-
2
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki A, Medzhitov R. 2010. Regulation of adaptive immunity by the innate immune system. Science 327:291-295. http://dx.doi.org/10.1126 /science.1183021.
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
3
-
-
0036327382
-
The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity
-
Portnoy DA, Auerbuch V, Glomski IJ. 2002. The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity. J. Cell Biol. 158:409-414. http://dx.doi.org/10 .1083/jcb.200205009.
-
(2002)
J. Cell Biol
, vol.158
, pp. 409-414
-
-
Portnoy, D.A.1
Auerbuch, V.2
Glomski, I.J.3
-
4
-
-
33646844623
-
Listeria monocytogenes: a multifaceted model
-
Hamon M, Bierne H, Cossart P. 2006. Listeria monocytogenes: a multifaceted model. Nat. Rev. Microbiol. 4:423-434. http://dx.doi.org/10.1038/nrmicro1413.
-
(2006)
Nat. Rev. Microbiol
, vol.4
, pp. 423-434
-
-
Hamon, M.1
Bierne, H.2
Cossart, P.3
-
5
-
-
0036785630
-
Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice
-
Seki E, Tsutsui H, Tsuji NM, Hayashi N, Adachi K, Nakano H, Futatsugi-Yumikura S, Takeuchi O, Hoshino K, Akira S, Fujimoto J, Nakanishi K. 2002. Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice. J. Immunol. 169:3863-3868.
-
(2002)
J. Immunol.
, vol.169
, pp. 3863-3868
-
-
Seki, E.1
Tsutsui, H.2
Tsuji, N.M.3
Hayashi, N.4
Adachi, K.5
Nakano, H.6
Futatsugi-Yumikura, S.7
Takeuchi, O.8
Hoshino, K.9
Akira, S.10
Fujimoto, J.11
Nakanishi, K.12
-
6
-
-
67349187318
-
Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells
-
Mancuso G, Gambuzza M, Midiri A, Biondo C, Papasergi S, Akira S, Teti G, Beninati C. 2009. Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells. Nat. Immunol. 10:587-594. http://dx.doi.org/10.1038/ni.1733.
-
(2009)
Nat. Immunol
, vol.10
, pp. 587-594
-
-
Mancuso, G.1
Gambuzza, M.2
Midiri, A.3
Biondo, C.4
Papasergi, S.5
Akira, S.6
Teti, G.7
Beninati, C.8
-
7
-
-
77954070545
-
c- di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response
-
Woodward JJ, Iavarone AT, Portnoy DA. 2010. c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 328:1703-1705. http://dx.doi.org/10.1126/science.1189801.
-
(2010)
Science
, vol.328
, pp. 1703-1705
-
-
Woodward, J.J.1
Iavarone, A.T.2
Portnoy, D.A.3
-
8
-
-
79251506939
-
The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides
-
Sauer J-D, Sotelo-Troha K, von Moltke, J, Monroe KM, Rae CS, Brubaker SW, Hyodo M, Hayakawa Y, Woodward JJ, Portnoy DA, Vance RE. 2011. The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infect. Immun. 79:688-694. http://dx.doi.org/10.1128/IAI.00999-10.
-
(2011)
Infect. Immun
, vol.79
, pp. 688-694
-
-
Sauer, J.-D.1
Sotelo-Troha, K.2
von Moltke, J.3
Monroe, K.M.4
Rae, C.S.5
Brubaker, S.W.6
Hyodo, M.7
Hayakawa, Y.8
Woodward, J.J.9
Portnoy, D.A.10
Vance, R.E.11
-
9
-
-
0037108761
-
Innate recognition of bacteria by a macrophage cytosolic surveillance pathway
-
O'Riordan M, Yi CH, Gonzales R, Lee KD, Portnoy DA. 2002. Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc. Natl. Acad. Sci. U. S. A. 99:13861-13866. http://dx.doi.org/10.1073 /pnas.202476699.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A
, vol.99
, pp. 13861-13866
-
-
O'Riordan, M.1
Yi, C.H.2
Gonzales, R.3
Lee, K.D.4
Portnoy, D.A.5
-
10
-
-
0036884550
-
Production of type I IFN sensitizes macrophages to cell death induced by Listeria monocytogenes
-
Stockinger S, Materna T, Stoiber D, Bayr L, Steinborn R, Kolbe T, Unger H, Chakraborty T, Levy DE, Muller M, Decker T. 2002. Production of type I IFN sensitizes macrophages to cell death induced by Listeria monocytogenes. J. Immunol. 169:6522-6529.
-
(2002)
J. Immunol.
, vol.169
, pp. 6522-6529
-
-
Stockinger, S.1
Materna, T.2
Stoiber, D.3
Bayr, L.4
Steinborn, R.5
Kolbe, T.6
Unger, H.7
Chakraborty, T.8
Levy, D.E.9
Muller, M.10
Decker, T.11
-
11
-
-
0036731485
-
Stats: transcriptional control and biological impact
-
Levy DE, Darnell JE, Jr. 2002. Stats: transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 3:651-662. http://dx.doi.org/10.1038 /nrm909.
-
(2002)
Nat. Rev. Mol. Cell Biol
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell Jr., J.E.2
-
12
-
-
0036222241
-
TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages
-
Toshchakov V, Jones BW, Perera PY, Thomas K, Cody MJ, Zhang S, Williams BR, Major J, Hamilton TA, Fenton MJ, Vogel SN. 2002. TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages. Nat. Immunol. 3:392-398. http://dx.doi.org/10.1038/ni774.
