Effect of N. sativa oil on impaired glucose tolerance and insulin insensitivity induced by high-fat-diet and turpentine-induced trauma

Pakistan Journal of Biological Sciences

Volumn 11, Issue 8, 2008, Pages 1093-1099

  Alsaif, Mohammed A ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Butter oil; Glucose tolerance; Insulin sensitivity; N. Sativa oil; Turpentine

Indexed keywords

CARAWAY OIL; INSULIN; TURPENTINE; VEGETABLE OIL;

ANIMAL; AREA UNDER THE CURVE; ARTICLE; BLOOD; BODY WEIGHT; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; FAT INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; INJURY; INSULIN RESISTANCE; MALE; METABOLISM; ORGAN SIZE; RAT; TIME; WISTAR RAT;

ANIMALS; AREA UNDER CURVE; BLOOD GLUCOSE; BODY WEIGHT; DIETARY FATS; GLUCOSE INTOLERANCE; INSULIN; INSULIN RESISTANCE; MALE; ORGAN SIZE; PLANT OILS; RATS; RATS, WISTAR; TIME FACTORS; TURPENTINE; WOUNDS AND INJURIES;

ANIMALIA; RATTUS;

EID: 53749091796     PISSN: 10288880     EISSN: 18125735     Source Type: Journal    
DOI: 10.3923/pjbs.2008.1093.1099     Document Type: Article

References (35)

