Childhood exposure to manganese and postural instability in children living near a ferromanganese refinery in Southeastern Ohio

Neurotoxicology and Teratology

Volumn 41, Issue , 2014, Pages 71-79

  Rugless, Fedoria ^a   Bhattacharya, Amit ^a   Succop, Paul ^a   Dietrich, Kim N ^a   Cox, Cyndy ^a   Alden, Jody ^a   Kuhnell, Pierce ^a   Barnas, Mary ^b   Wright, Robert ^c   Parsons, Patrick J ^d,e   Praamsma, Meredith L ^d,e   Palmer, Christopher D ^d,e   Beidler, Caroline ^f   Wittberg, Richard ^g   Haynes, Erin N ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b MARIETTA COLLEGE   (United States)

^c HARVARD UNIVERSITY   (United States)

^d WADSWORTH CENTER   (United States)

^e STATE UNIVERSITY OF NEW YORK   (United States)

^f Neighbors for Clean Air   (United States)

^g Mid Ohio Valley Health Department   (United States)

Author keywords

Appalachian American; Children; Lead; Manganese; Postural balance

Indexed keywords

LEAD; MANGANESE;

ARTICLE; BALANCE DISORDER; BODY EQUILIBRIUM; CHEMICAL INDUSTRY; CHILD; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; HAIR LEVEL; HUMAN; HUMAN TISSUE; LEAD BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MANGANESE BLOOD LEVEL; MOTOR PERFORMANCE; POSTURAL INSTABILITY; PRIORITY JOURNAL; RESIDENTIAL AREA; UNITED STATES;

APPALACHIAN AMERICAN; CHILDREN; LEAD; MANGANESE; POSTURAL BALANCE;

AGE FACTORS; CHILD; ENVIRONMENT; ENVIRONMENTAL EXPOSURE; FEMALE; HUMANS; INTELLIGENCE; IRON; MALE; MANGANESE; MANGANESE POISONING; OHIO; POSTURAL BALANCE; SENSATION DISORDERS; SPECTROPHOTOMETRY, ATOMIC;

EID: 84892390674     PISSN: 08920362     EISSN: 18729738     Source Type: Journal    
DOI: 10.1016/j.ntt.2013.12.005     Document Type: Article

References (73)