-
(2002)
Nat. Immunol
, vol.3
, pp. 392-398
-
-
Toshchakov, V.1
Jones, B.W.2
Perera, P.Y.3
Thomas, K.4
Cody, M.J.5
Zhang, S.6
Williams, B.R.7
Major, J.8
Hamilton, T.A.9
Fenton, M.J.10
Vogel, S.N.11
-
13
-
-
3843092622
-
A specific gene expression program triggered by Gram-positive bacteria in the cytosol
-
McCaffrey RL, Fawcett P, O'Riordan M, Lee KD, Havell EA, Brown PO, Portnoy DA. 2004. A specific gene expression program triggered by Gram-positive bacteria in the cytosol. Proc. Natl. Acad. Sci. U. S. A. 101: 11386-11391. http://dx.doi.org/10.1073/pnas.0403215101.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 11386-11391
-
-
McCaffrey, R.L.1
Fawcett, P.2
O'Riordan, M.3
Lee, K.D.4
Havell, E.A.5
Brown, P.O.6
Portnoy, D.A.7
-
14
-
-
0001378811
-
Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharideinduced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene
-
Gao JJ, Filla MB, Fultz MJ, Vogel SN, Russell SW, Murphy WJ. 1998. Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharideinduced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene. J. Immunol. 161:4803-4810.
-
(1998)
J. Immunol.
, vol.161
, pp. 4803-4810
-
-
Gao, J.J.1
Filla, M.B.2
Fultz, M.J.3
Vogel, S.N.4
Russell, S.W.5
Murphy, W.J.6
-
15
-
-
0034769118
-
Nitric oxide and the immune response
-
Bogdan C. 2001. Nitric oxide and the immune response. Nat. Immunol. 2:907-916. http://dx.doi.org/10.1038/ni1001-907.
-
(2001)
Nat. Immunol
, vol.2
, pp. 907-916
-
-
Bogdan, C.1
-
16
-
-
77954917130
-
Nonconventional initiation complex assembly by STAT and NFkappaB transcription factors regulates nitric oxide synthase expression
-
Farlik M, Reutterer B, Schindler C, Greten F, Vogl C, Muller M, Decker T. 2010. Nonconventional initiation complex assembly by STAT and NFkappaB transcription factors regulates nitric oxide synthase expression. Immunity 33:25-34. http://dx.doi.org/10.1016/j.immuni.2010.07.001.
-
(2010)
Immunity
, vol.33
, pp. 25-34
-
-
Farlik, M.1
Reutterer, B.2
Schindler, C.3
Greten, F.4
Vogl, C.5
Muller, M.6
Decker, T.7
-
17
-
-
0028999596
-
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
-
(Erratum, 81 following 1170. )
-
MacMicking JD, Nathan C, Hom G, Chartrain N, Fletcher DS, Trumbauer M, Stevens K, Xie QW, Sokol K, Hutchinson N, Chen H, Mudget JS. 1995. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 81:641-650. (Erratum, 81:following 1170.)
-
(1995)
Cell
, vol.81
, pp. 641-650
-
-
MacMicking, J.D.1
Nathan, C.2
Hom, G.3
Chartrain, N.4
Fletcher, D.S.5
Trumbauer, M.6
Stevens, K.7
Xie, Q.W.8
Sokol, K.9
Hutchinson, N.10
Chen, H.11
Mudget, J.S.12
-
18
-
-
0030896666
-
Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis
-
Fehr T, Schoedon G, Odermatt B, Holtschke T, Schneemann M, Bachmann MF, Mak TW, Horak I, Zinkernagel RM. 1997. Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis. J. Exp. Med. 185:921-931. http://dx.doi.org/10.1084 /jem.185.5.921.
-
(1997)
J. Exp. Med
, vol.185
, pp. 921-931
-
-
Fehr, T.1
Schoedon, G.2
Odermatt, B.3
Holtschke, T.4
Schneemann, M.5
Bachmann, M.F.6
Mak, T.W.7
Horak, I.8
Zinkernagel, R.M.9
-
19
-
-
52749097161
-
Novel functions of type I interferons revealed by infection studies with Listeria monocytogenes
-
Stockinger S, Decker T. 2008. Novel functions of type I interferons revealed by infection studies with Listeria monocytogenes. Immunobiology 213:889-897. http://dx.doi.org/10.1016/j.imbio.2008.07.020.
-
(2008)
Immunobiology
, vol.213
, pp. 889-897
-
-
Stockinger, S.1
Decker, T.2
-
20
-
-
84861447117
-
Nitric oxide increases susceptibility of Toll-like receptor-activated macrophages to spreading Listeria monocytogenes
-
Cole C, Thomas S, Filak H, Henson PM, Lenz LL. 2012. Nitric oxide increases susceptibility of Toll-like receptor-activated macrophages to spreading Listeria monocytogenes. Immunity 36:807-820. http://dx.doi.org/10.1016/j.immuni.2012.03.011.
-
(2012)
Immunity
, vol.36
, pp. 807-820
-
-
Cole, C.1
Thomas, S.2
Filak, H.3
Henson, P.M.4
Lenz, L.L.5
-
21
-
-
84857052421
-
Transcriptional regulation in the innate immune system
-
Smale ST. 2012. Transcriptional regulation in the innate immune system. Curr. Opin. Immunol. 24:51-57. http://dx.doi.org/10.1016/j.coi.2011.12.008.
-
(2012)
Curr. Opin. Immunol
, vol.24
, pp. 51-57
-
-
Smale, S.T.1
-
22
-
-
84871699564
-
Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
-
Adelman K, Lis JT. 2012. Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans. Nat. Rev. Genet. 13:720-731. http: //dx.doi.org/10.1038/nrg3293.
