-
1
-
-
0035181636
-
Esterase activity able to hydrolyze dietary antioxidant hydroxycinnamates is distributed along the intestine of mammals
-
Andreasen M.F., et al. Esterase activity able to hydrolyze dietary antioxidant hydroxycinnamates is distributed along the intestine of mammals. J. Agric. Food Chem. 2001, 49:5679-5684.
-
(2001)
J. Agric. Food Chem.
, vol.49
, pp. 5679-5684
-
-
Andreasen, M.F.1
-
2
-
-
84892169189
-
-
United States Army Environmental Hygiene Agency, Aberdeen Proving Ground, MD, USA
-
Asaki A.E., Houpt J.T. Assessment of the developmental toxicity of propylene glycol monomethyl ether acetate (PM acetate) in rats Report USA EHA-75-51-0753-90 1990, United States Army Environmental Hygiene Agency, Aberdeen Proving Ground, MD, USA.
-
(1990)
Assessment of the developmental toxicity of propylene glycol monomethyl ether acetate (PM acetate) in rats Report USA EHA-75-51-0753-90
-
-
Asaki, A.E.1
Houpt, J.T.2
-
3
-
-
84892147706
-
-
BASF, Cleavage of glycol ether acetates by rat plasma in vitro. Unpublished short communication of BASF.
-
BASF, 1985. Cleavage of glycol ether acetates by rat plasma in vitro. Unpublished short communication of BASF.
-
(1985)
-
-
-
4
-
-
79956003626
-
Case studies to test: a framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments
-
Blackburn K., et al. Case studies to test: a framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments. Regul. Toxicol. Pharmacol. 2011, 60:120-135.
-
(2011)
Regul. Toxicol. Pharmacol.
, vol.60
, pp. 120-135
-
-
Blackburn, K.1
-
5
-
-
84892172353
-
Developmental toxicity of inhaled Dipropylene glycol monomethyl ether (DPGME) in rats and rabbits
-
Abstr. 154.
-
Breslin, W.J., et al. (1990). Developmental toxicity of inhaled Dipropylene glycol monomethyl ether (DPGME) in rats and rabbits. Toxicologist 10: 39, Abstr. 154.
-
(1990)
Toxicologist
, vol.10
, pp. 39
-
-
Breslin, W.J.1
-
6
-
-
0014861428
-
Studies on the characterization and localization of rat placental esterases
-
Bulmer D., Fisher A.W.F. Studies on the characterization and localization of rat placental esterases. J. Histochem. Cytochem. 1970, 18:722-729.
-
(1970)
J. Histochem. Cytochem.
, vol.18
, pp. 722-729
-
-
Bulmer, D.1
Fisher, A.W.F.2
-
7
-
-
13544269466
-
Development of a physiologically based pharmacokinetic model for propylene glycol monomethyl ether and its acetate in rats and humans
-
Corley R.A., et al. Development of a physiologically based pharmacokinetic model for propylene glycol monomethyl ether and its acetate in rats and humans. Toxicol. Lett. 2005, 156:193-213.
-
(2005)
Toxicol. Lett.
, vol.156
, pp. 193-213
-
-
Corley, R.A.1
-
8
-
-
0042883950
-
Hydrolysis kinetics of propylene glycol monomethyl ether acetate in rats in vivo and in rat and human tissues in vitro
-
Domoradzki J.Y., Brzak K.A., Thornton C.M. Hydrolysis kinetics of propylene glycol monomethyl ether acetate in rats in vivo and in rat and human tissues in vitro. Toxicol. Sci. 2003, 75:31-39.
-
(2003)
Toxicol. Sci.
, vol.75
, pp. 31-39
-
-
Domoradzki, J.Y.1
Brzak, K.A.2
Thornton, C.M.3
-
9
-
-
84892159554
-
-
EC, Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. Off. J. Eur. Union, L396/1 of 30.12.2006. Commission of the European Communities.
