Inhibition of glycogen synthase kinase (GSK)-3-β improves liver microcirculation and hepatocellular function after hemorrhagic shock

European Journal of Pharmacology

Volumn 724, Issue 1, 2014, Pages 175-184

  Jellestad, Lena ^a   Fink, Tobias ^a   Pradarutti, Sascha ^a   Kubulus, Darius ^a   Wolf, Beate ^a   Bauer, Inge ^b   Thiemermann, Chris ^c   Rensing, Hauke ^d  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^c ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^d Leopoldina Hospital   (Germany)

Author keywords

Cytokine; GSK 3; Hemorrhagic shock; Intravital microscopy; Plasma disappearance rate

Indexed keywords

4 BENZYL 2 METHYL 1,2,4 THIAZOLIDINE 3,5 DIONE; DIMETHYL SULFOXIDE; GLUTATHIONE TRANSFERASE ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; INDOCYANINE GREEN; PLACEBO; PROPIDIUM IODIDE; RINGER SOLUTION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CONVALESCENCE; DRUG TARGETING; ENZYME INHIBITION; HEMODYNAMICS; HEMORRHAGIC SHOCK; LIVER FUNCTION; LIVER INJURY; LIVER MICROCIRCULATION; LIVER PERFUSION; LIVER PROTECTION; LIVER SINUSOID; MALE; MICROCIRCULATION; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; RAT; RAT MODEL; RESUSCITATION; SHAM PROCEDURE;

CYTOKINE; GSK-3; HEMORRHAGIC SHOCK; INTRAVITAL MICROSCOPY; PLASMA DISAPPEARANCE RATE;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; GLUTAMATE DEHYDROGENASE; GLUTATHIONE TRANSFERASE; GLYCOGEN SYNTHASE KINASE 3; HEPATOCYTES; INTERLEUKIN-10; LIVER; MALE; MICROCIRCULATION; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; SHOCK, HEMORRHAGIC; THIADIAZOLES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84892446993     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.12.029     Document Type: Article

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