-
(2012)
Nat. Rev. Genet
, vol.13
, pp. 720-731
-
-
Adelman, K.1
Lis, J.T.2
-
23
-
-
78650566210
-
Pol II waiting in the starting gates: regulating the transition from transcription initiation into productive elonga-tion
-
Nechaev S, Adelman K. 2011. Pol II waiting in the starting gates: regulating the transition from transcription initiation into productive elonga-tion. Biochim. Biophys. Acta 1809:34-45. http://dx.doi.org/10.1016/j.bbagrm.2010.11.001.
-
(2011)
Biochim. Biophys. Acta
, vol.1809
, pp. 34-45
-
-
Nechaev, S.1
Adelman, K.2
-
24
-
-
70349443224
-
Transcriptional control of the inflammatory response
-
Medzhitov R, Horng T. 2009. Transcriptional control of the inflammatory response. Nat. Rev. Immunol. 9:692-703. http://dx.doi.org/10.1038 /nri2634.
-
(2009)
Nat. Rev. Immunol
, vol.9
, pp. 692-703
-
-
Medzhitov, R.1
Horng, T.2
-
25
-
-
44149124228
-
Cracking the RNA polymerase II CTD code
-
Egloff S, Murphy S. 2008. Cracking the RNA polymerase II CTD code. Trends Genet. 24:280-288. http://dx.doi.org/10.1016/j.tig.2008.03.008.
-
(2008)
Trends Genet
, vol.24
, pp. 280-288
-
-
Egloff, S.1
Murphy, S.2
-
26
-
-
0041806599
-
The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis
-
Dey A, Chitsaz F, Abbasi A, Misteli T, Ozato K. 2003. The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proc. Natl. Acad. Sci. U. S. A. 100:8758-8763. http://dx.doi.org/10.1073/pnas.1433065100.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A
, vol.100
, pp. 8758-8763
-
-
Dey, A.1
Chitsaz, F.2
Abbasi, A.3
Misteli, T.4
Ozato, K.5
-
27
-
-
23744467035
-
Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4
-
Yang Z, Yik JHN, Chen R, He N, Jang MK, Ozato K, Zhou Q. 2005. Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4. Mol. Cell 19:535-545. http://dx.doi.org /10.1016/j.molcel.2005.06.029.
-
(2005)
Mol. Cell
, vol.19
, pp. 535-545
-
-
Yang, Z.1
Yik, J.H.N.2
Chen, R.3
He, N.4
Jang, M.K.5
Ozato, K.6
Zhou, Q.7
-
28
-
-
23744514308
-
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulatesRNApolymerase II-dependent transcription
-
Jang MK, Mochizuki K, Zhou M, Jeong H-S, Brady JN, Ozato K. 2005. The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulatesRNApolymerase II-dependent transcription. Mol. Cell 19:523-534. http://dx.doi.org/10.1016/j.molcel.2005.06.027.
-
(2005)
Mol. Cell
, vol.19
, pp. 523-534
-
-
Jang, M.K.1
Mochizuki, K.2
Zhou, M.3
Jeong, H.-S.4
Brady, J.N.5
Ozato, K.6
-
29
-
-
34250357662
-
The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation
-
Wu S-Y, Chiang C-M. 2007. The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation. J. Biol. Chem. 282: 13141-13145. http://dx.doi.org/10.1074/jbc.R700001200.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 13141-13145
-
-
Wu, S.-Y.1
Chiang, C.-M.2
-
30
-
-
35348816030
-
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
-
Bisgrove DA, Mahmoudi T, Henklein P, Verdin E. 2007. Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription. Proc. Natl. Acad. Sci. U. S. A. 104:13690-13695. http://dx.doi.org/10.1073/pnas.0705053104.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A
, vol.104
, pp. 13690-13695
-
-
Bisgrove, D.A.1
Mahmoudi, T.2
Henklein, P.3
Verdin, E.4
-
31
-
-
67649648237
-
Control of inducible gene expression by signal-dependent transcriptional elongation
-
Hargreaves DC, Horng T, Medzhitov R. 2009. Control of inducible gene expression by signal-dependent transcriptional elongation. Cell 138:129- 145. http://dx.doi.org/10.1016/j.cell.2009.05.047.
-
(2009)
Cell
, vol.138
, pp. 129-145
-
-
Hargreaves, D.C.1
Horng, T.2
Medzhitov, R.3
-
32
-
-
1642564551
-
Selective recognition of acetylated histones by bromodomain proteins visualized in living cells
-
Kanno T, Kanno Y, Siegel RM, Jang MK, Lenardo MJ, Ozato K. 2004. Selective recognition of acetylated histones by bromodomain proteins visualized in living cells. Mol. Cell 13:33-43. http://dx.doi.org/10.1016 /S1097-2765(03)00482-9.
-
(2004)
Mol. Cell
, vol.13
, pp. 33-43
-
-
Kanno, T.1
Kanno, Y.2
Siegel, R.M.3
Jang, M.K.4
Lenardo, M.J.5
Ozato, K.6
-
33
-
-
41549115095
-
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
-
LeRoy G, Rickards B, Flint SJ. 2008. The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription. Mol. Cell 30: 51-60. http://dx.doi.org/10.1016/j.molcel.2008.01.018.
-
(2008)
Mol. Cell
, vol.30
, pp. 51-60
-
-
LeRoy, G.1
Rickards, B.2
Flint, S.J.3
-
34
-
-
0033876160
-
RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F
-
Denis GV, Vaziri C, Guo N, Faller DV. 2000. RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F. Cell Growth Differ. 11:417-424.
