Protective effects of Nigella sativa on metabolic syndrome in menopausal women

Advanced Pharmaceutical Bulletin

Volumn 4, Issue 1, 2014, Pages 29-33

  Ibrahim, Ramlah Mohamad ^a   Hamdan, Nurul Syima ^a   Ismail, Maznah ^a   Saini, Suraini Mohd ^a   Rashid, Saiful Nizam Abd ^a   Latiff, Latiffah Abd ^a   Mahmud, Rozi ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Hyperglycemia; Hyperlipidemic; Menopause; Metabolic syndrome; Nigella sativa

Indexed keywords

CHOLESTEROL; GLUCOSE; HERBACEOUS AGENT; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; TRIACYLGLYCEROL;

ADJUVANT THERAPY; ADULT; ANTHROPOMETRIC PARAMETERS; ARTICLE; BIOCHEMICAL PARAMETERS; BLACK CUMIN; BODY WEIGHT; CHEMICAL PARAMETERS; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; MALAYSIA; MENOPAUSE; METABOLIC SYNDROME X; MIDDLE AGED; MORNING DOSAGE; PLANT SEED; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84892447586     PISSN: 22285881     EISSN: 22517308     Source Type: Journal    
DOI: 10.5681/apb.2014.005     Document Type: Article

References (30)

