Linaclotide improves abdominal pain and bowel habits in a phase IIb study of patients with irritable bowel syndrome with constipation

Gastroenterology

Volumn 139, Issue 6, 2010, Pages

  Johnston, Jeffrey M ^a   Kurtz, Caroline B ^a   MacDougall, James E ^a   Lavins, Bernard J ^a   Currie, Mark G ^a   Fitch, Donald A ^a   O'Dea, Chris ^a   Baird, Mollie ^a   Lembo, Anthony J ^b  

^a IRONWOOD PHARMACEUTICALS INC   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Clinical Trial; Colon; Complete Spontaneous Bowel Movement; Functional Bowel

Indexed keywords

AMINO ACID; ATRIAL NATRIURETIC FACTOR RECEPTOR; LINACLOTIDE; MD 1100; PLACEBO; UNCLASSIFIED DRUG;

ABDOMINAL PAIN; ADULT; AGED; ARTICLE; CLINICAL EVALUATION; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEFECATION HABIT; DIARRHEA; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; HEADACHE; HUMAN; INTESTINE FUNCTION; INTESTINE MOTILITY; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHINOPHARYNGITIS; TREATMENT OUTCOME; UPPER RESPIRATORY TRACT INFECTION; URINARY TRACT INFECTION;

EID: 78649690668     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2010.08.041     Document Type: Article

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