-
EC, (2006). Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC. Off. J. Eur. Union, L396/1 of 30.12.2006. Commission of the European Communities.
-
(2006)
-
-
-
10
-
-
84892176672
-
-
ECETOC, ECETOC Technical Report 0095: The Toxicology of Glycol Ethers and its Relevance to Man, fourth ed. ISSN-0773-8072-95 Brussels.
-
ECETOC, 2005. ECETOC Technical Report 0095: The Toxicology of Glycol Ethers and its Relevance to Man, fourth ed. ISSN-0773-8072-95 Brussels.
-
(2005)
-
-
-
11
-
-
84892184848
-
-
ECETOC, Category Approaches, Read-Across, (Q)SAR. Technical Report No. 116. European Centre for Ecotoxicology and Toxicology of Chemicals, Brussels, Belgium.
-
ECETOC, 2012. Category Approaches, Read-Across, (Q)SAR. Technical Report No. 116. European Centre for Ecotoxicology and Toxicology of Chemicals, Brussels, Belgium.
-
(2012)
-
-
-
12
-
-
84892160440
-
-
ECHA, Technical Guidance Documents for the Implementation of REACH. Guidance on Information Requirements and Chemical Safety Assessment. European Chemicals Agency, Helsinki, Finland.
-
ECHA, 2008. Technical Guidance Documents for the Implementation of REACH. Guidance on Information Requirements and Chemical Safety Assessment. European Chemicals Agency, Helsinki, Finland. http://echa.europa.eu/web/guest/guidance-documents/guidance-on-information-requirements-and-chemical-safety-assessment.
-
(2008)
-
-
-
13
-
-
84892161289
-
-
ECHA, Evaluation under REACH, Progress Report 2011. ECHA-12-R-02-EN, ISSN: 978-92-9217-643-3.
-
ECHA, 2012. Evaluation under REACH, Progress Report 2011. ECHA-12-R-02-EN, ISSN: 978-92-9217-643-3.
-
(2012)
-
-
-
14
-
-
84892180072
-
-
ECHA, Evaluation under REACH, Progress Report 2012. ECHA-13-A-01-EN, ISSN: 1831-6506.
-
ECHA, 2013a. Evaluation under REACH, Progress Report 2012. ECHA-13-A-01-EN, ISSN: 1831-6506.
-
(2013)
-
-
-
15
-
-
84892189214
-
-
ECHA, Decision of the Board of Appeal of the European Chemicals Agency on case A-001-2012.
-
ECHA, (2013b). Decision of the Board of Appeal of the European Chemicals Agency on case A-001-2012. http://echa.europa.eu/documents/10162/13575/a_001_2012_boa_decision_en.pdf.
-
(2013)
-
-
-
16
-
-
84892142161
-
-
ECHA, Grouping of Substances and Read-Across, Practical Guide and Case Study.
-
ECHA, (2013c). Grouping of Substances and Read-Across, Practical Guide and Case Study. http://echa.europa.eu/en/support/grouping-of-substances-and-read-across.
-
(2013)
-
-
-
17
-
-
0016627576
-
Metabolism of ethyl acetate in the rat: hydrolysis of ethyl alcohol in vitro and in vivo
-
Gallaher E.J., Loomis T.A. Metabolism of ethyl acetate in the rat: hydrolysis of ethyl alcohol in vitro and in vivo. Toxicol. Appl. Pharmacol. 1975, 34:309-313.
-
(1975)
Toxicol. Appl. Pharmacol.
, vol.34
, pp. 309-313
-
-
Gallaher, E.J.1
Loomis, T.A.2
-
18
-
-
0034658004
-
A toxicokinetic study of inhaled ethylene glycol ethyl ether acetate and validation of a physiologically based pharmacokinetic model for rat and human
-
Gargas M.L., et al. A toxicokinetic study of inhaled ethylene glycol ethyl ether acetate and validation of a physiologically based pharmacokinetic model for rat and human. Toxicol. Appl. Pharmacol. 2000, 165:63-73.
