-
1
-
-
84867754193
-
Irritable bowel syndrome: Diagnosis and pathogenesis
-
El-Salhy M. Irritable bowel syndrome: Diagnosis and pathogenesis. WJG 2012; 18: 5151-5163
-
(2012)
WJG
, vol.18
, pp. 5151-5163
-
-
El-Salhy, M.1
-
2
-
-
84883588093
-
Irritable bowel syndrome: The role of gut neuroendocrine peptides
-
El-Salhy M, Seim I, Chopin L, et al. Irritable bowel syndrome: The role of gut neuroendocrine peptides. Front Biosci (Elite Ed) 2012; 4: 2783-2800
-
(2012)
Front Biosci (Elite Ed
, vol.4
, pp. 2783-2800
-
-
El-Salhy, M.1
Seim, I.2
Chopin, L.3
-
3
-
-
84859888900
-
A global perspective on irritable bowel syndrome: A consensus statement of the world gastroenterology organisation summit task force on irritable bowel syndrome
-
Quigley EM, Abdel-Hamid H, Barbara G, et al. A global perspective on irritable bowel syndrome: A consensus statement of the World Gastroenterology Organisation Summit Task Force on irritable bowel syndrome. J Clin Gastroenterol 2012; 46: 356-366
-
(2012)
J Clin Gastroenterol
, vol.46
, pp. 356-366
-
-
Quigley, E.M.1
Abdel-Hamid, H.2
Barbara, G.3
-
4
-
-
42249114703
-
Clinical practice. Irritable bowel syndrome
-
Mayer EA. Clinical practice. Irritable bowel syndrome. N Engl J Med 2008; 358: 1692-1699
-
(2008)
N Engl J Med
, vol.358
, pp. 1692-1699
-
-
Mayer, E.A.1
-
5
-
-
79951569700
-
The effect of irritable bowel syndrome on healthrelated quality of life and healthcare expenditures
-
Agarwal N, Spiegel BM. The effect of irritable bowel syndrome on healthrelated quality of life and healthcare expenditures. Gastroenterol Clin North Am 2011; 40: 11-19
-
(2011)
Gastroenterol Clin North Am
, vol.40
, pp. 11-19
-
-
Agarwal, N.1
Spiegel, B.M.2
-
6
-
-
68349141680
-
Developing valid and reliable health utilities in irritable bowel syndrome: Results from the ibs proof cohort
-
Spiegel B, Harris L, Lucak S, et al. Developing valid and reliable health utilities in irritable bowel syndrome: Results from the IBS PROOF Cohort. Am J Gastroenterol 2009; 104: 1984-1991
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 1984-1991
-
-
Spiegel, B.1
Harris, L.2
Lucak, S.3
-
7
-
-
0344413667
-
Utilization patterns and net direct medical cost to medicaid of irritable bowel syndrome
-
Martin BC, Ganguly R, Pannicker S, et al. Utilization patterns and net direct medical cost to Medicaid of irritable bowel syndrome. Curr Med Res Opin 2003; 19: 771-780
-
(2003)
Curr Med Res Opin
, vol.19
, pp. 771-780
-
-
Martin, B.C.1
Ganguly, R.2
Pannicker, S.3
-
8
-
-
0242584898
-
The economic consequences of irritable bowel syndrome: A US employer perspective
-
Leong SA, Barghout V, Birnbaum HG, et al. The economic consequences of irritable bowel syndrome: A US employer perspective. Arch Intern Med 2003; 163: 929-935
-
(2003)
Arch Intern Med
, vol.163
, pp. 929-935
-
-
Leong, S.A.1
Barghout, V.2
Birnbaum, H.G.3
-
9
-
-
0037344032
-
Irritable bowel syndrome, healthcare use, and costs: A U.S. Managed care perspective
-
Longstreth GF, Wilson A, Knight K, et al. Irritable bowel syndrome, healthcare use, and costs: A U.S. managed care perspective. Am J Gastroenterol 2003; 98: 600-607
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 600-607
-
-
Longstreth, G.F.1
Wilson, A.2
Knight, K.3
-
10
