Structural stability of human protein tyrosine phosphatase ρ catalytic domain: Effect of point mutations

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Pasquo, Alessandra ^a   Consalvi, Valerio ^b   Knapp, Stefan ^c   Alfano, Ivan ^c   Ardini, Matteo ^b   Stefanini, Simonetta ^b   Chiaraluce, Roberta ^b  

^a ENEA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE RHO; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME STABILITY; MUTANT; POINT MUTATION; PROTEIN EXPRESSION; PROTEIN FOLDING; SINGLE NUCLEOTIDE POLYMORPHISM; THERMODYNAMICS; THERMOSTABILITY; WILD TYPE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; TEMPERATURE;

CATALYTIC DOMAIN; HUMANS; POINT MUTATION; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN TYROSINE PHOSPHATASES; TEMPERATURE;

EID: 84857517538     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032555     Document Type: Article

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