Novel somatic mutations in large granular lymphocytic leukemia affecting the STAT-pathway and T-cell activation

Blood Cancer Journal

Volumn 3, Issue 12, 2013, Pages

  Andersson, E I ^a   Rajala, H L M ^a   Eldfors, S ^b   Ellonen, P ^b   Olson, T ^c   Jerez, A ^d   Clemente, M J ^d   Kallioniemi, O ^b   Porkka, K ^a   Heckman, C ^b   Loughran Jr , T P ^c   Maciejewski, J P ^d   Mustjoki, S ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c PENN STATE CANCER INSTITUTE   (United States)

^d TAUSSIG CANCER INSTITUTE   (United States)

Author keywords

cytotoxic T cells; LGL leukemia; PTPRT; STAT3

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD57 ANTIGEN; CD8 ANTIGEN; RNA; STAT PROTEIN; STAT3 PROTEIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ADULT; AGED; ARTICLE; AUTOIMMUNE DISEASE; BCL11B GENE; CANCER PATIENT; CASE REPORT; CONTROLLED STUDY; CYTOPENIA; CYTOTOXIC T LYMPHOCYTE; EXOME; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GENETIC SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; LARGE GRANULAR LYMPHOCYTE LEUKEMIA; MALE; MIDDLE AGED; MISSENSE MUTATION; NRP1 GENE; ONCOGENE; PHENOTYPE; PTPRT GENE; SLIT2 GENE; SOMATIC MUTATION; STAT3 GENE; STAT5 GENE; T LYMPHOCYTE ACTIVATION; VALIDATION STUDY;

EID: 84892179615     PISSN: None     EISSN: 20445385     Source Type: Journal    
DOI: 10.1038/bcj.2013.65     Document Type: Article

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