1. Aschner M. Manganese: brain transport and emerging research needs. Environ Health Perspect 2000, 108:429-432.
2. Aschner M., Gannon M. Manganese (Mn) transport across the rat blood-brain barrier: saturable and transferrin-dependent transport mechanisms. Brain Res Bull 1994, 33:345-349.
3. Aschner M. The transport of manganese across the blood-brain barrier. Neurotoxicology 2006, 27:311-344.
4. ATSDR (Agency for Toxic Substances, Disease Registry) Division of Health Assessment and Consultation and Division of Health Education and Promotion 2001, Hair Analysis Panel Discussion, Atlanta, Georgia.
5. Agency for Toxic Substances, Disease Registry (ATSDR) Toxicological profile for manganese 2012, U.S. Department of Health and Human Services, Public Health Service, Atlanta, GA.
6. Bacsi A.M., Colebatch J.G. Evidence for reflex and perceptual vestibular contributions to postural control. Exp Brain Res 2005, 160:22-28.
7. Barratt W. The Barratt simplified measure of social status 2006, Indiana State University, Terre Haute, IN.
8. Bhattacharya A., Shukla R., Dietrich K., Bornschein R., Berger O. Effect of early lead exposure on children's postural balance. Dev Med Child Neurol 1995, 37:861-878.
9. Bhattacharya A., Shukla R., Dietrich K.N., Bornschein R.L. Effect of early lead exposure on the maturation of children's postural balance: a longitudinal study. Neurotoxicol Teratol 2006, 28:376-385.
10. Bhattacharya A., Shukla R., Auyang E.D., Dietrich K.N., Bornschein R. Effect of succimer chelation therapy on postural balance and gait outcomes in children with early exposure to environmental lead. Neurotoxicology 2007, 28:686-695.
11. Bhattacharya A., Shukla R., Bornschein R.L., Dietrich K.N., Keith R. Lead effects on postural balance of children. Environ Health Perspect 1990, 89:35-42.
12. Bhattacharya A., Shukla R., Bornschein R., Dietrich K., Kopke J.E. Postural disequilibrium quantification in children with chronic lead exposure: a pilot study. Neurotoxicology 1988, 9:327-340.
13. Bhattacharya A., Morgan R., Shukla R., Ramakrishanan H.K., Wang L. Noninvasive estimation of afferent inputs for postural stability under low levels of alcohol. Ann Biomed Eng 1987, 15:533-550.
14. Birdsall R.E., Kiley M.P., Segu Z.M., Palmer C.D., Madera M., Gump B.B., et al. Effects of lead and mercury on the blood proteome of children. J Proteome Res 2010, 9:4443-4453.
15. Bock N.A., Paiva F.F., Nascimento G.C., Newman J.D., Silva A.C. Cerebrospinal fluid to brain transport of manganese in a non-human primate revealed by MRI. Brain Res 2008, 1198:160-170.
16. Bouchard M.F., Sauvé S., Barbeau B., Legrand M., Brodeur M.É., Bouffard T., et al. Intellectual impairment in school-age children exposed to manganese from drinking water. Environ Health Perspect 2011, 119:138-143.
17. Bowler R.M., Roels H.A., Nakagawa S., Drezgic M., Diamond E., Park R., et al. Dose-effect relationships between manganese exposure and neurological, neuropsychological and pulmonary function in confined space bridge welders. Occup Environ Med 2007, 64:167-177.
18. Brenneman K.A., Wong B.A., Buccellato M.A., Costa E.R., Gross E.A., Dorman D.C. Direct olfactory transport of inhaled manganese ((54)MnCl(2)) to the rat brain: toxicokinetic investigations in a unilateral nasal occlusion model. Toxicol Appl Pharmacol 2000, 169(3):238-248.
19. Centers for Disease Control, Prevention (CDC). CDC response to advisory committee on childhood lead poisoning prevention recommendations in "low level lead exposure harms children: a renewed call for primary prevention [Internet]. Available from. http://www.cdc.gov/nceh/lead/acclpp/cdc_response_lead_exposure_recs.pdf.
20. Claus Henn B., Kim J., Wessling-Resnick M., Téllez-Rojo M.M., Jayawardene I., Ettinger A.S., et al. Associations of iron metabolism genes with blood manganese levels: a population-based study with validation data from animal models. Environ Health. 2011, 10:97.
21. Crossgrove J.S., Allen D.D., Bukaveckas B.L., Rhineheimer S.S., Yokel R.A. Manganese distribution across the blood-brain barrier. I. Evidence for carrier-mediated influx of manganese citrate as well as manganese and manganese transferrin. Neurotoxicology 2003, 24:3-13.
22. Crowe T.K., Horak F.B. Motor proficiency associated with vestibular deficits in children with hearing impairments. Phys Ther 1988, 68:1493-1499.
23. Davis J.M. Inhalation health risks of manganese: an EPA perspective. Neurotoxicology 1999, 20:511-518.
24. Dietrich K.N. Environmental toxicants. Pediatric neuropsychology 2010, P. 211-264. Guilford, New York. 2nd ed. K.O. Yeates (Ed.).
25. Dorman D.C., Brenneman K.A., McElveen A.M., Lynch S.E., Roberts K.C., Wong B.A. Olfactory transport: a direct route of delivery of inhaled manganese phosphate to the rat brain. J Toxicol Environ Health A 2002, 65(20):1493-1511.