-
-
0034012726
-
Economic burden of irritable bowel syndrome proposed strategies to control expenditures
-
Camilleri M, Williams DE. Economic burden of irritable bowel syndrome. Proposed strategies to control expenditures. Pharmacoeconomics 2000; 17: 331-338
-
(2000)
Pharmacoeconomics
, vol.17
, pp. 331-338
-
-
Camilleri, M.1
Williams, D.E.2
-
12
-
-
2342550581
-
Are there alterations of neuroendocrine and cellular immune responses to nutrients in women with irritable bowel syndrome
-
Elsenbruch S, Holtmann G, Oezcan D, et al. Are there alterations of neuroendocrine and cellular immune responses to nutrients in women with irritable bowel syndrome? Am J Gastroenterol 2004; 99: 703-710
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 703-710
-
-
Elsenbruch, S.1
Holtmann, G.2
Oezcan, D.3
-
14
-
-
32044464304
-
Neuroendocrine and neuroimmune markers in IBS: Pathophysiological role or epiphenomenon
-
Chang L. Neuroendocrine and neuroimmune markers in IBS: Pathophysiological role or epiphenomenoñGastroenterology 2006; 130: 596-600
-
(2006)
Gastroenterology
, vol.130
, pp. 596-600
-
-
Chang, L.1
-
15
-
-
84861167356
-
Irritable bowel syndrome: Methods, mechanisms, and pathophysiology neural and neuro-immune mechanisms of visceral hypersensitivity in irritable bowel syndrome
-
Feng B, La JH, Schwartz ES, Gebhart GF. Irritable bowel syndrome: Methods, mechanisms, and pathophysiology. Neural and neuro-immune mechanisms of visceral hypersensitivity in irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol 2012; 302: G1085-G1098
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
-
-
Feng, B.1
La, J.H.2
Schwartz, E.S.3
Gebhart, G.F.4
-
16
-
-
55649112489
-
Serotonergic agents and the irritable bowel syndrome: What goes wrong
-
Spiller R. Serotonergic agents and the irritable bowel syndrome: What goes wrong? Curr Opin Pharmacol 2008; 8: 709-714
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 709-714
-
-
Spiller, R.1
-
17
-
-
33744949904
-
Enteroendocrine cell counts correlate with visceral hypersensitivity in patients with diarrhoea-predominant irritable bowel syndrome
-
Park JH, Rhee PL, Kim G, et al. Enteroendocrine cell counts correlate with visceral hypersensitivity in patients with diarrhoea-predominant irritable bowel syndrome. Neurogastroenterol Motil 2006; 18: 539-546
-
(2006)
Neurogastroenterol Motil
, vol.18
, pp. 539-546
-
-
Park, J.H.1
Rhee, P.L.2
Kim, G.3
-
18
-
-
84867828617
-
Peripheral mechanisms in irritable bowel syndrome
-
Camilleri M. Peripheral mechanisms in irritable bowel syndrome. N Engl J Med 2012; 367: 1626-1635
-
(2012)
N Engl J Med
, vol.367
, pp. 1626-1635
-
-
Camilleri, M.1
-
19
-
-
80052155410
-
Management of irritable bowel syndrome (IBS) in adults: Conventional and complementary/alternative approaches
-
Yoon SL, Grundmann O, Koepp L, Farrell L. Management of irritable bowel syndrome (IBS) in adults: Conventional and complementary/alternative approaches. Altern Med Rev 2011; 16: 134-151
-
(2011)
Altern Med Rev
, vol.16
, pp. 134-151
-
-
Yoon, S.L.1
Grundmann, O.2
Koepp, L.3
Farrell, L.4
-
20
-
-
67649537590
-
An evidence-based position statement on the management of irritable bowel syndrome
-