-
(2000)
Toxicol. Appl. Pharmacol.
, vol.165
, pp. 63-73
-
-
Gargas, M.L.1
-
19
-
-
0022394307
-
Hydrolase cytochemistry in murine rodent decidua, yolk sac, and placenta with special reference to proteases
-
Graf R., Gossrau R. Hydrolase cytochemistry in murine rodent decidua, yolk sac, and placenta with special reference to proteases. Zeitschrift fuer Mikroskopisch-Anatomische Forschung 1985, 99(6):959-984.
-
(1985)
Zeitschrift fuer Mikroskopisch-Anatomische Forschung
, vol.99
, Issue.6
, pp. 959-984
-
-
Graf, R.1
Gossrau, R.2
-
20
-
-
77957344287
-
Prediction of human metabolic clearance from in vitro systems: retrospective analysis and prospective view
-
Hallifax D., Foster J.A., Houston J.B. Prediction of human metabolic clearance from in vitro systems: retrospective analysis and prospective view. Pharm. Res. 2010, 27:2150-2161.
-
(2010)
Pharm. Res.
, vol.27
, pp. 2150-2161
-
-
Hallifax, D.1
Foster, J.A.2
Houston, J.B.3
-
21
-
-
77957179288
-
Teratologic evaluation of inhaled propylene glycol monomethyl ether in rats and rabbits
-
Hanley T.R., et al. Teratologic evaluation of inhaled propylene glycol monomethyl ether in rats and rabbits. Fundam. Appl. Toxicol. 1984, 4:784-794.
-
(1984)
Fundam. Appl. Toxicol.
, vol.4
, pp. 784-794
-
-
Hanley, T.R.1
-
22
-
-
0015232557
-
Proximal to distal variations in enzymes of the rat intestine
-
Harrison D.D., Webster H.L. Proximal to distal variations in enzymes of the rat intestine. Biochmica et Biophys Acta 1971, 244:432-436.
-
(1971)
Biochmica et Biophys Acta
, vol.244
, pp. 432-436
-
-
Harrison, D.D.1
Webster, H.L.2
-
23
-
-
79851489459
-
The role of intestinal carboxylesterase in the oral absorption of prodrugs
-
Imai T., Ohura K. The role of intestinal carboxylesterase in the oral absorption of prodrugs. Curr. Drug Metab. 2010, 11:793-805.
-
(2010)
Curr. Drug Metab.
, vol.11
, pp. 793-805
-
-
Imai, T.1
Ohura, K.2
-
24
-
-
0018386988
-
Species differences and characterization of intestinal esterase on the hydrolyzing activity of ester-type drugs
-
Inoue M., et al. Species differences and characterization of intestinal esterase on the hydrolyzing activity of ester-type drugs. Jpn. J. Pharmacol. 1979, 29:9-16.
-
(1979)
Jpn. J. Pharmacol.
, vol.29
, pp. 9-16
-
-
Inoue, M.1
-
26
-
-
0017665777
-
The hydrolysis of flavouring esters by artificial gastrointestinal juices and rat tissue preparations
-
Longland R.C., Shilling W.H., Gangolli S.D. The hydrolysis of flavouring esters by artificial gastrointestinal juices and rat tissue preparations. Toxicology 1977, 8:197-204.
