Sorting and identification of side population cells in the human cervical cancer cell line HeLa

Cancer Cell International

Volumn 14, Issue 1, 2014, Pages

  Qi, Wenjuan ^a   Zhao, Chao ^a   Zhao, Lijun ^a   Liu, Ning ^b   Li, Xiaoping ^a   Yu, Weidong ^a   Wei, Lihui ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^b Haidian Maternal and Child Health Hospital   (China)

Author keywords

Cervical cancer cells; Chemoresistance; Fluorescence activated cell sorting; Radioresistance; Side population cells

Indexed keywords

EID: 84892387901     PISSN: None     EISSN: 14752867     Source Type: Journal    
DOI: 10.1186/1475-2867-14-3     Document Type: Article

References (38)

1. Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature 2001, 414:105-111. 10.1038/35102167, 11689955.
2. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003, 100:3983-3988. 10.1073/pnas.0530291100, 153034, 12629218.
3. Goodell MABK, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 1996, 183:1797-1806. 10.1084/jem.183.4.1797, 2192511, 8666936.
4. Wulf GG, Wang RY, Kuehnle I, Weidner D, Marini F, Brenner MK, et al. A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid 1eukemia. Blood 2001, 98:1166-1173. 10.1182/blood.V98.4.1166, 11493466.
5. Setoguchi T, Taga T, Kondo T. Cancer stem cells persist in many cancer cell lines. Cell Cycle 2004, 3:414-415. 10.4161/cc.3.4.799, 15004528.
6. Chiba T, Kita K, Zheng YW, Yokosuka O, Iwama A, Nakauchi H. Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties. Hepatology 2006, 44:240-251.
7. Hu L, McArthur C, Jaffe RB. Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant. Br J Cancer 2010, 102:1276-1283. 10.1038/sj.bjc.6605626, 2856005, 20354527.
8. Ho MM, Ng AV, Lam S, Hung JY. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res 2007, 67:4827-4833. 10.1158/0008-5472.CAN-06-3557, 17510412.
9. Zhang SN, Huang FT, Huang YJ, Zhong W, Yu Z. Characterization of a cancer stem cell-like side population derived from human pancreatic adenocarcinoma cells. Tumori 2010, 96:985-992.
10. Hadnagy A, Gaboury L, Beaulieu R, Balicki D. SP analysismay be used to identify cancer stem cell populations. Exp Cell Res 2006, 312:3701-3710. 10.1016/j.yexcr.2006.08.030, 17046749.
11. Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK, et al. A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci USA 1998, 95:15665-15670. 10.1073/pnas.95.26.15665, 28101, 9861027.
12. Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ, et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 2001, 7:1028-1034. 10.1038/nm0901-1028, 11533706.
13. Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997, 3:730-737. 10.1038/nm0797-730, 9212098.
14. Kondo T, Setoguchi T, Taga T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci USA 2004, 101:781-786. 10.1073/pnas.0307618100, 321758, 14711994.
15. Haraguchi N, Utsunomiya T, Inoue H, Tanaka F, Mimori K, Barnard GF, et al. Characterization of a side population of cancer cells from human gastrointestinal system. Stem Cells 2006, 24:506-513. 10.1634/stemcells.2005-0282, 16239320.
16. Hischmann-jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, et al. A distinct"side population" of cells with high drug efflux capacity in huamn tumor cells. Proc Natl Acad Sci USA 2004, 101:142228-142233.
17. Huang D, Gao Q, Guo L, Zhang C, Jiang W, Li H, et al. Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines. Stem Cells Dev 2009, 18:465-473. 10.1089/scd.2008.0033, 18680391.
18. Challen GA, Little MH. A Side Order of Stem Cells: The SP Phenotype. Stem Cells 2006, 24:3-12. 10.1634/stemcells.2005-0116, 16449630.
19. Yannamoto S, Kawasaki G, Yamada S, Yoshitomi I, Kawano T, Yonezawa H, et al. Isolation and characterization of cancer stem-like side population cells in human oral cancer cells. Oral Oncol 2011, 47:855-860. 10.1016/j.oraloncology.2011.06.501, 21757396.
