658-2665
    • Baccarini, M.1    Bistoni, F.2    Lohmann Matthes, M.L.3
  • 47
    • 84877317891 scopus 로고    scopus 로고
    • Cross-platform microarray meta-analysis for the mouse jejunum selects novel reference genes with highly uniform levels of expression
    • Meyer FRL, Grausgruber H, Binter C, Mair GE, Guelly C, Vogl C, Steinborn R. 2013. Cross-platform microarray meta-analysis for the mouse jejunum selects novel reference genes with highly uniform levels of expression. PLoS One 8:e63125. http://dx.doi.org/10.1371/journal.pone.0063125.
    • (2013) PLoS One , vol.8
    • Meyer, F.R.L.1    Grausgruber, H.2    Binter, C.3    Mair, G.E.4    Guelly, C.5    Vogl, C.6    Steinborn, R.7
  • 48
    • 78651312134 scopus 로고    scopus 로고
    • Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
    • Zuber J, McJunkin K, Fellmann C, Dow LE, Taylor MJ, Hannon GJ, Lowe SW. 2011. Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi. Nat. Biotechnol. 29:79-83 http://dx.doi.org/10.1038/nbt.1720.
    • (2011) Nat. Biotechnol. , vol.29 , pp. 79-83
    • Zuber, J.1    McJunkin, K.2    Fellmann, C.3    Dow, L.E.4    Taylor, M.J.5    Hannon, G.J.6    Lowe, S.W.7
  • 49
    • 18844392836 scopus 로고    scopus 로고
    • Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
    • Hochedlinger K, Yamada Y, Beard C, Jaenisch R. 2005. Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 121:465-477. http://dx.doi.org/10.1016/j.cell.2005.02.018.
    • (2005) Cell , vol.121 , pp. 465-477
    • Hochedlinger, K.1    Yamada, Y.2    Beard, C.3    Jaenisch, R.4
  • 50
    • 0037625155 scopus 로고    scopus 로고
    • TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection
    • Serbina NV, Salazar-Mather TP, Biron CA, Kuziel WA, Pamer EG. 2003. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 19:59-70. http://dx.doi.org/10.1016/S1074-7613(03)00171-7.
    • (2003) Immunity , vol.19 , pp. 59-70
    • Serbina, N.V.1    Salazar-Mather, T.P.2    Biron, C.A.3    Kuziel, W.A.4    Pamer, E.G.5
  • 52
    • 2342522110 scopus 로고    scopus 로고
    • Shaping the nuclear action of NF-kappaB
    • Chen LF, Greene WC. 2004. Shaping the nuclear action of NF-kappaB. Nat. Rev. Mol. Cell Biol. 5:392-401. http://dx.doi.org/10.1038/nrm1368.
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 392-401
    • Chen, L.F.1    Greene, W.C.2
  • 53
    • 20744449274 scopus 로고    scopus 로고
    • Blockade of histone deacetylase inhibitor-induced RelA/p65 acetylation and NF-kappaB activation potentiates apoptosis in leukemia cells through a process mediated by oxidative damage, XIAP downregulation, and c-Jun N-terminal kinase 1 activation
    • Dai Y, Rahmani M, Dent Grant PS. 2005. Blockade of histone deacetylase inhibitor-induced RelA/p65 acetylation and NF-kappaB activation potentiates apoptosis in leukemia cells through a process mediated by oxidative damage, XIAP downregulation, and c-Jun N-terminal kinase 1 activation. Mol. Cell. Biol. 25:5429-5444. http://dx.doi.org/10.1128/MCB.25.13.5429-5444.2005.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 5429-5444
    • Dai, Y.1    Rahmani, M.2    Dent Grant, P.S.3
  • 54
    • 3242719545 scopus 로고    scopus 로고
    • Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
    • Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW. 2004. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23:2369-2380. http://dx.doi.org/10.1038/sj.emboj.7600244.
    • (2004) EMBO J , vol.23 , pp. 2369-2380
    • Yeung, F.1    Hoberg, J.E.2    Ramsey, C.S.3    Keller, M.D.4    Jones, D.R.5    Frye, R.A.6    Mayo, M.W.7
  • 55
    • 84880721384 scopus 로고    scopus 로고
    • Menin: a scaffold protein that controls gene expression and cell signaling
    • Matkar S, Thiel A, Hua X. 2013. Menin: a scaffold protein that controls gene expression and cell signaling. Trends Biochem. Sci. 38:394-402. http://dx.doi.org/10.1016/j.tibs.2013.05.005.