Brandt LJ, Chey WD, Foxx-Orenstein AE, et al. An evidence-based position statement on the management of irritable bowel syndrome. Am J Gastroenterol 2009; 104 (Suppl 1): S1-S35
-
(2009)
Am J Gastroenterol
, vol.104
, Issue.SUPPL. 1
-
-
Brandt, L.J.1
Chey, W.D.2
Foxx-Orenstein, A.E.3
-
21
-
-
0027981172
-
Antidepressant therapy in 138 patients with irritable bowel syndrome: A five-year clinical experience
-
Clouse RE, Lustman PJ, Geisman RA, Alpers DH. Antidepressant therapy in 138 patients with irritable bowel syndrome: A five-year clinical experience. Alimen Pharmacol Ther 1994; 8: 409-416
-
(1994)
Alimen Pharmacol Ther
, vol.8
, pp. 409-416
-
-
Clouse, R.E.1
Lustman, P.J.2
Geisman, R.A.3
Alpers, D.H.4
-
22
-
-
84871926401
-
5-Hydroxytryptamine (serotonin) in the gastrointestinal tract
-
Gershon MD. 5-Hydroxytryptamine (serotonin) in the gastrointestinal tract. Curr Opin Endocrinol Diab Obes 2013; 20: 14-21
-
(2013)
Curr Opin Endocrinol Diab Obes
, vol.20
, pp. 14-21
-
-
Gershon, M.D.1
-
23
-
-
33846347644
-
The serotonin signaling system: From basic understanding to drug development for functional GI disorders
-
Gershon MD, Tack J. The serotonin signaling system: From basic understanding to drug development for functional GI disorders. Gastroenterology 2007; 132: 397-414
-
(2007)
Gastroenterology
, vol.132
, pp. 397-414
-
-
Gershon, M.D.1
Tack, J.2
-
24
-
-
78650835708
-
Gastrointestinal regulatory peptides
-
Weber HC. Gastrointestinal regulatory peptides. Curr Opin Endocrinol Diab Obes 2011; 18: 33-34
-
(2011)
Curr Opin Endocrinol Diab Obes
, vol.18
, pp. 33-34
-
-
Weber, H.C.1
-
25
-
-
84880860326
-
Emerging receptor target in the pharmacotherapy of irritable bowel syndrome with constipation
-
Blackshaw LA, Brierley SM. Emerging receptor target in the pharmacotherapy of irritable bowel syndrome with constipation. Expert Rev Gastroenterol Hepatol 2013; 7: 15-19
-
(2013)
Expert Rev Gastroenterol Hepatol
, vol.7
, pp. 15-19
-
-
Blackshaw, L.A.1
Brierley, S.M.2
-
26
-
-
71549121350
-
Review article: New receptor targets for medical therapy in irritable bowel syndrome
-
Camilleri M. Review article: New receptor targets for medical therapy in irritable bowel syndrome. Alimen Pharmacol Ther 2010; 31: 35-46
-
(2010)
Alimen Pharmacol Ther
, vol.31
, pp. 35-46
-
-
Camilleri, M.1
-
27
-
-
67650455908
-
Efficacy of 5-HT3 antagonists and 5-HT4 agonists in irritable bowel syndrome: Systematic review and meta-Analysis
-
Ford AC, Brandt LJ, Young C, et al. Efficacy of 5-HT3 antagonists and 5-HT4 agonists in irritable bowel syndrome: Systematic review and meta-Analysis. Am J Gastroenterol 2009; 104: 1831-1843
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 1831-1843
-
-
Ford, A.C.1
Brandt, L.J.2
Young, C.3
-
28
-
-
84872235011
-
A review of the clinical efficacy of linaclotide in irritable bowel syndrome with constipation
-
Johnston JM, Shiff SJ, Quigley EM. A review of the clinical efficacy of linaclotide in irritable bowel syndrome with constipation. Curr Med Res Opin 2013; 29: 149-160
-
(2013)
Curr Med Res Opin
, vol.29
, pp. 149-160
-
-
Johnston, J.M.1
Shiff, S.J.2
Quigley, E.M.3
-
29
-
-
65549109893
-
Lubiprostone: Chronic constipation and irritable bowel syndrome with constipation
-