-
(1977)
Toxicology
, vol.8
, pp. 197-204
-
-
Longland, R.C.1
Shilling, W.H.2
Gangolli, S.D.3
-
27
-
-
0027449673
-
Nature and role of xenobiotic metabolizing esterases in rat liver, lung, skin and blood
-
McCracken N.W., Blain P.G., Williams F.M. Nature and role of xenobiotic metabolizing esterases in rat liver, lung, skin and blood. Biochem. Pharmacol. 1993, 45:31-36.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 31-36
-
-
McCracken, N.W.1
Blain, P.G.2
Williams, F.M.3
-
28
-
-
0019784995
-
Comparative short-term inhalation toxicity of ethylene glycol monomethyl ether and propylene glycol monomethyl ether in rats and mice
-
Miller R.R., et al. Comparative short-term inhalation toxicity of ethylene glycol monomethyl ether and propylene glycol monomethyl ether in rats and mice. Toxicol. Appl. Pharmacol. 1981, 61:368-377.
-
(1981)
Toxicol. Appl. Pharmacol.
, vol.61
, pp. 368-377
-
-
Miller, R.R.1
-
29
-
-
0020679814
-
Comparative metabolism and disposition of ethylene glycol monomethyl ether and propylene glycol monomethyl ether in male rats
-
Miller R.R., et al. Comparative metabolism and disposition of ethylene glycol monomethyl ether and propylene glycol monomethyl ether in male rats. Toxicol. Appl. Pharmacol. 1983, 67:229-237.
-
(1983)
Toxicol. Appl. Pharmacol.
, vol.67
, pp. 229-237
-
-
Miller, R.R.1
-
30
-
-
0021176250
-
Propylene glycol monomethyl ether acetate (PGMEA) metabolism, disposition, and short-term vapour inhalation toxicity studies
-
Miller R.R., et al. Propylene glycol monomethyl ether acetate (PGMEA) metabolism, disposition, and short-term vapour inhalation toxicity studies. Toxicol. Appl. Pharmacol. 1984, 75:521-530.
-
(1984)
Toxicol. Appl. Pharmacol.
, vol.75
, pp. 521-530
-
-
Miller, R.R.1
-
31
-
-
0022399072
-
Metabolism and disposition of dipropylene glycol monomethyl ether (DPGME) in male rats
-
Miller R.R., et al. Metabolism and disposition of dipropylene glycol monomethyl ether (DPGME) in male rats. Fundam. Appl. Toxicol. 1985, 1985(5):721-726.
-
(1985)
Fundam. Appl. Toxicol.
, vol.1985
, Issue.5
, pp. 721-726
-
-
Miller, R.R.1
-
32
-
-
84892177369
-
-
Ministry of Health and Welfare Japan, Chemicals Investigation Promoting Council, office of Environmental Chemicals Safety, Environmental Health Bureau, Ministry of Health and Welfare, Japan
-
Toxicity testing reports of environmental chemicals 6. Propylene glycol monomethyl ether acetate 1998, 205-223. Ministry of Health and Welfare Japan, Chemicals Investigation Promoting Council, office of Environmental Chemicals Safety, Environmental Health Bureau, Ministry of Health and Welfare, Japan.
-
(1998)
Toxicity testing reports of environmental chemicals 6. Propylene glycol monomethyl ether acetate
, pp. 205-223
-
-
-
33
-
-
0023263384
-
Nonlinear kinetics of inhaled propylene glycol monometyl ether in fischer 344 rats following single and repeated exposures
-
Morgott D.A., Nolan R.J. Nonlinear kinetics of inhaled propylene glycol monometyl ether in fischer 344 rats following single and repeated exposures. Toxicol. Appl. Pharmacol. 1987, 89:19-28.
-
(1987)
Toxicol. Appl. Pharmacol.
, vol.89
, pp. 19-28
-
-
Morgott, D.A.1
Nolan, R.J.2
-
34
-
-
84892188044
-
-
OECD, SIDS Initial Assessment Report for SIAM 17: Propylene Glycol Ethers. Available at:.
-
OECD, 2003. SIDS Initial Assessment Report for SIAM 17: Propylene Glycol Ethers. Available at:. http://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html.
-
(2003)
-
-
-
37
-
-
84879829369
-
Use of category approaches, read-across and (Q)SAR: general considerations
-
Patlewicz G. Use of category approaches, read-across and (Q)SAR: general considerations. Regu. Toxicol. Pharmacol. 2013, 67:1-12.