1. Al-Hader, A., M. Aqel and Z. Hasan, 1993. Hypoglycemic effects of the volatile oil of Nigella sativa seeds. Int. J. Pharm., 31 (2): 96-100.
2. Ali, B.H. and G. Blunden, 2003. Pharmacological and toxicological properties of Nigella sativa. Phytother. Res., 17(4): 299-305.
3. Alsaif, M.A. and M.M.S. Duwaihy, 2004. Influence of dietary fat quantity and composition on glucose tolerance and insulin sensitivity in rats. Nutr. Res., 24: 417-425.
4. Alsaif, M.A., 2004. Effect of dietary fats on glucose tolerance, insulin sensitivity and membrane free fatty acid in rats. Pak. J. Nutr., 3 (2): 56-63.
5. Barton, R.N. and B.J. Passingham, 1980. Evidence for a role of glucocorticoids in the development of insulin resistance after ischaemic limb injury in the rat. J. Endocrinol., 86 (2): 363-370.
6. Black, P.R., D.C. Brooks, P.Q. Bessey, R.R. Wolfe and D.W. Wilmore, 1982. Mechanims of insulin resistance following injury. Ann. Surg., 196 (4): 420-435.
7. Bloomgarden, Z.T., 1999. American diabetes association annual meeting, 1998. Insulin resistance, exercise and obesity. Diabstes Care, 22 (11): 517-522.
8. Davidson, M.B. and D. Garvey, 1993. Studies on mechanisms of hepatic insulin resistance in fafeteriafed rats. Am. J. Physiol. Endocrinol. Medtab., 264 (27): E18-E23.
9. Davies, J.W.L., 1982. Physiological Responses to Burning Injury. Academic Press, London.
10. De Luca, C. and J.M. Olefsky, 2008. Inflammation and insulin resistance. FEBS. Lett., 582 (1): 97-105.
11. El-Dakhakhny, M., N.N. Madi, N. Lembert and H.P. Ammon, 2002a. Nigella sativa oil, nigellone and derived thymoquinone inhibit synthesis of 5-lipoxygnase products in polymorphonuclear leukocytes from rats. J. Ethnopharmacol., 81 (2): 161-164.
12. El-Dakhakhny, M., N. Mady, N. Lembert and H.P. Ammon, 2002b. The hypoglycemic effect of Nigella sativa oil is mediated by extrapancreatic actions. Planta Med., 68 (5): 465-466.
13. Fararh, K.M., Y. Atoji, Y. Shimizu and T. Takewaki, 2002. Isulinotropic properties of Nigella sativa oil in streptozotocin plus Nicotinamide diabetic hamster. Res. Vet. Sci., 73 (3): 279-282.
14. Fararh, K.M., Y. Atoji, Y. Shimizu, T. Shiina, H. Nikami and T. Takewaki, 2004. Mechanisms of the hypoglycaemic and immunopotentiating effects of Nigella sativa L. oil in streptozotoin-induced diabetic hamsters. Res. Vet. Sci., 77 (2): 123-129.
15. Frayn, K.N., 1986. Hormonal control of metabolism in trauma and sepsis. Clin. Endocrinol., 24 (5): 577-599.
16. Houghton, P.J., R. Zarka, B. de la Heras and J.R.S. Hoult, 1995. Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Medica, 61 (1): 33-36.
17. Kaleem, M., D. Kirmani, M. Asif, Q. Ahmed and B. Bano, 2006. Biochemical effects of Nigella sativa L. seeds in diabetic rats. Indian J. Exp. Biol., 44 (9): 745-748.
18. Kanter, M., I. Meral, Z. Yener, H. Ozbek and H. Demir, 2003. Partial regeneration/proliferation of the beta-cells in the islets of Langerhans by Nigella sativa L. in streptozotocin-induced diabetic rats. Tohoku. J. Exp. Med., 210 (4): 213-219.
19. Kinney, J.M., 1977. The Metabolic Response to Injury. In: Nutritional Aspects of Care in the Critically Ill, Richards, J.R. and J.M. Kinney (Eds.). Edinburgh: Churchill Livingston.
20. Lovejoy, J.C., C.M. Champagne, S.R. Smith, J.P. DeLany, G.A. Bray and M. Lefevre, 2001. Relationship of dietary fat and serum cholesterol ester and phospholipids fatty acids to markers of insulin resistance in men and women with a range of glucose tolerance. Metabolism, 50 (1): 86-92.
21. Mizock, B.A., 1995. Alterations in carbohydrate metabolism during stress: Areview of the literature. Am. J. Med., 89 (1): 98-184.
22. Pan, D.A., A.J. Hulburt and L.H. Storlien, 1994. Dietary fats, membrane phospholipids and obesity. J. Nutr., 124 (9): 1555-1565.
23. Petersen, K.F., S. Dufour, D. Befroy, R. Garica and G.I. Shulman, 2004. Impaired mitochondrial activity in the insulin-resistance offspring of patients with type 2 diabetes. N. Engl. J. Med., 350 (7): 664-671.
24. Ramirez, R., J.M. Lopez, F.J. Bendoya and R. Goberna, 1990. Effect of high-carbohydrate of high-fat diet on carbohydrate metabolism and insulin secretion in the normal rat. Diabetes Res., 15 (4): 179-183.
25. Richid, H., H. Chevassus, R. Nmila, C. Giral, P. Petit, M. Chokairi and Y. Sauvaire, 2004. Nigella sativa seed extracts enhance glucose-induced insulin release from ratisolated Langerhans islets. Fundam. Clin. Pharmacol., 18 (5): 525-529.
26. Storlien, L.H., A.B. Jenkins and D.J. Chisholm et al., 1991. Influence of dietary fat composition on development of insulin resistance in rats: Relationship of muscle triglyceride and ω-3 fatty acids in muscle phospholipids. Diabetes, 40 (2): 280-289.
27. Storlien, L.H., D.A. Pan, M. Milner and S. Lillioja, 1993. Skeletal muscle membrane lipid composition is related to adiposity in man. Obes. Res., 1: 77S (Abs.).
28. Strommer, L., M. Wickbom, F. Wang, M.K. Herrington, C.G. Ostenson, U. Arnelo and J. Permert, 2002. Early impairment of insulin secretion in rats after surgical trauma. Eur. J. Endocrinol., 147 (6): 825-833.
29. Thorell, A., S. Efendic, M. Gutniak, T. Haggmark and O. Ljungqvist, 1994. Insulin resistance after abdominal surgery, Br. J. Surg., 81 (1): 59-63.
30. Virkamaki, A. and H. Yki-Jarvinen, 1994. Mechanisms of insulin resistance during acute endotoxemia. Endocrinol., 134 (5): 2072-2078.
31. Wiersma, M.M., I.M. Bakker and J.K. Radder, 1993. Effect of high fat feeding on glucose tolerance in neonatally streptozotocin-induced rats at 3 and 6 month of age. Annals New York, Academy Science, pp: 228-236.
32. Woloski, B.M.R.N.J. and J.C. Jamieson, 1987. Rat corticotrophin insulin and thyroid hormone levels during the acute-phase response to inflammation. Comp. Biochem. Phsiol. A Comp. Physiol., 86 (1): 15-19.
33. Woolfson, A.M.J., R.V. Heatly and S.P. Allison, 1977. The Significantly of Insulin in The Metabolic Response to Injury. In: Nutritional Aspects of Care in the Critically Ill, Richards, J.R. and J.M. Kinney (Eds.). Edinburgh: Churchill Livinstone.
34. Wusteman, M., D.G.D. Wight and M. Elia, 1990. Protein metabolism after injury with turpentine: A rat model for clinical trauma. Am. J. Physiol., 259 (6 Pt 1): E763-E769.
35. Zaoui, A., Y. Cherrah, N. Mahassini, K. Alaoui, H. Amarouch and M. Hassar, 2002. Acute and chronic toxicity of Nigella sativa fixed oil. Phytomedicine, 9 (1): 69-74.