Lacy BE, Chey WD. Lubiprostone: Chronic constipation and irritable bowel syndrome with constipation. Expert Opin Pharmacother 2009; 10: 143-152
-
(2009)
Expert Opin Pharmacother
, vol.10
, pp. 143-152
-
-
Lacy, B.E.1
Chey, W.D.2
-
30
-
-
79953315976
-
Treatment of irritable bowel syndrome: Beyond fiber and antispasmodic agents
-
Sainsbury A, Ford AC. Treatment of irritable bowel syndrome: Beyond fiber and antispasmodic agents. Ther Adv Gastroenterol 2011; 4: 115-127
-
(2011)
Ther Adv Gastroenterol
, vol.4
, pp. 115-127
-
-
Sainsbury, A.1
Ford, A.C.2
-
31
-
-
79751514491
-
Ibs in 2010: Advances in pathophysiology, diagnosis and treatment nature reviews
-
Ford AC, Talley NJ. IBS in 2010: Advances in pathophysiology, diagnosis and treatment. Nature reviews. Gastroenterol Hepatol 2011; 8: 76-78
-
(2011)
Gastroenterol Hepatol
, vol.8
, pp. 76-78
-
-
Ford, A.C.1
Talley, N.J.2
-
32
-
-
0035894575
-
Serotoninergic neuroenteric modulators
-
Talley NJ. Serotoninergic neuroenteric modulators. Lancet 2001; 358: 2061-2068
-
(2001)
Lancet
, vol.358
, pp. 2061-2068
-
-
Talley, N.J.1
-
33
-
-
0031959979
-
Actions of the 5-hydroxytryptamine 1 receptor agonist sumatriptan on interdigestive gastrointestinal motility in man
-
Tack J, Coulie B, Wilmer A, et al. Actions of the 5-hydroxytryptamine 1 receptor agonist sumatriptan on interdigestive gastrointestinal motility in man. Gut 1998; 42: 36-41
-
(1998)
Gut
, vol.42
, pp. 36-41
-
-
Tack, J.1
Coulie, B.2
Wilmer, A.3
-
34
-
-
42749097353
-
Effects of 5-hydroxytryptamine (serotonin) type 3 antagonists on symptomrelief and constipation in nonconstipated irritable bowel syndrome: A systematic review and meta-Analysis of randomized controlled trials
-
Andresen V, Montori VM, Keller J, et al. Effects of 5-hydroxytryptamine (serotonin) type 3 antagonists on symptomrelief and constipation in nonconstipated irritable bowel syndrome: A systematic review and meta-Analysis of randomized controlled trials. Clin Gastroenterol Hepatol 2008; 6: 545-555
-
(2008)
Clin Gastroenterol Hepatol
, vol.6
, pp. 545-555
-
-
Andresen, V.1
Montori, V.M.2
Keller, J.3
-
35
-
-
79953727524
-
Targeting the 5-HT(3) receptor in the treatment of irritable bowel syndrome
-
Spiller RC. Targeting the 5-HT(3) receptor in the treatment of irritable bowel syndrome. Curr Opin Pharmacol 2011; 11: 68-74
-
(2011)
Curr Opin Pharmacol
, vol.11
, pp. 68-74
-
-
Spiller, R.C.1
-
36
-
-
77951677635
-
Alosetron for severe diarrhea-predominant irritable bowel syndrome: Safety and efficacy in perspective
-
Lewis JH. Alosetron for severe diarrhea-predominant irritable bowel syndrome: Safety and efficacy in perspective. Expert Rev Gastroenterol Hepatol 2010; 4: 13-29
-
(2010)
Expert Rev Gastroenterol Hepatol
, vol.4
, pp. 13-29
-
-
Lewis, J.H.1
-
37
-
-
16444362290
-
The effects of the 5-HT3 antagonist, alosetron, on brain serotonin synthesis in patients with irritable bowel syndrome
-
Nakai A, Diksic M, Kumakura Y, et al. The effects of the 5-HT3 antagonist, alosetron, on brain serotonin synthesis in patients with irritable bowel syndrome. Neurogastroenterol Motil 2005; 17: 212-221
-
(2005)
Neurogastroenterol Motil
, vol.17
, pp. 212-221
-
-
Nakai, A.1
Diksic, M.2
Kumakura, Y.3
-
38
-
-
0037295146
-
Efficacy of alosetron in irritable bowel syndrome: A meta-Analysis of randomized controlled trials