20. Schmuck R, Warneke V, Behrens HM, Simon E, Weichert W, Rocken C. Genotypic and phenotypic characterization of side population of gastric cancer cell lines. Am J Pathol 2011, 178:1792-1804. 10.1016/j.ajpath.2010.12.043, 3078445, 21435459.
21. Doyle LA, Ross DD. Multidrug resistance mediated by the breast cancer resistance protein BCRP(ABCG2). Oncogene 2003, 22:7340-7358. 10.1038/sj.onc.1206938, 14576842.
22. Hu C, Li H, Li J, Zhu Z, Yin S, Hao X, et al. Analysis of ABCG2 expression and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation by Akt signaling. Carcinogenesis 2008, 29:2289-2297. 10.1093/carcin/bgn223, 18820285.
23. Moserle L, Ghisi M, Amadori A, Indraccolo S. Side population and cancer stem cell: therapeutic implications. Cancer letters 2010, 288:1-9. 10.1016/j.canlet.2009.05.020, 19523754.
24. Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 2007, 1:555-567. 10.1016/j.stem.2007.08.014, 2423808, 18371393.
25. Jiang F, Qiu Q, Khanna A, Todd NW, Deepak J, Xing L, Wang H, et al. Aldehyde dehydrogenase 1is a tumor stem cell-associated marker in lung cancer. Mol Cancer Res 2009, 7:330-338. 10.1158/1541-7786.MCR-08-0393, 19276181.
26. Kim H, Lapointe J, Kaygusuz G, Ong DE, Li C, Van De Rijn M, et al. The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer. Cancer Res 2005, 65:8118-8124. 10.1158/0008-5472.CAN-04-4562, 16166285.
27. Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, et al. Identification of pancreatic cancer stem cells. Cancer Res 2007, 6:1030-1037.
28. Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, et al. A distinct " side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci USA 2004, 101:14228-14233. 10.1073/pnas.0400067101, 521140, 15381773.
29. Chiba T, Kita K, Zheng YW, Yokosuka O, Saisho H, Iwama A, et al. Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties. Hepatology 2006, 44:240-251.
30. Shi Y, Fu X, Hua Y, Han Y, Lu Y, Wang J. The side population in human lung cancer cell line NCI-H460 is enriched in stem-like cancer cells. PLoS One 2012, 7:1-8.
31. Wang J, Guo LP, Chen LZ, Zeng YX, Lu SH. Identification of cancer stem cell-like side population cells in human Nasopharygeal carcinoma cell line. Cancer Res 2007, 67:3716-3724. 10.1158/0008-5472.CAN-06-4343, 17440084.
32. Pan J, Zhang Q, Wang Y, You M. 26S proteasome activity is down-regulated in lung cancer stem-like cells propagated in vitro. Plos One 2010, 5:1-9.
33. Platet N, Mayol J-F, Berger F, Herodin F, Wion D. Fluctuation of the SP/non-SP phenotype in the C6 glioma cell line. FEBS Letters 2007, 581:1435-1440. 10.1016/j.febslet.2007.02.071, 17362939.
34. Enokizono J, Kusuhara H, Sugiyama Y. Involvement of breast cancer resistance protein(BCRP/ABCG2) in the biliary excretion and intestinal efflux of troglitazone sulfate, the major metabolite of troglitazone with a cholestatic effect. Drug Metab Dispos 2007, 35:209-214.
35. Xia P, Gou WF, Wang JJ, Niu ZF, Chen S, Takano Y, et al. Distinct radiosensitivity of lung carcinoma stem-like side population and main population cells. Cancer Biother Radiopharm 2013, 28:471-478. 10.1089/cbr.2012.1388, 23514663.
36. Liang K, Jin W, Knuefermann C, Schmidt M, Mills GB, Ang KK, et al. Targeting the phosphatidylinositol 3-kinase/Akt pathway for enhancing breast cancer cells toradiotherapy. Mol Cancer Ther 2003, 2:353-360.
37. Zhang T, Cui GB, Zhang J, Zhang F, Zhou YA, Jiang T, et al. Inhibition of PI3 kinases enhances the sensitivity of non-small cell lung cancer cells to ionizing radiation. Oncol Rep 2010, 24:1683-1689.
38. Fujiwara K, Iwado E, Mills GB, Sawaya R, Kondo S, Kondo Y. Akt inhibitor shows anticancer and radiosensitizing effects in maligant glioma cells by inducingautohagy. Int J Oncol 2007, 31:753-760.