    • (2013) Trends Biochem. Sci , vol.38 , pp. 394-402
    • Matkar, S.1    Thiel, A.2    Hua, X.3
  • 56
    • 80655146232 scopus 로고    scopus 로고
    • RelA Ser276 phosphorylation-coupled Lys310 acetylation controls transcriptional elongation of inflammatory cytokines in respiratory syncytial virus infection
    • Brasier AR, Tian B, Jamaluddin M, Kalita MK, Garofalo RP, Lu M. 2011. RelA Ser276 phosphorylation-coupled Lys310 acetylation controls transcriptional elongation of inflammatory cytokines in respiratory syncytial virus infection. J. Virol. 85:11752-11769. http://dx.doi.org/10.1128 /JVI.05360-11.
    • (2011) J. Virol , vol.85 , pp. 11752-11769
    • Brasier, A.R.1    Tian, B.2    Jamaluddin, M.3    Kalita, M.K.4    Garofalo, R.P.5    Lu, M.6
  • 57
    • 33746403681 scopus 로고    scopus 로고
    • Controlling the elongation phase of transcription with P-TEFb
    • Peterlin BMB, Price DHD. 2006. Controlling the elongation phase of transcription with P-TEFb. Mol. Cell 23:297-305. http://dx.doi.org/10.1016/j.molcel.2006.06.014.
    • (2006) Mol. Cell , vol.23 , pp. 297-305
    • Peterlin, B.M.B.1    Price, D.H.D.2
  • 59
    • 0026074368 scopus 로고
    • In vivo protective effect of tumour necrosis factor alpha against experimental infection with herpes simplex virus type 1
    • Rossol-Voth R, Rossol S, Schütt KH, Corridori S, de Cian W, Falke D. 1991. In vivo protective effect of tumour necrosis factor alpha against experimental infection with herpes simplex virus type 1. J. Gen. Virol. 72:143-147. http://dx.doi.org/10.1099/0022-1317-72-1-143.
    • (1991) J. Gen. Virol , vol.72 , pp. 143-147
    • Rossol-Voth, R.1    Rossol, S.2    Schütt, K.H.3    Corridori, S.4    de Cian, W.5    Falke, D.6
  • 61
    • 84878756188 scopus 로고    scopus 로고
    • Role of tissue protection in lethal respiratory viralbacterial coinfection
    • Jamieson AM, Pasman L, Yu S, Gamradt P, Homer RJ, Decker T, Medzhitov R. 2013. Role of tissue protection in lethal respiratory viralbacterial coinfection. Science 340:1230-1234. http://dx.doi.org/10.1126 /science.1233632.
    • (2013) Science , vol.340 , pp. 1230-1234
    • Jamieson, A.M.1    Pasman, L.2    Yu, S.3    Gamradt, P.4    Homer, R.J.5    Decker, T.6    Medzhitov, R.7
  • 62
    • 33750253585 scopus 로고    scopus 로고
    • Enhanced antiviral antibody secretion and attenuated immunopathology during influenza virus infection in nitric oxide synthase-2-deficient mice
    • Jayasekera JP, Vinuesa CG, Karupiah G, King NJC. 2006. Enhanced antiviral antibody secretion and attenuated immunopathology during influenza virus infection in nitric oxide synthase-2-deficient mice. J. Gen. Virol. 87:3361-3371. http://dx.doi.org/10.1099/vir.0.82131-0.
    • (2006) J. Gen. Virol , vol.87 , pp. 3361-3371
    • Jayasekera, J.P.1    Vinuesa, C.G.2    Karupiah, G.3    King, N.J.C.4
  • 63
    • 3242664636 scopus 로고    scopus 로고
    • Recognition of commensal microflora by Toll-like receptors is required for intestinalhomeostasis
    • Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F. 2004. Recognition of commensal microflora by Toll-like receptors is required for intestinalhomeostasis. Cell 118:229-241. http://dx.doi.org/10.1016/j.cell.2004.07.002.