-
Cremonini F, Delgado-Aros S, Camilleri M. Efficacy of alosetron in irritable bowel syndrome: A meta-Analysis of randomized controlled trials. Neurogastroenterol Motil 2003; 15: 79-86
-
(2003)
Neurogastroenterol Motil
, vol.15
, pp. 79-86
-
-
Cremonini, F.1
Delgado-Aros, S.2
Camilleri, M.3
-
40
-
-
79958855229
-
The risk of ischaemic colitis in irritable bowel syndrome patients treated with serotonergic therapies
-
Lewis JH. The risk of ischaemic colitis in irritable bowel syndrome patients treated with serotonergic therapies. Drug Saf 2011; 34: 545-565
-
(2011)
Drug Saf
, vol.34
, pp. 545-565
-
-
Lewis, J.H.1
-
41
-
-
33646441324
-
Incidence of ischemic colitis and serious complications of constipation among patients using alosetron: Systematic review of clinical trials and postmarketing surveillance data
-
Chang L, Chey WD, Harris L, et al. Incidence of ischemic colitis and serious complications of constipation among patients using alosetron: Systematic review of clinical trials and postmarketing surveillance data. Am J Gastroenterol 2006; 101: 1069-1079
-
(2006)
Am J Gastroenterol
, vol.101
, pp. 1069-1079
-
-
Chang, L.1
Chey, W.D.2
Harris, L.3
-
42
-
-
84864653374
-
Randomised clinical trial: Alosetron improves quality of life and reduces restriction of daily activities in women with severe diarrhoea-predominant IBS
-
Cremonini F, Nicandro JP, Atkinson V, et al. Randomised clinical trial: Alosetron improves quality of life and reduces restriction of daily activities in women with severe diarrhoea-predominant IBS. Alimen Pharmacol Ther 2012; 36: 437-448
-
(2012)
Alimen Pharmacol Ther
, vol.36
, pp. 437-448
-
-
Cremonini, F.1
Nicandro, J.P.2
Atkinson, V.3
-
44
-
-
33846794803
-
Tegaserod for constipation-predominant irritable bowel syndrome
-
Kale-Pradhan PB, Wilhelm SM. Tegaserod for constipation-predominant irritable bowel syndrome. Pharmacotherapy 2007; 27: 267-277
-
(2007)
Pharmacotherapy
, vol.27
, pp. 267-277
-
-
Kale-Pradhan, P.B.1
Wilhelm, S.M.2
-
45
-
-
8544257356
-
Review of tegaserod in the treatment of irritable bowel syndrome
-
Patel S, Berrada D, Lembo A. Review of tegaserod in the treatment of irritable bowel syndrome. Expert Opin Pharmacother 2004; 5: 2369-2379
-
(2004)
Expert Opin Pharmacother
, vol.5
, pp. 2369-2379
-
-
Patel, S.1
Berrada, D.2
Lembo, A.3
-
47
-
-
34250007918
-
Desperately seeking serotonin a commentary on the withdrawal of tegaserod and the state of drug development for functional and motility disorders
-
Pasricha PJ. Desperately seeking serotonin. A commentary on the withdrawal of tegaserod and the state of drug development for functional and motility disorders. Gastroenterology 2007; 132: 2287-2290
-
(2007)
Gastroenterology
, vol.132
, pp. 2287-2290
-
-
Pasricha, P.J.1
-
48
-
-
84892373837
-
-
accessed 8 November 2013
-
http: //www.accessdata.fda.gov/drugsatfda-docs/label/2012/ 021908s010lbl.pdf [accessed 8 November 2013
-
-
-
-
49
-
-
33745798874
-
-
Lubiprostone (amitiza) for chronic constipation
-
Lubiprostone (amitiza) for chronic constipation. Med Lett Drugs Ther 2006; 48: 47-48
-
(2006)
Med Lett Drugs Ther
, vol.48
, pp. 47-48
-
-
-
50
-
-
22244449305
-
-
Review PubMed PMID: 15991886 Drugs R D.