26. Dorman D.C., Struve M.F., Wong B.A., Dye J.A., Robertson I.D. Correlation of brain magnetic resonance imaging changes with pallidal manganese concentrations in rhesus monkeys following subchronic manganese inhalation. Toxicol. Sci 2006, 92:219-227.
27. Eastman R.R., Jursa T.P., Benedetti C., Lucchini R.G., Smith D.R. Hair as a biomarker of environmental manganese exposure. Environ Sci Technol 2013, 47(3):1629-1637.
28. Ellingsen D.G., Konstantinov R., Bast-Pettersen R., Merkurjeva L., Chashchin M., Thomassen Y., et al. A neurobehavioral study of current and former welders exposed to manganese. Neurotoxicology 2008, 29:48-59.
29. Elder A., Gelein R., Silva V., Feikert T., Opanashuk L., Carter J., et al. Translocation of inhaled ultrafine manganese oxide particles to the central nervous system. Environ Health Perspect 2006, 114(8):1172-1178.
30. Environmental Protection Agency (EPA) Reports. Toxic release inventory explorer available; [updated 2012 October 16; cited 2012 February 23] [Internet]. Available from:. http://www.epa.gov/triexplorer/.
31. Environmental Protection Agency (EPA) Reports. Integrated risk information system [updated 2012 August 09; cited 2012 February 23] [Internet]. Available from:. http://www.eps.gov/iris/subst/0373.htm/.
32. Eriksson H., Tedroff J., Thuomas K.A., Aquilonius S.M., Hartvig P., Fasth K.J., et al. Manganese induced brain lesions in Macaca fascicularis as revealed by positron emission tomography and magnetic resonance imaging. Arch Toxicol 1992, 66:403-407.
33. Finley J.W., Penland J.G., Pettit R.E., Davis C.D. Dietary manganese intake and type of lipid do not affect clinical or neuropsychological measures in healthy young women. J Nutr 2003, 133(9):2849-2856.
34. Ganguli M., Lytle M.E., Reynolds M.D., Dodge H.H. Random versus volunteer selection for a community-based study. J Gerontology 1998, 53A(1):M39-M46.
35. Guilarte T.R., McGlothan J., Degaonkar M., Chen M.K., Barker P.B., Syversen T., et al. Evidence for cortical dysfunction and widespread manganese accumulation in the nonhuman primate brain following chronic manganese exposure: a 1H-MRS and MRI study. Toxicol Sci 2006, 94:351-358.
36. Gulson B., Mizon K., Taylor A., Korsch M., Stauber J., Davis J.M., et al. Changes in manganese and lead in the environment and young children associated with the introduction of methylcyclopentadienyl manganese tricarbonyl in gasoline-preliminary results. Environ Res 2006, 100:100-114.
37. Hagiwara S., Nakajima S. Differences in Na and Ca spikes as examined by application of tetrodotoxin, procaine, and manganese ions. J Gen Physiol 1966, 49:793-806.
38. Harkins D.K., Susten A.S. Hair analysis: exploring the state of the science. Environ Health Perspect 2003, 111:576-578.
39. Haynes E.N., Heckel P., Ryan P., Roda S., Leung Y.K., Sebastian K., et al. Environmental manganese exposure in residents living near a ferromanganese refinery in Southeast Ohio: a pilot study. Neurotoxicology 2010, 31:468-474.
40. Haynes E.N., Beidler C., Wittberg R., Meloncon L., Parin M., Kopras E.J., et al. Developing a bidirectional academic-community partnership with an Appalachian American community for environmental health research and risk communication. Environ Health Perspect 2011, 119(10):1364-1372.
41. Haynes E.N., Ryan P., Chen A., Brown D., Roda S., Kuhnell P., Wittberg D., Terrell M., Reponen T. Assessment of personal exposure to manganese in children living near a ferromanganese refinery. Sci Total Environ 2012, 427-428:19-25.
42. Hernández-Bonilla D., Schilmann A., Montes S., Rodríguez-Agudelo Y., Rodríguez-Dozal S., Solís-Vivanco R., et al. Environmental exposure to manganese and motor function of children in Mexico. Neurotoxicology 2011, 32(5):615-621.
43. Kaneda K., Nambu A., Tokuno H., Takada M. Differential processing patterns of motor information via striatopallidal and striatonigral projections. J Neurophysiol 2002, 88:1420-1432.
44. Kincl L.D., Dietrich K.N., Bhattacharya A. Injury trends for adolescents with early childhood lead exposure. J Adol Health 2006, 39(4):604-606.
45. Kim E.A., Cheong H.K., Choi D.S., Sakong J., Ryoo J.W., Park I., et al. Effect of occupational manganese exposure on the central nervous system of welders: 1H magnetic resonance spectroscopy and MRI findings. Neurotoxicology 2007, 28:276-283.
46. Landrigan P.J., Miodovnik A. Children's health and the environment: an overview. Mt Sinai J Med 2011, 78:1-10.
47. Lucchini R., Apostoli P., Perrone C., Placidi D., Albini E., Migliorati P., Peter S., Zacco A. Long-term exposure to 'low levels' of manganese oxides and neurofunctional changes in ferroalloy workers. Neurotoxicology 1999, 20:287-297.
48. Lucchini R.G., Guazzetti S., Zoni S., Donna F., Peter S., Zacco A. Tremor, olfactory and motor changes in Italian adolescents exposed to historical ferromanganese emission. Neurotoxicology 2012, 33(4):687-696.
