SMILE inhibits BMP-2-induced expression of osteocalcin by suppressing the activity of the RUNX2 transcription factor in MC3T3E1 cells

Bone

Volumn 61, Issue , 2014, Pages 10-18

  Jang, Hoon ^a,b   Kim, Eun Jung ^a   Park, Jae Kyung ^a   Kim, Dong Ern ^a   Kim, Hyoung Joo ^a   Sun, Wu Sheng ^a   Hwang, Seongsoo ^c   Oh, Keon Bong ^c   Koh, Jeong Tae ^d   Jang, Won Gu ^e   Lee, Jeong Woong ^a,b  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

^c National Institute of Animal Science   (South Korea)

^d Chonnam National University   (South Korea)

^e Daegu University   (South Korea)

Author keywords

BMP2; Osteoblast; Osteocalcin; Runx2; SMILE

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; LEUCINE ZIPPER PROTEIN; OSTEOCALCIN; SMILE PROTEIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ALP GENE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENE; GENE DELETION; GENE REPRESSION; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; OSSIFICATION; OSTEOCALCIN GENE; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

BMP2; OSTEOBLAST; OSTEOCALCIN; RUNX2; SMILE;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BLOTTING, WESTERN; BONE MORPHOGENETIC PROTEIN 2; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CORE BINDING FACTOR ALPHA 1 SUBUNIT; GENE EXPRESSION REGULATION; HUMANS; MICE; OSTEOBLASTS; OSTEOCALCIN; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84892455691     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2013.12.028     Document Type: Article

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