-
Lubiprostone: RU 0211, SPI 0211. Drugs R D. 2005;6(4): 245-8. Review. PubMed PMID: 15991886
-
(2005)
Lubiprostone: RU 0211 SPI 0211
, vol.6
, Issue.4
, pp. 245-248
-
-
-
51
-
-
58149103805
-
Clinical trial: Lubiprostone in patients with constipation-Associated irritable bowel syndrome-results of two randomized, placebo-controlled studies
-
Drossman DA, Chey WD, Johanson JF, et al. Clinical trial: Lubiprostone in patients with constipation-Associated irritable bowel syndrome-results of two randomized, placebo-controlled studies. Alimen Pharmacol Ther 2009; 29: 329-341
-
(2009)
Alimen Pharmacol Ther
, vol.29
, pp. 329-341
-
-
Drossman, D.A.1
Chey, W.D.2
Johanson, J.F.3
-
52
-
-
34248595894
-
Lubiprostone, a locally acting chloride channel activator, in adult patients with chronic constipation: A double-blind, placebo-controlled, dose-ranging study to evaluate efficacy and safety
-
Johanson JF, Ueno R. Lubiprostone, a locally acting chloride channel activator, in adult patients with chronic constipation: A double-blind, placebo-controlled, dose-ranging study to evaluate efficacy and safety. Alimen Pharmacol Ther 2007; 25: 1351-1361
-
(2007)
Alimen Pharmacol Ther
, vol.25
, pp. 1351-1361
-
-
Johanson, J.F.1
Ueno, R.2
-
53
-
-
79955897225
-
Efficacy and safety of oral lubiprostone in constipated patients with or without irritable bowel syndrome: A randomized, placebo-controlled and dose-finding study
-
544-e205
-
Fukudo S, Hongo M, Kaneko H, Ueno R. Efficacy and safety of oral lubiprostone in constipated patients with or without irritable bowel syndrome: A randomized, placebo-controlled and dose-finding study. Neurogastroenterol Motil 2011; 23: 544-e205
-
(2011)
Neurogastroenterol Motil
, vol.23
-
-
Fukudo, S.1
Hongo, M.2
Kaneko, H.3
Ueno, R.4
-
54
-
-
84856707088
-
Safety and patient outcomes with lubiprostone for up to 52 weeks in patients with irritable bowel syndrome with constipation
-
Chey WD, Drossman DA, Johanson JF, et al. Safety and patient outcomes with lubiprostone for up to 52 weeks in patients with irritable bowel syndrome with constipation. Alimen Pharmacol Ther 2012; 35: 587-599
-
(2012)
Alimen Pharmacol Ther
, vol.35
, pp. 587-599
-
-
Chey, W.D.1
Drossman, D.A.2
Johanson, J.F.3
-
55
-
-
84894543194
-
An open-label, multicenter, safety and effectiveness study of lubiprostone for the treatment of functional constipation in children
-
Epub ahead of print]. PubMed PMID: 24048162
-
Hyman PE, Di Lorenzo C, Prestridge LL, et al. An open-label, multicenter, safety and effectiveness study of lubiprostone for the treatment of functional constipation in children. J Pediatr Gastroenterol Nutrition 2013. [Epub ahead of print]. PubMed PMID: 24048162
-
(2013)
J Pediatr Gastroenterol Nutrition
-
-
Hyman, P.E.1
Di Lorenzo, C.2
Prestridge, L.L.3
-
56
-
-
80052863525
-
Lubiprostone does not influence visceral pain thresholds in patients with irritable bowel syndrome
-
Whitehead WE, Palsson OS, Gangarosa L, et al. Lubiprostone does not influence visceral pain thresholds in patients with irritable bowel syndrome. Neurogastroenterol Motil 2011; 23: 944-e400
-
(2011)
Neurogastroenterol Motil
, vol.23
-
-
Whitehead, W.E.1
Palsson, O.S.2
Gangarosa, L.3
-
57
-
-
84860379170
-
Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors
-
Cuppoletti J, Blikslager AT, Chakrabarti J, et al. Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors. BMC Pharmacol 2012; 12: 3
-
(2012)
BMC Pharmacol
, vol.12
, pp. 3
-
-
Cuppoletti, J.1
Blikslager, A.T.2
Chakrabarti, J.3
-
58
-
-
84873654410
-