-
(2000)
Cell Growth Differ
, vol.11
, pp. 417-424
-
-
Denis, G.V.1
Vaziri, C.2
Guo, N.3
Faller, D.V.4
-
35
-
-
34547621585
-
Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis
-
Wu F, Dassopoulos T, Cope L, Maitra A, Brant SR, Harris ML, Bayless TM, Parmigiani G, Chakravarti S. 2007. Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis. Inflamm. Bowel Dis. 13:807-821. http://dx.doi.org/10.1002/ibd.20110.
-
(2007)
Inflamm. Bowel Dis
, vol.13
, pp. 807-821
-
-
Wu, F.1
Dassopoulos, T.2
Cope, L.3
Maitra, A.4
Brant, S.R.5
Harris, M.L.6
Bayless, T.M.7
Parmigiani, G.8
Chakravarti, S.9
-
36
-
-
61749088806
-
Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA
-
Huang B, Yang X-D, Zhou M-M, Ozato K, Chen L-F. 2009. Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA. Mol. Cell. Biol. 29:1375-1387. http://dx.doi.org/10.1128 /MCB.01365-08.
-
(2009)
Mol. Cell. Biol
, vol.29
, pp. 1375-1387
-
-
Huang, B.1
Yang, X.-D.2
Zhou, M.-M.3
Ozato, K.4
Chen, L.-F.5
-
37
-
-
67649669255
-
A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling
-
Ramirez-Carrozzi VR, Braas D, Bhatt DM, Cheng CS, Hong C, Doty KR, Black JC, Hoffmann A, Carey M, Smale ST. 2009. A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell 138:114-128. http://dx.doi.org/10.1016/j.cell.2009.04.020.
-
(2009)
Cell
, vol.138
, pp. 114-128
-
-
Ramirez-Carrozzi, V.R.1
Braas, D.2
Bhatt, D.M.3
Cheng, C.S.4
Hong, C.5
Doty, K.R.6
Black, J.C.7
Hoffmann, A.8
Carey, M.9
Smale, S.T.10
-
38
-
-
0036170183
-
IFN- stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff
-
Paulson M, Press C, Smith E, Tanese N, Levy DE. 2002. IFN-stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff. Nat. Cell Biol. 4:140-147. http://dx.doi.org/10.1038/ncb747.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 140-147
-
-
Paulson, M.1
Press, C.2
Smith, E.3
Tanese, N.4
Levy, D.E.5
-
39
-
-
84930583600
-
How Stats interact with the molecular machinery of transcriptional activation
-
Decker T, M̈ ullerM(ed), Jak-Stat signaling: from basics to disease. Springer, Vienna, Austria
-
Jamieson AM, Farlik M, Decker T. 2012. How Stats interact with the molecular machinery of transcriptional activation, p 65-89. In Decker T, M̈ ullerM(ed), Jak-Stat signaling: from basics to disease. Springer, Vienna, Austria.
-
(2012)
, pp. 65-89
-
-
Jamieson, A.M.1
Farlik, M.2
Decker, T.3
-
40
-
-
78650806593
-
Suppression of inflammation by a synthetic histone mimic
-
Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, Chung C-W, Chandwani R, Marazzi I, Wilson P, Coste H, White J, Kirilovsky J, Rice CM, Lora JM, Prinjha RK, Lee K, Tarakhovsky A. 2010. Suppression of inflammation by a synthetic histone mimic. Nature 468:1119-1123. http: //dx.doi.org/10.1038/nature09589.
-
(2010)
Nature
, vol.468
, pp. 1119-1123
-
-
Nicodeme, E.1
Jeffrey, K.L.2
Schaefer, U.3
Beinke, S.4
Dewell, S.5
Chung, C.-W.6
Chandwani, R.7
Marazzi, I.8
Wilson, P.9
Coste, H.10
White, J.11
Kirilovsky, J.12
Rice, C.M.13
Lora, J.M.14
Prinjha, R.K.15
Lee, K.16
Tarakhovsky, A.17
-
41
-
-
84873256270
-
BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses
-
Belkina AC, Nikolajczyk BS, Denis GV. 2013. BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses. J. Immunol. 190: 3670-3678. http://dx.doi.org/10.4049/jimmunol.1202838.
-
(2013)
J. Immunol.
, vol.190
, pp. 3670-3678
-
-
Belkina, A.C.1
Nikolajczyk, B.S.2
Denis, G.V.3
-
42
-
-
84878966650
-
BRD4 coordinates recruitment of pause-release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon stimulated genes
-
Patel MC, Debrosse M, Smith M, Dey A, Huynh W, Sarai N, Heightman TD, Tamura T, Ozato K. 2013. BRD4 coordinates recruitment of pause-release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon stimulated genes. Mol. Cell. Biol. 33:2497-2507. http://dx.doi.org/10.1128/MCB.01180-12.
-
(2013)
Mol. Cell. Biol
, vol.33
, pp. 2497-2507
-
-
Patel, M.C.1
Debrosse, M.2
Smith, M.3
Dey, A.4
Huynh, W.5
Sarai, N.6
Heightman, T.D.7
Tamura, T.8
Ozato, K.9
-
43
-
-
84878573103
-
CDK9- dependent transcriptional elongation in the innate ISG response to RSV infection in airway epithelial cells
-
Tian B, Zhao Y, Kalita M, Edeh CB, Paessler S, Casola A, Teng MN, Garofalo RP, Brasier AR. 2013. CDK9-dependent transcriptional elongation in the innate ISG response to RSV infection in airway epithelial cells. J. Virol. 87:7075-7092. http://dx.doi.org/10.1128/JVI.03399-12.
-
(2013)
J. Virol
, vol.87
, pp. 7075-7092
-
-
Tian, B.1
Zhao, Y.2
Kalita, M.3
Edeh, C.B.4
Paessler, S.5
Casola, A.6
Teng, M.N.7
Garofalo, R.P.8
Brasier, A.R.9
-
44
-
-
78650847770
-
Selective inhibition of BET bromodomains
-
Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE. 2010. Selective inhibition of BET bromodomains. Nature 468:1067-1073. http://dx.doi.org/10.1038/nature09504.