    • (2004) Cell , vol.118 , pp. 229-241
    • Rakoff-Nahoum, S.1    Paglino, J.2    Eslami-Varzaneh, F.3
  • 64
    • 84857444508 scopus 로고    scopus 로고
    • B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage
    • Kirkland D, Benson A, Mirpuri J, Pifer R, Hou B, DeFranco AL, Yarovinsky F. 2012. B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage. Immunity 36:228-238. http://dx.doi.org/10.1016/j.immuni.2011.11.019.
    • (2012) Immunity , vol.36 , pp. 228-238
    • Kirkland, D.1    Benson, A.2    Mirpuri, J.3    Pifer, R.4    Hou, B.5    DeFranco, A.L.6    Yarovinsky, F.7
  • 66
    • 79954552505 scopus 로고    scopus 로고
    • The super elongation complex (SEC) and MLL in development and disease
    • Smith E, Lin C, Shilatifard A. 2011. The super elongation complex (SEC) and MLL in development and disease. Genes Dev. 25:661-672. http://dx.doi.org/10.1101/gad.2015411.
    • (2011) Genes Dev , vol.25 , pp. 661-672
    • Smith, E.1    Lin, C.2    Shilatifard, A.3
  • 67
    • 77958111633 scopus 로고    scopus 로고
    • The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
    • Malik S, Roeder RG. 2010. The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nat. Rev. Genet. 11: 761-772. http://dx.doi.org/10.1038/nrg2901.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 761-772
    • Malik, S.1    Roeder, R.G.2
  • 68
    • 84872376792 scopus 로고    scopus 로고
    • The Mediator complex and transcription elongation
    • Conaway RC, Conaway JW. 2013. The Mediator complex and transcription elongation. Biochim. Biophys. Acta 1829:69-75. http://dx.doi.org/10.1016/j.bbagrm.2012.08.017.
    • (2013) Biochim. Biophys. Acta , vol.1829 , pp. 69-75
    • Conaway, R.C.1    Conaway, J.W.2
  • 69
    • 76349090199 scopus 로고    scopus 로고
    • CDK8 is a positive regulator of transcriptional elongation within the serum response network
    • Donner AJ, Ebmeier CC, Taatjes DJ, Espinosa JM. 2010. CDK8 is a positive regulator of transcriptional elongation within the serum response network. Nat. Struct. Mol. Biol. 17:194-201. http://dx.doi.org/10.1038 /nsmb.1752.
    • (2010) Nat. Struct. Mol. Biol , vol.17 , pp. 194-201
    • Donner, A.J.1    Ebmeier, C.C.2    Taatjes, D.J.3    Espinosa, J.M.4
  • 71
    • 84869054253 scopus 로고    scopus 로고
    • Cross-talk among RNA polymerase II kinases modulates C-terminal domain phosphorylation
    • Devaiah BN, Singer DS. 2012. Cross-talk among RNA polymerase II kinases modulates C-terminal domain phosphorylation. J. Biol. Chem. 287:38755-38766. http://dx.doi.org/10.1074/jbc.M112.412015.
    • (2012) J. Biol. Chem , vol.287 , pp. 38755-38766
    • Devaiah, B.N.1    Singer, D.S.2
  • 72
    • 0029007193 scopus 로고
    • Interleukin-6-deficient mice are highly susceptible to Listeria monocytogenes infection: correlation with inefficient neutrophilia
    • Dalrymple SA, Lucian LA, Slattery R, McNeil T, Aud DM, Fuchino S, Lee F, Murray R. 1995. Interleukin-6-deficient mice are highly susceptible to Listeria monocytogenes infection: correlation with inefficient neutrophilia. Infect. Immun. 63:2262-2268.
    • (1995) Infect. Immun. , vol.63 , pp. 2262-2268
    • Dalrymple, S.A.1    Lucian, L.A.2    Slattery, R.3    McNeil, T.4    Aud, D.M.5    Fuchino, S.6    Lee, F.7    Murray, R.8
  • 75
    • 33645116785 scopus 로고    scopus 로고
    • NF- kappa B activation as a pathological mechanism of septic shock and inflammation
    • Liu SF, Malik AB. 2006. NF-kappa B activation as a pathological mechanism of septic shock and inflammation. Am. J. Physiol. Lung Cell. Mol. Physiol. 290:L622-L645. http://dx.doi.org/10.1152/ajplung.00477.2005.
    • (2006) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.290
    • Liu, S.F.1    Malik, A.B.2


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