Inhibition of PI3 kinases enhances the sensitivity of non-small cell lung cancer cells to ionizing radiation

Oncology Reports

Volumn 24, Issue 6, 2010, Pages 1683-1689

  Zhang, Tao ^a   Cui, Guang Bin ^a   Zhang, Jian ^b   Zhang, Feng ^c   Zhou, Yong A N ^a   Jiang, Tao ^a   Li, Xiao Fei ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cell cycle; DNA PKcs; PI3K; Radiosensitivity; Wortmannin

Indexed keywords

ACTIN; CASPASE 3; CYTOCHROME C; DNA DEPENDENT PROTEIN KINASE; GAMMA HISTONE H2AX; HISTONE H2AX; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG; WORTMANNIN; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; HUMAN; HUMAN CELL; IONIZING RADIATION; LUNG NON SMALL CELL CANCER; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN FAMILY; RADIOSENSITIVITY;

ANDROSTADIENES; APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; DNA BREAKS, DOUBLE-STRANDED; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HUMANS; LUNG NEOPLASMS; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; RADIATION TOLERANCE; RADIATION, IONIZING; RADIATION-SENSITIZING AGENTS; TUMOR CELLS, CULTURED; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 78649432051     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00001034     Document Type: Article

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