-
(2010)
Nature
, vol.468
, pp. 1067-1073
-
-
Filippakopoulos, P.1
Qi, J.2
Picaud, S.3
Shen, Y.4
Smith, W.B.5
Fedorov, O.6
Morse, E.M.7
Keates, T.8
Hickman, T.T.9
Felletar, I.10
Philpott, M.11
Munro, S.12
McKeown, M.R.13
Wang, Y.14
Christie, A.L.15
West, N.16
Cameron, M.J.17
Schwartz, B.18
Heightman, T.D.19
La Thangue, N.20
French, C.A.21
Wiest, O.22
Kung, A.L.23
Knapp, S.24
Bradner, J.E.25
more..
-
45
-
-
0021955570
-
In vitro natural cell-mediated cytotoxicity against Candida albicans: macrophage precursors as effector cells
-
Baccarini M, Bistoni F, Lohmann Matthes ML. 1985. In vitro natural cell-mediated cytotoxicity against Candida albicans: macrophage precursors as effector cells. J. Immunol. 134:2658-2665.
-
(1985)
J. Immunol.
, vol.134
, pp. 2658-2665
-
-
Baccarini, M.1
Bistoni, F.2
Lohmann Matthes, M.L.3
-
46
-
-
10344252795
-
IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism
-
Stockinger S, Reutterer B, Schaljo B, Schellack C, Brunner S, Materna T, Yamamoto M, Akira S, Taniguchi T, Murray PJ, Muller M, Decker T. 2004. IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism. J. Immunol. 173:7416-7425.
-
(2004)
J. Immunol.
, vol.173
, pp. 7416-7425
-
-
Stockinger, S.1
Reutterer, B.2
Schaljo, B.3
Schellack, C.4
Brunner, S.5
Materna, T.6
Yamamoto, M.7
Akira, S.8
Taniguchi, T.9
Murray, P.J.10
Muller, M.11
Decker, T.12
-
47
-
-
84877317891
-
Cross-platform microarray meta-analysis for the mouse jejunum selects novel reference genes with highly uniform levels of expression
-
Meyer FRL, Grausgruber H, Binter C, Mair GE, Guelly C, Vogl C, Steinborn R. 2013. Cross-platform microarray meta-analysis for the mouse jejunum selects novel reference genes with highly uniform levels of expression. PLoS One 8:e63125. http://dx.doi.org/10.1371/journal.pone.0063125.
-
(2013)
PLoS One
, vol.8
-
-
Meyer, F.R.L.1
Grausgruber, H.2
Binter, C.3
Mair, G.E.4
Guelly, C.5
Vogl, C.6
Steinborn, R.7
-
48
-
-
78651312134
-
Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi
-
Zuber J, McJunkin K, Fellmann C, Dow LE, Taylor MJ, Hannon GJ, Lowe SW. 2011. Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi. Nat. Biotechnol. 29:79-83 http://dx.doi.org/10.1038/nbt.1720.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 79-83
-
-
Zuber, J.1
McJunkin, K.2
Fellmann, C.3
Dow, L.E.4
Taylor, M.J.5
Hannon, G.J.6
Lowe, S.W.7
-
49
-
-
18844392836
-
Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
-
Hochedlinger K, Yamada Y, Beard C, Jaenisch R. 2005. Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 121:465-477. http://dx.doi.org/10.1016/j.cell.2005.02.018.
-
(2005)
Cell
, vol.121
, pp. 465-477
-
-
Hochedlinger, K.1
Yamada, Y.2
Beard, C.3
Jaenisch, R.4
-
50
-
-
0037625155
-
TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection
-
Serbina NV, Salazar-Mather TP, Biron CA, Kuziel WA, Pamer EG. 2003. TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. Immunity 19:59-70. http://dx.doi.org/10.1016/S1074-7613(03)00171-7.
-
(2003)
Immunity
, vol.19
, pp. 59-70
-
-
Serbina, N.V.1
Salazar-Mather, T.P.2
Biron, C.A.3
Kuziel, W.A.4
Pamer, E.G.5
-
51
-
-
79251566745
-
Novel cross-talk within the IKK family controls innate immunity
-
Clark K, Peggie M, Plater L, Sorcek RJ, Young ERR, Madwed JB, Hough J, McIver EG, Cohen P. 2011. Novel cross-talk within the IKK family controls innate immunity. Biochem. J. 434:93-104. http://dx.doi.org/10.1042/BJ20101701.
-
(2011)
Biochem. J
, vol.434
, pp. 93-104
-
-
Clark, K.1
Peggie, M.2
Plater, L.3
Sorcek, R.J.4
Young, E.R.R.5
Madwed, J.B.6
Hough, J.7
McIver, E.G.8
Cohen, P.9
-
52
-
-
2342522110
-
Shaping the nuclear action of NF-kappaB
-
Chen LF, Greene WC. 2004. Shaping the nuclear action of NF-kappaB. Nat. Rev. Mol. Cell Biol. 5:392-401. http://dx.doi.org/10.1038/nrm1368.