-
(2013)
Regu. Toxicol. Pharmacol.
, vol.67
, pp. 1-12
-
-
Patlewicz, G.1
-
38
-
-
84872410355
-
Workshop: use of ''read-across'' for chemical safety assessment under REACH
-
Patlewicz G., et al. Workshop: use of ''read-across'' for chemical safety assessment under REACH. Regul. Toxicol. Pharmacol. 2013, 65:226-228.
-
(2013)
Regul. Toxicol. Pharmacol.
, vol.65
, pp. 226-228
-
-
Patlewicz, G.1
-
39
-
-
23944451585
-
A unified model for predicting human hepatic, metabolic clearance from in vitro intrinsic clearance data in hepatocytes and microsomes
-
Riley R.J., McGinnity D.F., Austin R.P. A unified model for predicting human hepatic, metabolic clearance from in vitro intrinsic clearance data in hepatocytes and microsomes. Drug Metab. Dispos. 2005, 33:1304-1311.
-
(2005)
Drug Metab. Dispos.
, vol.33
, pp. 1304-1311
-
-
Riley, R.J.1
McGinnity, D.F.2
Austin, R.P.3
-
40
-
-
73949132615
-
Re-evaluation of animal numbers and costs for in vivo tests to accomplish REACH legislation requirements for chemicals - a report by the transatlantic think tank for toxicology (t(4))
-
Rovida C., Hartung T. Re-evaluation of animal numbers and costs for in vivo tests to accomplish REACH legislation requirements for chemicals - a report by the transatlantic think tank for toxicology (t(4)). ALTEX 2009, 26(3):187-208.
-
(2009)
ALTEX
, vol.26
, Issue.3
, pp. 187-208
-
-
Rovida, C.1
Hartung, T.2
-
41
-
-
0031800635
-
The mammalian carboxylesterases: from molecules to functions
-
Satoh T., Hosokawa M. The mammalian carboxylesterases: from molecules to functions. Annu. Rev. Pharmacol. Toxicol. 1998, 38:257-288.
-
(1998)
Annu. Rev. Pharmacol. Toxicol.
, vol.38
, pp. 257-288
-
-
Satoh, T.1
Hosokawa, M.2
-
42
-
-
77957184091
-
Hydrolysis of several glycol ether acetates and acrylate esters by nasal mucosal carboxylesterase in vitro
-
Stott W.T., McKenna M.J. Hydrolysis of several glycol ether acetates and acrylate esters by nasal mucosal carboxylesterase in vitro. Fundam. Appl. Toxicol. 1985, 5:399-404.
-
(1985)
Fundam. Appl. Toxicol.
, vol.5
, pp. 399-404
-
-
Stott, W.T.1
McKenna, M.J.2
-
43
-
-
77955919399
-
Use of read-across and tiered exposure assessment in risk assessment under REACH
-
Vink S.R., et al. Use of read-across and tiered exposure assessment in risk assessment under REACH. Regul. Toxicol. Pharmacol. 2010, 58:64-71.
-
(2010)
Regul. Toxicol. Pharmacol.
, vol.58
, pp. 64-71
-
-
Vink, S.R.1
-
44
-
-
0017798621
-
Acetylesterase isoenzymes in rat uterus and placenta
-
White L.R. Acetylesterase isoenzymes in rat uterus and placenta. Histochem. J. 1978, 10(2):151-157.
-
(1978)
Histochem. J.
, vol.10
, Issue.2
, pp. 151-157
-
-
White, L.R.1
-
45
-
-
75549092069
-
A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments
-
Wu S., et al. A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments. Regul. Toxicol. Pharmacol. 2010, 56:67-81.
-
(2010)
Regul. Toxicol. Pharmacol.
, vol.56
, pp. 67-81
-
-
Wu, S.1
|