1. Atsma F, Bartelink ML, Grobbee DE, Van Der Schouw YT. Postmenopausal status and early menopause as independent risk factors for cardiovascular disease: a meta-analysis. Menopause 2006;13(2):265-79.
2. Schneider JG, Tompkins C, Blumenthal RS, Mora S. The metabolic syndrome in women. Cardiol Rev 2006;14(6):286-91.
3. Wellons M, Ouyang P, Schreiner PJ, Herrington DM, Vaidya D. Early menopause predicts future coronary heart disease and stroke: the Multi-Ethnic Study of Atherosclerosis. Menopause 2012;19(10):1081-7.
4. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA 2001;285(19):2486-97.
5. Goyal S, Baruah M, Devi R, Jain K. Study on Relation of Metabolic Syndrome with Menopause. Ind J Clin Biochem 2013;28(1):55-60.
6. Janssen I, Powell LH, Crawford S, Lasley B, Sutton-Tyrrell K. Menopause and the metabolic syndrome: the Study of Women's Health Across the Nation. Arch Intern Med 2008;168(14):1568-75.
7. Lin WY, Yang WS, Lee LT, Chen CY, Liu CS, Lin CC, et al. Insulin resistance, obesity, and metabolic syndrome among non-diabetic pre- and post-menopausal women in North Taiwan. Int J Obes (Lond) 2006;30(6):912-7.
8. Ainy E, Mirmiran P, Zahedi Asl S, Azizi F. Prevalence of metabolic syndrome during menopausal transition Tehranian women: Tehran Lipid and Glucose Study (TLGS). Maturitas 2007;58(2):150-5.
9. Kadir AA, Hamid HA, Hussain NHN. Metabolic syndrome among postmenopausal women: Prevalence of metabolic syndrome and its associated factors among postmenopausal women at Hospital Universiti Sains Malaysia. Int J Coll Res Intern Med Public Health 2012;4(6):1286-96.
10. Khoddami A, Ghazali HM, Yassoralipour A, Ramakrishnan Y, Ganjloo A. Physicochemical characteristics of Nigella Seed (Nigella sativa L.) oil as affected by different extraction Methods. J Am Oil Chem Soc 2011;88(4):533-40.
11. Salehisurmaghi MH. Nigella sativa. Herbal Med Herbal Therapy 2008;2:216-9.
12. Parhizkar S, Latif LA, Rahman SA, Dollah MA. Preventive effect of Nigella sativa on metabolic syndrome in menopause induced rats. J Med Plants Res 2011;5(8):1478-84.
13. Carr MC. The emergence of the metabolic syndrome with menopause. J Clin Endocrinol Metab 2003;88(6):2404-11.
14. Najmi A, Haque SF, Naseeruddin M, Khan RA. Effect of Nigella Sativa oil on various clinical and biochemical parameters of metabolic syndrome. Int J Diabetes Metabolism 2008;16(2):85-7.
15. Tasawar Z, Siraj Z, Ahmad N, Lashari MH. The effects of Nigella sativa(Kalonji) on lipid profile in patients with stable coronary artery disease in Multan Pakistan. Pak J Nutr 2011;10(2):162-7.
16. Sabzghabaee AM, Dianatkhah M, Sarrafzadegan N, Asgary S, Ghannadi A. Clinical evaluation of Nigella sativa seeds for the treatment of hyperlipidemia: a randomized, placebo controlled clinical trial. Med Arh 2012;66(3):198-200.
17. Bhatti IU, Ur Rehman F, Khan MA, Marwat SK. Effect of prophetic medicine kalonji (Nigella sativa L.) on lipid profile of human beings. An in vivo approach. World Appl Sci J 2009;6(8):1053-7.
18. Talati R, Baker WL, Pabilonia MS, White CM, Coleman CI. The effects of barley-derived soluble fiber on serum lipids. Ann Fam Med 2009;7(2):157-63.
19. Moruisi KG, Oosthuizen W, Opperman AM. Phytosterols/stanols lower cholesterol concentrations in familial hypercholesterolemic subjects: a systematic review with meta-analysis. J Am Coll Nutr 2006;25(1):41-8.
20. Al-Naqeeb G, Ismail M, Al-Zubairi AS. Fatty acid profile, α-tocopherol content and total antioxidant activity of oil extracted from N. sativa seeds. Int J Pharmacol 2009;5(4);244-50.
21. Bamosa AO, Kaatabi H, Lebdaa FM, Elq AM, Al-Sultanb A. Effect of Nigella sativa seeds on the glycemic control of patients with type 2 diabetes mellitus. Indian J Physiol Pharmacol 2010;54(4):344-54.
22. Mohtashami R, Amini M, Fallah Huseini H, Ghamarchehre M, Sadeqhi Z, Hajiagaee R, et al. Blood glucose lowering effects of Nigella Sativa L. seeds oil in healthy volunteers: A Randomized, Double-blind, placebo-controlled clinical trial. J Med Plants 2011;39(10):90-4.
23. Alsaif MA. Effect of Nigella sativa oil on impaired glucose tolerance and insulin insensitivity induced by high-fat-diet and turpentine-induced trauma. Pak J Biol Sci 2008;11(8):1093-9.
24. El-Dakhakhny M, Mady N, Lembert N, Ammon HP. The hypoglycemic effect of Nigella sativa oil is mediated by extrapancreatic actions. Planta medica 2002;68(5):465-6.
25. Fararh KM, Shimizu Y, Shiina T, Nikami H, Ghanem MM, Takewaki T. Thymoquinone reduces hepatic glucose production in diabetic hamsters. Res Vet Sci 2005;79(3):219-23.
26. Hamdy NM, Taha RA. Effects of Nigella sativa oil and thymoquinone on oxidative stress and neuropathy in streptozotocin-induced diabetic rats. Pharmacology 2009;84(3):127-34.
27. Meddah B, Ducroc R, El Abbes Faouzi M, Eto B, Mahraoui L, Benhaddou-Andaloussi A, et al. Nigella sativa inhibits intestinal glucose absorption and improves glucose tolerance in rats. J Ethnopharmacol 2009;121(3):419-24.
28. Ali BH, Blunden G. Pharmacological and toxicological properties of Nigella sativa. Phytother Res 2003;17(4):299-305.
29. Talati R, Baker WL, Pabilonia MS, White CM, Coleman CI. The effects of barley-derived soluble fiber on serum lipids. Ann Fam Med 2009;7(2):157-63.
30. Cheikh-Rouhoua S, Besbesa S, Lognayb G, Bleckerc C, Deroannec C, Attia H. Sterol composition of black cumin (Nigella sativa L.) and Aleppo pine (Pinushalepensis Mill.) seed oils. J Food Compos Anal 2008;21(2):162-8.