-
(2004)
Nat. Rev. Mol. Cell Biol
, vol.5
, pp. 392-401
-
-
Chen, L.F.1
Greene, W.C.2
-
53
-
-
20744449274
-
Blockade of histone deacetylase inhibitor-induced RelA/p65 acetylation and NF-kappaB activation potentiates apoptosis in leukemia cells through a process mediated by oxidative damage, XIAP downregulation, and c-Jun N-terminal kinase 1 activation
-
Dai Y, Rahmani M, Dent Grant PS. 2005. Blockade of histone deacetylase inhibitor-induced RelA/p65 acetylation and NF-kappaB activation potentiates apoptosis in leukemia cells through a process mediated by oxidative damage, XIAP downregulation, and c-Jun N-terminal kinase 1 activation. Mol. Cell. Biol. 25:5429-5444. http://dx.doi.org/10.1128/MCB.25.13.5429-5444.2005.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 5429-5444
-
-
Dai, Y.1
Rahmani, M.2
Dent Grant, P.S.3
-
54
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW. 2004. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23:2369-2380. http://dx.doi.org/10.1038/sj.emboj.7600244.
-
(2004)
EMBO J
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
55
-
-
84880721384
-
Menin: a scaffold protein that controls gene expression and cell signaling
-
Matkar S, Thiel A, Hua X. 2013. Menin: a scaffold protein that controls gene expression and cell signaling. Trends Biochem. Sci. 38:394-402. http://dx.doi.org/10.1016/j.tibs.2013.05.005.
-
(2013)
Trends Biochem. Sci
, vol.38
, pp. 394-402
-
-
Matkar, S.1
Thiel, A.2
Hua, X.3
-
56
-
-
80655146232
-
RelA Ser276 phosphorylation-coupled Lys310 acetylation controls transcriptional elongation of inflammatory cytokines in respiratory syncytial virus infection
-
Brasier AR, Tian B, Jamaluddin M, Kalita MK, Garofalo RP, Lu M. 2011. RelA Ser276 phosphorylation-coupled Lys310 acetylation controls transcriptional elongation of inflammatory cytokines in respiratory syncytial virus infection. J. Virol. 85:11752-11769. http://dx.doi.org/10.1128 /JVI.05360-11.
-
(2011)
J. Virol
, vol.85
, pp. 11752-11769
-
-
Brasier, A.R.1
Tian, B.2
Jamaluddin, M.3
Kalita, M.K.4
Garofalo, R.P.5
Lu, M.6
-
57
-
-
33746403681
-
Controlling the elongation phase of transcription with P-TEFb
-
Peterlin BMB, Price DHD. 2006. Controlling the elongation phase of transcription with P-TEFb. Mol. Cell 23:297-305. http://dx.doi.org/10.1016/j.molcel.2006.06.014.
-
(2006)
Mol. Cell
, vol.23
, pp. 297-305
-
-
Peterlin, B.M.B.1
Price, D.H.D.2
-
58
-
-
0027297663
-
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
-
Pfeffer K, Matsuyama T, Kundig TM, Wakeham A, Kishihara K, Shahinian A, Wiegmann K, Ohashi PS, Kronke M, Mak TW. 1993. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 73: 457-467.
-
(1993)
Cell
, vol.73
, pp. 457-467
-
-
Pfeffer, K.1
Matsuyama, T.2
Kundig, T.M.3
Wakeham, A.4
Kishihara, K.5
Shahinian, A.6
Wiegmann, K.7
Ohashi, P.S.8
Kronke, M.9
Mak, T.W.10
-
59
-
-
0026074368
-
In vivo protective effect of tumour necrosis factor alpha against experimental infection with herpes simplex virus type 1
-
Rossol-Voth R, Rossol S, Schütt KH, Corridori S, de Cian W, Falke D. 1991. In vivo protective effect of tumour necrosis factor alpha against experimental infection with herpes simplex virus type 1. J. Gen. Virol. 72:143-147. http://dx.doi.org/10.1099/0022-1317-72-1-143.
-
(1991)
J. Gen. Virol
, vol.72
, pp. 143-147
-
-
Rossol-Voth, R.1
Rossol, S.2
Schütt, K.H.3
Corridori, S.4
de Cian, W.5
Falke, D.6
-
60
-
-
84878589884
-
Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium
-
Van Hauwermeiren F, Armaka M, Karagianni N, Kranidioti K, Vandenbroucke RE, Loges S, Van Roy M, Staelens J, Puimège L, Palagani A, Berghe WV, Victoratos P, Carmeliet P, Libert C, Kollias G. 2013. Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium. J. Clin. Invest. 123:2590-2603. http://dx.doi.org/10.1172 /JCI65624.
-
(2013)
J. Clin. Invest
, vol.123
, pp. 2590-2603
-
-
Van Hauwermeiren, F.1
Armaka, M.2
Karagianni, N.3
Kranidioti, K.4
Vandenbroucke, R.E.5
Loges, S.6
Van Roy, M.7
Staelens, J.8
Puimège, L.9
Palagani, A.10
Berghe, W.V.11
Victoratos, P.12
Carmeliet, P.13
Libert, C.14
Kollias, G.15
-
61
-
-
84878756188
-
Role of tissue protection in lethal respiratory viralbacterial coinfection
-
Jamieson AM, Pasman L, Yu S, Gamradt P, Homer RJ, Decker T, Medzhitov R. 2013. Role of tissue protection in lethal respiratory viralbacterial coinfection. Science 340:1230-1234. http://dx.doi.org/10.1126 /science.1233632.
-
(2013)
Science
, vol.340
, pp. 1230-1234
-
-
Jamieson, A.M.1
Pasman, L.2
Yu, S.3
Gamradt, P.4
Homer, R.J.5
Decker, T.6
Medzhitov, R.7
-
62
-
-
33750253585
-
Enhanced antiviral antibody secretion and attenuated immunopathology during influenza virus infection in nitric oxide synthase-2-deficient mice
-
Jayasekera JP, Vinuesa CG, Karupiah G, King NJC. 2006. Enhanced antiviral antibody secretion and attenuated immunopathology during influenza virus infection in nitric oxide synthase-2-deficient mice. J. Gen. Virol. 87:3361-3371. http://dx.doi.org/10.1099/vir.0.82131-0.