Lubiprostone induced ischemic colitis
-
Sherid M, Sifuentes H, Samo S, et al. Lubiprostone induced ischemic colitis. WJG 2013; 19: 299-303
-
(2013)
WJG
, vol.19
, pp. 299-303
-
-
Sherid, M.1
Sifuentes, H.2
Samo, S.3
-
59
-
-
84876669771
-
Lubiprostone decreases mouse colonic inner mucus layer thickness and alters intestinal microbiota
-
Musch MW, Wang Y, Claud EC, Chang EB. Lubiprostone decreases mouse colonic inner mucus layer thickness and alters intestinal microbiota. Dig Dis Sci 2013; 58: 668-677
-
(2013)
Dig Dis Sci
, vol.58
, pp. 668-677
-
-
Musch, M.W.1
Wang, Y.2
Claud, E.C.3
Chang, E.B.4
-
60
-
-
84865498099
-
Safety evaluation of lubiprostone in the treatment of constipation and irritable bowel syndrome
-
Chamberlain SM, Rao SS. Safety evaluation of lubiprostone in the treatment of constipation and irritable bowel syndrome. Expert Opin Drug Saf 2012; 11: 841-850
-
(2012)
Expert Opin Drug Saf
, vol.11
, pp. 841-850
-
-
Chamberlain, S.M.1
Rao, S.S.2
-
61
-
-
84872821705
-
-
Linaclotide (Linzess) for constipation. PubMed PMID: 23183319
-
Linaclotide (Linzess) for constipation. Med Letter Drugs Ther 2012; 54: 91-92; PubMed PMID: 23183319
-
(2012)
Med Letter Drugs Ther
, vol.54
, pp. 91-92
-
-
-
62
-
-
77249162216
-
Taking a lesson from microbial diarrheagenesis in the management of chronic constipation
-
Bharucha AE, Waldman SA. Taking a lesson from microbial diarrheagenesis in the management of chronic constipation. Gastroenterology 2010; 138: 813-817
-
(2010)
Gastroenterology
, vol.138
, pp. 813-817
-
-
Bharucha, A.E.1
Waldman, S.A.2
-
63
-
-
84870565183
-
Guanylate cyclase-C receptor activation: Unexpected biology
-
Brierley SM. Guanylate cyclase-C receptor activation: Unexpected biology. Curr Opin Pharmacol 2012; 12: 632-640
-
(2012)
Curr Opin Pharmacol
, vol.12
, pp. 632-640
-
-
Brierley, S.M.1
-
64
-
-
78049283798
-
Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit
-
Busby RW, Bryant AP, Bartolini WP, et al. Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit. Eur J Pharmacol 2010; 649: 328-335
-
(2010)
Eur J Pharmacol
, vol.649
, pp. 328-335
-
-
Busby, R.W.1
Bryant, A.P.2
Bartolini, W.P.3
-
65
-
-
84871682733
-
Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation
-
Busby RW, Kessler MM, Bartolini WP, et al. Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation. J Pharmacol Exp Ther 2013; 344: 196-206
-
(2013)
J Pharmacol Exp Ther
, vol.344
, pp. 196-206
-
-
Busby, R.W.1
Kessler, M.M.2
Bartolini, W.P.3
-
66
-
-
34548500315
-
Effect of 5 days linaclotide on transit and bowel function in females with constipation-predominant irritable bowel syndrome
-
Andresen V, Camilleri M, Busciglio IA, et al. Effect of 5 days linaclotide on transit and bowel function in females with constipation- predominant irritable bowel syndrome. Gastroenterology 2007; 133: 761-768
-
(2007)
Gastroenterology
, vol.133
, pp. 761-768
-
-
Andresen, V.1
Camilleri, M.2
Busciglio, I.A.3
-
67
-
-
78649690668
-
Linaclotide improves abdominal pain and bowel habits in a phase IIb study of patients with irritable bowel syndrome with constipation
-
e1872
-
Johnston JM, Kurtz CB, Macdougall JE, et al. Linaclotide improves abdominal pain and bowel habits in a phase IIb study of patients with irritable bowel syndrome with constipation. Gastroenterology 2010; 139: 1877-1886 e1872
-
(2010)
Gastroenterology
, vol.139
, pp. 1877-1886
-
-
Johnston, J.M.1
Kurtz, C.B.2
Macdougall, J.E.3
-
68
-
-
80051640525
-
Two randomized trials of linaclotide for chronic constipation
-
