Reduced expression of DENND2D through promoter hypermethylation is an adverse prognostic factor in squamous cell carcinoma of the esophagus

Oncology Reports

Volumn 31, Issue 2, 2014, Pages 693-700

  Hibino, Soki ^a   Kanda, Mitsuro ^a   Oya, Hisaharu ^a   Takami, Hideki ^a   Shimizu, Dai ^a   Nomoto, Shuji ^a   Hishida, Mitsuhiro ^a   Niwa, Yukiko ^a   Koike, Masahiko ^a   Yamada, Suguru ^a   Nishikawa, Yoko ^a   Asai, Mikako ^a   Nakayama, Goro ^a   Fujii, Tsutomu ^a   Sugimoto, Hiroyuki ^a   Fujiwara, Michitaka ^a   Kodera, Yasuhiro ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

DENND2D; DNA methylation; Esophageal cancer; Expression; Tumor suppressor

Indexed keywords

DENND2D PROTEIN; MESSENGER RNA; REGULATOR PROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER CELL; CANCER PROGNOSIS; CLINICAL FEATURE; CONTROLLED STUDY; DENND2D GENE; DISEASE MARKER; DNA METHYLATION; DOWN REGULATION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CPG ISLANDS; DNA METHYLATION; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; MALE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 84892406581     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2901     Document Type: Article

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