-
(2006)
J. Gen. Virol
, vol.87
, pp. 3361-3371
-
-
Jayasekera, J.P.1
Vinuesa, C.G.2
Karupiah, G.3
King, N.J.C.4
-
63
-
-
3242664636
-
Recognition of commensal microflora by Toll-like receptors is required for intestinalhomeostasis
-
Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F. 2004. Recognition of commensal microflora by Toll-like receptors is required for intestinalhomeostasis. Cell 118:229-241. http://dx.doi.org/10.1016/j.cell.2004.07.002.
-
(2004)
Cell
, vol.118
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
-
64
-
-
84857444508
-
B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage
-
Kirkland D, Benson A, Mirpuri J, Pifer R, Hou B, DeFranco AL, Yarovinsky F. 2012. B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage. Immunity 36:228-238. http://dx.doi.org/10.1016/j.immuni.2011.11.019.
-
(2012)
Immunity
, vol.36
, pp. 228-238
-
-
Kirkland, D.1
Benson, A.2
Mirpuri, J.3
Pifer, R.4
Hou, B.5
DeFranco, A.L.6
Yarovinsky, F.7
-
65
-
-
84869455238
-
MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice
-
Hoshi N, Schenten D, Nish SA, Walther Z, Gagliani N, Flavell RA, Reizis B, Shen Z, Fox JG, Iwasaki A, Medzhitov R. 2012. MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice. Nat. Commun. 3:1120. http://dx.doi.org/10.1038/ncom ms2113.
-
(2012)
Nat. Commun.
, vol.3
, pp. 1120
-
-
Hoshi, N.1
Schenten, D.2
Nish, S.A.3
Walther, Z.4
Gagliani, N.5
Flavell, R.A.6
Reizis, B.7
Shen, Z.8
Fox, J.G.9
Iwasaki, A.10
Medzhitov, R.11
-
66
-
-
79954552505
-
The super elongation complex (SEC) and MLL in development and disease
-
Smith E, Lin C, Shilatifard A. 2011. The super elongation complex (SEC) and MLL in development and disease. Genes Dev. 25:661-672. http://dx.doi.org/10.1101/gad.2015411.
-
(2011)
Genes Dev
, vol.25
, pp. 661-672
-
-
Smith, E.1
Lin, C.2
Shilatifard, A.3
-
67
-
-
77958111633
-
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
-
Malik S, Roeder RG. 2010. The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nat. Rev. Genet. 11: 761-772. http://dx.doi.org/10.1038/nrg2901.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 761-772
-
-
Malik, S.1
Roeder, R.G.2
-
68
-
-
84872376792
-
The Mediator complex and transcription elongation
-
Conaway RC, Conaway JW. 2013. The Mediator complex and transcription elongation. Biochim. Biophys. Acta 1829:69-75. http://dx.doi.org/10.1016/j.bbagrm.2012.08.017.
-
(2013)
Biochim. Biophys. Acta
, vol.1829
, pp. 69-75
-
-
Conaway, R.C.1
Conaway, J.W.2
-
69
-
-
76349090199
-
CDK8 is a positive regulator of transcriptional elongation within the serum response network
-
Donner AJ, Ebmeier CC, Taatjes DJ, Espinosa JM. 2010. CDK8 is a positive regulator of transcriptional elongation within the serum response network. Nat. Struct. Mol. Biol. 17:194-201. http://dx.doi.org/10.1038 /nsmb.1752.
-
(2010)
Nat. Struct. Mol. Biol
, vol.17
, pp. 194-201
-
-
Donner, A.J.1
Ebmeier, C.C.2
Taatjes, D.J.3
Espinosa, J.M.4
-
70
-
-
79959939884
-
Human mediator subunit MED26 functions as a docking site for transcription elongation factors
-
Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CAS, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, Florens L, Seidel CW, Lin C, Smith ER, Shilatifard A, Conaway RC, Conaway JW. 2011. Human mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell 146:92-104. http://dx.doi.org/10.1016/j.cell.2011.06.005.
-
(2011)
Cell
, vol.146
, pp. 92-104
-
-
Takahashi, H.1
Parmely, T.J.2
Sato, S.3
Tomomori-Sato, C.4
Banks, C.A.S.5
Kong, S.E.6
Szutorisz, H.7
Swanson, S.K.8
Martin-Brown, S.9
Washburn, M.P.10
Florens, L.11
Seidel, C.W.12
Lin, C.13
Smith, E.R.14
Shilatifard, A.15
Conaway, R.C.16
Conaway, J.W.17
-
71
-
-
84869054253
-
Cross-talk among RNA polymerase II kinases modulates C-terminal domain phosphorylation
-
Devaiah BN, Singer DS. 2012. Cross-talk among RNA polymerase II kinases modulates C-terminal domain phosphorylation. J. Biol. Chem. 287:38755-38766. http://dx.doi.org/10.1074/jbc.M112.412015.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 38755-38766
-
-
Devaiah, B.N.1
Singer, D.S.2
-
72
-
-
0029007193
-
Interleukin-6-deficient mice are highly susceptible to Listeria monocytogenes infection: correlation with inefficient neutrophilia
-
Dalrymple SA, Lucian LA, Slattery R, McNeil T, Aud DM, Fuchino S, Lee F, Murray R. 1995. Interleukin-6-deficient mice are highly susceptible to Listeria monocytogenes infection: correlation with inefficient neutrophilia. Infect. Immun. 63:2262-2268.
-
(1995)
Infect. Immun.