Lembo AJ, Schneier HA, Shiff SJ, et al. Two randomized trials of linaclotide for chronic constipation. N Engl J Med 2011; 365: 527-536
-
(2011)
N Engl J Med
, vol.365
, pp. 527-536
-
-
Lembo, A.J.1
Schneier, H.A.2
Shiff, S.J.3
-
69
-
-
84869493876
-
A 12-week, randomized, controlled trial with a 4-week randomized withdrawal period to evaluate the efficacy and safety of linaclotide in irritable bowel syndrome with constipation
-
Rao S, Lembo AJ, Shiff SJ, et al. A 12-week, randomized, controlled trial with a 4-week randomized withdrawal period to evaluate the efficacy and safety of linaclotide in irritable bowel syndrome with constipation. Am J Gastroenterol 2012; 107: 1714-1724
-
(2012)
Am J Gastroenterol
, vol.107
, pp. 1714-1724
-
-
Rao, S.1
Lembo, A.J.2
Shiff, S.J.3
-
70
-
-
84869491248
-
Linaclotide for irritable bowel syndrome with constipation: A 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety
-
Chey WD, Lembo AJ, Lavins BJ, et al. Linaclotide for irritable bowel syndrome with constipation: A 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety. Am J Gastroenterol 2012; 107: 1702-1712
-
(2012)
Am J Gastroenterol
, vol.107
, pp. 1702-1712
-
-
Chey, W.D.1
Lembo, A.J.2
Lavins, B.J.3
-
71
-
-
84892366820
-
Effect of linaclotide on severe abdominal symptoms in patients with irritable bowel syndrome with constipation
-
Rao SS, Quigley EM, Shiff SJ, et al. Effect of linaclotide on severe abdominal symptoms in patients with irritable bowel syndrome with constipation. Clin Gastroenterol Hepatol 2013; 11: 1984-1092
-
(2013)
Clin Gastroenterol Hepatol
, vol.11
, pp. 1984-1092
-
-
Rao, S.S.1
Quigley, E.M.2
Shiff, S.J.3
-
72
-
-
84870601331
-
Randomised clinical trials: Linaclotide phase 3 studies in ibs-c-A prespecified further analysis based on european medicines agency-specified endpoints
-
Quigley EM, Tack J, Chey WD, et al. Randomised clinical trials: Linaclotide phase 3 studies in IBS-C-A prespecified further analysis based on European Medicines Agency-specified endpoints. Alimen Pharmacol Ther 2013; 37: 49-61
-
(2013)
Alimen Pharmacol Ther
, vol.37
, pp. 49-61
-
-
Quigley, E.M.1
Tack, J.2
Chey, W.D.3
-
73
-
-
84882775844
-
Effects of linaclotide in patients with irritable bowel syndrome with constipation or chronic constipation: A metaanalysis
-
1083
-
Videlock EJ, Cheng V, Cremonini F. Effects of linaclotide in patients with irritable bowel syndrome with constipation or chronic constipation: A metaanalysis. Clin Gastroenterol Hepatol 2013; 11: 1084-1092e 1083
-
(2013)
Clin Gastroenterol Hepatol
, vol.11
-
-
Videlock, E.J.1
Cheng, V.2
Cremonini, F.3
-
74
-
-
84878471844
-
Activation of guanylate cyclase-C attenuates stretch responses and sensitization of mouse colorectal afferents
-
Feng B, Kiyatkin ME, La JH, et al. Activation of guanylate cyclase-C attenuates stretch responses and sensitization of mouse colorectal afferents. J Neurosci 2013; 33: 9831-9839
-
(2013)
J Neurosci
, vol.33
, pp. 9831-9839
-
-
Feng, B.1
Kiyatkin, M.E.2
La, J.H.3
-
75
-
-
84888293106
-
Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-c and extracellular cyclic guanosine 30,50-monophosphate
-
doi: 10.1053/j.gastro.2013.08.017. [Epub ahead of print
-
Castro J, Harrington AM, Hughes PA, et al. Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-c and extracellular cyclic guanosine 30,50-monophosphate. Gastroenterology 2013. doi: 10.1053/j.gastro.2013.08.017. [Epub ahead of print
-
(2013)
Gastroenterology
-
-
Castro, J.1
Harrington, A.M.2
Hughes, P.A.3
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