Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways

European Journal of Pharmacology

Volumn 724, Issue 1, 2014, Pages 168-174

  Chen, Haixia ^a,b   Sohn, Johann ^b   Zhang, Likang ^a   Tian, Jingge ^a   Chen, Shuhan ^a   Bjeldanes, Leonard F ^b  

^a TIANJIN UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chicanine; ERK; I B ; Inflammatory cytokines; MAPK

Indexed keywords

CHICANINE; CYCLOOXYGENASE 2; CYTOKINE; GRANULOCYTE COLONY STIMULATING FACTOR; HERBACEOUS AGENT; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; PROSTAGLANDIN E2; SCHISANDRA CHINENSIS EXTRACT; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DOWN REGULATION; DRUG ISOLATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; ENZYME REGULATION; MACROPHAGE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SCHISANDRA CHINENSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

CHICANINE; ERK; INFLAMMATORY CYTOKINES; IΚBΑ; MAPK;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CYTOKINES; DINOPROSTONE; I-KAPPA B PROTEINS; LIGNANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRITES; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84892465755     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.12.016     Document Type: Article

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