, vol.63
, pp. 2262-2268
-
-
Dalrymple, S.A.1
Lucian, L.A.2
Slattery, R.3
McNeil, T.4
Aud, D.M.5
Fuchino, S.6
Lee, F.7
Murray, R.8
-
73
-
-
0031227868
-
Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice
-
Labow M, Shuster D, Zetterstrom M, Nunes P, Terry R, Cullinan EB, Bartfai T, Solorzano C, Moldawer LL, Chizzonite R, McIntyre KW. 1997. Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice. J. Immunol. 159:2452-2461.
-
(1997)
J. Immunol.
, vol.159
, pp. 2452-2461
-
-
Labow, M.1
Shuster, D.2
Zetterstrom, M.3
Nunes, P.4
Terry, R.5
Cullinan, E.B.6
Bartfai, T.7
Solorzano, C.8
Moldawer, L.L.9
Chizzonite, R.10
McIntyre, K.W.11
-
74
-
-
54449091097
-
Opposing functions of IKKbeta during acute and chronic intestinal inflammation
-
Eckmann L, Nebelsiek T, Fingerle AA, Dann SM, Mages J, Lang R, Robine S, Kagnoff MF, Schmid RM, Karin M, Arkan MC, Greten FR. 2008. Opposing functions of IKKbeta during acute and chronic intestinal inflammation. Proc. Natl. Acad. Sci. U. S. A. 105:15058-15063. http://dx.doi.org/10.1073/pnas.0808216105.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A
, vol.105
, pp. 15058-15063
-
-
Eckmann, L.1
Nebelsiek, T.2
Fingerle, A.A.3
Dann, S.M.4
Mages, J.5
Lang, R.6
Robine, S.7
Kagnoff, M.F.8
Schmid, R.M.9
Karin, M.10
Arkan, M.C.11
Greten, F.R.12
-
75
-
-
33645116785
-
NF- kappa B activation as a pathological mechanism of septic shock and inflammation
-
Liu SF, Malik AB. 2006. NF-kappa B activation as a pathological mechanism of septic shock and inflammation. Am. J. Physiol. Lung Cell. Mol. Physiol. 290:L622-L645. http://dx.doi.org/10.1152/ajplung.00477.2005.
-
(2006)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.290
-
-
Liu, S.F.1
Malik, A.B.2
-
76
-
-
80052955256
-
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
-
Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J, Jacobs HM, Kastritis E, Gilpatrick T, Paranal RM, Qi J, Chesi M, Schinzel AC, McKeown MR, Heffernan TP, Vakoc CR, Bergsagel PL, Ghobrial IM, Richardson PG, Young RA, Hahn WC, Anderson KC, Kung AL, Bradner JE, Mitsiades CS. 2011. BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 146:904-917. http://dx.doi.org/10.1016/j.cell.2011.08.017.
-
(2011)
Cell
, vol.146
, pp. 904-917
-
-
Delmore, J.E.1
Issa, G.C.2
Lemieux, M.E.3
Rahl, P.B.4
Shi, J.5
Jacobs, H.M.6
Kastritis, E.7
Gilpatrick, T.8
Paranal, R.M.9
Qi, J.10
Chesi, M.11
Schinzel, A.C.12
McKeown, M.R.13
Heffernan, T.P.14
Vakoc, C.R.15
Bergsagel, P.L.16
Ghobrial, I.M.17
Richardson, P.G.18
Young, R.A.19
Hahn, W.C.20
Anderson, K.C.21
Kung, A.L.22
Bradner, J.E.23
Mitsiades, C.S.24
more..
-
77
-
-
80055000824
-
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
-
Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR. 2011. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature 478:524-528. http://dx.doi.org/10.1038 /nature10334.
-
(2011)
Nature
, vol.478
, pp. 524-528
-
-
Zuber, J.1
Shi, J.2
Wang, E.3
Rappaport, A.R.4
Herrmann, H.5
Sison, E.A.6
Magoon, D.7
Qi, J.8
Blatt, K.9
Wunderlich, M.10
Taylor, M.J.11
Johns, C.12
Chicas, A.13
Mulloy, J.C.14
Kogan, S.C.15
Brown, P.16
Valent, P.17
Bradner, J.E.18
Lowe, S.W.19
Vakoc, C.R.20
more..
-
78
-
-
84865229469
-
Small-molecule inhibition ofBRDTfor male contraception
-
Matzuk MM, McKeown MR, Filippakopoulos P, Li Q, Ma L, Agno JE, Lemieux ME, Picaud S, Yu RN, Qi J, Knapp S, Bradner JE. 2012. Small-molecule inhibition ofBRDTfor male contraception. Cell 150:673- 684. http://dx.doi.org/10.1016/j.cell.2012.06.045.
-
(2012)
Cell
, vol.150
, pp. 673-684
-
-
Matzuk, M.M.1
McKeown, M.R.2
Filippakopoulos, P.3
Li, Q.4
Ma, L.5
Agno, J.E.6
Lemieux, M.E.7
Picaud, S.8
Yu, R.N.9
Qi, J.10
Knapp, S.11
Bradner, J.E.12
-
79
-
-
84867316537
-
BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia
-
Ott CJ, Kopp N, Bird L, Paranal RM, Qi J, Bowman T, Rodig SJ, Kung AL, Bradner JE, Weinstock DM. 2012. BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia. Blood 120:2843-2852. http://dx.doi.org/10.1182/blood-2012-02-413021.
-
(2012)
Blood
, vol.120
, pp. 2843-2852
-
-
Ott, C.J.1
Kopp, N.2
Bird, L.3
Paranal, R.M.4
Qi, J.5
Bowman, T.6
Rodig, S.J.7
Kung, A.L.8
Bradner, J.E.9
Weinstock, D.M.10
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