49. McKelvey W., Gwynn R.C., Jeffrey N., Kass D., Thorpe L.E., Garg R.K., et al. A biomonitoring study of lead, cadmium, and mercury, in the blood of New York City adults. Environ Health Perspect 2007, 115:1435-1441.
50. Menezes-Filho J.A., Bouchard M., Sarcinelli Pde N., Moreira J.C. Manganese exposure and the neuropsychological effect on children and adolescents: a review. Pan Am J Public Health 2009, 26:541-548.
51. Min K., Lee K., Park J., Min J. Lead and cadmium levels and balance and vestibular dysfunction among adult participants in the National Health and Nutrition Examination Survey (NHANES) 1999-2004. Environ Health Perspect 2012, 120:413-417.
52. Murphy K.E., Guthrie W.F., Vetter T.W., Turk G.C., Palmer C.D., Lewis M.E., et al. Comparison of clinical methods with isotope dilution inductively coupled plasma mass spectrometry for the new standard reference material 955c lead in caprine blood. J Anal At Spectrom 2009, 24:1170-1178.
53. Nambu A. Seven problems of the basal ganglia. Curr Opin Neurobiol 2008, 18:595-604.
54. Nasu T., Oosako H. Dantrolene blocks the tonic contractions to carbachol and histamine with smaller effects on the phasic due to release of intracellular Ca2+ in ileal longitudinal muscle. Gen Pharmacol 1995, 26(7):1591-1596.
55. Palmer C.D., Lewis M.E., Geraghty C.M., Barbosa F., Parsons P.J. Determination of lead, cadmium and mercury in blood for assessment of environmental exposure: a comparison between inductively coupled plasma-mass spectrometry and atomic absorption spectrometry. Spect Acta B 2006, 61:980-990.
56. Papavasiliou P.S., Miller S.T., Cotzias G.C. Role of liver in regulating distribution and excretion of manganese. Am J Physiol 1966, 211(1):211-216.
57. Praamsma M.L., Arnason J.G., Parsons P.J. Monitoring Mn in whole blood and urine: a comparison between electrothermal atomic absorption and inorganic mass spectroscopy. J Anal At Spectrom 2011, 26:1224-1232.
58. Praamsma M.L., Jones D.R., Jarrett J.M., Dumas P., Cirtiu C.M., Parsons P.J. A comparison of clinical laboratory data for assigning a consensus value for manganese in a caprine blood reference material. J Anal At Spectrom 2012, 27:1975-1982.
59. Rabin O., Hegedus L., Bourre J.M., Smith Q.R. Rapid brain uptake of manganese(II) across the blood-brain barrier. J Neurochem 1993, 61:509-517.
60. Rodríguez-Agudelo Y., Riojas-Rodríguez H., Ríos C., Rosas I., Sabido Pedraza E., Miranda J., et al. Motor alterations associated with exposure to manganese in the environment in Mexico. Sci Total Environ 2006, 368:542-556.
61. Röllin H., Mathee A., Levin J., Theodorou P., Wewers F. Blood manganese concentrations among first-grade schoolchildren in two South African cities. Environ Res 2005, 97:93-99.
62. Shumway-Cook A., Woollacott M.H. The growth of stability: postural control from a developmental perspective. J Mot Behav 1985, 17:131-147.
63. Smith L.B., Bhattacharya A., Lemasters G., Succop P., Puhala E., Medvedovic M., et al. Effect of chronic low-level exposure to jet fuel on postural balance of U.S. Air Force personnel. J Occup Environ Med 1997, 39:623-632.
64. Standridge J.S., Bhattacharya A., Succop P., Cox C., Haynes E. Effect of chronic low level manganese exposure on postural balance: a pilot study of residents in Southern Ohio. J Occup Environ Med 2008, 50:1421-1429.
65. Takser L., Mergler D., Hellier G., Sahuquillo J., Huel G. Manganese, monoamine metabolite levels at birth, and child psychomotor development. NeuroToxicology 2003, 24(4-5):667-674.
66. Uchino A., Noguchi T., Nomiyama K., Takase Y., Nakazono T., Nojiri J., et al. Manganese accumulation in the brain: MR imaging. Neuroradiology 2007, 49:715-720.
67. Visser J.E., Bloem B.R. Role of the basal ganglia in balance control. Neural Plast 2005, 12:161-174.
68. Wasserman G.A. Water manganese exposure and children's intellectual function in Araihazar, Bangladesh. Environ Health Perspect 2006, 114:124-129.
69. Wallace L., Slonecker T. Ambient air concentrations of fine (PM2.5) manganese in U.S. national parks and in California and Canadian cities: the possible impact of adding MMT to unleaded gasoline. J Air Waste Manag Assoc 1997, 47(6):642-652.
70. Wechsler D. Wechsler abbreviated scale of intelligence 1999, Harcourt Assessment, Inc., San Antonio, TX.
71. Wright R.O., Amarasiriwardena C., Woolf A.D., Jim R., Bellinger D.C. Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site. Neurotoxicology 2006, 27:210-216.
72. Zheng W., Fu S.X., Dydak U., Cowan D.M. Biomarkers of manganese intoxication. Neurotoxicology 2011, 32(1):1-8.
73. Zoni S., Albini E., Lucchini R. Neuropsychological testing for the assessment of manganese neurotoxicity: a review and a proposal. Am J Ind Med 2007, 50(11):812-830.